LOCUS       NM_053622               5506 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus POM121 transmembrane nucleoporin (Pom121), mRNA.
ACCESSION   NM_053622
VERSION     NM_053622.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5506)
  AUTHORS   Talamas,J.A. and Hetzer,M.W.
  TITLE     POM121 and Sun1 play a role in early steps of interphase NPC
            assembly
  JOURNAL   J Cell Biol 194 (1), 27-37 (2011)
   PUBMED   21727197
  REMARK    GeneRIF: The propose a model in which POM121 and Sun1 interact
            transiently to promote early steps of interphase nuclear pore
            complexes assembly.
REFERENCE   2  (bases 1 to 5506)
  AUTHORS   Kihlmark,M., Rustum,C., Eriksson,C., Beckman,M., Iverfeldt,K. and
            Hallberg,E.
  TITLE     Correlation between nucleocytoplasmic transport and
            caspase-3-dependent dismantling of nuclear pores during apoptosis
  JOURNAL   Exp Cell Res 293 (2), 346-356 (2004)
   PUBMED   14729472
REFERENCE   3  (bases 1 to 5506)
  AUTHORS   Daigle,N., Beaudouin,J., Hartnell,L., Imreh,G., Hallberg,E.,
            Lippincott-Schwartz,J. and Ellenberg,J.
  TITLE     Nuclear pore complexes form immobile networks and have a very low
            turnover in live mammalian cells
  JOURNAL   J Cell Biol 154 (1), 71-84 (2001)
   PUBMED   11448991
REFERENCE   4  (bases 1 to 5506)
  AUTHORS   Hallberg,E., Wozniak,R.W. and Blobel,G.
  TITLE     An integral membrane protein of the pore membrane domain of the
            nuclear envelope contains a nucleoporin-like region
  JOURNAL   J Cell Biol 122 (3), 513-521 (1993)
   PUBMED   8335683
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000012.1.
            
            On Nov 26, 2020 this sequence version replaced NM_053622.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: Z21513.1, SRR26643429.42854.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-574               JAXUCZ010000012.1  26913513-26914086
            575-790             JAXUCZ010000012.1  26915398-26915613
            791-949             JAXUCZ010000012.1  26916154-26916312
            950-1030            JAXUCZ010000012.1  26918979-26919059
            1031-1202           JAXUCZ010000012.1  26920433-26920604
            1203-1294           JAXUCZ010000012.1  26921815-26921906
            1295-1368           JAXUCZ010000012.1  26922576-26922649
            1369-1493           JAXUCZ010000012.1  26922926-26923050
            1494-1596           JAXUCZ010000012.1  26923155-26923257
            1597-1770           JAXUCZ010000012.1  26923714-26923887
            1771-3384           JAXUCZ010000012.1  26924529-26926142
            3385-3507           JAXUCZ010000012.1  26928267-26928389
            3508-5506           JAXUCZ010000012.1  26928863-26930861
FEATURES             Location/Qualifiers
     source          1..5506
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q12"
     gene            1..5506
                     /gene="Pom121"
                     /note="POM121 transmembrane nucleoporin"
                     /db_xref="GeneID:113975"
                     /db_xref="RGD:620680"
     exon            1..574
                     /gene="Pom121"
                     /inference="alignment:Splign:2.1.0"
     CDS             6..3605
                     /gene="Pom121"
                     /note="P145; pore membrane protein of 121 kDa; nucleoporin
                     Nup121; integral membrane glycoprotein; nuclear pore
