LOCUS       XM_343922               6758 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus RNA polymerase II subunit A (Polr2a),
            transcript variant X1, mRNA.
ACCESSION   XM_343922
VERSION     XM_343922.8
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051345.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Jan 9, 2024 this sequence was replaced by
            NM_001427041.1.
            
            On Jan 21, 2021 this sequence version replaced XM_343922.7.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6758
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..6758
                     /gene="Polr2a"
                     /note="RNA polymerase II subunit A; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 38
                     ESTs, 6 long SRA reads, 8 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 236 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:363633"
                     /db_xref="RGD:1587326"
     CDS             436..6348
                     /gene="Polr2a"
                     /codon_start=1
                     /product="DNA-directed RNA polymerase II subunit RPB1
                     isoform X1"
                     /protein_id="XP_343923.3"
                     /db_xref="GeneID:363633"
                     /db_xref="RGD:1587326"
                     /translation="MHGGGPPSGDSACPLRTIKRVQFGVLSPDELKRMSVTEGGIKYP
                     ETTEGGRPKLGGLMDPRQGVIERTGRCQTCAGNMTECPGHFGHIELAKPVFHVGFLVK
                     TMKVLRCVCFFCSKLLVDSNNPKIKDILAKSKGQPKKRLTHVYDLCKGKNICEGGEEM
                     DNKFGVEQPEGDEDLTKEKGHGGCGRYQPRIRRSGLELYAEWKHVNEDSQEKKILLSP
                     ERVHEIFKRISDEECFVLGMEPRYARPEWMIVTVLPVPPLSVRPAVVMQGSARNQDDL
                     THKLADIVKINNQLRRNEQNGAAAHVIAEDVKLLQFHVATMVDNELPGLPRAMQKSGR
                     PLKSLKQRLKGKEGRVRGNLMGKRVDFSARTVITPDPNLSIDQVGVPRSIAANMTFAE
                     IVTPFNIDRLQELVRRGNSQYPGAKYIIRDNGDRIDLRFHPKPSDLHLQTGYKVERHM
                     CDGDIVIFNRQPTLHKMSMMGHRVRILPWSTFRLNLSVTTPYNADFDGDEMNLHLPQS
                     LETRAEIQELAMVPRMIVTPQSNRPVMGIVQDTLTAVRKFTKRDVFLERGEVMNLLMF
                     LSTWDGKVPQPAILKPRPLWTGKQIFSLIIPGHINCIRTHSTHPDDEDSGPYKHISPG
                     DTKVVVENGELIMGILCKKSLGTSAGSLVHISYLEMGHDVTRLFYSNIQTVINNWLLI
                     EGHTIGIGDSIADSKTYQDIQNTIKKAKQDVIEVIEKAHNNELEPTPGNTLRQTFENQ
                     VNRILNDARDKTGSSAQKSLSEYNNFKSMVVSGAKGSKINISQVIAVVGQQNVEGKRI
                     PFGFKHRTLPHFIKDDYGPESRGFVENSYLAGLTPTEFFFHAMGGREGLIDTAVKTAE
                     TGYIQRRLIKSMESVMVKYDATVRNSINQVVQLRYGEDGLAGESVEFQNLATLKPSNK
                     AFEKKFRFDYTNERALRRTLQEDLVKDVLSNAHIQNELEREFERMREDREVLRVIFPT
                     GDSKVVLPCNLLRMIWNAQKIFHINPRLPSDLHPIKVVEGVKELSKKLVIVNGDDPLS
                     RQAQENATLLFNIHLRSTLCSRRMAEEFRLSGEAFDWLLGEIESKFNQAIAHPGEMVG
                     ALAAQSLGEPATQMTLNTFHYAGVSAKNVTLGVPRLKELINISKKPKTPSLTVFLLGQ
                     SARDAERAKDILCRLEHTTLRKVTANTAIYYDPNPQSTVVAEDQEWVNVYYEMPDFDV
                     ARISPWLLRVELDRKHMTDRKLTMEQIAEKINAGFGDDLNCIFNDDNAEKLVLRIRIM
                     NSDENKMQEEEEVVDKMDDDVFLRCIESNMLTDMTLQGIEQISKVYMHLPQTDNKKKI
