LOCUS       NM_001191631            1242 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus phospholipid phosphatase 4 (Plpp4), mRNA.
ACCESSION   NM_001191631 XM_219376
VERSION     NM_001191631.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1242)
  AUTHORS   Zhang,X., Zhang,L., Lin,B., Chai,X., Li,R., Liao,Y., Deng,X.,
            Liu,Q., Yang,W., Cai,Y., Zhou,W., Lin,Z., Huang,W., Zhong,M.,
            Lei,F., Wu,J., Yu,S., Li,X., Li,S., Li,Y., Zeng,J., Long,W., Ren,D.
            and Huang,Y.
  TITLE     Phospholipid Phosphatase 4 promotes proliferation and
            tumorigenesis, and activates Ca2+-permeable Cationic Channel in
            lung carcinoma cells
  JOURNAL   Mol Cancer 16 (1), 147 (2017)
   PUBMED   28851360
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1242)
  AUTHORS   Cui,W., Dai,X., Marcho,C., Han,Z., Zhang,K., Tremblay,K.D. and
            Mager,J.
  TITLE     Towards Functional Annotation of the Preimplantation Transcriptome:
            An RNAi Screen in Mammalian Embryos
  JOURNAL   Sci Rep 6, 37396 (2016)
   PUBMED   27869233
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1242)
  AUTHORS   Takeuchi,M., Harigai,M., Momohara,S., Ball,E., Abe,J., Furuichi,K.
            and Kamatani,N.
  TITLE     Cloning and characterization of DPPL1 and DPPL2, representatives of
            a novel type of mammalian phosphatidate phosphatase
  JOURNAL   Gene 399 (2), 174-180 (2007)
   PUBMED   17590538
REFERENCE   4  (bases 1 to 1242)
  AUTHORS   Dahl,E., Kristiansen,G., Gottlob,K., Klaman,I., Ebner,E.,
            Hinzmann,B., Hermann,K., Pilarsky,C., Durst,M.,
            Klinkhammer-Schalke,M., Blaszyk,H., Knuechel,R., Hartmann,A.,
            Rosenthal,A. and Wild,P.J.
  TITLE     Molecular profiling of laser-microdissected matched tumor and
            normal breast tissue identifies karyopherin alpha2 as a potential
            novel prognostic marker in breast cancer
  JOURNAL   Clin Cancer Res 12 (13), 3950-3960 (2006)
   PUBMED   16818692
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Jul 17, 2010 this sequence version replaced XM_219376.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.5589.1,
                                           SRR26643429.3797.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMEA5760433
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-124               JAXUCZ010000001.1  193260764-193260887
            125-233             JAXUCZ010000001.1  193310090-193310198
            234-324             JAXUCZ010000001.1  193319810-193319900
            325-388             JAXUCZ010000001.1  193325094-193325157
            389-513             JAXUCZ010000001.1  193326845-193326969
            514-684             JAXUCZ010000001.1  193376356-193376526
            685-1242            JAXUCZ010000001.1  193389102-193389659
FEATURES             Location/Qualifiers
     source          1..1242
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q37"
     gene            1..1242
                     /gene="Plpp4"
                     /gene_synonym="Ppapdc1a; RGD1306289"
                     /note="phospholipid phosphatase 4"
                     /db_xref="GeneID:309014"
                     /db_xref="RGD:1306289"
     exon            1..124
                     /gene="Plpp4"
                     /gene_synonym="Ppapdc1a; RGD1306289"
                     /inference="alignment:Splign:2.1.0"
     CDS             69..884
                     /gene="Plpp4"