                     membrane glycoprotein 121 kD; nuclear pore membrane
                     protein 121; POM121 membrane glycoprotein"
                     /codon_start=1
                     /product="nuclear envelope pore membrane protein POM 121"
                     /protein_id="NP_446074.2"
                     /db_xref="GeneID:113975"
                     /db_xref="RGD:620680"
                     /translation="MSPAAAAADGGERRRPPLGVREGRGRTRGCGGPAGAAALGLALL
                     GLALYLVPAAAALAWLAVGASAAWWGLSREPRGPRGLSSFVRESRRHPRPALTASPLP
                     AKSPVNGSLCEPRSPLGGPDPAELLLMGSYLGKPGPPEPALPQDPRDRPGRRPPSRSP
                     PSSSTAQRVHHVYPALPTPLLRPSRRPPHRDCGPLSSRFVITPRRRYPIQQAQYSLLG
                     ALPTVCWNGGHKKAVLSARNSRMVCSPVTVRIAPPDSKLFRSPMPEQILSTTLSSPSS
                     NAPDPCAKETVLNALKEKKKRTVAEEDQLHLDGQENKRRRHDSSGSGHSAFEPLVANG
                     VPAAFVPKPGSLKRSLASQSSDDHLNKRSRTSSVSSLTSTCTGGIPSSSRNAITSSYS
                     STRGVSQLWKRSGPTSSPFSSPASSRSQTPERPAKKTREEEPCHQSSSSAPLVTDKES
                     PGEKVTDPATGKQQSLWTSPPTPGSSGQRKRKIQLLPSRRGDQLTLPPPPELGYSITA
                     EDLDMERRASLQWFNKVLEDKTDDASTPATDTSPATSPPFTLTLPTVGPAASPASLPA
                     PSSNPLLESLKKMQESPAPSSSEPPEAATVAAPSPPKTPSLLAPLVSPLTGPLASTSS
                     DSKPTTTFLGLASASSATPLTDTKAPGVSQAQLCVSTPAATAPSPTPASTLFGMLSPP
                     ASSSSLATPGPACASPMFKPIFPATPKSESDNPLPTSSSAATTTPASTALPTTATATA
                     HTFKPIFESVEPFAAMPLSPPFSLKQTTAPATTAATSAPLLTGLGTATSTVATGTTAS
                     ASKPVFGFGVTTAASTASTIASTSQSLLFGGAPPVTASSSAPALASIFQFGKPLAPAA
                     SVAGTSFSQSLASSAQTAASNSSGGFSGFGGTLTTSTSAPATTSQPTLTFSNTVTPTF
                     NIPFSASAKPALPTYPGANSQPTFGATDGATKPALAPSFGSSFTFGNSVASAPSAAPA
                     PAAFGGAAQPAFGGLKASASTFGTPASTQPAFGSTTSVFSFGSATTSGFGAAAATTQT
                     THSGSSSSLFGSSTPSPFTFGGSAAPAGGGGFGLSATPGTGSTSGTFSFGSGQSGTTG
                     TTTSFGGSLSQNTLGAPSQSSPFAFSVGSTPESKPVFGGTSTPTFGQSAPAPGVGTTG
                     SSLSFGAPSTPAQGFVGVGPFGSGAPSFSIGAGSKTPGARQRLQARRQHTRKK"
     exon            575..790
                     /gene="Pom121"
                     /inference="alignment:Splign:2.1.0"
     exon            791..949
                     /gene="Pom121"
                     /inference="alignment:Splign:2.1.0"
     exon            950..1030
                     /gene="Pom121"
                     /inference="alignment:Splign:2.1.0"
     exon            1031..1202
                     /gene="Pom121"
                     /inference="alignment:Splign:2.1.0"
     exon            1203..1294
                     /gene="Pom121"
                     /inference="alignment:Splign:2.1.0"
     exon            1295..1368
                     /gene="Pom121"
                     /inference="alignment:Splign:2.1.0"
     exon            1369..1493
                     /gene="Pom121"
                     /inference="alignment:Splign:2.1.0"
     exon            1494..1596
                     /gene="Pom121"
                     /inference="alignment:Splign:2.1.0"
     exon            1597..1770
                     /gene="Pom121"
                     /inference="alignment:Splign:2.1.0"
     exon            1771..3384
                     /gene="Pom121"
                     /inference="alignment:Splign:2.1.0"
     exon            3385..3507
                     /gene="Pom121"
                     /inference="alignment:Splign:2.1.0"
     exon            3508..5506
