LOCUS       NM_001135878            5950 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Rattus norvegicus plexin B3 (Plxnb3), mRNA.
ACCESSION   NM_001135878 XM_343841
VERSION     NM_001135878.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5950)
  AUTHORS   Nihonmatsu-Kikuchi,N., Yu,X.J., Matsuda,Y., Ozawa,N., Ito,T.,
            Satou,K., Kaname,T., Iwasaki,Y., Akagi,A., Yoshida,M., Toru,S.,
            Hirokawa,K., Takashima,A., Hasegawa,M., Uchihara,T. and
            Tatebayashi,Y.
  TITLE     Essential roles of plexin-B3+ oligodendrocyte precursor cells in
            the pathogenesis of Alzheimer's disease
  JOURNAL   Commun Biol 4 (1), 870 (2021)
   PUBMED   34267322
  REMARK    GeneRIF: Essential roles of plexin-B3(+) oligodendrocyte precursor
            cells in the pathogenesis of Alzheimer's disease.
            Erratum:[Commun Biol. 2021 Dec 2;4(1):1372. doi:
            10.1038/s42003-021-02905-5.. PMID: 34857866]
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5950)
  AUTHORS   Laht,P., Tammaru,E., Otsus,M., Rohtla,J., Tiismus,L. and Veske,A.
  TITLE     Plexin-B3 suppresses excitatory and promotes inhibitory synapse
            formation in rat hippocampal neurons
  JOURNAL   Exp Cell Res 335 (2), 269-278 (2015)
   PUBMED   25989221
  REMARK    GeneRIF: Plexin-B3 contributes to regulating synapse formation.
REFERENCE   3  (bases 1 to 5950)
  AUTHORS   Li,X. and Lee,A.Y.
  TITLE     Semaphorin 5A and plexin-B3 inhibit human glioma cell motility
            through RhoGDIalpha-mediated inactivation of Rac1 GTPase
  JOURNAL   J Biol Chem 285 (42), 32436-32445 (2010)
   PUBMED   20696765
REFERENCE   4  (bases 1 to 5950)
  AUTHORS   Sadanandam,A., Rosenbaugh,E.G., Singh,S., Varney,M. and Singh,R.K.
  TITLE     Semaphorin 5A promotes angiogenesis by increasing endothelial cell
            proliferation, migration, and decreasing apoptosis
  JOURNAL   Microvasc Res 79 (1), 1-9 (2010)
   PUBMED   19850054
REFERENCE   5  (bases 1 to 5950)
  AUTHORS   Tiismus,L., Laht,P., Otsus,M. and Veske,A.
  TITLE     Identification and characterization of mouse plexin B3 promoter
  JOURNAL   Biochem Biophys Res Commun 375 (1), 11-15 (2008)
   PUBMED   18680721
REFERENCE   6  (bases 1 to 5950)
  AUTHORS   Hartwig,C., Veske,A., Krejcova,S., Rosenberger,G. and Finckh,U.
  TITLE     Plexin B3 promotes neurite outgrowth, interacts homophilically, and
            interacts with Rin
  JOURNAL   BMC Neurosci 6, 53 (2005)
   PUBMED   16122393
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 5950)
  AUTHORS   Artigiani,S., Conrotto,P., Fazzari,P., Gilestro,G.F., Barberis,D.,
            Giordano,S., Comoglio,P.M. and Tamagnone,L.
  TITLE     Plexin-B3 is a functional receptor for semaphorin 5A
  JOURNAL   EMBO Rep 5 (7), 710-714 (2004)
   PUBMED   15218527
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000021.1.
