LOCUS       NM_001017383            1801 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus peptidylprolyl isomerase like 2 (Ppil2), mRNA.
ACCESSION   NM_001017383 XM_341018
VERSION     NM_001017383.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1801)
  AUTHORS   Davis,T.L., Walker,J.R., Campagna-Slater,V., Finerty,P.J.,
            Paramanathan,R., Bernstein,G., MacKenzie,F., Tempel,W., Ouyang,H.,
            Lee,W.H., Eisenmesser,E.Z. and Dhe-Paganon,S.
  TITLE     Structural and biochemical characterization of the human
            cyclophilin family of peptidyl-prolyl isomerases
  JOURNAL   PLoS Biol 8 (7), e1000439 (2010)
   PUBMED   20676357
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1801)
  AUTHORS   Mesa,A., Somarelli,J.A. and Herrera,R.J.
  TITLE     Spliceosomal immunophilins
  JOURNAL   FEBS Lett 582 (16), 2345-2351 (2008)
   PUBMED   18544344
  REMARK    Review article
REFERENCE   3  (bases 1 to 1801)
  AUTHORS   Pushkarsky,T., Yurchenko,V., Vanpouille,C., Brichacek,B.,
            Vaisman,I., Hatakeyama,S., Nakayama,K.I., Sherry,B. and
            Bukrinsky,M.I.
  TITLE     Cell surface expression of CD147/EMMPRIN is regulated by
            cyclophilin 60
  JOURNAL   J Biol Chem 280 (30), 27866-27871 (2005)
   PUBMED   15946952
REFERENCE   4  (bases 1 to 1801)
  AUTHORS   Hatakeyama,S., Yada,M., Matsumoto,M., Ishida,N. and Nakayama,K.I.
  TITLE     U box proteins as a new family of ubiquitin-protein ligases
  JOURNAL   J Biol Chem 276 (35), 33111-33120 (2001)
   PUBMED   11435423
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC085890.1.
            
            On Apr 22, 2005 this sequence version replaced XM_341018.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC085890.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132262, SAMD00132263
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1801
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q23"
     gene            1..1801
                     /gene="Ppil2"
                     /note="peptidylprolyl isomerase like 2"
                     /db_xref="GeneID:360746"
                     /db_xref="RGD:1309484"
     exon            1..76
                     /gene="Ppil2"
                     /inference="alignment:Splign:2.1.0"
     CDS             45..1610
                     /gene="Ppil2"
                     /EC_number="5.2.1.8"
                     /note="peptidyl-prolyl cis-trans isomerase-like 2;
                     peptidylprolyl isomerase (cyclophilin)-like 2"
                     /codon_start=1
                     /product="RING-type E3 ubiquitin-protein ligase PPIL2"
                     /protein_id="NP_001017383.1"
                     /db_xref="GeneID:360746"
                     /db_xref="RGD:1309484"
                     /translation="MGKRQHQKDKMYITCAEYTHFYGGRKPDITQTSFRRLPFDHCSL
                     SLQPFVYPVCTPEGVVFDLLNIVPWLKKYGTDPSTGEKLDGKSLIKLNFAKNSEGQYH
                     CPVLYSVFTDNTHIVAIRTTGNVYTYEAVEQLNIKAKNLRDLLTDEPFSRQDIITLQD
                     PTNLDKFNVSSFFHVKNNMRMIDPDEEKAKQDPSYYLKNTNAETRETLQELYKEFKGD
                     EILAATMKPPEKKKVDQLNAAHYSTGKVSASFTSTAMVPETTHEAAVIDEDVLRYQFV
                     KKKGYVRLHTNKGDLNLELHCDLTPKTCENFIKLCKKQYYDGTIFHRSIRNFVIQGGD
                     PTGTGTGGESYWGKPFKDEFRPNLSHTGRGVLSMANSGPNTNKSQFFITFRSCAYLDK
                     KHTIFGRVVGGFDTLTAMENVESDPKTDRPKEEVRICTTTVFVDPYEEADAQIAQERK
                     KTQHQVDPEAKAKTNQPQPGNQGPQTYRQGVGKYINPAATKRAAEEEPSTSTAIPTAK
                     KRPSRGFGDFSSW"
     exon            77..126
                     /gene="Ppil2"
                     /inference="alignment:Splign:2.1.0"
     exon            127..172
                     /gene="Ppil2"
                     /inference="alignment:Splign:2.1.0"
     exon            173..235
                     /gene="Ppil2"
                     /inference="alignment:Splign:2.1.0"
     exon            236..287
                     /gene="Ppil2"
                     /inference="alignment:Splign:2.1.0"
     exon            288..339
                     /gene="Ppil2"