                     IITEDGEFKALQEWILETDGVSLMRVLSEKDVDPVRTTSNDIVEIFTVLGIEAVRKAL
                     ERELYHVISFDGSYVNYRHLALLCDTMTCRGHLMAITRHGVNRQDTGPLMKCSFEETV
                     DVLMEAAAHGESDPMKGVSENIMLGQLAPAGTGCFDLLLDAEKCKYGMEIPTNIPGLG
                     AAGPTGMFFGSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAAS
                     DASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTP
                     QSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTS
                     PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPS
                     YSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYS
                     PTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPT
                     SPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSP
                     VYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTS
                     PAISPEDSDEEN"
ORIGIN      
        1 agggcgtcat tcagccagtt ctctcctcag aagcgccgag agcgcgaccg ggacggttgg
       61 agaagaaggt ggctcccgga agggggagag acaaactgcc gtaacctctg ccgttcagga
      121 tcccggttac ttatttattc gttacccctt ttcttcttcc tccctcccac aacctcttcc
      181 tttcctccct tcttttgttt cctttttggg agtcgacgaa tctccggaaa gggaaagaag
      241 gctttctttc ggcccttttc gtttctccgc cttcctcctt cctcccctcc cccacctttc
      301 cctcctccgg cctttctctt cttattctgg gaggtctttc ctggaggccg cccggacggg
      361 ttctgagcac ttaggcggcg gtggcgcagg ctttttgtag cgagatttgc gcctgcgcag
      421 cgcgtctgcc tcgccatgca cgggggtggc cctccctccg gggacagcgc atgcccgctg
      481 cgcaccatca agagagtgca gttcggcgtc ctgagtccgg atgagttgaa gcggatgtct
      541 gtgacagagg gtggtatcaa atacccagag acaacagagg gtggtcgccc caaacttggg
      601 ggactaatgg atccacgaca gggggtgatt gagcggactg gccgttgtca aacatgtgca
      661 ggaaacatga ccgagtgtcc tggccacttt ggccacattg aactggccaa gcctgtgttt
      721 catgtgggct tcctggtgaa gacaatgaag gttttgcgct gtgtctgctt cttttgctcc
      781 aaacttcttg tagattctaa caacccgaag attaaggaca tcctggccaa atctaagggg
      841 cagcccaaga aacggcttac acatgtctat gacctttgca agggcaaaaa catctgtgaa
      901 ggtggagagg agatggacaa caagtttggt gtggagcagc ctgaggggga tgaggatctg
      961 accaaagaaa agggccatgg tggctgtggg cgttatcagc cccggatccg gcgctctggc
     1021 ctggagttgt atgctgaatg gaaacatgtt aatgaggact ctcaggagaa gaagatcttg
     1081 ctgagtccag aacgagtgca tgaaatcttc aaacgcatct cagatgagga gtgttttgtg
     1141 ctgggcatgg agcctcgcta tgcccggcct gagtggatga ttgtcacggt gttgcctgtg
     1201 cctcctctct ctgtgcgacc tgctgtggtg atgcaaggtt ctgctcgaaa ccaggatgat
     1261 ctgactcaca aactggctga cattgtgaag atcaacaatc agctgcggcg gaacgaacag
     1321 aatggtgcag ctgcccatgt catcgcagaa gatgtgaaac ttctccagtt ccatgtggcc
     1381 accatggtgg acaacgaact gcccggctta ccccgtgcca tgcagaagtc tggccgtccc
     1441 ctcaagtccc tgaagcaacg gttgaagggc aaggaaggac gggttcgagg gaatctaatg
     1501 ggcaagcgag tggacttctc agcccgcact gtcatcaccc ctgaccctaa cctatccatt
     1561 gaccaagttg gtgtgccccg ctccattgct gccaacatga cctttgcaga gattgtcaca
     1621 cctttcaaca ttgacagact tcaggaatta gtacgcaggg gaaacagcca gtatccagga
     1681 gccaagtaca tcatccgaga caacggtgat cgaattgact tacggttcca tcctaagccc
