LOCUS       NM_001012000            1879 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus phospholipid scramblase 4 (Plscr4), mRNA.
ACCESSION   NM_001012000 XM_236509
VERSION     NM_001012000.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1879)
  AUTHORS   Py B, Basmaciogullari S, Bouchet J, Zarka M, Moura IC, Benhamou M,
            Monteiro RC, Hocini H, Madrid R and Benichou S.
  TITLE     The phospholipid scramblases 1 and 4 are cellular receptors for the
            secretory leukocyte protease inhibitor and interact with CD4 at the
            plasma membrane
  JOURNAL   PLoS One 4 (3), e5006 (2009)
   PUBMED   19333378
  REMARK    Erratum:[PLoS ONE. 2009;4(4). doi:
            10.1371/annotation/657cd713-aaac-4ebb-80ad-3ec8dfb12b42]
REFERENCE   2  (bases 1 to 1879)
  AUTHORS   Lu B, Sims PJ, Wiedmer T, Moser AH, Shigenaga JK, Grunfeld C and
            Feingold KR.
  TITLE     Expression of the phospholipid scramblase (PLSCR) gene family
            during the acute phase response
  JOURNAL   Biochim Biophys Acta 1771 (9), 1177-1185 (2007)
   PUBMED   17590392
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY548832.1.
            
            On Feb 11, 2005 this sequence version replaced XM_236509.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY548832.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132294, SAMD00132296
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1879
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q31"
     gene            1..1879
                     /gene="Plscr4"
                     /gene_synonym="Pls4"
                     /note="phospholipid scramblase 4"
                     /db_xref="GeneID:300900"
                     /db_xref="RGD:1311693"
     exon            1..327
                     /gene="Plscr4"
                     /gene_synonym="Pls4"
                     /inference="alignment:Splign:2.1.0"
     exon            328..355
                     /gene="Plscr4"
                     /gene_synonym="Pls4"
                     /inference="alignment:Splign:2.1.0"
     CDS             349..1329
                     /gene="Plscr4"
                     /gene_synonym="Pls4"
                     /codon_start=1
                     /product="phospholipid scramblase 4"
                     /protein_id="NP_001012000.1"
                     /db_xref="GeneID:300900"
                     /db_xref="RGD:1311693"
                     /translation="MSGVVPTAPEQPTEEAENQVKATTAVPDAPPDYNSHFVPGPAGP
                     AAPPSAGLPMGYYVPQQPGAIPLYHPTGGTHPIQYQPGKYPLTSQPAPIMWMPGPAPM
                     PNCPPGLEYLAQLDNIHVLQHLEPLELMTRFETNNRYDIKNNVDQMVYIVTEDTDDFT
                     RNAYRNLRPFVLRVTDCLGREIMTMQRPFRCTCCCFCCPCARQELEVQCPPGVTIGFV
                     AEHWNLCRASYSIQNEKKESAMRVRGPCATYGCGSDSVFEVNSLDGASNIGSIIRKWN
                     GFLSTMGNADHFEIHFPLALDVKMKAMIFGCCFLIDFMYFERPPPRRSSR"
     exon            356..466
                     /gene="Plscr4"
                     /gene_synonym="Pls4"
                     /inference="alignment:Splign:2.1.0"
     exon            467..690
                     /gene="Plscr4"
                     /gene_synonym="Pls4"
                     /inference="alignment:Splign:2.1.0"
     exon            691..733
                     /gene="Plscr4"
                     /gene_synonym="Pls4"
                     /inference="alignment:Splign:2.1.0"
     exon            734..960
                     /gene="Plscr4"
                     /gene_synonym="Pls4"
                     /inference="alignment:Splign:2.1.0"
     exon            961..1122
                     /gene="Plscr4"
                     /gene_synonym="Pls4"
                     /inference="alignment:Splign:2.1.0"
     exon            1123..1281
                     /gene="Plscr4"
                     /gene_synonym="Pls4"
                     /inference="alignment:Splign:2.1.0"
     exon            1282..1879
                     /gene="Plscr4"
                     /gene_synonym="Pls4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaacaaactg gcttgtccag ggctgggaat gagagctggg tagtgaagct gggagcccag
       61 agagtagctg ctttctgcct ccagcagagg agcggttcgg agctcagccc cgcgggctcc
      121 tctggcgccc acaacttgtt taccctgcgc ttggctgggg ttcaggacgc cagcgcccca
      181 cccttcagga agccctcccg ggaaggctcg ccccgctgcc cggagtggat cgccccagct
      241 tcccagcgcc tcccgccttc ccctgggcag gacaaccgag cgcagccagc aatcgcctgt
      301 agctgcgagc ttagagcggg gccggcggaa taattagaat ccacaaaaat gtcaggtgtg
      361 gtccccacag cccctgagca gcctacagaa gaagcggaaa atcaggtaaa agcaacaact
      421 gctgtgcccg atgctcctcc tgactacaat tctcattttg taccaggccc tgctggacca
      481 gctgcccctc catctgcagg cttgcctatg ggatactacg ttccccagca gcccggtgcc
      541 atccccttgt accatcctac cggtggtacc catccaatcc agtaccagcc tggcaaatat
      601 cccttgacga gtcagcctgc tcccataatg tggatgccgg ggccagctcc aatgcccaac
      661 tgccctcctg gtttggaata cttggctcag ttggacaata tacacgttct tcagcatttg
      721 gagcctctgg aattgatgac acgctttgaa actaataata gatatgatat caagaacaac
      781 gtagaccaga tggtttatat cgtaacagaa gacacagatg actttaccag gaatgcctat
      841 cggaacctaa gaccctttgt gctccgggtc actgactgcc tgggccgaga gatcatgacc
      901 atgcagaggc ctttccgatg cacctgctgt tgcttctgct gcccctgtgc gaggcaagag
      961 ttagaagtgc agtgtcctcc tggagtcacc attggctttg tggcagaaca ctggaactta
     1021 tgcagagcct cttacagcat ccagaatgag aagaaagaaa gtgcgatgag agttcgtggt
     1081 ccatgtgcga cctatggctg tggctctgat tctgtttttg aggtcaactc tctagatgga
     1141 gcatctaaca ttggcagtat tatcaggaag tggaatggct ttttatcaac gatgggaaat
     1201 gcagaccact ttgagattca cttccctttg gccctggatg tgaaaatgaa agcaatgatc
     1261 ttcggctgtt gcttcctcat tgatttcatg tactttgaac gccctcctcc acgacgttca
     1321 tcaagataga agatcagaag aatcgtccgt tgagaacaga atcagagaaa tttgcatcca
     1381 gcttatagcc ttcatttatt agcaagtgta ttcctctggc ttgacacgtg tctcagttga
     1441 gtatttagca gcttgggaca ctaggttatt ctgaaatggc tgcttcatta gcccaatcag
     1501 catacagata cgagcgataa gcaataggca cgtgagctat gggaaaacga cgcccttagt
     1561 tcccaactta acatacagac ataacacgtc ttctgtatct gtccctctct tcttcattgg
     1621 gacaaacttt attctaggtg agaggactgc tactcttacc cgtcatcttt aggagacaag
     1681 aggtgcacag aaagaatgtg ctttaatgtg caaaggaaat gtttcttgtg tgcatgcacc
     1741 agaacactgt tctgcaacgt gcatacaagt tcataaagtt ctcagtgggg aattttattt
     1801 tattacataa taaaacgtat tctctttata ggcagttaat attttctatc catatttctt
     1861 catcccccca gctgggcaa
//
