LOCUS       NM_001395593            1805 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus PARN like ribonuclease domain containing
            exonuclease 1 (Pnldc1), transcript variant 1, mRNA.
ACCESSION   NM_001395593
VERSION     NM_001395593.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1805)
  AUTHORS   Cui,W., Dai,X., Marcho,C., Han,Z., Zhang,K., Tremblay,K.D. and
            Mager,J.
  TITLE     Towards Functional Annotation of the Preimplantation Transcriptome:
            An RNAi Screen in Mammalian Embryos
  JOURNAL   Sci Rep 6, 37396 (2016)
   PUBMED   27869233
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1805)
  AUTHORS   Anastasakis,D., Skeparnias,I., Shaukat,A.N., Grafanaki,K.,
            Kanellou,A., Taraviras,S., Papachristou,D.J., Papakyriakou,A. and
            Stathopoulos,C.
  TITLE     Mammalian PNLDC1 is a novel poly(A) specific exonuclease with
            discrete expression during early development
  JOURNAL   Nucleic Acids Res 44 (18), 8908-8920 (2016)
   PUBMED   27515512
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360181.3301317.1,
                                           SRR26360186.1353400.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-111               JAXUCZ010000001.1  50391006-50391116
            112-169             JAXUCZ010000001.1  50391445-50391502
            170-243             JAXUCZ010000001.1  50391823-50391896
            244-283             JAXUCZ010000001.1  50394044-50394083
            284-407             JAXUCZ010000001.1  50394729-50394852
            408-496             JAXUCZ010000001.1  50395008-50395096
            497-597             JAXUCZ010000001.1  50397194-50397294
            598-674             JAXUCZ010000001.1  50399129-50399205
            675-818             JAXUCZ010000001.1  50399379-50399522
            819-888             JAXUCZ010000001.1  50400664-50400733
            889-974             JAXUCZ010000001.1  50402148-50402233
            975-1030            JAXUCZ010000001.1  50403318-50403373
            1031-1095           JAXUCZ010000001.1  50405711-50405775
            1096-1149           JAXUCZ010000001.1  50406181-50406234
            1150-1192           JAXUCZ010000001.1  50406352-50406394
            1193-1289           JAXUCZ010000001.1  50407672-50407768
            1290-1465           JAXUCZ010000001.1  50408022-50408197
            1466-1564           JAXUCZ010000001.1  50408293-50408391
            1565-1805           JAXUCZ010000001.1  50409217-50409457
FEATURES             Location/Qualifiers
     source          1..1805
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q11"
     gene            1..1805
                     /gene="Pnldc1"
                     /note="PARN like ribonuclease domain containing
                     exonuclease 1"
                     /db_xref="GeneID:361478"
                     /db_xref="RGD:1308678"
     exon            1..111
                     /gene="Pnldc1"
                     /inference="alignment:Splign:2.1.0"
     CDS             36..1628
                     /gene="Pnldc1"
                     /EC_number="3.1.13.4"
                     /note="poly(A)-specific ribonuclease PARN-like
                     domain-containing protein 1; poly(A)-specific ribonuclease
                     (PARN)-like domain containing 1; PARN like, ribonuclease
                     domain containing 1"
                     /codon_start=1
                     /product="poly(A)-specific ribonuclease PNLDC1"
                     /protein_id="NP_001382522.1"
                     /db_xref="GeneID:361478"
                     /db_xref="RGD:1308678"
                     /translation="MDVGADEFEQSLPFLQELVAGADFVGLDIEFTGLRSNLSRPQQI
                     SLFDLPSEWYLKTRQSVQQFTICQIGLSMFSSVEGESNKYVAHSCNFFLFPTTFGILD
                     SEFSFQASSVQFLNQYGFDYNKFLKNGIPYMNEEQEKKIKHSILRGNWRVRSSLDKDQ
                     IKVVIDKVTQWLDLAEEGDQMTLPGISGFQAFEVQLVLRQALPNIWTVLKEEGVIVKK
                     VSQPHRWYLEHASCDQVTCWKEQILLSARGFSVFFQMLVKAQKPLVGHNMMTDLLHLH
                     EKFFRPLPESYDQFKQNIHSLFPVLIDTKNVTKDIWKELRFPRVSNLSEVYEVLSSNL
                     NPTKNSGPVIIHARQCKKYAETKCPHEAAYDAFLCGSVLLKVAHLLLQRVHGGAVHEP
                     AFPQYLDVLAPYVNQVNLIRAGVPKINFSGPDYPSIRPPVLILTVKRWPGVSEHQVYR
                     EFQNLCKFDVRRFTRSQFLLLTNKFKDARSVLKEYRSHPTLQVSLYRYWRHSPNITCL