                     /gene="Pom121"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccgcgatgtc tccggcggct gcggcggctg acggaggcga gcggcggcgg cctccgttgg
       61 gcgtacggga aggccggggc cggacccgcg gctgcggagg accagcgggt gccgcggcac
      121 tgggcctagc gctgctcggc ctcgcgctct acctagtgcc cgcggcggcc gcgctggcct
      181 ggctggccgt gggggcgagc gcggcctggt ggggcctgag ccgagaaccc cgcggcccga
      241 ggggcctgtc gtcgttcgtg cgcgagtcgc gccgtcaccc gcggcccgcg ctcaccgctt
      301 caccgcttcc agccaagtcg ccagtcaacg gtagcctctg cgaaccccgc agcccgcttg
      361 gaggccccga ccccgctgaa ctcttactca tgggcagcta cctgggcaag ccaggcccgc
      421 cggagcctgc cctcccgcag gaccctagag acaggccagg gcgccgccca ccctcacggt
      481 ccccgccgtc gtcttcgacg gcccagcgag tccaccacgt ctaccccgcg ctccccaccc
      541 cacttttgcg accttctcgg aggccgcccc accgagattg tgggccttta tccagtcggt
      601 ttgttataac accccgaaga cgatatccca ttcagcaagc ccagtattcc ttgctggggg
      661 cacttccaac cgtatgctgg aatggtggcc ataagaaagc cgtgctatct gcacggaact
      721 cgaggatggt gtgcagccca gtgacagtga ggattgcccc tccagatagc aagctatttc
      781 gatcaccaat gccggagcag atactcagca ccacactgtc ttcaccatca agtaatgccc
      841 cagacccttg tgcaaaggag acggtgctga atgccctcaa ggaaaagaag aaaaggacag
      901 tggcagagga agaccagctg catcttgatg gccaggaaaa caagagaaga cgccacgata
      961 gcagtgggag tggacattcg gcattcgagc cccttgtggc caacggagtc cctgctgcat
     1021 ttgtgcctaa gcctggctcc ctgaagagaa gtctggcttc ccagagctcg gatgaccact
     1081 tgaacaaacg gtctcgcacc tcctctgtga gctccctgac tagcacatgc acaggaggca
     1141 tccccagctc cagccgcaac gccatcacca gctcctacag ctccacccga ggtgtctcac
     1201 agctgtggaa gaggagtggt cccacctctt ctcccttctc cagcccagct tcctcccgct
     1261 cccagacacc agagaggcca gccaagaaga caagagagga ggaaccatgt caccagtcca
     1321 gttcttcagc tcccttggtg acagacaagg agtccccagg agaaaaggtt acagatccag
     1381 ccacggggaa gcagcagagc ctgtggactt ccccacccac acctggcagc tccgggcaac
     1441 gcaaacgcaa gattcagctg ctgccctccc ggcgagggga ccagctcacc ttgcctccac
     1501 cccctgagct tggctattcc atcactgctg aagacctgga catggagagg agagcctcac
     1561 tgcagtggtt taacaaggtc ttggaggata agacggatga tgcctctacc ccagccactg
     1621 acacctcccc agccaccagc cctcccttca cactcaccct gcctaccgtg gggcctgctg
     1681 cctcaccagc ctccctccca gctcccagct ctaacccact gttggagagt ttgaagaaga
     1741 tgcaggagtc tccagcccca tcctcctcag aacctcctga ggcagcaaca gttgcggccc
     1801 cttcacctcc gaagacacct agcctcctgg cccctcttgt ctcaccactg acagggcccc
     1861 tagccagcac ctcctcagac tccaaaccta caaccacctt cctggggctg gcttctgctt
     1921 catccgccac accactcact gacaccaagg cccctggagt ctctcaggcc cagctgtgtg
     1981 tcagcacccc agccgccaca gctccctccc caactccagc cagcacgctg ttcgggatgc
     2041 tgagtccacc tgccagctcc tcttcccttg ccactcctgg cccagcttgc gcttctccca
     2101 tgtttaagcc cattttcccg gccacaccta agagtgagag tgataatccc ttgccaacta
     2161 gctcctcagc cgccacgaca actccagcca gcaccgccct ccccacaaca gcaaccgcca
     2221 cagctcacac tttcaagccc atttttgaga gcgtggagcc atttgcagcc atgcccctgt
     2281 cacctccctt ctccctgaag cagacaactg ctccggccac cactgcagcc acatcagctc
     2341 ctctcctcac tggcctgggc actgccactt ccacagtggc cactggcacc acagcttctg
     2401 cctccaagcc tgtgtttggc tttggagtga ccactgcagc gagcactgcc agtaccatag
     2461 cttccacctc ccagtcactt ctgtttgggg gagccccgcc tgttactgct tccagttccg
     2521 ccccagccct ggcctccatc ttccaatttg gcaagcccct tgccccagca gcgtctgtgg
     2581 cgggcacctc ctttagccag tcccttgcca gctctgccca gactgctgcc agcaatagta
     2641 gtgggggctt cagtggtttt ggtgggaccc tcaccacctc cacctctgcc cctgccacca
     2701 ccagccagcc cactctgacc ttcagcaaca ctgtcacccc caccttcaac attcccttta