     1741 agtgaccttc acctacagac tggctataag gtggaacggc acatgtgtga tggggacatt
     1801 gttatcttca atcgtcagcc aactttgcac aaaatgtcca tgatggggca tcgggtccgc
     1861 atcctcccct ggtctacatt tcgcttgaat cttagtgtga caactccata caatgcagac
     1921 tttgatggag atgagatgaa tttgcacctg cctcagtctc tggagacacg ggcagagatc
     1981 caagagttgg ccatggtacc tcgaatgatt gtcactcccc agagcaatcg acctgtcatg
     2041 ggtattgtgc aagacacact cacagcggtc cgcaaattca ctaagagaga tgtcttcctg
     2101 gagcggggtg aagtgatgaa cctcttaatg ttcctgtcca cgtgggatgg gaaggtccca
     2161 cagccagcca tcctcaagcc ccggcccctg tggacaggca agcaaatctt ctccctcatc
     2221 atacctggtc acatcaattg tatccgtact cacagcaccc atcctgatga tgaagatagt
     2281 ggcccttaca agcacatctc tcctggggac accaaagtgg tggtggagaa tggggagctt
     2341 atcatgggca tcctttgtaa gaagtctctg ggcacatcag caggctctct ggtccacatc
     2401 tcctacttag agatgggtca tgacgttacc cgcctcttct actccaacat tcagactgtc
     2461 attaacaact ggcttctcat cgagggtcat accattggca ttggggactc cattgcagat
     2521 tccaagactt accaggacat tcagaacact attaagaaag ctaaacagga tgtaatagag
     2581 gtcattgaga aggctcataa caatgagcta gaacccaccc caggaaacac attgcgccag
     2641 acatttgaga atcaagtgaa tcgcattctc aatgatgctc gagacaaaac tggctcctct
     2701 gcacagaaat ccctctctga atataacaac ttcaagtcta tggtggtgtc tggagctaaa
     2761 gggtccaaga tcaacatctc ccaggtcatt gccgttgtcg ggcagcagaa cgtggagggc
     2821 aagcggatcc catttggatt taagcatcgg actcttcctc actttatcaa ggatgattat
     2881 ggtcccgaga gccgaggctt tgtagaaaac tcctacttgg ctggcctcac tcccactgag
     2941 ttcttcttcc atgccatggg aggacgagaa ggtctcattg acacagctgt taagactgct
     3001 gagactgggt atattcagcg aaggctgata aaatccatgg agtcggtgat ggtgaaatat
     3061 gatgcaactg tgaggaactc catcaaccag gtggtacagc tacgctatgg agaggacggc
     3121 ctagcaggcg agagcgttga gttccagaat ctggctacac ttaagccttc taataaagct
     3181 tttgagaaga agttccgttt tgattatacc aatgagaggg ccctgcggcg gactcttcag
     3241 gaggatctgg taaaggatgt gctgagcaat gcccacatac agaatgagct agaacgggaa
     3301 tttgaacgga tgcgggaaga tcgggaagtg ctcagggtca tcttcccaac tggtgacagc
     3361 aaggtggtcc tcccttgtaa ccttctgcgg atgatctgga atgcacagaa aatcttccat
     3421 atcaaccctc gccttccctc tgacctgcac cccatcaaag tggtagaggg agtcaaagaa
     3481 ttgagcaaga agttggtaat tgtgaatgga gatgacccac taagtcggca ggcacaggag
     3541 aatgccactt tgctcttcaa catccaccta agatccacac tttgctctcg ccgaatggct
     3601 gaggagtttc ggctcagtgg agaggccttt gactggctgc tcggggagat agagtccaag
     3661 ttcaaccaag ccattgccca tcctggagaa atggtgggag ctttggctgc tcagtctctt
     3721 ggagaacctg ccactcagat gaccctgaac actttccact atgctggtgt atctgccaag
     3781 aatgtgacgc tgggtgtacc tcggcttaag gagctcatca acatctctaa gaagccaaag
     3841 accccttcac tcactgtctt cctgttaggc caatctgccc gagacgctga gcgggccaag
     3901 gacattcttt gccgcttgga acatacaaca ttgaggaagg tgactgccaa cacagccatc
     3961 tactatgacc ccaaccctca gagcacagtg gtggcagaag atcaggagtg ggtgaatgtg
     4021 tactatgaga tgcctgactt tgatgtagcc cgaatatccc cctggctgct gcgtgtggaa
     4081 ctggaccgaa agcacatgac tgaccggaag cttaccatgg aacagattgc tgaaaaaatc
     4141 aatgcaggct ttggcgatga tttgaattgt atcttcaatg atgataatgc agagaagctg
     4201 gtccttcgta tccgcatcat gaacagtgat gaaaacaaga tgcaggagga ggaagaggtg
