LOCUS       NM_001191767            3268 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus pleckstrin homology and RUN domain containing M2
            (Plekhm2), mRNA.
ACCESSION   NM_001191767 XM_233611
VERSION     NM_001191767.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3268)
  AUTHORS   Pu,J., Schindler,C., Jia,R., Jarnik,M., Backlund,P. and
            Bonifacino,J.S.
  TITLE     BORC, a multisubunit complex that regulates lysosome positioning
  JOURNAL   Dev Cell 33 (2), 176-188 (2015)
   PUBMED   25898167
REFERENCE   2  (bases 1 to 3268)
  AUTHORS   Ohlson,M.B., Huang,Z., Alto,N.M., Blanc,M.P., Dixon,J.E., Chai,J.
            and Miller,S.I.
  TITLE     Structure and function of Salmonella SifA indicate that its
            interactions with SKIP, SseJ, and RhoA family GTPases induce
            endosomal tubulation
  JOURNAL   Cell Host Microbe 4 (5), 434-446 (2008)
   PUBMED   18996344
REFERENCE   3  (bases 1 to 3268)
  AUTHORS   Jackson,L.K., Nawabi,P., Hentea,C., Roark,E.A. and Haldar,K.
  TITLE     The Salmonella virulence protein SifA is a G protein antagonist
  JOURNAL   Proc Natl Acad Sci U S A 105 (37), 14141-14146 (2008)
   PUBMED   18787122
REFERENCE   4  (bases 1 to 3268)
  AUTHORS   Boucrot,E., Henry,T., Borg,J.P., Gorvel,J.P. and Meresse,S.
  TITLE     The intracellular fate of Salmonella depends on the recruitment of
            kinesin
  JOURNAL   Science 308 (5725), 1174-1178 (2005)
   PUBMED   15905402
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Jul 17, 2010 this sequence version replaced XM_233611.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643294.23579.1,
                                           SRR26643293.31336.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760389,
                                           SAMEA5760476 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-60                JAXUCZ010000005.1  159261384-159261443 c
            61-167              JAXUCZ010000005.1  159239583-159239689 c
            168-277             JAXUCZ010000005.1  159239286-159239395 c
            278-377             JAXUCZ010000005.1  159238673-159238772 c
            378-465             JAXUCZ010000005.1  159238118-159238205 c
            466-652             JAXUCZ010000005.1  159234332-159234518 c
            653-712             JAXUCZ010000005.1  159232718-159232777 c
            713-938             JAXUCZ010000005.1  159229578-159229803 c
            939-1796            JAXUCZ010000005.1  159228238-159229095 c
            1797-1866           JAXUCZ010000005.1  159228044-159228113 c
            1867-1957           JAXUCZ010000005.1  159227819-159227909 c
            1958-2022           JAXUCZ010000005.1  159227501-159227565 c
            2023-2111           JAXUCZ010000005.1  159227085-159227173 c
            2112-2244           JAXUCZ010000005.1  159226383-159226515 c
            2245-2435           JAXUCZ010000005.1  159225971-159226161 c
            2436-2501           JAXUCZ010000005.1  159225656-159225721 c
            2502-2661           JAXUCZ010000005.1  159224810-159224969 c
            2662-2841           JAXUCZ010000005.1  159224410-159224589 c
            2842-2958           JAXUCZ010000005.1  159224216-159224332 c
            2959-3268           JAXUCZ010000005.1  159223300-159223609 c
FEATURES             Location/Qualifiers
     source          1..3268
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..3268
                     /gene="Plekhm2"
                     /note="pleckstrin homology and RUN domain containing M2"
                     /db_xref="GeneID:313667"
                     /db_xref="RGD:1307005"
     CDS             1..3096
                     /gene="Plekhm2"
                     /note="pleckstrin homology domain containing, family M
                     (with RUN domain) member 2"
                     /codon_start=1
                     /product="pleckstrin homology domain-containing family M
