LOCUS       NM_001395638            4873 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus PPFIA binding protein 1 (Ppfibp1), mRNA.
ACCESSION   NM_001395638
VERSION     NM_001395638.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4873)
  AUTHORS   Guo,Z., Neilson,L.J., Zhong,H., Murray,P.S., Zanivan,S. and
            Zaidel-Bar,R.
  TITLE     E-cadherin interactome complexity and robustness resolved by
            quantitative proteomics
  JOURNAL   Sci Signal 7 (354), rs7 (2014)
   PUBMED   25468996
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4873)
  AUTHORS   Kuo,J.C., Han,X., Hsiao,C.T., Yates,J.R. 3rd and Waterman,C.M.
  TITLE     Analysis of the myosin-II-responsive focal adhesion proteome
            reveals a role for beta-Pix in negative regulation of focal
            adhesion maturation
  JOURNAL   Nat Cell Biol 13 (4), 383-393 (2011)
   PUBMED   21423176
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643295.20254.1,
                                           SRR26643287.12488.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on computational evidence
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-169               JAXUCZ010000004.1  181539466-181539634
            170-256             JAXUCZ010000004.1  181586267-181586353
            257-355             JAXUCZ010000004.1  181626474-181626572
            356-561             JAXUCZ010000004.1  181629024-181629229
            562-648             JAXUCZ010000004.1  181638434-181638520
            649-762             JAXUCZ010000004.1  181639866-181639979
            763-894             JAXUCZ010000004.1  181641152-181641283
            895-987             JAXUCZ010000004.1  181645769-181645861
            988-1102            JAXUCZ010000004.1  181647509-181647623
            1103-1164           JAXUCZ010000004.1  181650103-181650164
            1165-1240           JAXUCZ010000004.1  181651279-181651354
            1241-1395           JAXUCZ010000004.1  181654902-181655056
            1396-1511           JAXUCZ010000004.1  181660024-181660139
            1512-1568           JAXUCZ010000004.1  181660956-181661012
            1569-1632           JAXUCZ010000004.1  181662469-181662532
            1633-1662           JAXUCZ010000004.1  181662921-181662950
            1663-1834           JAXUCZ010000004.1  181665945-181666116
            1835-1982           JAXUCZ010000004.1  181668650-181668797
            1983-2111           JAXUCZ010000004.1  181669074-181669202
            2112-2262           JAXUCZ010000004.1  181670722-181670872
            2263-2374           JAXUCZ010000004.1  181671547-181671658
            2375-2463           JAXUCZ010000004.1  181671767-181671855
            2464-2586           JAXUCZ010000004.1  181675449-181675571
            2587-2712           JAXUCZ010000004.1  181676251-181676376
            2713-2901           JAXUCZ010000004.1  181677334-181677522
            2902-3078           JAXUCZ010000004.1  181679647-181679823
            3079-3144           JAXUCZ010000004.1  181680084-181680149
            3145-4873           JAXUCZ010000004.1  181680351-181682079
FEATURES             Location/Qualifiers
     source          1..4873
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q44"
     gene            1..4873
                     /gene="Ppfibp1"
                     /note="PPFIA binding protein 1"
                     /db_xref="GeneID:312855"
                     /db_xref="RGD:1310010"
     exon            1..169
                     /gene="Ppfibp1"
                     /inference="alignment:Splign:2.1.0"
     exon            170..256