            
            On Oct 16, 2008 this sequence version replaced XM_343841.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360194.1941191.1,
                                           SRR26643298.33655.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMEA5760433
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1056              JAXUCZ010000021.1  156646874-156647929
            1057-1236           JAXUCZ010000021.1  156648229-156648408
            1237-1365           JAXUCZ010000021.1  156649093-156649221
            1366-1466           JAXUCZ010000021.1  156649311-156649411
            1467-1596           JAXUCZ010000021.1  156650185-156650314
            1597-1753           JAXUCZ010000021.1  156650483-156650639
            1754-1862           JAXUCZ010000021.1  156650728-156650836
            1863-1977           JAXUCZ010000021.1  156650920-156651034
            1978-2103           JAXUCZ010000021.1  156651164-156651289
            2104-2220           JAXUCZ010000021.1  156651372-156651488
            2221-2314           JAXUCZ010000021.1  156651792-156651885
            2315-2484           JAXUCZ010000021.1  156651973-156652142
            2485-2636           JAXUCZ010000021.1  156652385-156652536
            2637-2742           JAXUCZ010000021.1  156652764-156652869
            2743-2873           JAXUCZ010000021.1  156653523-156653653
            2874-3050           JAXUCZ010000021.1  156653888-156654064
            3051-3246           JAXUCZ010000021.1  156654167-156654362
            3247-3486           JAXUCZ010000021.1  156654470-156654709
            3487-3648           JAXUCZ010000021.1  156654819-156654980
            3649-3800           JAXUCZ010000021.1  156655049-156655200
            3801-3901           JAXUCZ010000021.1  156655309-156655409
            3902-4125           JAXUCZ010000021.1  156655486-156655709
            4126-4304           JAXUCZ010000021.1  156655865-156656043
            4305-4371           JAXUCZ010000021.1  156656227-156656293
            4372-4699           JAXUCZ010000021.1  156656666-156656993
            4700-4803           JAXUCZ010000021.1  156657121-156657224
            4804-4900           JAXUCZ010000021.1  156657309-156657405
            4901-5079           JAXUCZ010000021.1  156657769-156657947
            5080-5240           JAXUCZ010000021.1  156658092-156658252
            5241-5388           JAXUCZ010000021.1  156658607-156658754
            5389-5453           JAXUCZ010000021.1  156658923-156658987
            5454-5529           JAXUCZ010000021.1  156659055-156659130
            5530-5604           JAXUCZ010000021.1  156659250-156659324
            5605-5950           JAXUCZ010000021.1  156659666-156660011
FEATURES             Location/Qualifiers
     source          1..5950
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq37"
     gene            1..5950
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /note="plexin B3"
                     /db_xref="GeneID:363517"
                     /db_xref="RGD:1560615"
     CDS             1..5709
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /note="protein Plxnb3"
                     /codon_start=1
                     /product="plexin-B3 precursor"
                     /protein_id="NP_001129350.1"
                     /db_xref="GeneID:363517"