                     member 2"
                     /protein_id="NP_001178696.1"
                     /db_xref="GeneID:313667"
                     /db_xref="RGD:1307005"
                     /translation="MEPREVKDRILENISLSVKKLQSYFAACEDETPAIRNHDKVLQR
                     LCEHLDHALLYGLQDLSSGYWVVVVHFTRREAIRQIEVLQHVATNLGRSRAWLYLALN
                     ENSLESYLRLFQENLGLLQKYYVRNALVCSHDHLTLFLTLVSGLEFIRFDLDLDAPYL
                     DLAPYMPDYYKPQYLLDFEDRLPSSVHGSDSLSLNSFNSVTSTNLEWDDSAIAPSSED
                     YDFGDVFPAVPSVPSTDWEDGDLTDTISGPRSTASDLTSSKASTKSPTQRHNPFNEEQ
                     AESASSETTPVHTTSQEKEEAQAPDQPDACTELEVIRVTKKKKIGKKKKTKLDEEASP
                     LHPNCSQQKCGRQGDGDGLVGTPGLARNCSDTILASPQEQGEGPGSTAGSCEHSELSQ
                     MGLLIPEMKDTSMECLGQPLSKVIDQLHGQLDPSTWCSRVEPPDQSFRTGSPGEAPEK
                     PPFCDFSEGLPAPMDFYRFTVESPSTVAPGGGHHDPPGSSQPLHVPGSPAPALQEEEG
                     GRGEGQTSQPLEDQQGKEIQEPEPQEPDSQLPLVSQEPGPEPVSQPEPGTQETLCKLK
                     GDQPSPCLSSAEDSGVDEGQGSPSEMTHPSEFRVDNNHLLLLMIHVFRENEEQLFKMI
                     RMSTGHMEGNLQLLYVLLTDCYVYLLRKGATEKPYLVEEAVSYNELDYVSVGLDQQTV
                     KLVCTNRRKQFLLDTADVALAELFLASLKSAMIKGCREPPYPSVLTDATMERLALAKF
                     VAQESKCEASTVTVHFYGLVHWEDPMEEALGPVPCQCSPAEGTITKEGMLHYKASTSY
                     LGKEHWKACFVVLSNGILYQYPDRTDVIPLLSVNMGGEQCGGCRRSNTTDRPHAFQVI
                     LADRPCLELSADSEAEMADWMQHLCQAVSKGVIPQGIAPSPCIPCCLVITEDRLFTCH
                     EDCQTSFFRSLGTARLADITAISTELGKEYCVLEFSQDSPQLPKPWVIYMSCTSELDR
                     FLTALSSGWKAIYQVDLPHKAIHEASIKQKFEDALSLIHSAWQRSDSLCRGRASRDPW
                     C"
     exon            1..60
                     /gene="Plekhm2"
                     /inference="alignment:Splign:2.1.0"
     exon            61..167
                     /gene="Plekhm2"
                     /inference="alignment:Splign:2.1.0"
     exon            168..277
                     /gene="Plekhm2"
                     /inference="alignment:Splign:2.1.0"
     exon            278..377
                     /gene="Plekhm2"
                     /inference="alignment:Splign:2.1.0"
     exon            378..465
                     /gene="Plekhm2"
                     /inference="alignment:Splign:2.1.0"
     exon            466..652
                     /gene="Plekhm2"
                     /inference="alignment:Splign:2.1.0"
     exon            653..712
                     /gene="Plekhm2"
                     /inference="alignment:Splign:2.1.0"
     exon            713..938
                     /gene="Plekhm2"
                     /inference="alignment:Splign:2.1.0"
     exon            939..1796
                     /gene="Plekhm2"
                     /inference="alignment:Splign:2.1.0"
     exon            1797..1866
                     /gene="Plekhm2"
                     /inference="alignment:Splign:2.1.0"
     exon            1867..1957
                     /gene="Plekhm2"
                     /inference="alignment:Splign:2.1.0"
     exon            1958..2022
                     /gene="Plekhm2"
                     /inference="alignment:Splign:2.1.0"
     exon            2023..2111
                     /gene="Plekhm2"
                     /inference="alignment:Splign:2.1.0"
     exon            2112..2244
                     /gene="Plekhm2"
                     /inference="alignment:Splign:2.1.0"
     exon            2245..2435
                     /gene="Plekhm2"
                     /inference="alignment:Splign:2.1.0"
     exon            2436..2501
                     /gene="Plekhm2"
                     /inference="alignment:Splign:2.1.0"
     exon            2502..2661
                     /gene="Plekhm2"
                     /inference="alignment:Splign:2.1.0"
     exon            2662..2841
                     /gene="Plekhm2"
                     /inference="alignment:Splign:2.1.0"
     exon            2842..2958
