LOCUS       NM_001107046            2874 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus plexin domain containing 1 (Plxdc1), mRNA.
ACCESSION   NM_001107046 XM_001081386 XM_220907
VERSION     NM_001107046.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2874)
  AUTHORS   Ghai,R., Bugarcic,A., Liu,H., Norwood,S.J., Skeldal,S.,
            Coulson,E.J., Li,S.S., Teasdale,R.D. and Collins,B.M.
  TITLE     Structural basis for endosomal trafficking of diverse transmembrane
            cargos by PX-FERM proteins
  JOURNAL   Proc Natl Acad Sci U S A 110 (8), E643-E652 (2013)
   PUBMED   23382219
REFERENCE   2  (bases 1 to 2874)
  AUTHORS   Wang,L., Lee,K.Y., Park,H.T. and Kang,D.S.
  TITLE     Expression profile of tumor endothelial marker 7 and a putative
            ligand in the rat spinal cord and dorsal root ganglion
  JOURNAL   Asian Spine J 1 (2), 65-74 (2007)
   PUBMED   20411127
REFERENCE   3  (bases 1 to 2874)
  AUTHORS   Lee,H.K., Kang,D.S., Seo,I.A., Choi,E.J., Park,H.T. and Park,J.I.
  TITLE     Expression of tumor endothelial marker 7 mRNA and protein in the
            dorsal root ganglion neurons of the rat
  JOURNAL   Neurosci Lett 402 (1-2), 71-75 (2006)
   PUBMED   16707219
  REMARK    GeneRIF: TEM7 mRNA expression was localized to the neuronal
            population of the sensory ganglion. Immunohistochemical analysis on
            TEM protein with specific antibodies further supported the spatial
            expression patterns of TEM7 mRNA in the DRG.
REFERENCE   4  (bases 1 to 2874)
  AUTHORS   Lee,H.K., Seo,I.A., Park,H.K. and Park,H.T.
  TITLE     Identification of the basement membrane protein nidogen as a
            candidate ligand for tumor endothelial marker 7 in vitro and in
            vivo
  JOURNAL   FEBS Lett 580 (9), 2253-2257 (2006)
   PUBMED   16574105
REFERENCE   5  (bases 1 to 2874)
  AUTHORS   Lee,H.K., Bae,H.R., Park,H.K., Seo,I.A., Lee,E.Y., Suh,D.J. and
            Park,H.T.
  TITLE     Cloning, characterization and neuronal expression profiles of tumor
            endothelial marker 7 in the rat brain
  JOURNAL   Brain Res Mol Brain Res 136 (1-2), 189-198 (2005)
   PUBMED   15893603
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473948.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_220907.4, XM_001081386.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2874
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q31"
     gene            1..2874
                     /gene="Plxdc1"
                     /gene_synonym="Arl12; Tem7"
                     /note="plexin domain containing 1"
                     /db_xref="GeneID:303505"
                     /db_xref="RGD:1307496"
     exon            1..205
                     /gene="Plxdc1"
                     /gene_synonym="Arl12; Tem7"
                     /inference="alignment:Splign:2.1.0"
     CDS             127..1629
                     /gene="Plxdc1"
                     /gene_synonym="Arl12; Tem7"
                     /note="ADP-ribosylation factor-like 12; plexin
                     domain-containing protein 1; tumor endothelial marker7"
                     /codon_start=1
                     /product="plexin domain-containing protein 1 precursor"
                     /protein_id="NP_001100516.1"
                     /db_xref="GeneID:303505"
