LOCUS       NM_001399329            1944 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus perilipin 3 (Plin3), mRNA.
ACCESSION   NM_001399329 XM_236783
VERSION     NM_001399329.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1944)
  AUTHORS   Guo,Z., Neilson,L.J., Zhong,H., Murray,P.S., Zanivan,S. and
            Zaidel-Bar,R.
  TITLE     E-cadherin interactome complexity and robustness resolved by
            quantitative proteomics
  JOURNAL   Sci Signal 7 (354), rs7 (2014)
   PUBMED   25468996
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1944)
  AUTHORS   Moessinger,C., Kuerschner,L., Spandl,J., Shevchenko,A. and
            Thiele,C.
  TITLE     Human lysophosphatidylcholine acyltransferases 1 and 2 are located
            in lipid droplets where they catalyze the formation of
            phosphatidylcholine
  JOURNAL   J Biol Chem 286 (24), 21330-21339 (2011)
   PUBMED   21498505
REFERENCE   3  (bases 1 to 1944)
  AUTHORS   Grasselli,E., Voci,A., Pesce,C., Canesi,L., Fugassa,E., Gallo,G.
            and Vergani,L.
  TITLE     PAT protein mRNA expression in primary rat hepatocytes: Effects of
            exposure to fatty acids
  JOURNAL   Int J Mol Med 25 (4), 505-512 (2010)
   PUBMED   20198297
  REMARK    GeneRIF: This study demonstrates, for the first time, the presence
            of OXPAT and TIP47 transcripts in rat hepatocytes, as well as their
            up-regulation with lipid accumulation.
REFERENCE   4  (bases 1 to 1944)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   5  (bases 1 to 1944)
  AUTHORS   Fujimoto,Y., Itabe,H., Sakai,J., Makita,M., Noda,J., Mori,M.,
            Higashi,Y., Kojima,S. and Takano,T.
  TITLE     Identification of major proteins in the lipid droplet-enriched
            fraction isolated from the human hepatocyte cell line HuH7
  JOURNAL   Biochim Biophys Acta 1644 (1), 47-59 (2004)
   PUBMED   14741744
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On Jan 6, 2022 this sequence version replaced XM_236783.7.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643299.38081.1,
                                           SRR26643290.31571.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760434,
                                           SAMN12840111 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-58                JAXUCZ010000009.1  1210155-1210212     c
            59-144              JAXUCZ010000009.1  1206029-1206114     c
            145-343             JAXUCZ010000009.1  1204928-1205126     c
            344-426             JAXUCZ010000009.1  1204688-1204770     c
            427-724             JAXUCZ010000009.1  1202594-1202891     c
            725-924             JAXUCZ010000009.1  1200364-1200563     c
            925-1050            JAXUCZ010000009.1  1199733-1199858     c
            1051-1944           JAXUCZ010000009.1  1198336-1199229     c
FEATURES             Location/Qualifiers
     source          1..1944
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q11"
     gene            1..1944
                     /gene="Plin3"
                     /gene_synonym="AABR07066529.1; M6prbp1; Tip47"
                     /note="perilipin 3"
                     /db_xref="GeneID:316130"
                     /db_xref="RGD:1595854"
     exon            1..58
                     /gene="Plin3"
                     /gene_synonym="AABR07066529.1; M6prbp1; Tip47"
                     /inference="alignment:Splign:2.1.0"
     exon            59..144
                     /gene="Plin3"
                     /gene_synonym="AABR07066529.1; M6prbp1; Tip47"
                     /inference="alignment:Splign:2.1.0"
     CDS             76..1392
                     /gene="Plin3"
                     /gene_synonym="AABR07066529.1; M6prbp1; Tip47"
                     /note="mannose-6-phosphate receptor binding protein 1"
                     /codon_start=1
                     /product="perilipin-3"
                     /protein_id="NP_001386258.1"
                     /db_xref="GeneID:316130"
                     /db_xref="RGD:1595854"
                     /translation="MSSNGTEAPAEEVQAAVEDPTMQPSVVGRVANLPLISSTCGMVS