                     /gene="Ppfibp1"
                     /inference="alignment:Splign:2.1.0"
     exon            257..355
                     /gene="Ppfibp1"
                     /inference="alignment:Splign:2.1.0"
     CDS             292..3231
                     /gene="Ppfibp1"
                     /note="PTPRF interacting protein, binding protein 1
                     (liprin beta 1)"
                     /codon_start=1
                     /product="liprin-beta-1"
                     /protein_id="NP_001382567.1"
                     /db_xref="GeneID:312855"
                     /db_xref="RGD:1310010"
                     /translation="MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMG
                     SLRALHLVEDLRGLLEMMETDEKEGLRCQIPDSTAEMLIEWLQNQMTNGHLPGNGDVY
                     QERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELL
                     SRTSLETQKLELMAEISNLKLKLTAVEKDRLDYEDRFRDTEGLIQEINDLRLKVNEMD
                     SERLQYEKKLKSTKDELASLKEQLEEKECEVKRLQERLVCKTKGEGVEILDRDIEVQK
                     MKKAVESLMAANEEKERKIEDLRQCLSRYRKVQDPAALAQGQEGECEGLFHSSSISTL
                     LDAQGFSDLERSTSSTPGMGSPSRDPLHTSAPEEFHTSVLQASVPSLFPTSMDEETCE
                     KPKLATKPETSFEEGDGRAVLGADAEVSLSDGVSTSSLQKSSSLGNLKKETSDGVEKE
                     SIQKPPEDKTPTDSHTFGTLPPKAPGHGASVDDSPFGTRKARSSFGRGFFKIKSGKRT
                     ASAPNLAETEKETDEHLDLAGTSRPKGSQGTSPFQMSPPSPDSRKKSRGIMRLFGKLR
                     RSQSTTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDTPFAKWTKEQVCSW
                     LAEQGLGSYLSSGKHWIMSGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEE
                     TNYGKLDFNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLS
                     IKRAIQVLRINNFEPNCLRRRPSDENSITPSEVQQWTNHRVMEWLRSVDLAEYAPNLR
                     GSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAME
                     LPDYVLLTATAKVKPKKLTFSNFGNLRKKKHEDGEEYVCPMELGQASGSSQKGFRPGL
                     DMRLYEEDDLDRLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASI
                     TDEDSNV"
     exon            356..561
                     /gene="Ppfibp1"
                     /inference="alignment:Splign:2.1.0"
     exon            562..648
                     /gene="Ppfibp1"
                     /inference="alignment:Splign:2.1.0"
     exon            649..762
                     /gene="Ppfibp1"
                     /inference="alignment:Splign:2.1.0"
     exon            763..894
                     /gene="Ppfibp1"
                     /inference="alignment:Splign:2.1.0"
     exon            895..987
                     /gene="Ppfibp1"
                     /inference="alignment:Splign:2.1.0"
     exon            988..1102
                     /gene="Ppfibp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1103..1164
                     /gene="Ppfibp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1165..1240
                     /gene="Ppfibp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1241..1395
                     /gene="Ppfibp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1396..1511
                     /gene="Ppfibp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1512..1568
                     /gene="Ppfibp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1569..1632
                     /gene="Ppfibp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1633..1662
                     /gene="Ppfibp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1663..1834
                     /gene="Ppfibp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1835..1982