                     /db_xref="RGD:1307496"
                     /translation="MRAQLWLLQLLLLCGTARALSPATPAGHDERQGSAWTAKRTRQG
                     WNRRVRESPGQVLKPGKTQLSQDLGGDSLAIDTLPDNRTRVVEDNHNYYVSRVYGPGE
                     QRTRDLWVDLSVANRNHVKVHRILSSSHRQASRVVLSFDFPFYGHPLRQITIATGGFI
                     FMGDVLHRMLTATQYVAPLMANFNPGYSDNSTVAYFDNGTVFVVQWDHVYLQGREDRG
                     SFTFQAALHQDGRIVFGYKEIPMAVLDISSAQHPVKAGLSDAFMILNSSPEVPESRRR
                     TIFEYHRVELDSSKITTTSAVEFTPLPTCLQHQSCDACMSSNLTFNCSWCYVLQRCSS
                     GFDRYRQEWLTYGCAQEAEGKTCEHFQDEGHYSASPDSSFSPSDGGSTTSSSLFIDSL
                     TTEDDTKLNPYAEGDGLPDNSSPKTKGPPVHLGTIVGIVLAVLLVAAIILAGIYISGH
                     PNSNAALFFIERRPHHWPAMKFHNHPNHSTYTEVEPSGHEKEGFVEAEQC"
     exon            206..384
                     /gene="Plxdc1"
                     /gene_synonym="Arl12; Tem7"
                     /inference="alignment:Splign:2.1.0"
     exon            385..528
                     /gene="Plxdc1"
                     /gene_synonym="Arl12; Tem7"
                     /inference="alignment:Splign:2.1.0"
     exon            529..598
                     /gene="Plxdc1"
                     /gene_synonym="Arl12; Tem7"
                     /inference="alignment:Splign:2.1.0"
     exon            599..721
                     /gene="Plxdc1"
                     /gene_synonym="Arl12; Tem7"
                     /inference="alignment:Splign:2.1.0"
     exon            722..840
                     /gene="Plxdc1"
                     /gene_synonym="Arl12; Tem7"
                     /inference="alignment:Splign:2.1.0"
     exon            841..940
                     /gene="Plxdc1"
                     /gene_synonym="Arl12; Tem7"
                     /inference="alignment:Splign:2.1.0"
     exon            941..1036
                     /gene="Plxdc1"
                     /gene_synonym="Arl12; Tem7"
                     /inference="alignment:Splign:2.1.0"
     exon            1037..1118
                     /gene="Plxdc1"
                     /gene_synonym="Arl12; Tem7"
                     /inference="alignment:Splign:2.1.0"
     exon            1119..1179
                     /gene="Plxdc1"
                     /gene_synonym="Arl12; Tem7"
                     /inference="alignment:Splign:2.1.0"
     exon            1180..1312
                     /gene="Plxdc1"
                     /gene_synonym="Arl12; Tem7"
                     /inference="alignment:Splign:2.1.0"
     exon            1313..1348
                     /gene="Plxdc1"
                     /gene_synonym="Arl12; Tem7"
                     /inference="alignment:Splign:2.1.0"
     exon            1349..1509
                     /gene="Plxdc1"
                     /gene_synonym="Arl12; Tem7"
                     /inference="alignment:Splign:2.1.0"
     exon            1510..2874
                     /gene="Plxdc1"
                     /gene_synonym="Arl12; Tem7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caaggccgca acgccgcgca tcgctcgcgg tgcccgcttc gctccggctc cccattctcc
       61 cagccccggg tcgcctcttc tacagccgct gccgctgcgc cgacccggag gtcgtccgcg
      121 cccaccatgc gggctcagct ctggttgctg cagctgctgc tactctgcgg gaccgcgcgc
      181 gcgctcagtc ccgcaacacc cgcaggtcac gatgaaaggc aaggctctgc atggactgcc