                     AAYTSTKESYPHVRTVCDVAEKGVKTLTTAAVSRAQPILSKLEPQIVTANKYAHQGLD
                     RLQESLPILQQPTEKVLADTKELVSSTVSGAREMVSSSVSGAKDTVATRVTGAVDVTC
                     GAVKSSVDMTKSAMTSGVQSIMGSRVGQMVISGVDRVLVKSEAWADNRLPLTDTELAL
                     IATSPEGADMASLQQQRQERSYFVRLGSLSERLRNQAYEHSLGKLCNVRQSAQDALQQ
                     LAHVLSLMESVKQGVDQRLEEGQEKLHQMWLTWNQKTPQDAEKDPSKPEQVEAQALSV
                     FRDIAQQLQSTCVALGASIQGLPSHVREQAQQARSQVDDLQATFSGIHSFQDLTASVL
                     AQTREHIARARDALEHTVEYVAQNTPAMWLVGPFAPGITEKAPEEK"
     exon            145..343
                     /gene="Plin3"
                     /gene_synonym="AABR07066529.1; M6prbp1; Tip47"
                     /inference="alignment:Splign:2.1.0"
     exon            344..426
                     /gene="Plin3"
                     /gene_synonym="AABR07066529.1; M6prbp1; Tip47"
                     /inference="alignment:Splign:2.1.0"
     exon            427..724
                     /gene="Plin3"
                     /gene_synonym="AABR07066529.1; M6prbp1; Tip47"
                     /inference="alignment:Splign:2.1.0"
     exon            725..924
                     /gene="Plin3"
                     /gene_synonym="AABR07066529.1; M6prbp1; Tip47"
                     /inference="alignment:Splign:2.1.0"
     exon            925..1050
                     /gene="Plin3"
                     /gene_synonym="AABR07066529.1; M6prbp1; Tip47"
                     /inference="alignment:Splign:2.1.0"
     exon            1051..1944
                     /gene="Plin3"
                     /gene_synonym="AABR07066529.1; M6prbp1; Tip47"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agatcggagc tggacttgtt agggaaggtt tcctggcctc gacgacctga ggactttgca
       61 actgctgctg agaccatgtc tagcaatggg acagaagctc ctgctgaaga agttcaggct
      121 gctgtggagg atcctaccat gcagcctagt gtggtgggcc gtgttgccaa cctgcctctc
      181 atcagttcca catgtgggat ggtgagtgct gcctacacct ccaccaagga gagctacccc
      241 cacgtcagga cggtgtgcga cgtggctgag aaaggggtca agaccctcac cacagctgcg
      301 gtcagcaggg cgcaacccat cctgtccaag ctggagcccc agattgtgac agccaacaag
      361 tatgcacacc aagggctgga tagactgcag gagagtctgc ccatcctcca gcagcccact
      421 gagaaggttt tggcggatac taaggaactg gtgtcatcaa cagtgtctgg ggctcgagaa
      481 atggtatcca gctcagtgtc tggtgcaaag gacacagtgg ccactagggt cacaggagca
      541 gtggatgtga cctgtggggc tgtgaaaagc agcgtggaca tgaccaagtc cgcaatgacc
      601 agcggtgttc agtcaatcat gggttcccgc gtgggacaga tggtgattag cggagtggac
      661 agggtgctgg tgaagtcgga ggcctgggca gacaatcgcc tgcccctgac agacacagaa
      721 ctagccctga ttgccacatc tccagagggc gcagacatgg cctccctgca gcagcagaga
      781 caggaaagga gctactttgt caggttgggc tcgctctccg agagactccg caaccaggcc
      841 tatgagcact ccctgggcaa gctgtgtaat gtcaggcaga gtgcacagga cgcgctgcag
      901 cagctcgcac atgtgcttag cctgatggaa tctgtgaaac agggtgtgga ccagaggctg
      961 gaggaggggc aggagaagct gcaccagatg tggctcacct ggaatcagaa gaccccacag
     1021 gatgccgaaa aggacccatc taagccagag caggtggagg cccaggcact cagtgtgttc
     1081 agggacatcg cccagcagct tcagagcacg tgtgtggccc tgggggccag catccaaggc
     1141 ctgccgagcc acgtcaggga gcaggcccag caggcgcgga gccaggtgga tgaccttcag
     1201 gccaccttct ctggcatcca ctccttccag gacctcacag ccagtgttct tgcccaaact
     1261 cgagagcaca tagccagagc ccgagatgcc cttgagcaca ctgtggagta tgtggcccag
     1321 aacactccag ccatgtggct ggtgggcccc tttgctcctg gaatcactga gaaagcccct
     1381 gaagagaagt agggagaagg accagggcca acacctatct gacttgactg cttttcccaa
     1441 cagtcctgtt gcacagcagg tcttccccta ctctgagtct gaatgagacg tgtttaacct
     1501 tttcccatca gtctttttaa agcaaaaata ttttttctag aatctagaat gttctggaaa
     1561 aaattgtttt cctgaaaaaa tgaggatgat gaatagtgat agcacaagcc tgtcatcctg
     1621 ggccagccct gtggtgtaga agcaggaggg tcagttcaaa gcctgactgc cacatagcaa
     1681 attcaatgat agcctagact acgtaagacc ttgtcttgaa gtaaatcagg catagtgaca
     1741 ttccactcca gtttctttcc tgcattcatg gcccagaata gcaagagctt ttctgacaga
     1801 ccctgatacc tggtccaaga atccagcaac tgtgacagga tggagaactg gagtgttgca
     1861 gtcgtttcag atgagaaagt gagagctgag aatccactgt cccttagata atgccttaat
     1921 aaattttacc tgcttcagag acca
//
