LOCUS       NM_001134523            2801 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus pleckstrin homology domain containing N1
            (Plekhn1), mRNA.
ACCESSION   NM_001134523 XM_001078287 XM_238442
VERSION     NM_001134523.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2801)
  AUTHORS   Kuriyama,S., Tsuji,T., Sakuma,T., Yamamoto,T. and Tanaka,M.
  TITLE     PLEKHN1 promotes apoptosis by enhancing Bax-Bak
            hetro-oligomerization through interaction with Bid in human colon
            cancer
  JOURNAL   Cell Death Discov 4, 11 (2018)
   PUBMED   29531808
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2801)
  AUTHORS   Maeda,A., Uchida,M., Nishikawa,S., Nishino,T. and Konishi,H.
  TITLE     Role of N-myristoylation in stability and subcellular localization
            of the CLPABP protein
  JOURNAL   Biochem Biophys Res Commun 495 (1), 1249-1256 (2018)
   PUBMED   29180010
REFERENCE   3  (bases 1 to 2801)
  AUTHORS   Nishino,T., Matsunaga,R., Jikihara,H., Uchida,M., Maeda,A., Qi,G.,
            Abe,T., Kiyonari,H., Tashiro,S., Inagaki-Ohara,K., Shimamoto,F. and
            Konishi,H.
  TITLE     Antagonizing effect of CLPABP on the function of HuR as a regulator
            of ARE-containing leptin mRNA stability and the effect of its
            depletion on obesity in old male mouse
  JOURNAL   Biochim Biophys Acta 1861 (11), 1816-1827 (2016)
   PUBMED   27616329
REFERENCE   4  (bases 1 to 2801)
  AUTHORS   Sano,E., Shono,S., Tashiro,K., Konishi,H., Yamauchi,E. and
            Taniguchi,H.
  TITLE     Novel tyrosine phosphorylated and cardiolipin-binding protein
            CLPABP functions as mitochondrial RNA granule
  JOURNAL   Biochim Biophys Acta 1783 (6), 1036-1047 (2008)
   PUBMED   18191643
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473968.1.
            
            [WARNING] On Mar 20, 2025 this sequence was replaced by
            NM_001134523.2.
            
            On or before Sep 4, 2008 this sequence version replaced
            XM_238442.4, XM_001078287.1.
FEATURES             Location/Qualifiers
     source          1..2801
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..2801
                     /gene="Plekhn1"
                     /gene_synonym="RGD1311019"
                     /note="pleckstrin homology domain containing N1"
                     /db_xref="GeneID:298694"
                     /db_xref="RGD:1311019"
     exon            1..644
                     /gene="Plekhn1"
                     /gene_synonym="RGD1311019"
                     /inference="alignment:Splign:2.1.0"
     CDS             562..2409
                     /gene="Plekhn1"
                     /gene_synonym="RGD1311019"
                     /note="pleckstrin homology domain containing, family N
                     member 1"
                     /codon_start=1
                     /product="pleckstrin homology domain-containing family N
                     member 1"
                     /protein_id="NP_001127995.1"
                     /db_xref="GeneID:298694"
                     /db_xref="RGD:1311019"
                     /translation="MGNSHCVPQTPRRLRASFSRKPSLKGNREDSARKLAGLFGTEAR
                     PDGDTAANKIFHYIPGTDILGPENHPENLEQPFLSVFKKGWRRTPVRNLGKVVHYSKV
                     QLRFQHSQDISDCYLELFPSHLYFQAHGSEGLTFQGLLPLTELSICPIDGSREHAFQI