      241 aagaggacca ggcaaggctg gaatcggagg gtccgagaga gccctgggca ggtgttaaag
      301 ccaggcaaga cccagctgag ccaggacctg ggtggagact ccctggccat tgacacactt
      361 ccggacaaca ggactagggt ggtggaggac aaccataact actatgtttc ccgtgtctat
      421 ggccctggtg agcaacgaac aagagatctg tgggtagacc tgagtgtagc caaccggaac
      481 cacgtgaagg tccacaggat cctctcaagt tctcaccgac aggcttcgag agtggtcttg
      541 tcctttgatt tccctttcta tgggcatcct ttgcggcaga tcaccatagc aaccggaggc
      601 ttcatcttca tgggggacgt cctccaccgg atgctcacag ctactcagta tgtggcaccc
      661 ctgatggcca acttcaaccc cggctactca gacaactcca cagtcgctta ctttgataat
      721 gggaccgtgt ttgtggttca gtgggaccac gtttacctcc agggccggga ggacaggggt
      781 agcttcacct tccaggcagc ccttcaccaa gatggccgca ttgtctttgg ctacaaagag
      841 atccccatgg ctgtcctgga catcagctct gcccagcacc ctgtcaaagc aggcctgtct
      901 gatgctttca tgattctcaa ttcatcgcca gaggtgccag agtctcggag acggactatc
      961 ttcgaatacc accgtgtgga actggactcc agcaagatca ccaccacctc ggctgtggag
     1021 ttcaccccat tgccaacctg cctccagcat cagagttgcg atgcttgcat gtcctcgaac
     1081 ctgaccttca actgcagctg gtgctatgtc ctgcagagat gttccagtgg ctttgaccgc
     1141 taccgccaag aatggctgac ctatggctgt gcccaggagg cagaaggcaa gacatgcgag
     1201 cacttccaag atgagggcca ctactcagcc tcccctgaca gctcctttag cccctctgat
     1261 ggcggctcca ccacctcttc ctccctcttc atcgacagcc tcaccacaga agatgacacc
     1321 aagttgaatc cctatgcaga aggagacggc cttccagaca actcgtcccc aaagaccaag
     1381 ggtccgcccg tgcacctggg caccatcgtg ggcatcgtgc tagctgtgct cctggtagcg
     1441 gccatcatcc tggctgggat ttacatcagc ggccacccta actccaatgc cgcactcttc
     1501 ttcattgagc ggcgacctca ccactggcca gccatgaagt tccacaacca ccccaaccac
     1561 tccacctaca cagaggtgga gccctcgggc catgagaagg agggcttcgt ggaggcggag
     1621 cagtgctgag agcaccaggc caaagacctg gggacggcgt gaaagacaag tcacagcaaa
     1681 gagaagcgat tgttttcccc tggcctcctc tgagctggtc ctgggccagg aagacaagat
     1741 gacagtttat ggtgccaaaa ctacagtgtg gtcttcaggg ttcaggaaca caaccgtaaa
     1801 ggtttcttaa aggaacacta acctcgcagt tccctgtttc aatgggaaga ggctttgttt
     1861 ttctgggtct ctcggtggtc tgcagctatc acggagcccc tgcccactgg agacagcctc
     1921 ctgttcgacc gctgctcgct gaagcccccg tggtggtcta gggtctatag actcaagcgc
     1981 tgggcttcct aacgatggag tcagtgcact gggctccaaa ctttgtggct ctggaagcct
     2041 gaagaagggg gcccctccat cggagagatc tccctgaggt aagccaagtg agaggagaga
     2101 gaaataacct tggaggactt gtattttctg gccttggtcc tttgcttcat tgtttctgca
     2161 gaggccaggg gcccacatca gcacactgta gcctgcagct cattccgcgc cctgccctgc
     2221 ccctcagtct ccaccttgca agccggtctt gcatggttgc ctgtaataag tgggaccctt
     2281 actgtgccat gagcctggtg cctgcttcac ttgttgacct gttctgttgc cagtgacagt
     2341 agtttccttc aaagggacag acgatttaac tggctcctat ttttccttag aggactcaaa
     2401 ttcttgtaac cattaaaaac aattaggggg ctgggcgtgg tggtgcacga ctttacttcc
     2461 cgaactcagg aagcagaggc aggcggatct ctgagatcaa ggccagactg gtctacagag
     2521 agttacacag agagagcctg acttgaagaa acaagacaaa tgggggggtg ggggaattga
     2581 ggtttctttg agacacccct gcctcaggaa ggggttttcc gttggatcct gctgaagcaa
     2641 ggctgctgtg aaggtagggc ggagaaatct ggtctgggag ggaggggcct tgacctggaa
     2701 agttgcctcc atatctctag ttctgcatag agctttgcga gcagggagtt gtccccgcat
     2761 tcagcctggt tttaacggac ttcctgtggt gggccagggc ggcttcgaaa gaacaatgaa
     2821 aatctagagc tcaccctttt cccaaagaag catcatcagc aaataaatat ggca
//
