LOCUS       NM_001012081            2413 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus RNA polymerase III subunit C (Polr3c), transcript
            variant 1, mRNA.
ACCESSION   NM_001012081 XM_227471
VERSION     NM_001012081.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2413)
  AUTHORS   Renaud,M., Praz,V., Vieu,E., Florens,L., Washburn,M.P., l'Hote,P.
            and Hernandez,N.
  TITLE     Gene duplication and neofunctionalization: POLR3G and POLR3GL
  JOURNAL   Genome Res 24 (1), 37-51 (2014)
   PUBMED   24107381
REFERENCE   2  (bases 1 to 2413)
  AUTHORS   Lefevre,S., Dumay-Odelot,H., El-Ayoubi,L., Budd,A., Legrand,P.,
            Pinaud,N., Teichmann,M. and Fribourg,S.
  TITLE     Structure-function analysis of hRPC62 provides insights into RNA
            polymerase III transcription initiation
  JOURNAL   Nat Struct Mol Biol 18 (3), 352-358 (2011)
   PUBMED   21358628
  REMARK    Erratum:[Nat Struct Mol Biol. 2011 Apr;18(4):516]
REFERENCE   3  (bases 1 to 2413)
  AUTHORS   Dumay-Odelot,H., Durrieu-Gaillard,S., Da Silva,D., Roeder,R.G. and
            Teichmann,M.
  TITLE     Cell growth- and differentiation-dependent regulation of RNA
            polymerase III transcription
  JOURNAL   Cell Cycle 9 (18), 3687-3699 (2010)
   PUBMED   20890107
  REMARK    Review article
REFERENCE   4  (bases 1 to 2413)
  AUTHORS   Ablasser,A., Bauernfeind,F., Hartmann,G., Latz,E., Fitzgerald,K.A.
            and Hornung,V.
  TITLE     RIG-I-dependent sensing of poly(dA:dT) through the induction of an
            RNA polymerase III-transcribed RNA intermediate
  JOURNAL   Nat Immunol 10 (10), 1065-1072 (2009)
   PUBMED   19609254
REFERENCE   5  (bases 1 to 2413)
  AUTHORS   Hu,P., Wu,S., Sun,Y., Yuan,C.C., Kobayashi,R., Myers,M.P. and
            Hernandez,N.
  TITLE     Characterization of human RNA polymerase III identifies orthologues
            for Saccharomyces cerevisiae RNA polymerase III subunits
  JOURNAL   Mol Cell Biol 22 (22), 8044-8055 (2002)
   PUBMED   12391170
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Dec 20, 2022 this sequence version replaced NM_001012081.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083667.1, SRR26360172.900531.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-386               JAXUCZ010000002.1  186950577-186950962 c
            387-552             JAXUCZ010000002.1  186949277-186949442 c
            553-808             JAXUCZ010000002.1  186947295-186947550 c
            809-994             JAXUCZ010000002.1  186947011-186947196 c
            995-1080            JAXUCZ010000002.1  186945625-186945710 c
            1081-1185           JAXUCZ010000002.1  186942558-186942662 c
            1186-1278           JAXUCZ010000002.1  186942329-186942421 c
            1279-1359           JAXUCZ010000002.1  186940479-186940559 c
            1360-1411           JAXUCZ010000002.1  186940247-186940298 c
            1412-1472           JAXUCZ010000002.1  186939400-186939460 c
            1473-1623           JAXUCZ010000002.1  186938905-186939055 c
            1624-1725           JAXUCZ010000002.1  186937986-186938087 c
            1726-1775           JAXUCZ010000002.1  186937820-186937869 c
            1776-1925           JAXUCZ010000002.1  186937140-186937289 c
