LOCUS       NM_001009437            1743 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus protein O-linked mannose
            N-acetylglucosaminyltransferase 2 (beta 1,4-) (Pomgnt2), mRNA.
ACCESSION   NM_001009437 XM_236725
VERSION     NM_001009437.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1743)
  AUTHORS   Endo,Y., Dong,M., Noguchi,S., Ogawa,M., Hayashi,Y.K., Kuru,S.,
            Sugiyama,K., Nagai,S., Ozasa,S., Nonaka,I. and Nishino,I.
  TITLE     Milder forms of muscular dystrophy associated with POMGNT2
            mutations
  JOURNAL   Neurol Genet 1 (4), e33 (2015)
   PUBMED   27066570
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1743)
  AUTHORS   Nakagawa,N., Yagi,H., Kato,K., Takematsu,H. and Oka,S.
  TITLE     Ectopic clustering of Cajal-Retzius and subplate cells is an
            initial pathological feature in Pomgnt2-knockout mice, a model of
            dystroglycanopathy
  JOURNAL   Sci Rep 5, 11163 (2015)
   PUBMED   26060116
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1743)
  AUTHORS   Yagi,H., Nakagawa,N., Saito,T., Kiyonari,H., Abe,T., Toda,T.,
            Wu,S.W., Khoo,K.H., Oka,S. and Kato,K.
  TITLE     AGO61-dependent GlcNAc modification primes the formation of
            functional glycans on alpha-dystroglycan
  JOURNAL   Sci Rep 3, 3288 (2013)
   PUBMED   24256719
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1743)
  AUTHORS   Yoshida-Moriguchi,T., Willer,T., Anderson,M.E., Venzke,D.,
            Whyte,T., Muntoni,F., Lee,H., Nelson,S.F., Yu,L. and Campbell,K.P.
  TITLE     SGK196 is a glycosylation-specific O-mannose kinase required for
            dystroglycan function
  JOURNAL   Science 341 (6148), 896-899 (2013)
   PUBMED   23929950
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AJ868534.1.
            
            [WARNING] On Oct 10, 2024 this sequence was replaced by
            NM_001009437.2.
            
            On Jan 12, 2005 this sequence version replaced XM_236725.2.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AJ868534.1 [ECO:0000345]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1743
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="W"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q32"
     gene            1..1743
                     /gene="Pomgnt2"
                     /gene_synonym="Ago61; Gtdc2; RGD1304827"
                     /note="protein O-linked mannose
                     N-acetylglucosaminyltransferase 2 (beta 1,4-)"
                     /db_xref="GeneID:316091"
                     /db_xref="RGD:1304827"
     CDS             1..1743
                     /gene="Pomgnt2"
                     /gene_synonym="Ago61; Gtdc2; RGD1304827"
                     /EC_number="2.4.1.312"
                     /function="contributes to the synthesis of
                     glycoconjugates"
                     /note="glycosyltransferase; glycosyltransferase-like
                     domain-containing protein 2; glycosyltransferase-like
                     domain containing 2"
                     /codon_start=1
                     /product="protein O-linked-mannose
                     beta-1,4-N-acetylglucosaminyltransferase 2"
                     /protein_id="NP_001009437.1"
                     /db_xref="GeneID:316091"