     2761 gcgccagtgc caagcctgcg ctcccaacct accccggagc caactcacag cccacatttg
     2821 gagccactga tggggccacc aagccggcac ttgccccaag ttttggcagc tctttcactt
     2881 ttggcaactc tgtggcctca gccccgtcgg cagccccagc accagccgcc tttggtggtg
     2941 ctgcacagcc agctttcgga gggttgaaag cctcagcctc caccttcggc acccctgcca
     3001 gcactcagcc ggctttcggt agcaccactt ccgtgttctc ctttggttca gccaccacat
     3061 ctggctttgg tgctgctgcc gccaccacac agaccaccca cagtgggagc agcagctctc
     3121 tgtttggcag ctctactcca tccccattca cattcggtgg ctcagcagct cctgctggtg
     3181 gtggaggctt tgggcttagt gctacaccag gtaccggctc cacctctgga acttttagct
     3241 ttggatctgg acagagcggg accacgggca ccaccacctc ctttggggga agtctgagtc
     3301 agaacaccct gggcgcacct agccagagct caccgttcgc cttcagtgtg ggcagtacac
     3361 ctgaaagcaa gcctgtgttt ggaggcacat ccacacctac ttttgggcag agtgcccctg
     3421 ccccaggagt cggcaccaca ggcagcagcc tctcatttgg ggccccttca acacctgccc
     3481 aaggctttgt tggagttgga cctttcggat caggagcccc ttccttttcc attggcgcgg
     3541 gatccaagac cccaggggct cgacagcgac ttcaggcccg aaggcagcac acccgcaaga
     3601 agtagcctgc ctgcctgcct gcctgcaccc ccacccctgc ctggacctgg acctcagcac
     3661 ctgctaggaa gagcctctga ccctgcaaat cccatagcaa acccagccgt caccagggtg
     3721 gaagtctggc cctttctgtt ctagaggaag cgagtgcccc ggggaggggc agtttacttg
     3781 aacagtcaca ctggttaggc tggagaactg aaaaaaaaca tctgtacata ttgtcctctt
     3841 gctgccccag cgcttgttta gtgtataacc taggcagccc ccctctcctt gggcaccatt
     3901 ctgctggcac ccacttggat ccctaataca tgaggtggga ttgggggaaa cggaatgtcc
     3961 ctagctttgc ctgcttggct tggccatgag tggttctctt cctctgatcc cctcagggtc
     4021 tctccctatt tcttgctgct ttgtccttca ccggtcctct gtgagattca ttccttttaa
     4081 atggcggtga atcttgcttt gccttggaga ccccagtggg cgctgttttg cctcttctgt
     4141 caagtctgtt tagtctccag ccctctgcta acccagcctc tcaaaaggtt ggtggctcaa
     4201 gactgttagc ctggcagagc cagggagaag tctgctccag gaggtcctgg ggcaggcaga
     4261 ccagaccgcc ccccactgct tctagctgcc tcttcacctg cccgccaccc cacgggccaa
     4321 cttgcctctt tgggattgta ttttccaagc cttgtactgt gtttgtctga tgttaatgtg
     4381 tgttgctcct tgaatcgagt ttggaggaag aattgaattg tatgtgtggc ggcatgttgg
     4441 taatgccgga cttaatgtca cctgggcctc ctgggcctag ctaattgaat gctgaagtgg
     4501 caccgccaca gtgacagcca cagtgctgac tcctgaatct caatagtgtt tgactaaggg
     4561 ctggcagccc aggggatgga tggagccggc tgggagcaga cttccctctc tgttggtcct
     4621 ccccatacag cccaccccag gccagggcgg cttctgcctg tgcttggagc tgtagataac
     4681 caactacact ttgagttctt agttgtattt ccaaaagggt cctacctagc ctgtctctcc
     4741 ttccaaagcc acaccacacc cttaggccca agcctggctg ccatgtccgc cctctttggg
     4801 agaagtatga atgcgtgtgt ctaaattaaa agaaaaaata tttaaacatt ttttaacaaa
     4861 ataaaaattt atttttgtat ttaagctaaa ttgcctttta aattccttca agcttggttc
     4921 actgaggtgg ttaagtataa atgctatgga atagtaggaa ttagctgtat agttatgcct
     4981 gtgtgaagga agggctcata gctgtcccca gcagctctcc tgagggggca gagctccttc
     5041 tagacatgtc gtgtaagtgt aactcttatt ttataaacag tgtgatgtag ctgtaactgg
     5101 tcccctttcc ttgtgagtgg gattgaatgt tttatggcag gggttaggct gggttgtatg
     5161 gaactggaga agagctggac ctcaagtccc aaatgcctgt gaggatgggg atgggtgggg
     5221 gtctgaacac gaagcctcta cctgtgcctc aggtaaggaa gggcctccct ccaattcagt
     5281 ctgagctaat tacctcagct ccacagcagg cctgtatcca gggtgccgga agaggtgtcc
     5341 tggaatagcc tcggtgtgtg agcacatctg tccgtgctca cgctggacag ggacagggag
     5401 gctggggctt ccaccacaga ctgcgtttct gtgagtgtag ctgagatttt tagtatgaat
     5461 gtgagattgt tcttgcttat gtcattaaaa ataaaactgt gatctg
//