                     /inference="alignment:Splign:2.1.0"
     exon            340..431
                     /gene="Ppil2"
                     /inference="alignment:Splign:2.1.0"
     exon            432..521
                     /gene="Ppil2"
                     /inference="alignment:Splign:2.1.0"
     exon            522..597
                     /gene="Ppil2"
                     /inference="alignment:Splign:2.1.0"
     exon            598..758
                     /gene="Ppil2"
                     /inference="alignment:Splign:2.1.0"
     exon            759..834
                     /gene="Ppil2"
                     /inference="alignment:Splign:2.1.0"
     exon            835..941
                     /gene="Ppil2"
                     /inference="alignment:Splign:2.1.0"
     exon            942..1031
                     /gene="Ppil2"
                     /inference="alignment:Splign:2.1.0"
     exon            1032..1065
                     /gene="Ppil2"
                     /inference="alignment:Splign:2.1.0"
     exon            1066..1183
                     /gene="Ppil2"
                     /inference="alignment:Splign:2.1.0"
     exon            1184..1240
                     /gene="Ppil2"
                     /inference="alignment:Splign:2.1.0"
     exon            1241..1313
                     /gene="Ppil2"
                     /inference="alignment:Splign:2.1.0"
     exon            1314..1376
                     /gene="Ppil2"
                     /inference="alignment:Splign:2.1.0"
     exon            1377..1513
                     /gene="Ppil2"
                     /inference="alignment:Splign:2.1.0"
     exon            1514..1776
                     /gene="Ppil2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgctagagcc tgagtgtctg ctgtgatctc ggttcgtcgc caccatgggg aagcgacagc
       61 accagaagga caagatgtac atcacctgtg cagagtacac tcatttctat ggtggcagga
      121 agccagatat cacacagaca agttttcgcc gcttaccttt tgaccattgc agtctctctc
      181 tccagccttt tgtctaccca gtctgcaccc cggaaggtgt cgtcttcgac ttgctgaaca
      241 ttgtcccatg gcttaagaag tatgggaccg atccgagcac tggagagaaa cttgatggga
      301 agtccctgat taagctgaac tttgcaaaga acagtgaagg gcagtaccac tgtccagtgc
      361 tgtactccgt gttcactgac aacacccaca tcgtggccat caggacaact ggcaatgtct
      421 acacctatga ggcagtggag cagctaaaca tcaaggccaa gaacttgagg gacctgttaa
      481 ctgatgagcc cttttccagg caagacatca tcaccctgca ggaccccacc aatctggaca
      541 aatttaacgt cagcagcttc ttccatgtaa agaataacat gcgaatgata gatccagatg
      601 aggaaaaggc caaacaagac ccatcttatt atttgaaaaa tacaaatgcg gagacccgag
      661 agacgctaca ggagctctac aaagagttca aaggagatga gattttagca gctaccatga
      721 agccacctga gaagaagaag gtggaccaac tgaatgccgc ccactattcc acagggaagg
      781 tcagcgcgtc cttcacctct accgccatgg tgcctgagac cacgcatgaa gcagctgtca
      841 ttgatgaaga tgtcctgcgc taccagtttg tgaagaagaa gggctatgtg aggctacaca
      901 ccaacaaggg tgacctcaac ctcgagctgc actgtgacct gacaccaaaa acctgtgaaa
      961 acttcatcaa gctctgcaag aaacagtatt atgatggtac catctttcac agatccatca
     1021 ggaactttgt gatccagggt ggtgacccta ctggtacagg cacaggagga gagtcatact
     1081 ggggcaagcc tttcaaagac gagttccgtc ccaatctttc acacacaggc cgtggggtgc
     1141 tcagcatggc caattcaggg cccaacacca acaagtctca gttcttcatc accttccggt
     1201 cctgtgctta cctggacaag aagcacacca tctttggacg ggttgtcggg ggctttgaca
     1261 cgctgacagc tatggagaat gtggagagtg accccaaaac tgaccgccct aaggaagaag
     1321 tgcgcatctg taccaccaca gtgtttgtgg atccctatga ggaggccgac gcccagattg
     1381 cccaggaacg gaagaagaca cagcaccaag tggatccaga ggccaaggcc aagacgaacc
     1441 agccccagcc tggaaaccag ggcccccaga cataccgcca gggggtgggc aagtacatca
     1501 accctgcagc cacgaaacga gcagcagagg aagaaccatc caccagcaca gctatcccca
     1561 cagccaagaa aaggcccagt cggggctttg gggacttcag ctcctggtag cagcaggctg
     1621 gcctcaggga tcctggtagg ggtgcagggc tgtgggcctc caggtctgtc cctgagccct
     1681 ttacccttgc catcagtttg ggctgtgaac caataaatct gttgcctagg acctgggtcc
     1741 agtttgggcc cctgggactc ctgggatccc cttcctaaaa aaaaaaaaaa aaaaaaaaaa
     1801 a
//