            1926-2413           JAXUCZ010000002.1  186935038-186935525 c
FEATURES             Location/Qualifiers
     source          1..2413
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..2413
                     /gene="Polr3c"
                     /note="RNA polymerase III subunit C"
                     /db_xref="GeneID:310685"
                     /db_xref="RGD:1311545"
     exon            1..386
                     /gene="Polr3c"
                     /inference="alignment:Splign:2.1.0"
     exon            387..552
                     /gene="Polr3c"
                     /inference="alignment:Splign:2.1.0"
     CDS             406..2007
                     /gene="Polr3c"
                     /note="RNA polymerase III subunit C3; DNA-directed RNA
                     polymerase III subunit C; polymerase (RNA) III subunit C;
                     polymerase (RNA) III (DNA directed) polypeptide C"
                     /codon_start=1
                     /product="DNA-directed RNA polymerase III subunit RPC3"
                     /protein_id="NP_001012081.1"
                     /db_xref="GeneID:310685"
                     /db_xref="RGD:1311545"
                     /translation="MTQAEIKLCSLLLQEHFGEIVEKIGVHLIRTGSQPLRVIAHDTK
                     ASLDQVKKALCVLIHHNLVIYHVHKRGVVEYEAQCSRVLRMLRYPRYIYTTKTLYGDT
                     GELIVEELLLNGKMTMSAVVKKVADRLTETMEDGKTMDYAEVSNAFVRLADTHFVQRC
                     PLVPDTDSSDPGPPPPAPNLVINEKDMYLVPKLSLIGKGKRRRSSDEDAAGEPKAKKP
                     RCTDNEEPTPDDGIYWQVNLDRFHQHFRDQAIVSAVANRMDQTSSEIVRTMLRMSEIT
                     TPSGAPFTQPLSSNEIFRSLPVGYNISKQVLDQYLTLLADDPLEFIGKAGDSGGGMYV
                     INLHKALASLSTATLESVIQERFGSRCARIFRLVLQKKHLEQKQVEDFAMIPAKEAKD
                     MLYKMLSENFISLQEIPKTPDHAPSRTFYLYTVNVLSAARMLLHRCYKSIANLIERRQ
                     FETKENKRLLEKSQRVEAIMASMQATGAEEVQLQEIEEMITAPERQQLETLKRNVNKL
                     DASEIQVDETIFLLESYIESTMKRQ"
     exon            553..808
                     /gene="Polr3c"
                     /inference="alignment:Splign:2.1.0"
     exon            809..994
                     /gene="Polr3c"
                     /inference="alignment:Splign:2.1.0"
     exon            995..1080
                     /gene="Polr3c"
                     /inference="alignment:Splign:2.1.0"
     exon            1081..1185
                     /gene="Polr3c"
                     /inference="alignment:Splign:2.1.0"
     exon            1186..1278
                     /gene="Polr3c"
                     /inference="alignment:Splign:2.1.0"
     exon            1279..1359
                     /gene="Polr3c"
                     /inference="alignment:Splign:2.1.0"
     exon            1360..1411
                     /gene="Polr3c"
                     /inference="alignment:Splign:2.1.0"
     exon            1412..1472
                     /gene="Polr3c"
                     /inference="alignment:Splign:2.1.0"
     exon            1473..1623
                     /gene="Polr3c"
                     /inference="alignment:Splign:2.1.0"
     exon            1624..1725
                     /gene="Polr3c"
                     /inference="alignment:Splign:2.1.0"
     exon            1726..1775
                     /gene="Polr3c"
                     /inference="alignment:Splign:2.1.0"