                     /gene_synonym="Ppapdc1a; RGD1306289"
                     /EC_number="3.1.3.4"
                     /note="phosphatidate phosphatase PPAPDC1A; phosphatidic
                     acid phosphatase type 2 domain containing 1A"
                     /codon_start=1
                     /product="phospholipid phosphatase 4"
                     /protein_id="NP_001178560.1"
                     /db_xref="GeneID:309014"
                     /db_xref="RGD:1306289"
                     /translation="MRELAIEIGVRALLFGVFVFTEFLDPFQRVIQPEEIWLYKNPLV
                     QSDNIPTRLMFAISFLTPLAVICVVKIIRRTDKTEIKEAFLAVSLALALNGVCTNTIK
                     LIVGRPRPDFFYRCFPDGVMNSEMHCTGDPDLVSEGRKSFPSIHSSFAFSGLGFTTFY
                     LAGKLHCFTESGRGKSWRLCAAILPLYCAMMIALSRMCDYKHHWQDSFVGGVIGLIFA
                     YICYRQHYPPLANTACHKPYVSLRVPTSLKKEERPTADSAPSLPLEGITEGPV"
     exon            125..233
                     /gene="Plpp4"
                     /gene_synonym="Ppapdc1a; RGD1306289"
                     /inference="alignment:Splign:2.1.0"
     exon            234..324
                     /gene="Plpp4"
                     /gene_synonym="Ppapdc1a; RGD1306289"
                     /inference="alignment:Splign:2.1.0"
     exon            325..388
                     /gene="Plpp4"
                     /gene_synonym="Ppapdc1a; RGD1306289"
                     /inference="alignment:Splign:2.1.0"
     exon            389..513
                     /gene="Plpp4"
                     /gene_synonym="Ppapdc1a; RGD1306289"
                     /inference="alignment:Splign:2.1.0"
     exon            514..684
                     /gene="Plpp4"
                     /gene_synonym="Ppapdc1a; RGD1306289"
                     /inference="alignment:Splign:2.1.0"
     exon            685..1242
                     /gene="Plpp4"
                     /gene_synonym="Ppapdc1a; RGD1306289"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctccggccg agtcgtggga gccacggacg gcgccagctg ccgctgcggg agctactctg
       61 gctgcaccat gcgggagctg gccattgaga tcggggtgcg agccctgctc ttcggggtct
      121 tcgtttttac agagtttttg gatccattcc agagagtcat ccagccggaa gagatctggc
      181 tctataaaaa tcctttggtg cagtcagaca acatacctac ccgcctcatg tttgcaattt
      241 ccttcctcac acccttggct gttatttgtg tggtgaaaat tatccggcgg acagacaaga
      301 ctgaaattaa ggaagccttc ttagcagtgt ccttggctct tgctttgaat ggagtctgca
      361 caaacactat taaattgata gtgggaagac ctcgccccga tttcttttac cgctgctttc
      421 cagatggggt gatgaattca gagatgcact gcacaggtga ccctgacctg gtgtcggagg
      481 gccgcaaaag cttccccagt atccattcct cctttgcctt ctcgggcctc ggtttcacaa
      541 cattctacct ggctggcaag ttgcactgct tcacggagag tgggcggggg aagagctggc
      601 ggctctgtgc agccatattg cccttgtact gtgccatgat gatcgccctg tcccgcatgt
      661 gtgactacaa gcatcactgg caagattctt ttgttggagg agtgattggc ctcatttttg
      721 cctatatttg ctacagacag cattaccctc ctctggccaa cacagcatgc cacaaaccgt
      781 atgtcagcct ccgagtgccc acctcactga agaaggagga gaggcctaca gccgacagtg
      841 cacccagctt gcccctggag gggatcaccg agggccccgt atgacgggtg tctaaggaag
      901 agtggacgct gagcccctgg ctcattcttc taccctgatg tcataacaca gtagaacgga
      961 tttcctgtca tgtgatcctc tcatcagtta ctccgaagtc ccctcagctt ccgttttgtg
     1021 gatggcgttc ttgccactct ctatgtctcc tttcaacact ttgactttgt aaagttggga
     1081 caccaggacc agtctctgag agacccatgc ataaggaagg aggatccaag ggcggagtgg
     1141 gcatgcttgc tcatgccgtg attcctttac ctgaggtgtt tgctgtagca cccaccctcc
     1201 tgtgttcatg ttgtgaaaca taataaagtc ccacctagaa gg
//
