LOCUS       NM_199113               2243 bp    mRNA    linear   ROD 19-NOV-2024
DEFINITION  Rattus norvegicus popeye domain cAMP effector 2 (Popdc2), mRNA.
ACCESSION   NM_199113 XM_340990
VERSION     NM_199113.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2243)
  AUTHORS   Holt,I., Fuller,H.R., Schindler,R.F.R., Shirran,S.L., Brand,T. and
            Morris,G.E.
  TITLE     An interaction of heart disease-associated proteins POPDC1/2 with
            XIRP1 in transverse tubules and intercalated discs
  JOURNAL   BMC Mol Cell Biol 21 (1), 88 (2020)
   PUBMED   33261556
  REMARK    GeneRIF: An interaction of heart disease-associated proteins
            POPDC1/2 with XIRP1 in transverse tubules and intercalated discs.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2243)
  AUTHORS   Schindler,R.F., Scotton,C., Zhang,J., Passarelli,C.,
            Ortiz-Bonnin,B., Simrick,S., Schwerte,T., Poon,K.L., Fang,M.,
            Rinne,S., Froese,A., Nikolaev,V.O., Grunert,C., Muller,T.,
            Tasca,G., Sarathchandra,P., Drago,F., Dallapiccola,B., Rapezzi,C.,
            Arbustini,E., Di Raimo,F.R., Neri,M., Selvatici,R., Gualandi,F.,
            Fattori,F., Pietrangelo,A., Li,W., Jiang,H., Xu,X., Bertini,E.,
            Decher,N., Wang,J., Brand,T. and Ferlini,A.
  TITLE     POPDC1(S201F) causes muscular dystrophy and arrhythmia by affecting
            protein trafficking
  JOURNAL   J Clin Invest 126 (1), 239-253 (2016)
   PUBMED   26642364
REFERENCE   3  (bases 1 to 2243)
  AUTHORS   Froese,A., Breher,S.S., Waldeyer,C., Schindler,R.F., Nikolaev,V.O.,
            Rinne,S., Wischmeyer,E., Schlueter,J., Becher,J., Simrick,S.,
            Vauti,F., Kuhtz,J., Meister,P., Kreissl,S., Torlopp,A.,
            Liebig,S.K., Laakmann,S., Muller,T.D., Neumann,J., Stieber,J.,
            Ludwig,A., Maier,S.K., Decher,N., Arnold,H.H., Kirchhof,P.,
            Fabritz,L. and Brand,T.
  TITLE     Popeye domain containing proteins are essential for stress-mediated
            modulation of cardiac pacemaking in mice
  JOURNAL   J Clin Invest 122 (3), 1119-1130 (2012)
   PUBMED   22354168
REFERENCE   4  (bases 1 to 2243)
  AUTHORS   Parnes,D., Jacoby,V., Sharabi,A., Schlesinger,H., Brand,T. and
            Kessler-Icekson,G.
  TITLE     The Popdc gene family in the rat: molecular cloning,
            characterization and expression analysis in the heart and cultured
            cardiomyocytes
  JOURNAL   Biochim Biophys Acta 1769 (9-10), 586-592 (2007)
   PUBMED   17662479
REFERENCE   5  (bases 1 to 2243)
  AUTHORS   Andree,B., Hillemann,T., Kessler-Icekson,G., Schmitt-John,T.,
            Jockusch,H., Arnold,H.H. and Brand,T.
  TITLE     Isolation and characterization of the novel popeye gene family
            expressed in skeletal muscle and heart
  JOURNAL   Dev Biol 223 (2), 371-382 (2000)
   PUBMED   10882522
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC061876.1.
