LOCUS       XM_236354               3132 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus pleckstrin homology domain containing
            O2 (Plekho2), transcript variant X1, mRNA.
ACCESSION   XM_236354
VERSION     XM_236354.7
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051343.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_236354.8.
            
            On Jan 21, 2021 this sequence version replaced XM_236354.6.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3132
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..3132
                     /gene="Plekho2"
                     /note="pleckstrin homology domain containing O2; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 EST, 2 long SRA reads, 3 Proteins, and 100% coverage
                     of the annotated genomic feature by RNAseq alignments,
                     including 189 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:315764"
                     /db_xref="RGD:1305718"
     CDS             146..1630
                     /gene="Plekho2"
                     /codon_start=1
                     /product="pleckstrin homology domain-containing family O
                     member 2 isoform X1"
                     /protein_id="XP_236354.1"
                     /db_xref="GeneID:315764"
                     /db_xref="RGD:1305718"
                     /translation="MEEESIKEGTEKPRGARTADKAGWIKKSSGGLLSLWKDRYLLLC
                     QAQLLVYENEDEQKCVETVELGSYEKCQDIRTVLKRKHRFILLRSPGNKVSDIKFQAS
                     SGEEKESWIKALNEGINRGKNKAFDEVKVDKTCALEHVTRNRVRGGQRRRPPTRIHLK
                     EVASAASDGLSRLDLDVPDSGQPVFAPLSDISEDQPQEPPQALMPPVKPSPVPETSGA
                     EDSQETPAGERALTPLSESSEANSESQEDAETLAKEDSDFKRLPDSALSEKLKVSWEN
                     PSPEEPSVSERAQLSSSETPEAAPRESKKPPAPPPKILSEKMKACMSGMGDSGPSQSS
                     EGPETTSPGPTQVSVNGVDDGPETASQAVGTAGPAPEDEAASPEVPSWGLPSQFHPRS
                     SSLGDLLRESPQHPRLPKEKLYRAQLEVKVASKQTEKLLNQVLGSEPPPVCAESLLSQ
                     AVEQLRQATQVLQEMRDLEELNQESPGLVQKRKELVTLYRRSAP"
ORIGIN      
        1 cgcccccgaa gtttcttggg ccccgggcgc ccggcgggac agaagacagc aagccgccgc
       61 ccggctgcgc gtagatggag caagcggagc ccgcgcaacg cgggcagcag taagcggcga
      121 agccgccgga cctcacaaac tcgccatgga ggaagagagt ataaaggagg ggaccgagaa
      181 acctcgtgga gcacggactg cagacaaggc tggctggatc aagaagagca gtggggggct
      241 tctgagtttg tggaaagacc gctacttgct tctctgccaa gcccagctgc tggtctacga
      301 gaatgaggac gagcagaaat gtgtagagac ggtggaactt gggagctatg agaagtgcca
      361 ggacatccgt actgtcctca agcggaaaca ccgatttatc ctgcttcgat ccccagggaa
      421 caaggtcagt gacatcaaat tccaggcctc cagtggggaa gaaaaggaat cctggatcaa
      481 agctctcaat gaagggatca accgaggcaa gaacaaggct tttgatgagg taaaagtaga
      541 caagacctgt gccctagagc atgtgacacg gaaccgggta cgtgggggcc agcggcgacg
      601 gccaccaaca agaatccact taaaggaggt agccagtgcg gcttccgatg ggctttcacg
      661 gctggacctg gatgtcccag acagtggaca gccagtgttt gctcctctca gtgacatcag
      721 tgaagaccag ccccaggagc cacctcaggc tctcatgcct cctgtcaagc cttccccagt