                     /gene="Ppfibp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1983..2111
                     /gene="Ppfibp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2112..2262
                     /gene="Ppfibp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2263..2374
                     /gene="Ppfibp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2375..2463
                     /gene="Ppfibp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2464..2586
                     /gene="Ppfibp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2587..2712
                     /gene="Ppfibp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2713..2901
                     /gene="Ppfibp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2902..3078
                     /gene="Ppfibp1"
                     /inference="alignment:Splign:2.1.0"
     exon            3079..3144
                     /gene="Ppfibp1"
                     /inference="alignment:Splign:2.1.0"
     exon            3145..4873
                     /gene="Ppfibp1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aggcggcacc tgggcggcgg tgatgtcagc cgggcgctgt gctcgggccc cggctcctgt
       61 cgccgtgtag ggcgcggggg cggccgcgac gggagcggcg atctggcagc cgggcgggtg
      121 ccgggaggcg gaactgcaac ttgtggagct cggcggccct tcgcctcagt accgaacttc
      181 tatggatcag tttgctaagg acgtgcaaga ttgggagagc tgagaaatca acgttgaacc
      241 tgtttttttc ttaaaagttg aagctggaat ttgccccttt cgagcaggaa gatgatgagc
      301 gacgctagtg acatgctggc cgcggcgctg gagcagatgg acgggatcat agcaggttct
      361 aaagccttgg aatattccaa tgggatcttt gattgtcaat ctcccacctc cccatttatg
      421 ggaagcttgc gagctctgca ccttgtggaa gacctgcgtg gattgctgga gatgatggaa
      481 acggatgaga aagaaggatt gagatgccag attccagact caacagctga aatgctgatt
      541 gagtggcttc aaaatcaaat gacaaatgga cacctacctg ggaatggaga tgtgtatcaa
      601 gaaaggctag cacggctaga aaacgacaag gagtccctcg ttcttcaggt gagcgtgttg
      661 acagaccagg tggaggctca gggagagaag attcgggatt tggagttctg tcttgaagag
      721 catagagaga agctgaatgc cactgaagaa atgctgcagc aggagcttct gagtaggact
      781 tccttagaga cacagaagct ggagctgatg gctgagatct ctaacttgaa gttaaaactg
      841 accgccgtag agaaggacag gctggattat gaagataggt tcagagacac agaggggcta
      901 atacaagaga tcaatgattt gaggctaaaa gtcaatgaga tggacagtga aagacttcag
      961 tatgaaaaaa agctcaagtc aactaaagat gaactggcgt ctttaaaaga gcagctggag
     1021 gagaaggagt gtgaagtgaa gagactgcag gagagactgg tttgtaagac gaaaggagaa
     1081 ggggtcgaaa tcctcgatcg agacattgaa gtacagaaaa tgaagaaggc agtggagtct
     1141 ctgatggcag caaacgagga aaaggagcgg aaaatagaag acctccggca gtgcctgagc
     1201 aggtacagga aagtgcagga cccagcagct ctggcccaag gccaggaggg cgagtgtgag
     1261 ggcctgttcc actccagttc tatctccacc ctgttggacg cacagggctt tagtgatctg
     1321 gagagaagca cttcttctac gccaggaatg gggtctccca gcagggaccc gctccacacc
     1381 agtgccccag aggagtttca caccagcgtc ctccaagctt cagttccttc gctatttccg
     1441 acatctatgg acgaagaaac ctgtgagaaa cccaagctgg ctactaagcc tgagacttcg
     1501 tttgaagagg gtgatggaag agcagtcctc ggtgctgacg ctgaagtctc cctaagtgat
     1561 ggtgtctcaa cttcgagtct gcagaaatcc agtagccttg gaaatctgaa gaaagagaca
     1621 tcagatggcg tggaaaagga gtctatccag aagcctccag aggataaaac tccgaccgac
     1681 agccacacat ttgggaccct gcctcccaaa gctccaggac atggcgcctc tgtggatgac
     1741 agcccctttg gcactcgaaa agccaggtct tcctttggcc ggggcttttt caaaatcaaa
     1801 agtgggaaga ggacagcgag tgcaccaaac ctcgctgaga cagaaaaaga gacagatgag
     1861 cacctagatt tggctggtac atctcggcca aaaggttcac agggaaccag tccgttccag
     1921 atgtcgccac catctccaga ttccagaaag aaatccagag gcatcatgcg actctttggg
     1981 aaacttagaa gaagtcagtc aactacattc aacccagatg acatgtctga gcctgaattc
