LOCUS       NM_001398583            3022 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus POC1 centriolar protein B (Poc1b), mRNA.
ACCESSION   NM_001398583 XM_002729781
VERSION     NM_001398583.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3022)
  AUTHORS   Beck,B.B., Phillips,J.B., Bartram,M.P., Wegner,J., Thoenes,M.,
            Pannes,A., Sampson,J., Heller,R., Gobel,H., Koerber,F.,
            Neugebauer,A., Hedergott,A., Nurnberg,G., Nurnberg,P., Thiele,H.,
            Altmuller,J., Toliat,M.R., Staubach,S., Boycott,K.M., Valente,E.M.,
            Janecke,A.R., Eisenberger,T., Bergmann,C., Tebbe,L., Wang,Y.,
            Wu,Y., Fry,A.M., Westerfield,M., Wolfrum,U. and Bolz,H.J.
  TITLE     Mutation of POC1B in a severe syndromic retinal ciliopathy
  JOURNAL   Hum Mutat 35 (10), 1153-1162 (2014)
   PUBMED   25044745
REFERENCE   2  (bases 1 to 3022)
  AUTHORS   Venoux,M., Tait,X., Hames,R.S., Straatman,K.R., Woodland,H.R. and
            Fry,A.M.
  TITLE     Poc1A and Poc1B act together in human cells to ensure centriole
            integrity
  JOURNAL   J Cell Sci 126 (Pt 1), 163-175 (2013)
   PUBMED   23015594
REFERENCE   3  (bases 1 to 3022)
  AUTHORS   Jakobsen,L., Vanselow,K., Skogs,M., Toyoda,Y., Lundberg,E.,
            Poser,I., Falkenby,L.G., Bennetzen,M., Westendorf,J., Nigg,E.A.,
            Uhlen,M., Hyman,A.A. and Andersen,J.S.
  TITLE     Novel asymmetrically localizing components of human centrosomes
            identified by complementary proteomics methods
  JOURNAL   EMBO J 30 (8), 1520-1535 (2011)
   PUBMED   21399614
REFERENCE   4  (bases 1 to 3022)
  AUTHORS   Pearson,C.G., Osborn,D.P., Giddings,T.H. Jr., Beales,P.L. and
            Winey,M.
  TITLE     Basal body stability and ciliogenesis requires the conserved
            component Poc1
  JOURNAL   J Cell Biol 187 (6), 905-920 (2009)
   PUBMED   20008567
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Dec 20, 2021 this sequence version replaced XM_002729781.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360186.2607698.1,
                                           SRR26360181.2654035.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-153               JAXUCZ010000007.1  35810820-35810972
            154-238             JAXUCZ010000007.1  35811527-35811611
            239-410             JAXUCZ010000007.1  35828636-35828807
            411-590             JAXUCZ010000007.1  35832591-35832770
            591-698             JAXUCZ010000007.1  35852627-35852734
            699-814             JAXUCZ010000007.1  35852861-35852976
            815-948             JAXUCZ010000007.1  35862458-35862591
            949-1017            JAXUCZ010000007.1  35864756-35864824
            1018-1170           JAXUCZ010000007.1  35865670-35865822
            1171-1251           JAXUCZ010000007.1  35876110-35876190
            1252-1467           JAXUCZ010000007.1  35907133-35907348
            1468-3022           JAXUCZ010000007.1  35911017-35912571
FEATURES             Location/Qualifiers
     source          1..3022
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q13"
     gene            1..3022
                     /gene="Poc1b"
                     /note="POC1 centriolar protein B"
