LOCUS       NM_001106934            3877 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus POF1B, actin binding protein (Pof1b), mRNA.
ACCESSION   NM_001106934 XM_001062157 XM_228452
VERSION     NM_001106934.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3877)
  AUTHORS   Padovano V, Lucibello I, Alari V, Della Mina P, Crespi A, Ferrari
            I, Recagni M, Lattuada D, Righi M, Toniolo D, Villa A and Pietrini
            G.
  TITLE     The POF1B candidate gene for premature ovarian failure regulates
            epithelial polarity
  JOURNAL   J Cell Sci 124 (Pt 19), 3356-3368 (2011)
   PUBMED   21940798
REFERENCE   2  (bases 1 to 3877)
  AUTHORS   Lacombe A, Lee H, Zahed L, Choucair M, Muller JM, Nelson SF,
            Salameh W and Vilain E.
  TITLE     Disruption of POF1B binding to nonmuscle actin filaments is
            associated with premature ovarian failure
  JOURNAL   Am J Hum Genet 79 (1), 113-119 (2006)
   PUBMED   16773570
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473969.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001062157.1, XM_228452.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN16676807
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3877
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq31"
     gene            1..3877
                     /gene="Pof1b"
                     /gene_synonym="RGD1560798"
                     /note="POF1B, actin binding protein"
                     /db_xref="GeneID:302328"
                     /db_xref="RGD:1560798"
     exon            1..63
                     /gene="Pof1b"
                     /gene_synonym="RGD1560798"
                     /inference="alignment:Splign:2.1.0"
     exon            64..398
                     /gene="Pof1b"
                     /gene_synonym="RGD1560798"
                     /inference="alignment:Splign:2.1.0"
     CDS             114..1877
                     /gene="Pof1b"
                     /gene_synonym="RGD1560798"
                     /note="premature ovarian failure 1B"
                     /codon_start=1
                     /product="protein POF1B"
                     /protein_id="NP_001100404.1"
                     /db_xref="GeneID:302328"
                     /db_xref="RGD:1560798"
                     /translation="MMSSSYWSETSSSSCGTQQPTEVLQCQPQHYHCYHQSSQAQQPP
                     EKNVVYERVRTYSGPMNKVVQALDPLGSREVLSPLKPASSYQNLVWSDHSQELHSPTL
                     KISTCAPSTLHITQNAEQELHSPTVKVTTYPQTTIRRYIVQNPDQEPLSPFLRGGQFF
                     PGNNVIYEKTIRKVEKLNTDQECCPQIQCHHHVIQQPQIIHSPHCQQSHSSHQIQCIT
                     ENDSNVGHELCHGGPSQIHEQLIIQDDGPEKLDPKYFGELLADLSRKNTDLYHCLLEH
                     LERIGGSKQDFETADTSEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFS
                     NIREELGHLQNDLTSLENDKIRLEKDLAFKENQIKEYEELLASVRANNRQQQQGLQDS
                     SSKCQTLEENNLSLRHTLSDMEYRLKELEYCKRNLEQENKNLRIQVSETCTGSMLQGK
                     MDEIGNHYMEMVKNLRLEKDREISKLRSQLNQYQKDVSKREGSCSDFQFKLHELTSLL
                     EEKDSLIKRQSEELSKLRQEIYSSHNQPSGGGRTTITTKKYRTQYPILGLLYDDYEYI
                     PPGSDTQTIVIEKTEDKWTCP"
     exon            399..473
                     /gene="Pof1b"
                     /gene_synonym="RGD1560798"
                     /inference="alignment:Splign:2.1.0"
     exon            474..554
                     /gene="Pof1b"
                     /gene_synonym="RGD1560798"
                     /inference="alignment:Splign:2.1.0"
     exon            555..656
                     /gene="Pof1b"
