LOCUS       NP_954544                368 aa            linear   ROD 19-NOV-2024
DEFINITION  popeye domain-containing protein 2 [Rattus norvegicus].
ACCESSION   NP_954544 XP_340991
VERSION     NP_954544.1
DBSOURCE    REFSEQ: accession NM_199113.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 368)
  AUTHORS   Holt,I., Fuller,H.R., Schindler,R.F.R., Shirran,S.L., Brand,T. and
            Morris,G.E.
  TITLE     An interaction of heart disease-associated proteins POPDC1/2 with
            XIRP1 in transverse tubules and intercalated discs
  JOURNAL   BMC Mol Cell Biol 21 (1), 88 (2020)
   PUBMED   33261556
  REMARK    GeneRIF: An interaction of heart disease-associated proteins
            POPDC1/2 with XIRP1 in transverse tubules and intercalated discs.
            Publication Status: Online-Only
REFERENCE   2  (residues 1 to 368)
  AUTHORS   Schindler,R.F., Scotton,C., Zhang,J., Passarelli,C.,
            Ortiz-Bonnin,B., Simrick,S., Schwerte,T., Poon,K.L., Fang,M.,
            Rinne,S., Froese,A., Nikolaev,V.O., Grunert,C., Muller,T.,
            Tasca,G., Sarathchandra,P., Drago,F., Dallapiccola,B., Rapezzi,C.,
            Arbustini,E., Di Raimo,F.R., Neri,M., Selvatici,R., Gualandi,F.,
            Fattori,F., Pietrangelo,A., Li,W., Jiang,H., Xu,X., Bertini,E.,
            Decher,N., Wang,J., Brand,T. and Ferlini,A.
  TITLE     POPDC1(S201F) causes muscular dystrophy and arrhythmia by affecting
            protein trafficking
  JOURNAL   J Clin Invest 126 (1), 239-253 (2016)
   PUBMED   26642364
REFERENCE   3  (residues 1 to 368)
  AUTHORS   Froese,A., Breher,S.S., Waldeyer,C., Schindler,R.F., Nikolaev,V.O.,
            Rinne,S., Wischmeyer,E., Schlueter,J., Becher,J., Simrick,S.,
            Vauti,F., Kuhtz,J., Meister,P., Kreissl,S., Torlopp,A.,
            Liebig,S.K., Laakmann,S., Muller,T.D., Neumann,J., Stieber,J.,
            Ludwig,A., Maier,S.K., Decher,N., Arnold,H.H., Kirchhof,P.,
            Fabritz,L. and Brand,T.
  TITLE     Popeye domain containing proteins are essential for stress-mediated
            modulation of cardiac pacemaking in mice
  JOURNAL   J Clin Invest 122 (3), 1119-1130 (2012)
   PUBMED   22354168
REFERENCE   4  (residues 1 to 368)
  AUTHORS   Parnes,D., Jacoby,V., Sharabi,A., Schlesinger,H., Brand,T. and
            Kessler-Icekson,G.
  TITLE     The Popdc gene family in the rat: molecular cloning,
            characterization and expression analysis in the heart and cultured
            cardiomyocytes
  JOURNAL   Biochim Biophys Acta 1769 (9-10), 586-592 (2007)
   PUBMED   17662479
REFERENCE   5  (residues 1 to 368)
  AUTHORS   Andree,B., Hillemann,T., Kessler-Icekson,G., Schmitt-John,T.,
            Jockusch,H., Arnold,H.H. and Brand,T.
  TITLE     Isolation and characterization of the novel popeye gene family
            expressed in skeletal muscle and heart
  JOURNAL   Dev Biol 223 (2), 371-382 (2000)
   PUBMED   10882522
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC061876.1.
            
            On Jan 1, 2004 this sequence version replaced XP_340991.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC061876.1, AY490241.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760494, SAMN06621351
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q21"
     Protein         1..368
                     /product="popeye domain-containing protein 2"
                     /note="popeye domain-containing protein 2-like; popeye
                     domain containing 2"
                     /calculated_mol_wt=41211
     Region          26..251
                     /region_name="Popeye"
                     /note="Popeye protein conserved region; pfam04831"
                     /db_xref="CDD:461448"
     CDS             1..368
                     /gene="Popdc2"
                     /coded_by="NM_199113.1:426..1532"
                     /db_xref="GeneID:360718"
                     /db_xref="RGD:735226"
ORIGIN      
        1 msangstvaq llwqrpvcsg wkpdvegavy hlancfllmg fmagsgvygc fylfgilgpg
       61 ylclvlwgwl dacgldivlw nvlltvacll qmahlvyrvr vntlpeefdl lyktlclplq
      121 vplqaykeiv hccheqvltl ateqtyaveg etpinrlsll lsgrvrvsqd gqflhyifpy
      181 qfmdspewes lqpseegtfq vtltaetecs yiswprknlh lllnreryis rlfsallgyd
      241 iseklytlnd klfakfglrf dirlpslyhv lspsasdgap esekedeetl eaavspaqar
      301 picilptpsc spppattnfp vplprarmsr pdsgtlgeds tslvledfee vsgsesfmdy
      361 rsdgeymr
//