                     /db_xref="RGD:1560615"
                     /translation="MLTDFLQAPVMAPWSPFSLHLLLLFLLLLPLTRAHRFSVPNASF
                     NHLVLAPDQGKLYVGAVNHLFQLSPELEMESVAITGPVIDSPDCVPFRDLAECPQAQL
                     TDNANQLLLVSSRAQELVACGQVRQGVCEKRRLGDVTQVLYQAEDPGDGQFVAANTLG
                     VTTVGLVVPLPGRDLLLVARGLAGKLSAGVPPLTVRQLAGPQPFSSEGLGRLVVGDFS
                     DYNNSYVGAFSDAHSAYFVFRRRGARAQTEYRSYVARVCLGDVNLYSYVEVPLTCHGQ
                     GLIQAAFLAPDTLLGAFSAGTSQAQAALCAFPLADLDGSMEQARRLCYTTGGQGPNGM
                     EEATVEYGVTSRCVTLPPDSPESYPCGDEHTPSPIAGRQPLEAQPLLQLGQPISAVAA
                     LQTDGHTIAFLGDTEGQLHKVFLNSSHGQVYHSQQVGPPGSAISPDLLVDNSGDYLYV
                     LTAQQVDRILVAACPQFPNCTTCLQARDPLCGWCILQGRCTRRAECGRAVQPNQWLWS
                     YEDNHCLHIQSLLPAQHPRQEHGQITLSVPGLPNLAMDEYFYCAFGDYNSLAQVEEHH
                     VVCATPPQDRMPPNPPGSDHVTLPLALMFEDVVLAATTFSFYDCSAIQALEVAAPCRT
                     CVSSLWRCHWCPQSSHCVYGERCPEGEKAVYSAQEVDILVRGPEACPQVKGLASPQLV
                     PVGWESHVTLHIENLHYFRGLPALYYCWLELPGKLRKLPAFLEETSRNSGLIHCQAQQ
                     FHPSMSQWELPVPIYVTRGEIQRLDNTGDLHVTLYDCAMGHPDCSHCQAANGSLSCLW
                     CGDGQPACRYGPLCPPGAVEQLCPIPSIDVIEPLTGPPEGGLAITILGSNLGQAFNDV
                     RNAVTVAGQPCNPDPSLYRISARIVCVTSPAPNGTSGPVQVAIKSRPPGISAQHFTYQ
                     DPVLLSLNPQWGPQAGGTQLTIHGQYLQTGGNVSAFVGDQPCPIQEPVCPEAIICHTM
                     PQMEPGEAVVFVVFGHVERKLLTTPFRYTANPQLVEAEPSVSFRGGGRVIRVRGTGLD
                     VVWQPLLSVWLEDEFQVKALGVQAQDVNPRRSCGAPAADPQACIHLESGLLQCSTLCS
                     VNSSSLLLCHSPAVPDGALPKRVFFALDNMQVDFASASGGQGFLYQPNPRLAPLSHEG
                     ITHPYRLKPGHVLDVEGEGLNLGISKEEVQVHIGDGKCLVKTLTLTHLYCEPPQQAPQ
                     PTNGSGTLPQFVVQMGNVRLALGPVQYEAEPMISTFPVEAQVGLGMGAAMLIAAVLLL
                     TLMYRHKSKQALRDYQKVLVQLENLETGVGDQCRKEFTDLMTEMTDLTSDLEASGIPF
                     LDYRTYAERAFFPGHVGCPLQPGLEGPGEEGRRVTVCQGLTQLSNLLNSKLFLLTLIH
                     TLEEQPSFSQRDRCHVASLLSLALHSKLEYLTDIMRTLLGDLAAHYVHKNPKLMLRRT
                     ETMVEKLLTNWLSICLYAFLKEVAGEPLYMLFRAIKYQVDKGPVDAVTGKAKRTLNDS
                     HLLREDVEFRPLTLMALVGPGAGGAAGNSEVHRVPARVLDTDTITQVKEKVLDQIYKG
                     TPFSQRPSVHSLDLEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKVPDGATVVL
                     IPQLHNGGTVSQSLEQTGCHSGENTPMLEDGEEGGVRLWHLVKATEETEGAKVRRSSL
                     RERERERARAKAIPEIYLTRLLSMKGTLQKFVDDTFQAILSMNRPVPIAVKYLFDFLD
                     ELAEKHGIEDPETLHIWKTNSLLLRFWVNALKNPQLIFDVRVSDNEDAILAVIAQTFI
                     DSCMVSEHKVGRDSPVNKLLYAREIPRYKQMVEKYYADIRQSSPASYQEMNSALAELS
                     GNYTSAPNCLEALRELYNHIHRYYDQIISALEEDPVAQKMQLACRLQQVAALVEYKVT
                     DL"
     exon            1..1056
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
     exon            1057..1236
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
     exon            1237..1365
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
     exon            1366..1466
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
     exon            1467..1596
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
     exon            1597..1753
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
     exon            1754..1862
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