      781 accagagacc tctggagctg aggacagcca ggagactcct gcaggagaga gagccctaac
      841 ccctctctca gaaagctctg aggccaattc tgagagccaa gaggatgccg agaccctagc
      901 aaaggaggac agtgacttta agaggctccc ggacagcgca ttgtctgaga aactaaaggt
      961 gagctgggag aaccccagcc cagaggagcc ttctgtttcc gagagggcac agttgtcctc
     1021 ttcagagact ccagaggccg cccccaggga gagtaaaaag ccccctgcac cccctcccaa
     1081 gatcctgtcg gagaagatga aggcctgtat gagtgggatg ggtgattctg gtccatccca
     1141 gagttccgag ggccctgaga ccacatctcc aggccccaca caggtgtctg tgaatggtgt
     1201 ggatgatggt cctgagactg cctcacaggc tgtgggcacc gctggacctg ccccagagga
     1261 cgaagcagca tccccagaag tgccctcctg gggcttgcca tcccagtttc atcctcgctc
     1321 ctcttccctt ggggacctac tcagagaaag ccctcagcat ccacgactgc ccaaggaaaa
     1381 gttgtaccgg gcccagctgg aagtgaaggt ggcttcgaaa cagacagaga aattgttgaa
     1441 tcaggtgctg ggcagtgagc cgccacctgt gtgtgccgag tcattgctca gccaggctgt
     1501 ggagcaactg aggcaggcca cccaggtcct gcaggaaatg agggatttgg aagagctgaa
     1561 ccaagaaagc cctgggctag tgcagaaacg gaaggagctg gtgaccctct acaggagaag
     1621 tgcaccctag gcctgccaag ccccaggcac aaactcacct accccccaag taccctcatc
     1681 tgtcactgcc caaccttgtt atgaaatgag ctacagctca ggttgtagat gcaccactgg
     1741 gtacatcgag tttggccagg acttggtgct cctgatatct tttctactct gccccggcct
     1801 ggggctacct ctccggctcc ctgttctggc ctcttctcta ggctctggca tgggatggag
     1861 catagtcctg tggcctatgt ggttgttgca gactgcccca gggctctggc actgcgcttg
     1921 gagtttccag gatggcacga atctgttctc acccccgaca gtttatattc ctgacttccg
     1981 ggtggagcat ggctgagctg cccgaggtgc ccatcttctg gtcttcaggc ggcttccgct
     2041 tccctccagc catgcctacg tatgagtagc tgtcagggcc ttgggtccag gctgtagtga
     2101 aatgtgaaat ctatcagctg agtgaaatgt ggcctttagc tggagcctaa aaacggataa
     2161 gggtctggat gaaggagcta tttactctgg tttgttttcc tctctgcaaa ccgagagtct
     2221 tctctgcaac atccccaccc ctttggagag ctctgagtag atcagctcag atctcaaggc
     2281 ttccaagggg gaagaggaac tcaggctttc tggtacagtc tctgctcctg ggccagcttc
     2341 tgtccagcct tgcacattct ttttggttct ttttttcgga gctggggacc gaacccaggg
     2401 ccttgcgctt cctaggtaag tgctctacca ctgagctaaa tccccagccc cagccttgca
     2461 cattcttgaa gatgaaaacc ctacagtggc ctgtgttaac ttctgaaaaa cctgtatgaa
     2521 attatcatta atcaaccctt agaggcccca ccccctaccg ctgccttctg tgcctcccag
     2581 atgggattta tctgagtctc tgtggttctt cctcagctgg aatagctctg atagtcaccc
     2641 cttttcttca catgctggag tctgtgacta caatccacct atcaggcccc tggtgggcca
     2701 ccactcccta gagagaagag gagtgttttc tcttccctcc tttcatcccc tcctcccttc
     2761 cccatcgcct ctggctctct gagctaccct gagtctccaa cacattcagc agccagcagg
     2821 aatgagtctg gaacctggct gggggagtga gccctccata ggatctgccc caaggatgca
     2881 tgtgcacttt gtttactgga agagaaagga gggtcacagc aactcgatga tcttttcact
     2941 caccctgttc ccagccacca gctgtgccca ccaaggcctg ccaaccagtg cgggttgatg
     3001 ccttcattac tgtactttcc cttctagcta tgagcagtag gctggggcag agtaaacagc
     3061 agtgtcttga ctcatgaccc cccccacaca cacatacaca cacacacaca catacacaca
     3121 cacatacaca ca
//
