LOCUS       NM_001109296            1682 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus POC1 centriolar protein A (Poc1a), mRNA.
ACCESSION   NM_001109296 XM_001073443 XM_039081981 XM_576463
VERSION     NM_001109296.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1682)
  AUTHORS   Geister,K.A., Brinkmeier,M.L., Cheung,L.Y., Wendt,J., Oatley,M.J.,
            Burgess,D.L., Kozloff,K.M., Cavalcoli,J.D., Oatley,J.M. and
            Camper,S.A.
  TITLE     LINE-1 Mediated Insertion into Poc1a (Protein of Centriole 1 A)
            Causes Growth Insufficiency and Male Infertility in Mice
  JOURNAL   PLoS Genet 11 (10), e1005569 (2015)
   PUBMED   26496357
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1682)
  AUTHORS   Venoux,M., Tait,X., Hames,R.S., Straatman,K.R., Woodland,H.R. and
            Fry,A.M.
  TITLE     Poc1A and Poc1B act together in human cells to ensure centriole
            integrity
  JOURNAL   J Cell Sci 126 (Pt 1), 163-175 (2013)
   PUBMED   23015594
REFERENCE   3  (bases 1 to 1682)
  AUTHORS   Jakobsen,L., Vanselow,K., Skogs,M., Toyoda,Y., Lundberg,E.,
            Poser,I., Falkenby,L.G., Bennetzen,M., Westendorf,J., Nigg,E.A.,
            Uhlen,M., Hyman,A.A. and Andersen,J.S.
  TITLE     Novel asymmetrically localizing components of human centrosomes
            identified by complementary proteomics methods
  JOURNAL   EMBO J 30 (8), 1520-1535 (2011)
   PUBMED   21399614
REFERENCE   4  (bases 1 to 1682)
  AUTHORS   Pearson,C.G., Osborn,D.P., Giddings,T.H. Jr., Beales,P.L. and
            Winey,M.
  TITLE     Basal body stability and ciliogenesis requires the conserved
            component Poc1
  JOURNAL   J Cell Biol 187 (6), 905-920 (2009)
   PUBMED   20008567
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On or before Feb 4, 2022 this sequence version replaced
            XM_039081981.1, NM_001109296.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ233502.1, SRR26360172.391830.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-369               JAXUCZ010000008.1  115801396-115801764
            370-454             JAXUCZ010000008.1  115803109-115803193
            455-626             JAXUCZ010000008.1  115805279-115805450
            627-806             JAXUCZ010000008.1  115805809-115805988
            807-914             JAXUCZ010000008.1  115807493-115807600
            915-1030            JAXUCZ010000008.1  115808793-115808908
            1031-1164           JAXUCZ010000008.1  115815984-115816117
            1165-1233           JAXUCZ010000008.1  115825959-115826027
            1234-1326           JAXUCZ010000008.1  115828772-115828864
            1327-1470           JAXUCZ010000008.1  115850078-115850221
            1471-1682           JAXUCZ010000008.1  115869601-115869812
FEATURES             Location/Qualifiers
     source          1..1682
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q32"
     gene            1..1682
                     /gene="Poc1a"
                     /gene_synonym="RGD1565004; Wdr51a"
                     /note="POC1 centriolar protein A"
                     /db_xref="GeneID:501048"
                     /db_xref="RGD:1565004"
     exon            1..369
                     /gene="Poc1a"
                     /gene_synonym="RGD1565004; Wdr51a"
                     /inference="alignment:Splign:2.1.0"
     CDS             352..1569
                     /gene="Poc1a"
                     /gene_synonym="RGD1565004; Wdr51a"
                     /note="WD repeat-containing protein 51A; WD repeat domain
                     51A"
                     /codon_start=1
                     /product="POC1 centriolar protein homolog A"
                     /protein_id="NP_001102766.2"
                     /db_xref="GeneID:501048"
                     /db_xref="RGD:1565004"
                     /translation="MAAHSQEDPSLERHFKGHRDAVTCVDFSLNTKHLASGSMDSTLM
                     IWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAH
                     TATVRSVHFCSDGQLLVTASDDKTVKVWSTHRQRFLFSLTQHINWVRCAKFSPDGRLI
                     VSASDDKTVKLWDKTSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDTRT
                     HRLVQHYQLHSAAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATT
                     VAFSRTGEYFASGGSDEQVMVWKSNFDTVDYGDMKARRPPPQASSAGTPPEMDLPVPP
                     GRDRSLESVHSDAQEPISMPQTLTSTLEHIVGQLDVLTQTVSILEQRLTLTEDRLKQC
                     LENQQLIMQRTPP"
     exon            370..454
                     /gene="Poc1a"
                     /gene_synonym="RGD1565004; Wdr51a"
                     /inference="alignment:Splign:2.1.0"
     exon            455..626
                     /gene="Poc1a"
                     /gene_synonym="RGD1565004; Wdr51a"
                     /inference="alignment:Splign:2.1.0"
     exon            627..806
                     /gene="Poc1a"
                     /gene_synonym="RGD1565004; Wdr51a"
                     /inference="alignment:Splign:2.1.0"
     exon            807..914
                     /gene="Poc1a"
                     /gene_synonym="RGD1565004; Wdr51a"
                     /inference="alignment:Splign:2.1.0"
     exon            915..1030
                     /gene="Poc1a"
                     /gene_synonym="RGD1565004; Wdr51a"
                     /inference="alignment:Splign:2.1.0"
     exon            1031..1164
                     /gene="Poc1a"
                     /gene_synonym="RGD1565004; Wdr51a"
                     /inference="alignment:Splign:2.1.0"
     exon            1165..1233
                     /gene="Poc1a"
                     /gene_synonym="RGD1565004; Wdr51a"
                     /inference="alignment:Splign:2.1.0"
     exon            1234..1326
                     /gene="Poc1a"
                     /gene_synonym="RGD1565004; Wdr51a"
                     /inference="alignment:Splign:2.1.0"
     exon            1327..1470
                     /gene="Poc1a"
                     /gene_synonym="RGD1565004; Wdr51a"
                     /inference="alignment:Splign:2.1.0"
     exon            1471..1682
                     /gene="Poc1a"
                     /gene_synonym="RGD1565004; Wdr51a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcttcgttac cagagctaga gctgaaaggc cgaaaccttc atctaggatt ttttaagttc
       61 tcaggaggaa agtgtgacag cgaagtgaag cttttggctg ctcggccggt tacctcatct
      121 ggcagagcta gaggacaaga acgtggcgcc catcgagcaa cccaacttcc ggtcggaggg
      181 caaaaaccta gggcgcttct cctttaattg cggtgggcgg gacgcggcga cgccaccggc
      241 gttgctattg gcggcgattg ggggcgcgga aactgaactg gcacaactgt cgacccagct
      301 atctcccgca tttggggcgc cgctggtact accagccccg ttagccctgc catggctgct
      361 cacagccagg aggacccctc actggagaga cattttaagg gccaccgaga tgcagttacc
      421 tgtgtggact tcagtctcaa caccaagcac ctggccagtg gctccatgga ctcaaccctc
      481 atgatctggc acatgaagcc ccagtcacgt gcctaccgct tcacgggcca caaggacgcc
      541 gtgacttgtg tgaatttctc cccatcggga cacctgcttg cctcaggctc ccgagacaag
      601 accgttcgaa tctgggtacc caatgtcaaa ggtgagtcaa ctgtgttccg tgcacacacg
      661 gccacagtga ggagcgtcca cttctgcagt gatggccagt tgctcgtgac agcctctgat
      721 gacaagacag tcaaggtgtg gtcaactcat cgccagagat tcctgttttc cctgacccag
      781 cacatcaact gggtccgctg tgccaagttc tctcctgacg ggcggctcat cgtgtctgcc
      841 agcgatgaca aaactgtcaa gctgtgggac aagaccagcc gggagtgtgt ccactcatac
      901 tgtgagcacg gcggctttgt cacctacgtg gacttccacc ccagtgggac ctgcattgct
      961 gctgctggca tggacaacac ggtgaaggtg tgggatactc ggactcaccg gctggtgcag
     1021 cactatcagt tacacagcgc agccgtgaat gccctctcct tccacccatc gggaaactac
     1081 ctcatcacag cctccagtga ctcgaccctg aagatcctgg acctgatgga gggccggctg
     1141 ctctacacgc tccatgggca ccagggccct gctaccaccg ttgccttttc aagaacgggg
     1201 gaatatttcg cttctggagg ctctgatgag caggtgatgg tctggaagag taactttgac
     1261 accgttgatt atggagacat gaaggcacgg aggcccccac cccaagccag ctctgctggg
     1321 actccgccag aaatggattt gcccgtccca ccaggcagag acaggagtct ggagtcagtt
     1381 catagtgacg cccaggagcc catcagcatg ccccagacac tgaccagcac acttgagcac
     1441 atcgtgggcc agctggacgt cctcacacag acagtgtcca ttctggagca gcggctgaca
     1501 ctgacagaag acaggctgaa gcaatgcctg gagaaccagc agctaatcat gcagagaaca
     1561 ccaccttgat gaggggagca aggatcagga gctcaattga ttggggggat agcaggccag
     1621 ggatttgtac gggaacttga gtaaataaat aaagggatcc cacccgaggg agccacacct
     1681 ta
//