     exon            1863..1977
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
     exon            1978..2103
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
     exon            2104..2220
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
     exon            2221..2314
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
     exon            2315..2484
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
     exon            2485..2636
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
     exon            2637..2742
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
     exon            2743..2873
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
     exon            2874..3050
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
     exon            3051..3246
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
     exon            3247..3486
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
     exon            3487..3648
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
     exon            3649..3800
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
     exon            3801..3901
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
     exon            3902..4125
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
     exon            4126..4304
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
     exon            4305..4371
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
     exon            4372..4699
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
     exon            4700..4803
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
     exon            4804..4900
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
     exon            4901..5079
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
     exon            5080..5240
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
     exon            5241..5388
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
     exon            5389..5453
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
     exon            5454..5529
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
     exon            5530..5604
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
     exon            5605..5950
                     /gene="Plxnb3"
                     /gene_synonym="RGD1560615"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgctgactg acttcctcca ggctcctgtg atggctccct ggtctccctt cagcctccac
       61 cttctgctgc tgttcctgct gttgctgccc ttgaccaggg cccatcgctt ctctgttccg
      121 aacgccagct tcaaccacct ggtgctggca ccagaccagg gcaaactcta tgtgggtgca
      181 gtgaatcacc tcttccagct cagccctgag ctggagatgg agtctgtggc tatcactggc
      241 cctgtcattg acagtcctga ttgtgtgcct ttccgtgacc tggctgagtg cccacaggcc
      301 cagctcactg acaatgccaa ccagctcttg ctggtaagca gcagggcaca ggagctggtg
      361 gcttgtggac aagtgaggca gggtgtatgt gagaagcggc gccttgggga tgttactcaa
      421 gtgctgtacc aggcggagga ccctggtgat gggcagtttg tggctgccaa taccctggga
      481 gtgaccacag taggcctagt ggtgcctttg ccaggccgag acctcctgct ggtggccaga
      541 ggcctggcag gcaagctgtc agcaggagtg ccacccctaa ctgtgcgcca gctggctggg
      601 ccacagcctt tctccagcga aggtctggga agacttgtgg tgggtgactt ttcagactat
      661 aacaatagct atgtaggggc tttttctgat gctcattctg cctactttgt cttccgtcgc