                     /db_xref="GeneID:100362836"
                     /db_xref="RGD:2323942"
     exon            1..153
                     /gene="Poc1b"
                     /inference="alignment:Splign:2.1.0"
     CDS             139..1572
                     /gene="Poc1b"
                     /note="rCG49027-like; WD repeat-containing protein 51B"
                     /codon_start=1
                     /product="pOC1 centriolar protein homolog B"
                     /protein_id="NP_001385512.1"
                     /db_xref="GeneID:100362836"
                     /db_xref="RGD:2323942"
                     /translation="MASGPEDPILERYFKGHKAAITSADFSPNCKQIATASWDTFLML
                     WSLKPHARAYRYVGHKDVVTSLQFSPQGNLLASASRDKTVRLWVLDRKGKSSEFKAHT
                     APVRSVDFSADGQFLVTASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIV
                     SCSEDKTIKIWDTTSKQCVNNFSDSVGFANFVDFSPNGTCIASAGSDHAVRIWDIRMN
                     RLLQHYQVHSCGVNCLSFHPSGNSLVTASSDGTVKILDLVEGRLIYTLQGHTGPVFTV
                     SFSKDGELFTSGGADAQVLVWRTSFNQVHYRDPSKRNLKRLHLEASPHLLDIYPRTPH
                     GHEDKRETIEINPKLEVMDLHSSSPPVVDVLSFDSTTTADSTCRAVPGKGEDICRYFL
                     NPLLMPECSSTIMKKKPEDVGDPPSENQRSVPLAVADALEHIMEQLNILTQTVSILEQ
                     RLSLTEDKLKDCLENQQKLFSVIQQKS"
     exon            154..238
                     /gene="Poc1b"
                     /inference="alignment:Splign:2.1.0"
     exon            239..410
                     /gene="Poc1b"
                     /inference="alignment:Splign:2.1.0"
     exon            411..590
                     /gene="Poc1b"
                     /inference="alignment:Splign:2.1.0"
     exon            591..698
                     /gene="Poc1b"
                     /inference="alignment:Splign:2.1.0"
     exon            699..814
                     /gene="Poc1b"
                     /inference="alignment:Splign:2.1.0"
     exon            815..948
                     /gene="Poc1b"
                     /inference="alignment:Splign:2.1.0"
     exon            949..1017
                     /gene="Poc1b"
                     /inference="alignment:Splign:2.1.0"
     exon            1018..1170
                     /gene="Poc1b"
                     /inference="alignment:Splign:2.1.0"
     exon            1171..1251
                     /gene="Poc1b"
                     /inference="alignment:Splign:2.1.0"
     exon            1252..1467
                     /gene="Poc1b"
                     /inference="alignment:Splign:2.1.0"
     exon            1468..3022
                     /gene="Poc1b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gccgccgttg ttgtagtgac cgggaagcgc ccgcactccg ggctgacggt tccgggcgcc
       61 gcacggtccc cccccccacc ccccttgtcc ctacccttcc ctgctccccc aaggccccgg
      121 gtgccgtccg ctccccgcat ggcctccggc ccggaggatc cgattctgga acgttatttt
      181 aaaggtcaca aagctgcgat cacctccgct gacttcagcc ccaactgcaa acaaattgct
      241 actgcttcct gggacacctt tctcatgcta tggagtttga agccacacgc tagagcttac
      301 agatacgtgg gccacaagga tgttgtgacc agtctgcagt tctctccaca aggaaactta
      361 ttagcctctg cctcgagaga taaaaccgtt agactctggg ttcttgacag gaaaggaaag
      421 tcttcagaat ttaaagcaca cacagcccca gttcgaagtg tggacttttc agctgatggc