            
            On Jan 1, 2004 this sequence version replaced XM_340990.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC061876.1, AY490241.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760494, SAMN06621351
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2243
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q21"
     gene            1..2243
                     /gene="Popdc2"
                     /note="popeye domain cAMP effector 2"
                     /db_xref="GeneID:360718"
                     /db_xref="RGD:735226"
     exon            1..916
                     /gene="Popdc2"
                     /inference="alignment:Splign:2.1.0"
     CDS             426..1532
                     /gene="Popdc2"
                     /note="popeye domain-containing protein 2-like; popeye
                     domain containing 2"
                     /codon_start=1
                     /product="popeye domain-containing protein 2"
                     /protein_id="NP_954544.1"
                     /db_xref="GeneID:360718"
                     /db_xref="RGD:735226"
                     /translation="MSANGSTVAQLLWQRPVCSGWKPDVEGAVYHLANCFLLMGFMAG
                     SGVYGCFYLFGILGPGYLCLVLWGWLDACGLDIVLWNVLLTVACLLQMAHLVYRVRVN
                     TLPEEFDLLYKTLCLPLQVPLQAYKEIVHCCHEQVLTLATEQTYAVEGETPINRLSLL
                     LSGRVRVSQDGQFLHYIFPYQFMDSPEWESLQPSEEGTFQVTLTAETECSYISWPRKN
                     LHLLLNRERYISRLFSALLGYDISEKLYTLNDKLFAKFGLRFDIRLPSLYHVLSPSAS
                     DGAPESEKEDEETLEAAVSPAQARPICILPTPSCSPPPATTNFPVPLPRARMSRPDSG
                     TLGEDSTSLVLEDFEEVSGSESFMDYRSDGEYMR"
     exon            917..1025
                     /gene="Popdc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1026..1575
                     /gene="Popdc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1576..2225
                     /gene="Popdc2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctgcccggga cgacggagag caggatgtgg ctgcttcgcc ctatgttgct gaagttcgtg
       61 gtgtccagtt cctaccttct ctcaggacat tgtatgcttt ttgctaagaa ctaactatga
      121 agagtatcct aagaaagccg gagccaaaga catttaccag agcactacgg ggggaacaag
      181 agctttgctg agaaagagag aggaaggaag aaggaaaaga aaattccaaa cagcaaactt
      241 aggttttcaa gcttccatga agtgtactat gtcctggcat tttttctcag agccaccgga
      301 agcattcctg ccagcaaagg tggtgagaag ccacttggga atacagatta actgattttt
      361 tttttacccc agtttccttt gtggagacca tatcagagcc tgcaaaggcc ccgagagccc
      421 ccaagatgag tgccaatggc agcacggtgg ctcagctcct ctggcagcgg cctgtgtgca
      481 gtggctggaa accggatgtg gagggggctg tctaccacct ggccaactgc ttcttgctta
      541 tgggctttat ggcaggcagt ggagtatacg gatgcttcta ccttttcggc atcctgggcc
      601 caggctacct ctgcctcgtg ctgtggggct ggcttgatgc ttgtgggcta gacatcgtcc
      661 tttggaacgt cctcctgaca gtggcttgcc tgcttcagat ggcgcacctg gtatatcgcg
      721 ttcgggtgaa taccctcccg gaggagttcg acctcctcta caagacactg tgcctgcccc
      781 tgcaggtacc cctgcaggcc tacaaggaaa ttgtccactg ttgccatgag caggtcttga
      841 cactggccac agagcagacc tacgctgtgg agggtgagac acccatcaac cgcctgtccc
      901 tgctcctctc aggccgggtt cgagtgagcc aggatgggca gtttctacac tacatcttcc
      961 cataccagtt catggactct cctgaatggg aatccctgca gccttctgag gaggggacct
     1021 tccaggtgac gctgaccgct gagactgaat gtagctacat ttcctggccc cggaaaaatc
     1081 ttcaccttct tttgaaccga gagcgataca tctcccgcct tttctcagcc ctgctgggct
     1141 atgacatctc cgagaaactc tataccctca atgacaagct gtttgccaag tttgggttac
     1201 gcttcgacat ccgccttccc agcctttacc atgtcctgag tccctcagcc tctgatgggg
     1261 caccagagtc tgagaaagag gatgaagaaa ccctggaggc agctgtgtcc cctgctcagg
     1321 cccggcccat ctgcatcttg ccaacaccct cttgttcccc acctccagct accaccaact
     1381 tccctgtgcc tctgccccgg gccaggatgt ccaggcctga cagcggcacc ctgggtgagg
     1441 actccaccag cctggtgctg gaggactttg aggaggtttc gggatcagag tcatttatgg
     1501 attataggag cgatggggag tacatgaggt gagggcagaa ctaacacggg cacagacgcc
     1561 gtctccggat cctgtcttct agaagtcctc tccagaactc ttctcaagtt ctgtccagag
     1621 cacaggctcc cttgggtcca ccccacactc ctgaactcta aggatcacag agctgctgtc
     1681 cctgcggcca gatggcgctc ttccacgtcc cctggatgac ctctcctctc cgccctccag
     1741 aaagatctgg gacaagattg gggatggaca tgacatggag aaactcagct tcataagcct
     1801 tcctctcagg aggagggtct agaggcactg ggcctgactc catgttttat gggttgcagg
     1861 acatcgccag gtttacatag cctctgagcc tggtctgtca agcacggcta tgaactcacg
     1921 tcacagggtt gcgaggttcc agtgagctga ttgggtaacg cacttatgac aggacatggc
     1981 atccagcaag cacacattaa aacacttcac gcctcctctc cctatgttgt tgctgtaaaa
     2041 attgtctgaa aggatcaatg acttttacct gtggttattt tattcccaaa gttaagtttc
     2101 aatttagaaa gtagaaaatt ttaaatccca attgttccct tcaactttta atttcaaaac
     2161 acaagtaact gtgtgtgtcc tgttcgtgat tctaacatta aattttagtt ctcaaaggga
     2221 ttttaaaaaa aaaaaaaaaa aaa
//