      721 cgtggggctc gggcccagac tgagtatcgc tcctatgtag ctcgcgtctg cctcggagat
      781 gtcaaccttt attcctatgt ggaagtgccc cttacctgcc atggccaggg tcttatccag
      841 gctgccttcc ttgctccgga caccttgctg ggcgcatttt cagcaggcac aagtcaggca
      901 caggcagccc tgtgtgcctt tcccttagct gacctggacg ggagtatgga acaagccagg
      961 cgactttgct atactactgg tggtcagggt cccaacggca tggaagaagc cactgtggag
     1021 tatggtgtca catcccgttg tgtcactctg cctcctgact cccccgagtc atacccctgt
     1081 ggtgatgaac acacccccag ccccatcgca ggccgccaac ccctggaggc ccagcctctg
     1141 ctgcagctgg gacagcccat cagtgcagtg gctgctctcc agacagatgg gcacacgata
     1201 gccttcctgg gagacaccga gggtcaacta cataaggtct ttctaaacag ctcccatggc
     1261 caggtatacc attcccagca agtggggccc ccaggctcag ccatcagccc agacctgctg
     1321 gtagacaaca gtggagacta cctctatgtc ctgactgccc agcaggtaga caggatactt
     1381 gtggcagcct gccctcagtt tcctaactgc actacctgcc tccaggccag ggacccactg
     1441 tgtggctggt gcatacttca gggcaggtgc actcggaggg ccgagtgtgg gagagcagtt
     1501 cagccaaacc agtggctatg gagctatgaa gacaaccact gccttcacat ccagagcctg
     1561 ctaccagccc agcacccccg tcaggaacat ggccagatca ctctgtctgt tcctgggctg
     1621 cccaacctgg ccatggatga atacttctac tgtgcctttg gggactacaa cagtctagct
     1681 caggtggaag agcaccatgt ggtctgtgcc acccctcctc aagatcggat gccacctaat
     1741 cctccaggct cagatcatgt caccttgccc ctggccctga tgtttgagga tgtggtattg
     1801 gctgccacca cattctcctt ctatgactgc agcgctattc aggccttgga agtggctgcc
     1861 ccgtgccgca cttgtgtgag cagcctgtgg cggtgccact ggtgccccca gagtagccac
     1921 tgtgtatatg gagagcgctg cccagagggt gaaaaggctg tctacagtgc ccaggaggtg
     1981 gacatcctgg ttcgtggccc agaggcttgc ccccaggtta agggtctagc aagtccccag
     2041 ttggtgcctg tgggctggga gagccatgtg accctgcaca ttgagaacct tcactatttc
     2101 cgaggtctgc ctgccttgta ctattgctgg ctagaactgc ctggaaaact gcgaaagcta
     2161 cctgccttcc tagaggagac atccaggaac tctggcctca ttcactgcca ggcccagcag
     2221 ttccacccct ctatgtctca gtgggagctc ccagtgccca tctatgtaac caggggtgag
     2281 atccagcggc tggacaatac cggtgatctt catgtgactc tatatgactg tgccatgggt
     2341 caccctgact gcagccactg tcaggcagcc aatgggagcc tgagctgctt gtggtgtggt
     2401 gatggccagc ctgcctgccg ctacgggccg ctgtgcccac caggtgctgt ggaacagcta
     2461 tgccctatac ccagcattga tgtgattgaa cccctgactg gtcccccaga aggtggctta
     2521 gccatcacca tcctgggatc caacctgggc caggccttta atgatgtgcg aaatgctgtg
     2581 actgtggctg gccagccctg caaccctgac ccttctctct accgcatctc tgcccggatt
     2641 gtatgtgtca catctcctgc tcccaatggc acttctggac cagtccaagt ggccattaag
     2701 agtcgtcctc ctggcatctc ggcccagcac ttcacctacc aggaccctgt cctgctgagc
     2761 ctgaatcctc agtggggccc ccaggcaggg ggcacccagc tcaccattca tgggcagtac
     2821 ctccagacag gaggcaacgt cagtgctttt gtgggggacc aaccttgccc tattcaagag
     2881 cctgtgtgtc ctgaagccat catatgccac accatgcccc agatggagcc aggagaagca
     2941 gtggtcttcg tagtctttgg ccatgttgaa cgcaaactgc tcaccactcc ttttcgatac
     3001 actgccaacc cccaactggt ggaagcagag cctagtgtca gcttccgagg aggtggacga
     3061 gtgattcgag ttaggggtac aggcttagat gttgtgtggc agcccttgct gtctgtgtgg
     3121 ctggaggatg agttccaagt gaaggctttg ggcgtgcagg cccaggatgt gaacccaagg
     3181 aggagctgtg gtgcccctgc tgcagatcct caggcttgta tccatcttga gagtggctta
     3241 ctacagtgct ccactctctg ctctgtcaac tcatctagtc tcctcctgtg ccacagtcca
     3301 gcggtgccag atggggccct cccaaagcga gtcttctttg ccctagacaa catgcaagta
