LOCUS       NM_138838               2981 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus POU class 3 homeobox 1 (Pou3f1), mRNA.
ACCESSION   NM_138838
VERSION     NM_138838.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2981)
  AUTHORS   Iwafuchi-Doi,M., Matsuda,K., Murakami,K., Niwa,H., Tesar,P.J.,
            Aruga,J., Matsuo,I. and Kondoh,H.
  TITLE     Transcriptional regulatory networks in epiblast cells and during
            anterior neural plate development as modeled in epiblast stem cells
  JOURNAL   Development 139 (21), 3926-3937 (2012)
   PUBMED   22992956
  REMARK    Erratum:[Development. 2012 Dec;139(24):4675]
REFERENCE   2  (bases 1 to 2981)
  AUTHORS   Jagalur,N.B., Ghazvini,M., Mandemakers,W., Driegen,S., Maas,A.,
            Jones,E.A., Jaegle,M., Grosveld,F., Svaren,J. and Meijer,D.
  TITLE     Functional dissection of the Oct6 Schwann cell enhancer reveals an
            essential role for dimeric Sox10 binding
  JOURNAL   J Neurosci 31 (23), 8585-8594 (2011)
   PUBMED   21653862
  REMARK    GeneRIF: we propose that Sox10-dependent activation of Oct6 defines
            a feedforward regulatory module that serves to time and amplify the
            onset of myelination in the peripheral nervous system.
REFERENCE   3  (bases 1 to 2981)
  AUTHORS   Wolf,M., Lommes,P., Sock,E., Reiprich,S., Friedrich,R.P.,
            Kriesch,J., Stolt,C.C., Bermingham,J.R. Jr. and Wegner,M.
  TITLE     Replacement of related POU transcription factors leads to severe
            defects in mouse forebrain development
  JOURNAL   Dev Biol 332 (2), 418-428 (2009)
   PUBMED   19527706
REFERENCE   4  (bases 1 to 2981)
  AUTHORS   Hoser,M., Potzner,M.R., Koch,J.M., Bosl,M.R., Wegner,M. and Sock,E.
  TITLE     Sox12 deletion in the mouse reveals nonreciprocal redundancy with
            the related Sox4 and Sox11 transcription factors
  JOURNAL   Mol Cell Biol 28 (15), 4675-4687 (2008)
   PUBMED   18505825
REFERENCE   5  (bases 1 to 2981)
  AUTHORS   Friedrich,R.P., Schlierf,B., Tamm,E.R., Bosl,M.R. and Wegner,M.
  TITLE     The class III POU domain protein Brn-1 can fully replace the
            related Oct-6 during schwann cell development and myelination
  JOURNAL   Mol Cell Biol 25 (5), 1821-1829 (2005)
   PUBMED   15713637
REFERENCE   6  (bases 1 to 2981)
  AUTHORS   Malik,K.F., Jaffe,H., Brady,J. and Young,W.S. 3rd.
  TITLE     The class III POU factor Brn-4 interacts with other class III POU
            factors and the heterogeneous nuclear ribonucleoprotein U
  JOURNAL   Brain Res Mol Brain Res 45 (1), 99-107 (1997)
   PUBMED   9105675
REFERENCE   7  (bases 1 to 2981)
  AUTHORS   Jaegle,M., Mandemakers,W., Broos,L., Zwart,R., Karis,A., Visser,P.,
            Grosveld,F. and Meijer,D.
  TITLE     The POU factor Oct-6 and Schwann cell differentiation
  JOURNAL   Science 273 (5274), 507-510 (1996)
   PUBMED   8662541
REFERENCE   8  (bases 1 to 2981)
  AUTHORS   He,X., Gerrero,R., Simmons,D.M., Park,R.E., Lin,C.J., Swanson,L.W.
            and Rosenfeld,M.G.
  TITLE     Tst-1, a member of the POU domain gene family, binds the promoter
            of the gene encoding the cell surface adhesion molecule P0
  JOURNAL   Mol Cell Biol 11 (3), 1739-1744 (1991)
   PUBMED   1705013
REFERENCE   9  (bases 1 to 2981)
  AUTHORS   Monuki,E.S., Kuhn,R., Weinmaster,G., Trapp,B.D. and Lemke,G.