      481 cagtttctgg ttacagcatc tgaagacaaa tccattaaag tatggagtat gtaccgtcag
      541 cgcttcctct actccctgta ccgacacaca cactgggtac gctgcgccaa attttcaccc
      601 gacgggagat tgatcgtgtc atgtagtgag gataaaacta ttaaaatctg ggacactaca
      661 agcaagcagt gtgttaataa cttctcggac tccgtaggat ttgcaaattt tgtggacttt
      721 agccctaatg gtacatgcat agcttcagcg ggttctgatc acgctgtgag aatctgggat
      781 ataagaatga acagattact tcaacactat caagttcaca gctgcggtgt gaactgtctg
      841 tccttccatc cttcgggtaa cagccttgtc actgcctcgt ctgacggaac agttaagatt
      901 ctggatctcg tagagggaag actcatatac acacttcaag gacatacggg gcccgtcttt
      961 actgtttcat tctccaagga tggagagtta ttcacatccg gtggtgcaga tgcacaggtc
     1021 ttagtatgga ggaccagctt caatcaagtg cactatcgag atcctagtaa acgaaacctc
     1081 aaaagactgc accttgaggc ctccccacac cttcttgaca tctacccacg aacaccacat
     1141 ggccatgaag acaaaaggga gacgattgaa atcaatccaa aacttgaggt aatggacttg
     1201 cacagttctt ctcccccagt tgtggatgtc ctttcttttg attcaaccac aacagcggat
     1261 tccacctgtc gagctgtgcc aggcaagggt gaagacatct gtaggtattt cttgaaccct
     1321 ttgttaatgc cagaatgttc atcaacaatc atgaaaaaga aaccagaaga tgtaggtgac
     1381 ccgccctctg aaaaccagag aagtgtaccg ctagccgtgg ctgacgctct ggagcatatt
     1441 atggaacaac tgaacattct cacccagact gtttccattc tagagcaacg actgtctttg
     1501 accgaagata agctgaaaga ctgccttgag aatcagcaaa agcttttcag tgtcatccaa
     1561 cagaagagct gagcaggagg tgtgcaagct caggctggtc cctgaagacg tactcacaca
     1621 ctcaggacgt tgcagaggcc ctccctccac accctgccat gcactgatca ctgtagattc
     1681 ttcaggggtg agcaacagaa caaaggttca agtcatttgt aaggactgac ttaaacacac
     1741 aaatcactat caaggatcaa gttaagctcc tcccaggtac aattgcagta ataaagttat
     1801 gaacatttaa atcaccccat tccccctccc ccatgttgtt tgaaatgtca gcttctattt
     1861 aatgtgccaa tcctcaccag gaaagtaagc agacctctag atctcattgt taaatcattt
     1921 ccaagtgacc atgttcaggc aattcctgaa ggtaattagt gttatttctt aggtgagcac
     1981 acccttgagg ggaaagcatt cgcttgcttt caaatagcat ctgagatgta gaaaacctgt
     2041 cattgagttg gctcatagtt ctttcaggtc aaaaaaaaaa aacaatctgc ctcgaaaaga
     2101 tgctccctca gaatttccac agcaagaatc agcttatttt gattagcaag agtgcttaca
     2161 tgacagagca ggcgtgttcc tcgtctgatg ggaactgcat gaggcatttg tgtctctcct
     2221 gttacaggtg aacgcactga gcggtctggg tcatactgaa cctgtgacca cagtccatag
     2281 agattatgtt tgtgtggtgt cagtgtgcta aaaagccaaa atgataaaaa atatgtggat
     2341 atacacgaat cgcatactgt tgcttagggt gatcctggtg gctgaaatag cacattttta
     2401 tttagaaaaa gattgcaaca tctattttat tttaatgaat tgtgatttga aatgaaaacg
     2461 agtcaggcat tctgaaagat cttggttaca agttgagaat gtttctctat ctcaaacaaa
     2521 atgggaatca aagtaaaaaa gagcaaattc aggggttggg gatttagctc agcggcagag
     2581 cacttgccta gcgagcgcaa ggccctgggt tcagtcccca gctctgaaaa aaagaaaaaa
     2641 aaaagaaaaa aaaaaaaaaa agagcaaatt caaggcagcc agctcgggga gaacgaaggc
     2701 cacgcagggc tgtgtagcca gggcagatgc catctgtgca cggaaaacgg agagacagcg
     2761 gcgtggggat ggagagactg ttctccaagc agtctcagtt gtgtgcctct gagctggttt
     2821 tgtcttccgt ctcgctgtgt gttgtaagtg ccctctctgt cctgcgactg tgaccgtctt
     2881 gacattttca cgagctcaca ataccaagtg gccatgtatt tttatacctt cgttgagaag
     2941 attgcataag aaaatgaaat gtaataccaa cttttgttta ctctttttta tgcttcaaat
     3001 aaagatactt ctctttttta aa
//