     3361 gactttgcca gtgctagtgg gggccaggga ttcctctacc agcctaaccc tcgcctggct
     3421 ccacttagtc atgaggggat tactcacccc tatcggctca agccaggtca tgtcctggat
     3481 gtggagggcg agggcctcaa tctggggatc agcaaggagg aggtgcaggt gcatattgga
     3541 gatgggaagt gcctggtgaa gacgctgacg cttactcact tgtactgtga accaccccag
     3601 caagcccctc agcccaccaa tggttcaggc accctgccac agtttgtggt gcagatgggc
     3661 aatgtgcgcc tggctctagg ccctgttcag tatgaagcag agcccatgat atccaccttt
     3721 cctgtggagg cccaggtggg cctgggcatg ggtgctgcca tgctgattgc tgcagtgcta
     3781 ctcctcaccc tcatgtacag gcacaagagc aagcaggcct tgcgagacta tcagaaggta
     3841 ctggtgcagt tggagaacct ggagactggt gtgggtgacc agtgccgcaa ggagttcaca
     3901 gacctgatga ctgagatgac agacctcacc agtgacctag aggccagtgg gattcccttc
     3961 ctggattacc gaacatatgc tgagcgtgct ttcttccctg gccatgttgg ctgcccactg
     4021 cagccagggc tcgaggggcc tggggaagag ggtcgccgtg tcaccgtgtg ccagggtctc
     4081 acacaactct ccaatttgct caacagcaag ctcttccttc tcacactcat ccacacctta
     4141 gaggagcagc caagcttttc ccagagggac cgctgccatg tggcttcact actttctctg
     4201 gctctgcaca gcaagcttga atatttgacc gacatcatga gaactctgct tggtgaccta
     4261 gcagcccatt atgtacacaa gaaccccaag ctcatgttac gcaggacaga gaccatggta
     4321 gagaagctgc tcaccaactg gctatctatc tgtctctacg ccttcttgaa ggaagtggct
     4381 ggtgagccac tgtacatgct cttccgggcc atcaagtacc aggtggacaa gggccctgtg
     4441 gacgctgtga caggcaaggc aaaacgaact ctgaatgaca gccacctact acgagaggat
     4501 gtggagttcc ggcccctgac cctgatggca ttggtgggac caggggctgg tggggcagca
     4561 ggaaacagtg aagtacatcg agtgccagcc cgggtgcttg atacagacac catcacccaa
     4621 gtcaaagaga aggtgttgga tcaaatctac aagggaactc ccttctccca gaggccttca
     4681 gtgcactccc tagaccttga gtggcgctca ggcctagctg gtcacctaac cttgtcagat
     4741 gaggatttga cctctgtgac tcaaaaccac tggaagagac tcaacaccct acaacactac
     4801 aaggtcccag atggagcaac agtggtactc attcctcagc tgcacaatgg tggcactgtc
     4861 tcccagagtc tggagcagac tggctgccat tctggagaga acactcccat gctggaagat
     4921 ggtgaagaag gtggagttcg gctttggcac ctggtaaagg ccactgagga gacagaaggg
     4981 gccaaagtgc ggcgcagcag cctccgggaa cgagaacgag aacgggcacg agccaaggcc
     5041 attcctgaaa tctatcttac tcgcttactt tcaatgaagg gcaccctgca gaagtttgtg
     5101 gatgacacct tccaggccat tcttagcatg aataggcctg tgcctattgc tgttaagtac
     5161 ctatttgact tcttggatga gctggcagag aaacatggca ttgaagatcc agagaccctg
     5221 cacatttgga agacaaacag cttattgctg cgattctggg tgaatgcctt gaagaaccca
     5281 cagctcatct ttgatgttcg agtgtcagac aacgaggatg ccatcttggc tgtcatcgca
     5341 cagaccttca tcgattcctg catggtctca gagcataaag tgggccggga ttccccagtg
     5401 aacaaactgc tctatgcccg ggagatccct cgctacaagc agatggtgga gaagtactat
     5461 gcggacattc gccagagctc tccagcgagc tatcaagaga tgaactcagc tctggctgaa
     5521 ctctctggga attatacttc tgctcccaac tgtctggagg ctcttcgaga actttacaac
     5581 cacatccaca ggtattatga ccagatcatc agtgccctgg aggaggaccc cgtggcccag
     5641 aagatgcagc tggcttgccg cctgcagcag gtcgctgcct tggtggagta caaagtgact
     5701 gatttatgaa ctagggtcaa cgtgatcacc tgagacctgc caacttatag aacagtgagc
     5761 aggatccact gtatgaccct gactaagcag tgactgagga gggggtcagc aaggctatct
     5821 agaatgccta ctacccccat gtgcttgttt ctaatttata atgatcccta ccctctttcc
     5881 cactgtattt atttgcttgc tggaaaatca catctggaaa taaagtagaa atacatcttt
     5941 ttaaaaacaa
//