     2041 aaaagaggag ggacaagggc aactgcagga cccaggcttg gttggtctcg agatttagga
     2101 cagtccaaca gtgacctgga cacgccgttt gcaaagtgga ccaaggagca ggtgtgcagc
     2161 tggctggcag aacaaggcct gggctcctac ctgagttccg gcaagcattg gattatgtct
     2221 ggccagacgc ttttgcaggc ttctcagcaa gacctagaga aggagcttgg catcaagcac
     2281 tcactgcatc gaaagaagct ccagttggcc ctgcaggccc tgggatctga agaagagacc
     2341 aactacggaa agctagactt caactgggtc actagatggc tggatgatat tggcctccct
     2401 cagtacaaga cgcagtttga tgaggggcgg gtggacggcc gaatgctaca ctacatgact
     2461 gtggatgacc tcctgtccct gaaggttgtg agtgtgctgc accatctcag tatcaaaagg
     2521 gccatccaag tcctgaggat caataacttc gagccaaact gtcttcggag gcggccgtct
     2581 gacgagaaca gcatcacccc atctgaggtt cagcagtgga ccaatcatcg tgtgatggag
     2641 tggctgcgct ctgtggactt ggcagaatat gcccccaacc tcagaggcag tggtgtccat
     2701 ggagggctca tggttcttga gcctcgtttt aacgtagaaa ctatggctca gttattgaac
     2761 attcctccaa acaaaacctt gttgcgcaga catttggcta cccatttcaa ccttctgatt
     2821 ggtgctgagg cccagcacca gaagcgagat gccatggagt taccagatta tgtcctgcta
     2881 acagctactg ccaaagtgaa gccaaagaaa ctgaccttta gcaactttgg gaatctgagg
     2941 aagaagaaac atgaagatgg ggaggagtat gtctgtccaa tggagctagg ccaggcgtcg
     3001 ggtagctccc agaaggggtt tagacctggc ttggacatgc gcctgtatga agaggatgat
     3061 ttggaccggt tagagcagat ggaagattca gaagggacgg tgagacagat aggtgcgttt
     3121 tctgaaggca tcaacaatct cacgcacatg ttaaaggaag atgacatgtt taaggatttt
     3181 gctgcccgct ccccaagtgc cagcatcaca gatgaagact ccaacgtttg agcagagcac
     3241 ctgggcaaat gccaggagca cacgtgtcat tttccagctt tgtttctcgg atagtgtata
     3301 cagcaggtga caggttgtgc attgcttatt gttcggactt ctgctcgctc agaaggagag
     3361 ctatagcacg ggaatggtgc cagttctgag catgttgagg aaaaagagag gctggtgagc
     3421 gaaagtgcgc ttgctctgcc tctgtttaat gcgaagtctg cgacgtgtgc tgttggaagt
     3481 gttgcacgca cggttgcgtg taccagagcg cctcgctcac atctccagga gggaggcctg
     3541 gccacatcag tgttcactgc agccggctgt gctgaacgtg ctgcccccag agccaagtgc
     3601 caccatgtgc cagcagcacc gccacttgcc tctcactgtc ttatttttat atatttttct
     3661 aaatacgtgt atatatgcag tctacagaaa acagaacctt tattttgtga cacaaggatc
     3721 aaaagatcat attaaaacaa agaaaccccc gtgttcccta tgatcacata ccagctgatt
     3781 cttgcgggta ccacagtccc attttatctc cactgatgaa ttttaaccgt gttaaccact
     3841 caggctaaat tctacatgat gtatacttct tggttcccac caaaattgtc gagcagctta
     3901 gaacttgaac tttaatcccg actccatttt cttcataatg aagtatttta gggttgttac
     3961 cacatcagct tgaagccttc ggatacactc atgtccccat cagaaaagtt ttctgttaga
     4021 atggcttcag aaaaacaaga aaccaaacag aacctttcca tgttaacttc cttatttctt
     4081 tttctttgct aaactcatca ttatgttgaa ctaaggggtc cacctagcca tgtccactgt
     4141 acctgatact cagcctgtca gctcacaggg cttcagatta tttcagtcaa atcccagtat
     4201 tttaaagctg cattagaaca ttttctgatg gtcctgacca gtagcacgtc gctcgtgttt
     4261 tctgtaacac aaggcccaag ggctttttgt aaagaaaata gaaagttaca gcagctgctc
     4321 tgtggcgtgt ggatgcaagt gtttctagtg gtgttggaga caatcctctt tttattcagg
     4381 gctgctcaaa acgagacctc ctgtgttcca gacaggagct tacacaccag gggacagggg
     4441 gacagttcgg tttgtggtga tggccatttc caaatgtcag cagtattcct tttcatgttt
     4501 gccggttata aagctgttca ttgtgaactt tgtaactctg ctgtccactt ctaattaaat
     4561 tatcagatgc taaccgtggt ttcctttgaa tgctcccatt catgaaatca agacaatatt
     4621 ggcttcttcc tgtattgggg ttttagttta aacatgaata aatgtcaccc tttggagagc
     4681 tcagtttgtt accagagcct ggttggaaat accagcagac tgttacagat gccaagcagt
     4741 ttttattaag gacaacgtaa caactgatga tatgtgataa agttaaaaaa cttcttatta
     4801 tatattttat ttacaaaagt attatgcaaa gttcgcatta ccttatgaga agaaataaag
     4861 tcaattgata gtt
//