                     TGPLPAPLLVLCHSEAELSHWLYHLEKQMALLGLRQCHSAPPQGSLGDKLPWTQLWRA
                     HGCEPMNSAICASRVKLQHLPSQEQWDRLLVLYPASLAIFSEEPEGLNFKGELPLSAI
                     HINLEEKEKEIRSFLIEGRLINTIRVVCASYEDYSQWLLCLRTVSHRDGAHLLPGPES
                     FPGLQRPTQVLGRGRGSLSSNGRTSRKLECPVFPTSQSLPEPSVPTTIGVPAHPVPNQ
                     TNSNCVSTGQTKVELRHSGSSQFPRGKAQREVSGSTAPLPLHLDLTKMSVLNLDSGPE
                     AQDCSPDIPHSPLYADPYTPPAIAHHKITDIQGLDEFLCAVQTSPGPELSSPFPSVSV
                     SVPVSDSNSGISSSPRPLGSHLLSKKGALQSRASQRHRGSIKSRAPQPSDFPQLGKGS
                     YFLNLMPESSLTPLLDEEAPIWNKTSSPSHQKWSHPRKPAVEGGFIQWI"
     exon            645..744
                     /gene="Plekhn1"
                     /gene_synonym="RGD1311019"
                     /inference="alignment:Splign:2.1.0"
     exon            745..891
                     /gene="Plekhn1"
                     /gene_synonym="RGD1311019"
                     /inference="alignment:Splign:2.1.0"
     exon            892..972
                     /gene="Plekhn1"
                     /gene_synonym="RGD1311019"
                     /inference="alignment:Splign:2.1.0"
     exon            973..1045
                     /gene="Plekhn1"
                     /gene_synonym="RGD1311019"
                     /inference="alignment:Splign:2.1.0"
     exon            1046..1170
                     /gene="Plekhn1"
                     /gene_synonym="RGD1311019"
                     /inference="alignment:Splign:2.1.0"
     exon            1171..1284
                     /gene="Plekhn1"
                     /gene_synonym="RGD1311019"
                     /inference="alignment:Splign:2.1.0"
     exon            1285..1365
                     /gene="Plekhn1"
                     /gene_synonym="RGD1311019"
                     /inference="alignment:Splign:2.1.0"
     exon            1366..1441
                     /gene="Plekhn1"
                     /gene_synonym="RGD1311019"
                     /inference="alignment:Splign:2.1.0"
     exon            1442..1590
                     /gene="Plekhn1"
                     /gene_synonym="RGD1311019"
                     /inference="alignment:Splign:2.1.0"
     exon            1591..1731
                     /gene="Plekhn1"
                     /gene_synonym="RGD1311019"
                     /inference="alignment:Splign:2.1.0"
     exon            1732..1878
                     /gene="Plekhn1"
                     /gene_synonym="RGD1311019"
                     /inference="alignment:Splign:2.1.0"
     exon            1879..2019
                     /gene="Plekhn1"
                     /gene_synonym="RGD1311019"
                     /inference="alignment:Splign:2.1.0"
     exon            2020..2247
                     /gene="Plekhn1"
                     /gene_synonym="RGD1311019"
                     /inference="alignment:Splign:2.1.0"
     exon            2248..2801
                     /gene="Plekhn1"
                     /gene_synonym="RGD1311019"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccctgacttc ggcttgggtg agggttggcc cagaaagaag agaagctgag agaaggtcct
       61 ggcctccctt tatgtgaagt tgcactaatt gagcagctga gagtgagcac acctacagtc
      121 accaatgact cagacagctg ggattcatgt ggaaacagga tgtgtgcacc ccggcagggg