                     /gene_synonym="RGD1560798"
                     /inference="alignment:Splign:2.1.0"
     exon            657..830
                     /gene="Pof1b"
                     /gene_synonym="RGD1560798"
                     /inference="alignment:Splign:2.1.0"
     exon            831..961
                     /gene="Pof1b"
                     /gene_synonym="RGD1560798"
                     /inference="alignment:Splign:2.1.0"
     exon            962..989
                     /gene="Pof1b"
                     /gene_synonym="RGD1560798"
                     /inference="alignment:Splign:2.1.0"
     exon            990..1064
                     /gene="Pof1b"
                     /gene_synonym="RGD1560798"
                     /inference="alignment:Splign:2.1.0"
     exon            1065..1157
                     /gene="Pof1b"
                     /gene_synonym="RGD1560798"
                     /inference="alignment:Splign:2.1.0"
     exon            1158..1271
                     /gene="Pof1b"
                     /gene_synonym="RGD1560798"
                     /inference="alignment:Splign:2.1.0"
     exon            1272..1424
                     /gene="Pof1b"
                     /gene_synonym="RGD1560798"
                     /inference="alignment:Splign:2.1.0"
     exon            1425..1544
                     /gene="Pof1b"
                     /gene_synonym="RGD1560798"
                     /inference="alignment:Splign:2.1.0"
     exon            1545..1673
                     /gene="Pof1b"
                     /gene_synonym="RGD1560798"
                     /inference="alignment:Splign:2.1.0"
     exon            1674..1756
                     /gene="Pof1b"
                     /gene_synonym="RGD1560798"
                     /inference="alignment:Splign:2.1.0"
     exon            1757..1871
                     /gene="Pof1b"
                     /gene_synonym="RGD1560798"
                     /inference="alignment:Splign:2.1.0"
     exon            1872..3877
                     /gene="Pof1b"
                     /gene_synonym="RGD1560798"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctgccagacc tgctcctgct gctgctccgg taactcatct ttaagcacca ccagggataa
       61 aagggagagc acctggggaa actctgggga aactgtttct gaccaccgag aagatgatga
      121 gctcaagtta ttggagtgag accagcagca gcagttgtgg gacccagcag cccacggagg
      181 tcctgcagtg ccagcctcag cattaccact gctaccatca gtcaagtcaa gcccagcagc
      241 ctccagaaaa aaatgtagtg tatgagcgag tgaggaccta cagtgggcct atgaacaagg
      301 tggtgcaggc cttggacccc ctcggctcac gggaagtgct ctcccctctc aaaccagcct
      361 cctcctacca aaatttggtt tggagcgacc attctcagga gctccattct ccaactctga
      421 aaatatctac ttgtgcacca agcactctcc atataacaca aaatgctgaa caggaactcc
      481 attctccaac agtgaaagtt actacatatc cacaaaccac cattagaaga tacatagtac
      541 aaaatcctga ccaggaacca ttgtcccctt tcctaagagg aggtcaattc ttcccaggaa
      601 acaatgtcat ttatgaaaaa acaataagaa aagtggagaa actaaacaca gatcaggaat
      661 gctgtcctca aattcagtgc catcatcatg tcatccagca accccagatc atccactcac
      721 cacattgtca gcagtcccat tctagccatc agatccaatg tataacagaa aatgattcaa
      781 atgttgggca tgaactctgt catggtgggc caagccaaat acatgaacag ttgataattc
      841 aggatgatgg ccctgaaaaa ttggatccca aatattttgg agagttgctt gctgacctga
      901 gccgcaagaa tacagaccta tatcactgct tgttagaaca tttggagaga attggaggaa
      961 gcaaacaaga ttttgagact gcagatacat cagaagacat tgagtcattg attcccaaag
     1021 gactgtcaga gtttacaaaa cagcaaattc gttatattct gcagatgagg ggtatgtctg