     exon            1776..1925
                     /gene="Polr3c"
                     /inference="alignment:Splign:2.1.0"
     exon            1926..2413
                     /gene="Polr3c"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcatccgcct ggatggtgcg ctacttctaa gaaggggcta tgggctgctc ctgatcttag
       61 gctactgtcc tcgggaggat aacttttgga gcttctaaat tagcactgac cctgaggtta
      121 gtgaaaaagc tgccggaatg aggaggccct gactcagggc taagaaacaa agtccggaac
      181 agaaacttcc atgaaggcaa gaggagccag gcgccttgga aatgttttca aggatggcaa
      241 ctggtctaag gatgtttctc caaagacgtg tggataagtg aaatagtctt ctgtgcgacc
      301 ctgtggcaag agggaaaaaa atttaggttc tgaagagttg aagaaagaga tgaataatgg
      361 caggtagcag cttgtgatat agggagttct aaggctccaa gtgcaatgac tcaagcagaa
      421 attaaactgt gctctttgtt gctacaagag cattttggtg agattgtaga aaaaattgga
      481 gtccacctaa tcagaactgg gagccagcca cttagagtaa ttgcccatga cacaaaagca
      541 tcactggacc aggtgaaaaa agccctttgt gtcctcattc accataacct ggtcatctat
      601 catgtgcata aacgcggtgt ggtggagtat gaagcccaat gcagccgggt actgcggatg
      661 cttcggtacc cccggtacat ctatactacc aaaacactgt atggtgacac tggagagctg
      721 attgttgagg agcttctgct gaatggcaaa atgacaatgt cggctgttgt gaagaaagta
      781 gcagaccgac tcacagagac catggaggat ggcaagacca tggactacgc tgaggtgtca
      841 aatgcatttg ttcgactggc agatactcac tttgtacagc gctgtcccct ggttcctgac
      901 actgacagtt ctgaccccgg gccgccgcca cctgccccaa accttgtcat taatgaaaag
      961 gacatgtacc tagttcccaa actgagcttg ataggaaaag gtaagaggag gagatcatct
     1021 gacgaagatg ctgctggaga gcccaaggcc aagaaaccaa gatgcacaga taatgaggag
     1081 cccacaccag acgatgggat ttattggcaa gtcaacctgg acagattcca ccagcacttc
     1141 cgtgaccaag caattgtgag cgcagtggca aaccgaatgg accagacaag cagcgagatt
     1201 gtgcggacaa tgctccgaat gagtgagatt accactccct ctggtgcgcc gtttactcag
     1261 ccactgtcct ccaatgagat cttcagatcc ctgcccgtcg gatataatat ctctaaacag
     1321 gttctggatc agtacctcac gctgctggca gatgacccac tagaatttat tggaaaggct
     1381 ggcgacagtg gcggaggaat gtatgtcatc aacctccata aggcattagc atccctatcc
     1441 actgcaactc tggagtctgt catccaagag agattcgggt ctcgctgtgc ccggatattc
     1501 cgtctggtgt tgcagaagaa gcacctggag cagaagcagg tggaggactt tgcaatgatc
     1561 cctgcaaagg aggcaaagga catgctgtat aagatgctct cggagaactt catatcactg
     1621 caggaaattc ctaaaacgcc agaccacgcc ccgtccagga ccttctatct gtacaccgtg
     1681 aatgtgctgt cagccgccag gatgctgttg cacaggtgct acaagagcat agccaacttg
     1741 atagaaaggc ggcaatttga aacaaaagag aacaagcggc tactagaaaa gtctcagcgg
     1801 gtggaagcca tcatggcatc aatgcaggcc acgggtgcag aggaggtaca gctgcaggag
     1861 atcgaggaga tgatcacagc ccccgagcgg cagcagctgg agacactgaa acgcaacgtt
     1921 aacaagttgg atgccagtga gatccaggta gatgaaacca tcttcttact ggaatcatac
     1981 atcgagagca ccatgaagag acagtgaccc agaagaagcc attgtgggat caaactcagg
     2041 gcctttcaca tgctagtcaa ctggtgtacc actgagccac atccccaacc ttctcaaaag
     2101 attaggaaat agagaagaag aaggtgcttg gatgtattct ttgcaatgat tgatatgtaa
     2161 tatatcaatc attttatata tatatatata tatatatata tttttttttt ttttaaatgg
     2221 tttttcgaga tggggtttct cgaactcaga ggatcctgct gggattgaag gcgtccaccc
     2281 catgcccagc taccttgaag actctcatac tgaccctctg ttcctgtctt tccctgctgc
     2341 tcgtgacaca cctcctctca tcaaatcctc atggtacgat gaaccttaaa taaatgacaa
     2401 caatcataaa gta
//