                     /db_xref="RGD:1304827"
                     /translation="MHLSAVFNALLVSVLAAVLWKHVRLREHAATLEEELALGQQSLD
                     PVPGLRIDYPKALQILMEGGTHMVCTGRTHTDRICRFKWLCYSNEAEEFIFFHGNSSV
                     MLPNLGSRRFQPALLDLSTVEDHNAQYFNFVELPAAALRFMPKPVFVPDVALIANRFN
                     PDNLMHVFHDDLLPLFYTLRQFPGLAQEARLFFMEGWGEGAHFDLYKLLSPKQPLLRS
                     QLKTLGRLLCFSHAFVGLSKVTTWYQYGFVQPQGPKANILVSGNEIRQFTRFMTERLN
                     VSHAGAPLGEEYILVFSRTQNRLILNEAELLLELAQEFQMKTVTVSLEDHTFADVVRL
                     VSNASMLVSMHGAQLVTALFLPRGATVVELFPYAVNPDHYTPYKTLATLPGMDLQYVA
                     WRNMIRENTVTHPERPWDQGGITHLDRAEQARILQSREVPRHLCCRNPEWLFRIYQDT
                     RVDIPSLMQSIRRVVKGRPGPRRQRWAISLYPGKVREARCQASVQGATEARLSVSWQI
                     PWNLKYLKVREVRYEVWLQEQGENTYVPYMLTLQNHTFTENIKPFTTYLVWVRCIFNR
                     SLLGPFADVLVCST"
     exon            1..1743
                     /gene="Pomgnt2"
                     /gene_synonym="Ago61; Gtdc2; RGD1304827"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgcacctct ctgcagtatt caacgccctc ctggtatcag tgctggctgc ggtcctgtgg
       61 aagcacgtgc ggttgcggga gcatgcggcc acgctagagg aggagctggc ccttggacag
      121 cagtccctgg atccagtccc agggctgagg atcgactacc cgaaggccct gcagatcctc
      181 atggagggtg gcacccacat ggtgtgcacg ggccgcaccc acacggaccg catctgccgc
      241 ttcaagtggc tctgctactc caatgaggcc gaagaattca tctttttcca cggcaactcg
      301 tctgtgatgc tgcccaacct gggctcccgg cgcttccagc cggccctgct ggacctgtcc
      361 actgtggagg accataatgc ccagtacttc aacttcgtgg agctgcctgc cgcagccctg
      421 cgcttcatgc caaagccagt gttcgtgcct gatgtggccc tcatcgccaa ccgcttcaac
      481 cccgataacc tcatgcacgt cttccatgat gacctgctcc ccctcttcta cacactgagg
      541 cagttccccg gcctggccca agaggcccgg ctcttcttta tggaggggtg gggcgagggc
      601 gcccactttg acctctataa actcctcagc cccaagcagc cgctgctccg ttcgcagctc
      661 aagaccctgg gccggctgct ctgcttttcc catgctttcg tgggcctgtc caaggtcacc
      721 acctggtacc agtacggctt tgtccagccc cagggcccaa aggccaacat cctggtctct
      781 ggcaatgaga tccggcagtt cacccgcttc atgactgaaa ggctgaacgt gagccacgcg
      841 ggggcgcccc tcggggagga atacattctg gtcttcagcc gcacccagaa tagactcatc
      901 ctgaatgagg cagagctgtt gctggagcta gcacaagagt tccagatgaa gaccgtgaca
      961 gtgtccctgg aggaccacac ctttgccgat gtcgtgcggc tggtcagcaa cgcctccatg
     1021 ttagtcagca tgcatggggc ccagctggtg acagccctct tcctgccccg tggggctact
     1081 gtggttgaac tcttcccgta cgctgtcaat cctgaccact acacccccta taagacgctg
     1141 gccacactgc ctggcatgga cctgcagtat gtagcctgga gaaacatgat ccgggagaac
     1201 acagtcacgc accccgagcg accctgggac caagggggaa tcacccactt ggaccgggct
     1261 gagcaggccc gcatcctaca gagccgagag gttccccggc atctgtgttg ccggaaccca
     1321 gagtggctat tccgaatcta ccaggacacc agggtggaca tcccatccct catgcaatcc
     1381 attcggcgtg tggtgaaggg ccggccgggg ccacggaggc agaggtgggc aatcagcctg
     1441 taccctggta aggtacggga ggctcgatgt caggcgtcgg tgcagggcgc cacggaggcc
     1501 cgcctgtctg tgtcctggca gatcccgtgg aacctcaagt acctgaaagt gagggaggtg
     1561 aggtacgagg tgtggctgca ggagcaaggg gagaacacgt atgtgcctta catgctgacg
     1621 ctgcagaacc ataccttcac ggagaacatc aaacctttta ccacctacct ggtgtgggtc
     1681 cgctgcatct tcaacaggag cctcctggga ccttttgcag atgtgctggt gtgcagcacg
     1741 tag
//