  TITLE     Expression and activity of the POU transcription factor SCIP
  JOURNAL   Science 249 (4974), 1300-1303 (1990)
   PUBMED   1975954
REFERENCE   10 (bases 1 to 2981)
  AUTHORS   He,X., Treacy,M.N., Simmons,D.M., Ingraham,H.A., Swanson,L.W. and
            Rosenfeld,M.G.
  TITLE     Expression of a large family of POU-domain regulatory genes in
            mammalian brain development
  JOURNAL   Nature 340 (6228), 35-41 (1989)
   PUBMED   2739723
  REMARK    Erratum:[Nature 1989 Aug 24;340(6235):662]
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Nov 27, 2020 this sequence version replaced NM_138838.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: M72711.1, M63712.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2981              JAXUCZ010000005.1  142195090-142198070
FEATURES             Location/Qualifiers
     source          1..2981
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..2981
                     /gene="Pou3f1"
                     /gene_synonym="Oct-6; Otf6; Scip; Testes-1; Tst-1"
                     /note="POU class 3 homeobox 1"
                     /db_xref="GeneID:192110"
                     /db_xref="RGD:619767"
     exon            1..2981
                     /gene="Pou3f1"
                     /gene_synonym="Oct-6; Otf6; Scip; Testes-1; Tst-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             38..1393
                     /gene="Pou3f1"
                     /gene_synonym="Oct-6; Otf6; Scip; Testes-1; Tst-1"
                     /note="POU domain transcription factor SCIP;
                     octamer-binding transcription factor 6; OTF-6;
                     octamer-binding protein 6; octomer-6; suppressed
                     cAMP-inducible POU; octoamer transcription factor-6"
                     /codon_start=1
                     /product="POU domain, class 3, transcription factor 1"
                     /protein_id="NP_620193.1"
                     /db_xref="GeneID:192110"
                     /db_xref="RGD:619767"
                     /translation="MATTAQYLPRGPGGGAGGTGPLMHPDAAAAAAAAAAAERLHAGA
                     AYREVQKLMHHEWLGAGAGHPVGLAHPQWLPTGGGGGGDWAGGPHLEHGKAGGGSTGR
                     ADDGGGGGGFHARLVHQGAAHAGAAWAQGGTAHHLGPAMSPSPGAGGGHQPQPLGLYA
                     QAAYPGGGGGGLAGMLAAGGGGAGPGLHHALHEDGHEAQLEPSPPPHLGAHGHAHGHA
                     HAGGLHAAAAHLHPGAGGGGSSVGEHSDEDAPSSDDLEQFAKQFKQRRIKLGFTQADV
                     GLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEETDSSSGSPTNLDKIA
                     AQGRKRKKRTSIEVGVKGALESHFLKCPKPSAHEITGLADSLQLEKEVVRVWFCNRRQ
                     KEKRMTPAAGAGHPPMDDVYAPGELGPGGGGASPPSAPPPPPPAALHHHHHHTLPGSV
                     Q"
ORIGIN      
        1 ggcggcggcg gcggcgcggc gcagggcgcg gggcggcatg gccaccaccg cgcagtatct
       61 gccgcggggc cccggcggcg gagctggggg caccgggccg ctcatgcatc ccgatgccgc
      121 cgcggcggcg gcagcggcgg cggcggccga gcggctgcac gcgggggccg cgtaccgcga
      181 agtgcagaag ctgatgcacc acgagtggct gggcgcgggc gcgggccacc ccgtgggcct
      241 agcgcaccct caatggctac ccacgggagg aggcggcggc ggcgactggg cgggcggccc
      301 gcacctggaa cacggcaagg caggcggtgg cagtaccggc cgagctgacg acggcggcgg
      361 tggcggaggt ttccacgccc gcttggtgca ccaaggggcg gcccacgcgg gcgcggcatg
