LOCUS       NM_001401181             994 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus patatin like phospholipase domain containing 4
            (Pnpla4), transcript variant 1, mRNA.
ACCESSION   NM_001401181 XM_343790
VERSION     NM_001401181.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 994)
  AUTHORS   Kohda,M., Tokuzawa,Y., Kishita,Y., Nyuzuki,H., Moriyama,Y.,
            Mizuno,Y., Hirata,T., Yatsuka,Y., Yamashita-Sugahara,Y.,
            Nakachi,Y., Kato,H., Okuda,A., Tamaru,S., Borna,N.N., Banshoya,K.,
            Aigaki,T., Sato-Miyata,Y., Ohnuma,K., Suzuki,T., Nagao,A.,
            Maehata,H., Matsuda,F., Higasa,K., Nagasaki,M., Yasuda,J.,
            Yamamoto,M., Fushimi,T., Shimura,M., Kaiho-Ichimoto,K.,
            Harashima,H., Yamazaki,T., Mori,M., Murayama,K., Ohtake,A. and
            Okazaki,Y.
  TITLE     A Comprehensive Genomic Analysis Reveals the Genetic Landscape of
            Mitochondrial Respiratory Chain Complex Deficiencies
  JOURNAL   PLoS Genet 12 (1), e1005679 (2016)
   PUBMED   26741492
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 994)
  AUTHORS   Gao,J.G. and Simon,M.
  TITLE     A comparative study of human GS2, its paralogues, and its rat
            orthologue
  JOURNAL   Biochem Biophys Res Commun 360 (2), 501-506 (2007)
   PUBMED   17603008
REFERENCE   3  (bases 1 to 994)
  AUTHORS   Gao,J.G. and Simon,M.
  TITLE     Molecular screening for GS2 lipase regulators: inhibition of
            keratinocyte retinylester hydrolysis by TIP47
  JOURNAL   J Invest Dermatol 126 (9), 2087-2095 (2006)
   PUBMED   16741517
REFERENCE   4  (bases 1 to 994)
  AUTHORS   Jenkins,C.M., Mancuso,D.J., Yan,W., Sims,H.F., Gibson,B. and
            Gross,R.W.
  TITLE     Identification, cloning, expression, and purification of three
            novel human calcium-independent phospholipase A2 family members
            possessing triacylglycerol lipase and acylglycerol transacylase
            activities
  JOURNAL   J Biol Chem 279 (47), 48968-48975 (2004)
   PUBMED   15364929
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000021.1.
            
            On Feb 3, 2022 this sequence version replaced XM_343790.7.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ216301.1, SRR26360194.2026480.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-48                JAXUCZ010000021.1  46204982-46205029   c
            49-207              JAXUCZ010000021.1  46204641-46204799   c
            208-395             JAXUCZ010000021.1  46204206-46204393   c
            396-490             JAXUCZ010000021.1  46203475-46203569   c
            491-623             JAXUCZ010000021.1  46203099-46203231   c
            624-689             JAXUCZ010000021.1  46202577-46202642   c
            690-842             JAXUCZ010000021.1  46202323-46202475   c
            843-994             JAXUCZ010000021.1  46201538-46201689   c
FEATURES             Location/Qualifiers
     source          1..994
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq21"
     gene            1..994
                     /gene="Pnpla4"
                     /gene_synonym="RGD1562200"
                     /note="patatin like phospholipase domain containing 4"
                     /db_xref="GeneID:363471"
                     /db_xref="RGD:1562200"
     exon            1..48
                     /gene="Pnpla4"
                     /gene_synonym="RGD1562200"
                     /inference="alignment:Splign:2.1.0"
     exon            49..207
                     /gene="Pnpla4"
                     /gene_synonym="RGD1562200"
                     /inference="alignment:Splign:2.1.0"
     exon            208..395
                     /gene="Pnpla4"
                     /gene_synonym="RGD1562200"
                     /inference="alignment:Splign:2.1.0"
     CDS             216..974
                     /gene="Pnpla4"
                     /gene_synonym="RGD1562200"
                     /note="isoform a is encoded by transcript variant 1;
                     patatin-like phospholipase domain-containing protein 4"
                     /codon_start=1
                     /product="patatin-like phospholipase domain-containing
                     protein 4 isoform a"
                     /protein_id="NP_001388110.1"
                     /db_xref="GeneID:363471"
                     /db_xref="RGD:1562200"
                     /translation="MKQVHLSFSSCGFLGIYHLGAATVLSKRGRGLLCNVTGFAGASA
                     GALVATLLLTAPERIEACTRFTFAFAEEVRMQALGPLTPGYDFMARLRGGIDEILPQH
                     AHELARERLHVSVTSAVGQNYLVSNFTCRDNLITVLLASCFIPFYAGLKPMDCAGQLC
                     VDGGLTNSLPVLPTGRTVTFSPFSGRADVSPRDLGWPGIYVRVAKQDVMVSMANLVRV
                     QQALFPPSRGMMEAIYGMGMTDTVRFLRRERWSQ"
     exon            396..490
                     /gene="Pnpla4"
                     /gene_synonym="RGD1562200"
                     /inference="alignment:Splign:2.1.0"
     exon            491..623
                     /gene="Pnpla4"
                     /gene_synonym="RGD1562200"
                     /inference="alignment:Splign:2.1.0"
     exon            624..689
                     /gene="Pnpla4"
                     /gene_synonym="RGD1562200"
                     /inference="alignment:Splign:2.1.0"
     exon            690..842
                     /gene="Pnpla4"
                     /gene_synonym="RGD1562200"
                     /inference="alignment:Splign:2.1.0"
     exon            843..994
                     /gene="Pnpla4"
                     /gene_synonym="RGD1562200"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgaaacacga aggcgcagaa cgatgacatc agaagatgtt acttgcagtg aaggagtcgc
       61 tctgcgctac cacattgggt gaagtcgcaa ccacaggcac cgcctaggct ggaccccgcc
      121 gcatcgcgat tggctcagcc gcccagagtg acatctgcct gtgacgccgt cttctaggga
      181 ttggctggaa gtgctgtccc cacaaaacca ctaccatgaa gcaagtccac ctctctttct
      241 catcctgcgg atttctgggt atttaccacc tgggggcagc gactgtactg agcaaacgcg
      301 ggcggggctt gctatgcaat gtcacaggct ttgcaggggc ctcagcaggg gcactggtgg
      361 ccacactgct gctgacagca ccagagagga tagaggcatg taccaggttc acatttgcct
      421 ttgcggagga ggtcagaatg caggcactgg ggcccttgac acctggatat gatttcatgg
      481 cccggctgag gggtggcatt gacgagattc ttccccagca cgcccatgag ctggcacggg
      541 aacggcttca tgtgtcagta accagcgcag ttggacagaa ctacctggtg tccaacttca
      601 catgcaggga caacctcatc acggttctcc tggccagctg cttcataccc ttctacgcag
      661 gactcaagcc catggattgt gcagggcagc tctgtgtgga tggtggcctg accaacagcc
      721 tgcctgtgct gcccacggga cgcaccgtga ccttttcacc cttcagcgga cgggcagatg
      781 tgtcgccacg ggacttgggg tggcctggca tatatgtgag agtcgccaag caggatgtca
      841 tggtgtccat ggctaacctg gtgcgtgtgc agcaggcgct gttcccacca agcaggggga
      901 tgatggaggc gatctatggc atggggatga ccgacacggt gcgctttctg cgcagggaac
      961 gctggtctca ataaatgcag atgtgtgtag ccaa
//