     1081 acaagtccct gcgactagtg ctctccacat tcagcaacat acgggaggaa cttggacatc
     1141 ttcaaaatga tttgacatca ctggaaaatg acaagataag acttgaaaag gacttggcat
     1201 tcaaggaaaa tcaaataaaa gagtatgaag aactcttggc atcagtgaga gcaaataatc
     1261 gccaacagca acaaggactt caagactcaa gctcaaaatg tcagacattg gaagaaaata
     1321 acctttctct tcgacataca ctgtcggaca tggaatacag actaaaagaa cttgaatatt
     1381 gtaaacgtaa tttagaacaa gagaataaaa accttagaat acaggtgtct gagacttgca
     1441 cgggctcgat gctacagggt aaaatggatg agattggcaa ccattatatg gagatggtca
     1501 aaaacttgag acttgagaaa gatagagaaa tcagcaagct aaggtctcaa ttaaaccagt
     1561 accaaaaaga tgtttcaaaa agagaaggaa gttgtagtga tttccaattc aaacttcatg
     1621 aattgacaag tttgctggaa gagaaggatt ctcttataaa gcgtcaatca gaggaactct
     1681 caaagttgag acaagaaata tattcatccc ataaccaacc ctctgggggt ggaaggacta
     1741 caatcaccac aaaaaagtac agaacacagt atccaatcct aggtctcctg tacgatgact
     1801 atgaatatat accaccaggt agtgatacac aaactattgt gatcgagaaa acagaagaca
     1861 aatggacttg tccataaatg gattcgttct acaacactac aacccaaagg aaattttctt
     1921 tgtctgcatg agtattttaa ttgtcattct tctattgcta aagtgcaatc aaattgtgaa
     1981 tcacggtact actccatgga tctaatggaa tgatttaatt ctggagatga gttttcccag
     2041 tcattcagga gacctgagtc cttcttttac acactgatgt atttgatatg acaccatgca
     2101 aatgggagaa aaaacctttg tgtttaaact ccgattgcag acagtgtaga ccctaacttg
     2161 ctatttttat ataggacgct tcctgtatgt tgaacttatt catacagtag agtctttaca
     2221 actgttaaat gtgcaactca actacaggat tcagtcctgt ttttcagcaa aacggaagca
     2281 cagaacaatt aaatgtaaaa aatgggttaa ctagaacatg aaatagacaa cctaaatgta
     2341 cttttttcac attaagcttg tgactaaaag gaatactgca gtgctaacat atcttggaaa
     2401 cagctaagtc aaaggtggag gttaattttg ttaatcatgg aaatgagcta atatctttta
     2461 aataaatgca ttaattaaat tatacatttt gcaacttggt tctaagtaca tgtcagtacc
     2521 tgggaaaatc tgttctttta aaaactattt tctgcaagtg accccattca ctttgcataa
     2581 accatataat actgtgctgt agtagtgggg caatatgaat gtagaatttt tcatagtgat
     2641 atacaaacat attgcatagt catcttaaat aatgcaatta gcagtaaaag atacttgata
     2701 gctgtttctt acttggagaa tatttcataa tagagtcttt gatatattta gaaatttgtt
     2761 agttgaataa caatgacttt acaaaatgat acaagtattt gtttattgta ttacaaaaat
     2821 gaaattttat aatataaccc aattaaaagg tataaaaatt tgtccatcaa attaggatta
     2881 atgtaacaaa tttattcagg ttacatgttt agttcatagt tttgtagtaa aatgtctaca
     2941 gaaaccttta taaaattctt caatggtttg taagcatatt ctaatttttc taagaagcag
     3001 ttaatacaag catggctgtg gcaatgtatg agctaaaact atgagttaga aatatttaaa
     3061 agtcttgata tgaaattaag agtcttattt atattcgtat aacacttaag ataatcatta
     3121 agttctctga catgaatgtc tagtttatca acattttatg atataaaatg ttaatgattc
     3181 atattcttac aattcccctt tactttatga tcagataagt ttctccctct gctacctact
     3241 cttataagca attatggcaa aagtatattg ttttccatct attacaaaag ttacaatgga
     3301 atgctttaat taccttaaca gaaaaatgcc ataattacag tttgaaaatg agaattaagt
     3361 ctttttcaaa atgactgaaa gctaatgata tctagaatta aacagcaatt aagaagactg
     3421 tttgatctaa gatagtgaat tagagtcata taaaagtttc tcattatttt tactaacatt
     3481 ttaagatcaa tagaaataag agggggaagt gatactaatt aaattataca ttcaaatctg
     3541 gagatgtttt cgccaagtca ttcaggagac ctgagtctgt tttttataca ttgatatatt
     3601 tgctataatg tcatgcaaat gagatgggga aaacaacctt tgtgtttaaa ctctgattgc
     3661 agagtagacc ctaacttgct atttttatat aggatgcttc ctgtattcac caattccatg
     3721 tagttactca atgcaaattc tggtggcctc aggtgaagat gtctgtttat ctcatttcta
     3781 tttccatatg ttttcacttt agatttgtca aataaaatgg agactggaga gtgtcatgca
     3841 aaatattctt atgtctaaat aaaatatgtt aagcaac
//