     4261 gtggataaga tggatgatga tgttttcctg cggtgcattg agtccaacat gctgacagat
     4321 atgaccctgc agggtattga gcagatcagc aaggtataca tgcacttacc tcagacagac
     4381 aacaagaaga agatcatcat cacagaagat ggggagttca aggccctgca agaatggatc
     4441 ttggagacag atggtgtgag cctgatgcgg gtgctgagcg agaaggatgt agaccctgtg
     4501 cgcactacgt ccaatgacat cgtggagatc ttcacggtac tgggcattga ggctgtgcgg
     4561 aaggccctgg agcgagaact gtaccatgtc atctcctttg atggttccta cgtcaattat
     4621 cggcatttgg ctcttctgtg tgacacaatg acatgccgtg gccacttgat ggccatcact
     4681 cgtcatggag tcaaccgcca ggacactgga ccactcatga aatgctcctt tgaggaaacg
     4741 gtggatgtcc ttatggaagc agctgcacat ggggagagtg accccatgaa gggagtctct
     4801 gagaatatta tgctgggcca gctcgctcca gctggtactg gctgttttga cctcctgctt
     4861 gatgctgaga aatgcaaata cggcatggaa atccccacca atatccccgg actgggggcc
     4921 gctggaccta ctggcatgtt ctttggctct gcacccagtc cgatgggagg aatctctcct
     4981 gcaatgacac cctggaacca gggtgcaact ccagcctatg gtgcctggtc cccaagtgtt
     5041 gggagtggga tgaccccagg agcagctggc ttctctccca gtgctgcatc tgatgccagt
     5101 ggcttcagcc caggttactc gcctgcatgg tctcccacac caggctctcc aggctcccct
     5161 ggaccctcaa gcccatatat cccctcacca ggtggtgcta tgtctcccag ctactcacca
     5221 acatcaccag catatgagcc gcgctcccct gggggctata caccgcagag cccctcatac
     5281 tcccctactt ctccttccta ctccccaacg tctccgtctt attctccaac cagtcccaac
     5341 tatagtccta cctcacctag ctactcccca acctctccta gctattcccc aacctctcca
     5401 tcctactcac caacctctcc atcctactca ccaacctctc ccagctactc cccaacctct
     5461 cccagctact ccccaacatc acccagctat tctccaactt ctcccagcta ctcaccaaca
     5521 tctcctagct attccccaac atctcccagc tactcaccaa cctctccaag ctattctccc
     5581 acctccccca gttactcacc gacatctcca agctactcac caacttctcc aagttactca
     5641 ccaacttccc caagttactc acccactagc cctaactatt ccccaactag tcccaactat
     5701 accccaacct cacccagcta cagcccaacc tcacccagct actcacctac tagtccaaac
     5761 tatacaccta ccagccctaa ctacagccca acctctccaa gctattcccc aacctcaccc
     5821 agttactctc ccacctcacc cagctactct ccctcgagcc cacggtatac acctcagtct
     5881 ccaacctaca caccgagttc accaagctac agccctagct cgccaagcta cagccctact
     5941 tcccccaagt ataccccaac tagtccttcc tacagtccta gctcaccaga gtatacccca
     6001 acttctccca aatactcacc tacaagcccc aaatattcac ccacttctcc caagtattct
     6061 cctaccagcc ccacttactc acccaccacc ccaaaatact cgccaacctc tcctacatat
     6121 tcaccaacct ctccagtcta caccccgacc tctcccaagt actcccctac tagtcctacc
     6181 tactccccaa cttctcccaa gtactcgccc accagtccca cctactcacc cacctctccc
     6241 aagggctcca cctactctcc cacttctcct ggctactccc ccaccagccc cacctacagc
     6301 ctcaccagtc cagccatcag cccagaagac agcgatgagg agaactgaga gtgagcagga
     6361 cacagcagca gctggttagg gtcagacagc ctccgtggcc tgtgggtcac ttccctcaca
     6421 ggctgtgacc ctagcctggg tcccttgtac ataactcctt atgatgaaac cctctggaag
     6481 ttttggaccc catttttgat gggccttttg ccttgtgctc ctaccccttg tgctgtctcg
     6541 gactcactga tccagctgca gggttgggtg ccctgccagc tccctgcctg actccaccat
     6601 gaaggtcttg cttgcctgtg acttgattgg aattacaggt attttaactt tggaaggcta
     6661 gttcctgctt tgggtcacat ctgatctgga agaacaaagc ttaagctgcc tttgttattt
     6721 tttgaaattg aaataaagtt tactaatttt gaccaaga
//