      181 aggggcaact gggaggaaga atcccagcgt tcatagaagt ccaatgtcta gacactccag
      241 tctgaataca ggtgttcagg gtgtatacag accaggtcct tctgaccagg tctatacaga
      301 gtgctgagaa gagggctcca ggtccaatca ggaaatagct accctacccc taggctgact
      361 gccttgggcc tagaaaacct gggctctcac tggaaggttt ccctcaaaag gggccaatcc
      421 gggcccagag aggagcctcc tccagcccca gggtaggggc agggcgtcct gtggctacgc
      481 ccatcagcgg gaggtgttag cagacggagc gaaggaccca gacctgtcga cctgccctgc
      541 ccaagctagc agctgccatc catggggaac agccactgcg tccctcagac ccccaggagg
      601 ctacgggcct ccttttccag aaaaccctcg ctcaagggaa acagagaaga cagcgccagg
      661 aagctggctg gcctgtttgg caccgaggct aggcctgatg gggacaccgc agctaacaag
      721 atcttccact acatccctgg gacggacatc ctgggcccag aaaatcatcc agaaaacctg
      781 gaacagccat tcctgagtgt attcaaaaaa gggtggcgga ggacacctgt gaggaaccta
      841 ggcaaggtgg tgcactattc caaggttcag ctgcggttcc agcacagcca ggacatcagt
      901 gactgctatc tggaactgtt cccctcccac ctgtacttcc aggcccatgg ttctgaagga
      961 cttacattcc aggggctgct accactgacg gaattgagca tctgcccgat tgatgggtcc
     1021 agagagcatg ccttccagat tacaggccca ctgcctgccc cactccttgt tctctgccac
     1081 agtgaggccg agctcagcca ttggctctac cacctggaaa agcaaatggc tctcctgggt
     1141 ctgcggcaat gccactcagc acccccacag ggttctctag gagataaact cccctggacc
     1201 cagctatggc gagcgcacgg gtgtgaaccc atgaacagcg caatctgtgc ctcaagggtc
     1261 aagctgcagc atctgccctc ccaggagcag tgggaccggc ttctggtact gtacccagca
     1321 tccctggcca tcttctctga ggagccagaa ggccttaact ttaaggggga gcttccacta
     1381 agtgccatcc atatcaactt agaagagaag gaaaaagaga tccgctcctt tctcatcgaa
     1441 ggccgtctca tcaacaccat ccgagtggtg tgtgccagtt atgaggatta cagtcaatgg
     1501 ctgctgtgcc tcaggacggt ctctcacagg gatggggccc acctgctgcc tggcccagag
     1561 agtttcccag gactacagag acccacacag gttttaggta gaggccgagg ttcactctct
     1621 tccaatggac gaaccagccg gaaattagag tgtccagtgt tccctaccag ccaatccctc
     1681 cctgagccct cagtgccaac caccataggt gtccctgccc atcctgtgcc taaccagacc
     1741 aactctaact gtgtcagcac tggccaaacg aaggtagagc tgaggcacag tggcagtagc
     1801 cagttcccca ggggcaaagc tcaaagagaa gtatctggct caactgcccc actgcccctg
     1861 cacctggacc tgacgaagat gagtgtcctg aacctagata gtggcccaga ggctcaggat
     1921 tgctctccag acattccaca ctccccgctc tatgctgatc cctacacacc accagctata
     1981 gctcaccaca agattacaga catccaaggc ctggatgagt tcctctgtgc agtacagaca
     2041 tcacctggac ctgaactatc aagcccgttc ccctcagtct ctgtgtctgt gcctgtctct
     2101 gactccaact ctggaatctc cagctccccc cggcctctgg gctcacactt gctctccaag
     2161 aaaggagccc tgcagtccag agcttcccag agacaccggg gttccatcaa gagcagggcc
     2221 ccacagccct cagacttccc tcagcttgga aaggggtcct acttcttaaa cctgatgcct
     2281 gagtcgtctc tgactcccct actagatgaa gaggctccta tctggaacaa gacttcctct
     2341 ccctcccacc agaagtggtc acatcccagg aagcctgcgg tggaaggggg attcatccag
     2401 tggatctgat ggcccccgag tgagctgctg cttctcaaaa aacacaaaca gccagcacca
     2461 accgggataa gagtatgcag ttcggccagt cctttgactt atattaaata caccagggcc
     2521 taaccccatc aggtcgaggg tgtttctaga attttgagga tagaggcacc tctcaccagg
     2581 ctctagctac tcagctttag cagttggaac aaatgaaagg aggtaaccct aggaacgaac
     2641 cagtgaggga catcagtaag attctgtaca accccagaag ctatacctct agggggagag
     2701 gtgggggtgc tagtgcaggt ctttacttag aagtggggaa cagcatgcgt gtgaaataca
     2761 gagcactgaa aaagtcaggt tgtcaaaccc agcctgtgaa g
//
