LOCUS       NM_001282325             527 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus RNA polymerase II, I and III subunit K (Polr2k),
            mRNA.
ACCESSION   NM_001282325 XM_003750337 XM_003754300
VERSION     NM_001282325.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 527)
  AUTHORS   Knutson,B.A. and Hahn,S.
  TITLE     TFIIB-related factors in RNA polymerase I transcription
  JOURNAL   Biochim Biophys Acta 1829 (3-4), 265-273 (2013)
   PUBMED   22960599
  REMARK    Review article
REFERENCE   2  (bases 1 to 527)
  AUTHORS   Vannini,A. and Cramer,P.
  TITLE     Conservation between the RNA polymerase I, II, and III
            transcription initiation machineries
  JOURNAL   Mol Cell 45 (4), 439-446 (2012)
   PUBMED   22365827
  REMARK    Review article
REFERENCE   3  (bases 1 to 527)
  AUTHORS   Schneider,D.A.
  TITLE     RNA polymerase I activity is regulated at multiple steps in the
            transcription cycle: recent insights into factors that influence
            transcription elongation
  JOURNAL   Gene 493 (2), 176-184 (2012)
   PUBMED   21893173
  REMARK    Review article
REFERENCE   4  (bases 1 to 527)
  AUTHORS   Dumay-Odelot,H., Durrieu-Gaillard,S., Da Silva,D., Roeder,R.G. and
            Teichmann,M.
  TITLE     Cell growth- and differentiation-dependent regulation of RNA
            polymerase III transcription
  JOURNAL   Cell Cycle 9 (18), 3687-3699 (2010)
   PUBMED   20890107
  REMARK    Review article
REFERENCE   5  (bases 1 to 527)
  AUTHORS   Hu,P., Wu,S., Sun,Y., Yuan,C.C., Kobayashi,R., Myers,M.P. and
            Hernandez,N.
  TITLE     Characterization of human RNA polymerase III identifies orthologues
            for Saccharomyces cerevisiae RNA polymerase III subunits
  JOURNAL   Mol Cell Biol 22 (22), 8044-8055 (2002)
   PUBMED   12391170
REFERENCE   6  (bases 1 to 527)
  AUTHORS   Kershnar,E., Wu,S.Y. and Chiang,C.M.
  TITLE     Immunoaffinity purification and functional characterization of
            human transcription factor IIH and RNA polymerase II from clonal
            cell lines that conditionally express epitope-tagged subunits of
            the multiprotein complexes
  JOURNAL   J Biol Chem 273 (51), 34444-34453 (1998)
   PUBMED   9852112
REFERENCE   7  (bases 1 to 527)
  AUTHORS   Xu,C.
  TITLE     cDNA cloning of a mouse factor that activates transcription from a
            metal response element of the mouse metallothionein-I gene in yeast
  JOURNAL   DNA Cell Biol 12 (6), 517-525 (1993)
   PUBMED   8329119
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AW144706.1 and EX488432.1.
            
            On or before Aug 30, 2013 this sequence version replaced
            XM_003750337.1, XM_003754300.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AW144706.1, CB735015.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-503               AW144706.1         1-503
            504-527             EX488432.1         475-498
FEATURES             Location/Qualifiers
     source          1..527
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q22"
     gene            1..527
                     /gene="Polr2k"
                     /note="RNA polymerase II, I and III subunit K"
                     /db_xref="GeneID:100361574"
                     /db_xref="RGD:2319895"
     exon            1..83
                     /gene="Polr2k"
                     /inference="alignment:Splign:2.1.0"
     exon            84..153
                     /gene="Polr2k"
                     /inference="alignment:Splign:2.1.0"
     CDS             93..269
                     /gene="Polr2k"
                     /EC_number="2.7.7.6"
                     /note="mCG145114-like; polymerase (RNA) II (DNA directed)
                     polypeptide K; RNA polymerase II subunit K"
                     /codon_start=1
                     /product="DNA-directed RNA polymerases I, II, and III
                     subunit RPABC4"
                     /protein_id="NP_001269254.1"
                     /db_xref="GeneID:100361574"
                     /db_xref="RGD:2319895"
                     /translation="MDTQKDVQPPKQQPMIYICGECHTENEIKSRDPIRCRECGYRIM
                     YKKRTKRLVVFDAR"
     exon            154..246
                     /gene="Polr2k"
                     /inference="alignment:Splign:2.1.0"
     exon            247..504
                     /gene="Polr2k"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agcgccggta gtgtctcttg cttctaagag ccggagaaag cgtttgcgtg cacagaggag
       61 ggacgctttc cggagctgcg gaggcacgaa caatggacac ccagaaagat gttcaaccac
      121 caaagcagca gccaatgata tatatttgtg gagagtgtca caccgaaaat gaaataaaat
      181 ccagggatcc aatcagatgc agagaatgtg gatacagaat aatgtacaag aaaaggacta
      241 agagattggt ggtttttgat gctcgatgaa acagtggagt tgaggaatgt cttcatacat
      301 ttgcctcgtt gatgtttctc tttaatgtat agcatttaac ttagcttact taatgactac
      361 aactgtgtac ctatgatttc attttagaaa tgccaattgt attttaatac tctgtataaa
      421 ggaaatttcg ggtcaacata tgacttaatt tattgtcctt gtaattcctc atacagtgaa
      481 gattaaaagt gtttctccaa accaaaaaaa aaaaaaaaaa aaaaaaa
//