      421 ggcacaaggc ggcacagcgc accacttggg ccccgccatg tcgccgtcgc ccggggccgg
      481 cgggggtcac cagccccagc cgctcgggct gtacgctcag gcggcctacc ccggtggcgg
      541 cggcggcggc ctggccggga tgttggcggc gggaggcggc ggcgcgggac ccggcctgca
      601 ccacgcgctg cacgaggacg gccacgaggc acagctggag ccgtcgccac caccgcacct
      661 gggcgcacac ggacacgcac acggacatgc acacgcgggc ggcctgcacg cggcggcggc
      721 gcacctgcac ccaggcgcgg gcggtggtgg ctcgtcggtg ggcgagcact cggacgagga
      781 tgctcccagc tccgacgacc tggagcagtt cgccaagcag ttcaagcaac gacgcatcaa
      841 gctgggcttc acccaggccg acgtggggct agcgctgggc accctctacg gtaatgtgtt
      901 ctcgcagacc accatctgcc gcttcgaggc cctgcagctg agcttcaaga acatgtgcaa
      961 gctcaaaccg ctgctcaaca agtggctgga ggagaccgac tcgtccagcg gcagccccac
     1021 caacctggac aagatcgcgg cgcagggccg caagcgcaag aagcgcacgt ccattgaggt
     1081 gggtgtcaaa ggcgcgctcg agagccactt tctcaagtgt cccaagccgt ctgcgcacga
     1141 gatcaccggc ctggccgaca gcctgcaact ggagaaggag gtggtgcgtg tctggttctg
     1201 caaccggcgg cagaaggaga agcgcatgac ccccgcggcc ggcgcgggcc acccgcccat
     1261 ggacgacgtt tatgcgcctg gggagctggg gcctggcgga ggcggcgcgt cgccaccctc
     1321 tgcgcccccg ccacccccgc cggccgcgct acaccaccac catcaccaca cactacccgg
     1381 ctccgtgcag tgaccctgcg gactgggttc cccgccggcg cagcggtgcc tccggcgcgc
     1441 agccagcgcg cgcggcctgg actctttttg ttgtttattc ggttgctttg gattttacaa
     1501 aaagaaaaaa ggaaaaaaaa aaaagcccag aaacttttaa acaaaaccaa acacccggga
     1561 ccgacccctc tctctggcga gcggcgaaag gcggccgaga ggctgtgttg cccgagccca
     1621 gggagagagc agcgaagatc cagaatgcgc caactcactc tgggcgccct gcgcccactg
     1681 cctgctccct atccccatcc cctcgacgac ccccgcccct gcccccgggc tgttcggggc
     1741 cggatcccgg cagcggcctc cccacagcga aaggtaacgc ggtgcgggat tagggattcc
     1801 ccgggagaat ggacgaaaag aggagagtcc ccagcagctc tcccgggcgc ggactccctg
     1861 tagcctgcag gtcacgggtg gggggctgtc actttattct ttccgcgcct cttctcgcac
     1921 ctggacgcgc cccaccccct caccttttct ccgggcttgg ttttttacgg tttttattta
     1981 ttcgtggagc ctctcggctc ctggggtcct tctaactccg cccgcgccct taatttaaat
     2041 cgctgtatac tgtatttatc ggggccccag aggggaggcc gcgagagccg catctgtgta
     2101 taaaagcagg aaatagccaa agctttaatc tagcctaatt tattttccct ttctcttccc
     2161 ctctcctcct tcaagaacgc aaaacaaaaa caaaaaaaaa ctaacaaaaa aaattttttt
     2221 gagtgttcat ttttcgtttc gttttaccag agccctcggc tcggttcctg gcctagcaga
     2281 gagggtctgc gctcccacgc acacccgggt gggaaggggc atcttcaccc gcaagatcga
     2341 gcgcgcaccg cgggccactg cttccccgcc gggccctgcc cctcctggcc ttaacgaacg
     2401 aaacttggaa aagttggaac tattttttaa ctagctgtag aaataaaccg ttcccccaag
     2461 aaccttccgc ctgtttccct accgcttccc cctgctctct ttccagcccc cgcgggatgc
     2521 aaggatgctg ggggaaccct ggggagaaac tctccaaatt tggggtgagg tgggaaccat
     2581 gtaaatatgt gagatatgta cacaatggcg ggggggaaga aacactttgt gcttggtttt
     2641 tattttttgg ctttctgggt tgttctccct ccccacccta aagggttttg tatgcccgac
     2701 taaaccgaaa aagatatttt aatatggttt cctaatttct gacccatctc tatttatttt
     2761 ctggatgtgt ttggagcttc cccccttcac catttcttca tctgtttctt aaggtttgag
     2821 cgtaattttt ttttaaattt tttgttattc tcagaaaaat gttttggtcc attctctttg
     2881 tatctttatt gcaaaaaata ataataatgt agactgggaa gttcccttta tatttatgtt
     2941 atagtaaata ttttattact cacataaaca tgtaccccag g
//