                     LQVCSIVTTWSMIAFLLGRPSP"
     exon            112..169
                     /gene="Pnldc1"
                     /inference="alignment:Splign:2.1.0"
     exon            170..243
                     /gene="Pnldc1"
                     /inference="alignment:Splign:2.1.0"
     exon            244..283
                     /gene="Pnldc1"
                     /inference="alignment:Splign:2.1.0"
     exon            284..407
                     /gene="Pnldc1"
                     /inference="alignment:Splign:2.1.0"
     exon            408..496
                     /gene="Pnldc1"
                     /inference="alignment:Splign:2.1.0"
     exon            497..597
                     /gene="Pnldc1"
                     /inference="alignment:Splign:2.1.0"
     exon            598..674
                     /gene="Pnldc1"
                     /inference="alignment:Splign:2.1.0"
     exon            675..818
                     /gene="Pnldc1"
                     /inference="alignment:Splign:2.1.0"
     exon            819..888
                     /gene="Pnldc1"
                     /inference="alignment:Splign:2.1.0"
     exon            889..974
                     /gene="Pnldc1"
                     /inference="alignment:Splign:2.1.0"
     exon            975..1030
                     /gene="Pnldc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1031..1095
                     /gene="Pnldc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1096..1149
                     /gene="Pnldc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1150..1192
                     /gene="Pnldc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1193..1289
                     /gene="Pnldc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1290..1465
                     /gene="Pnldc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1466..1564
                     /gene="Pnldc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1565..1805
                     /gene="Pnldc1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtggccgcat ccggcgcgcc ctgggactag cggctatgga cgtgggcgcg gacgaatttg
       61 agcagagcct tccattcctg caggaacttg tcgcgggtgc ggacttcgtg ggtctggaca
      121 tagagttcac aggtctgcgt tcaaacctgt cccggcccca acagatcagt ctctttgact
      181 tgccatctga gtggtatctg aagacccgcc aaagtgttca gcagtttaca atctgtcaga
      241 ttggattgtc catgttttcc agcgttgaag gagaatcaaa caagtatgta gcgcactcct
      301 gcaatttctt tctcttccct acaacatttg ggatcctgga ctcagaattc tctttccagg
      361 catctagtgt acagtttctg aatcagtatg gcttcgacta taacaagttc ctcaaaaacg
      421 gaatcccata catgaatgaa gaacaggaga agaaaatcaa gcacagtatc ctgagaggga
      481 actggagagt ccgaagctct ctggataaag accaaatcaa ggtggtgatt gataaggtga
      541 cccagtggct ggacctggct gaggaaggtg accagatgac tctgcctggc atctctgggt
      601 tccaagcctt cgaggtccaa ctggtgctga ggcaggccct ccccaacatc tggacagtgc
      661 tgaaagagga gggggtaatt gtgaagaaag tgagccagcc acatcgctgg taccttgagc
      721 atgcctcttg tgaccaagtc acctgttgga aggagcagat tcttctctct gcaagaggct
      781 tctctgtctt ttttcagatg ttggtgaaag cccagaagcc cttggtagga cataacatga
      841 tgacggacct actgcatctc catgagaagt tcttccgacc tctcccagaa agctacgatc
      901 agtttaagca gaacatccat agcctgttcc ctgtcctcat cgacactaag aacgtgacta
      961 aagacatctg gaaggaactg cgtttcccac gagtctccaa cctctcggaa gtgtatgaag
     1021 tgctgagcag taacttgaat cccactaaga attccggacc ggtgatcatt catgcaagac
     1081 aatgtaaaaa atacgctgag accaagtgcc ctcatgaagc agcctatgac gctttcctct
     1141 gcgggtcagt tctcttgaaa gtggctcact tgcttctaca gagggtgcat ggcggtgctg
     1201 tgcacgagcc tgccttcccc caatacctcg atgtgctggc gccctacgtg aaccaagtga
     1261 atcttatcag agctggggtt ccgaaaatta atttttctgg cccagactac cccagtatcc
     1321 gccctcctgt actcatcctc actgtcaaga ggtggcccgg ggtgagtgag caccaggtct
     1381 accgtgagtt ccagaatctc tgcaagtttg atgtcaggcg gttcactcga agccagttcc
     1441 tgctcctgac caataagttt aaggatgccc gcagtgtctt gaaggaatac aggagccacc
     1501 caaccctgca ggtctccctg taccggtact ggagacattc gcccaacatc acctgcctgc
     1561 tacaggtctg cagcatagtc accacctggt ccatgattgc ctttctcctg ggaagaccta
     1621 gcccctgaca gcagtgagca cctcagcttc ggtcttagcc tctgaggatg gccccccgtg
     1681 gctcgtttgc ataaatgagt ttgttttcat gcagacctat gtggtcctct gtagatactc
     1741 tgttgtgttg tgaatgtgag attctgtaaa tatggatgat gataaagaaa cccttgcatg
     1801 tcgga
//