                     /gene="Plekhm2"
                     /inference="alignment:Splign:2.1.0"
     exon            2959..3268
                     /gene="Plekhm2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggagcctc gggaggtgaa ggaccgaatc ctggagaaca tctcgctgtc ggtgaagaag
       61 ctgcagagct acttcgcagc atgcgaggac gagacccctg ccatccggaa ccacgacaag
      121 gtcctgcagc gcctgtgtga gcacttggac cacgccctgt tgtacggatt gcaagacctg
      181 tcctctggct actgggtggt cgtggtccat ttcacccgca gagaggccat caggcaaatt
      241 gaagtgctac agcatgtggc caccaacctg gggcgaagcc gcgcctggct ctacctggct
      301 ctcaatgaga attccttgga gagctacctt cgcctgttcc aggagaacct gggtctgtta
      361 cagaagtact atgtcaggaa tgccctggtc tgcagccacg atcacttgac tctcttcctg
      421 accttggtgt ctgggttgga gtttattcgg ttcgacctgg atctggatgc cccgtactta
      481 gacctggccc catatatgcc tgactactat aaacctcagt acctgctgga ctttgaagac
      541 cgccttccca gctcagtcca cggctcagac agcctgtccc tgaactcctt caactctgtc
      601 acctccacca acctggaatg ggatgacagc gcaattgccc catctagtga ggattatgat
      661 tttggagatg tgtttccagc agtgccgtct gtacccagca cagactggga agatggagac
      721 ctcacagata ccatcagtgg tccccgctct actgcttcag acctgaccag tagcaaggca
      781 tccaccaaga gccccaccca gcgccacaac cccttcaacg aggagcaggc ggagagcgcg
      841 tcatctgaga ccacccccgt gcacactacc tctcaggaga aggaagaggc ccaggcccca
      901 gaccagccag atgcttgtac agagcttgaa gttatcaggg tcaccaagaa gaagaagatt
      961 ggcaagaaga aaaagaccaa gctggatgag gaagcaagcc cactgcaccc caactgtagc
     1021 cagcagaagt gcggtcggca gggggacggt gacggacttg tgggcacccc aggcctggcg
     1081 cggaactgtt cggacaccat acttgcctct ccacaggagc aaggggaagg gcccggcagt
     1141 accgccggga gctgtgagca ctcagagctc agccagatgg gtttgctgat ccccgagatg
     1201 aaggacacct ccatggagtg cctaggacag cccctgagca aggtcatcga ccagcttcat
     1261 ggccagctgg accctagcac ctggtgctcc cgtgtcgagc ccccggatca gtcctttcgg
     1321 accggctctc ccggggaggc cccggagaaa ccgccatttt gcgactttag tgaggggctt
     1381 ccagccccca tggacttcta ccggtttaca gtcgagagtc caagtactgt tgcaccaggt
     1441 ggcggccacc atgaccctcc agggtctagc caaccgctgc atgttcctgg tagccctgcg
     1501 cctgctctcc aagaagaaga gggaggaaga ggagagggac agacatctca gcccctagag
     1561 gaccagcaag ggaaggagat tcaggagcca gagcctcagg aaccagacag ccagttgccg
     1621 ctggtcagcc aggagcctgg gcctgaacct gtgtcccagc ctgaacctgg aacccaggaa
     1681 actctttgca agctcaaggg agaccagccc agtccttgtc tgagcagtgc tgaggactcc
     1741 ggggtagacg agggccaggg tagcccctca gagatgacgc acccctcaga gttcagagta
     1801 gacaacaacc acttgctcct actcatgatt cacgtctttc gagaaaatga agaacagttg
     1861 ttcaaaatga tccggatgag cacagggcac atggagggta acctacagct gctctacgtg
     1921 ctactcacag actgctatgt ctacctgctt cggaaagggg ccacagaaaa gccatacctg
     1981 gtggaagagg ctgtttctta caatgaactt gactatgtgt cggttggcct ggaccaacag
     2041 actgtcaagc tggtgtgcac caaccgcagg aagcagtttc tgctggacac ggccgacgtg
     2101 gccctggctg agctgttctt ggcgtctctg aagtcagcca tgatcaaagg ttgccgggaa
     2161 ccaccctacc ccagcgtctt gactgatgcc accatggaga ggctggcgct ggcaaaattt
     2221 gtcgcccagg aatccaaatg tgaggcatcc actgtgaccg tgcacttcta cggacttgta
     2281 cactgggagg accccatgga agaggccctg ggccctgttc cttgccagtg ctcacccgct
     2341 gagggcacga tcaccaaaga aggcatgctc cactataagg ccagcacctc ctacctgggc
     2401 aaagagcact ggaaggcctg cttcgtggtg ctcagcaatg ggatcctcta ccagtatcct
     2461 gatcgcactg acgtcatccc cctgctctcc gtgaacatgg gtggggagca gtgcggtggc
     2521 tgccggagat ccaacaccac ggatcggccc cacgccttcc aggtcattct ggctgaccgg
     2581 ccttgcctgg agctaagcgc cgacagtgag gccgagatgg cagactggat gcaacatctt
     2641 tgccaggccg tatccaaagg agtcataccc cagggcatag ctcccagccc ctgtatccct
     2701 tgctgtctgg tgatcacgga ggaccgcctc ttcacatgcc acgaagattg ccaaaccagc
     2761 ttcttccgct ccctgggcac agccagactg gcggacatca ctgctatctc cactgagtta
     2821 ggcaaggagt actgtgtcct ggagttctcc caggatagcc cccagctgcc gaagccctgg
     2881 gtcatctaca tgagctgcac ttccgagttg gaccggttcc tgaccgccct gagctctggg
     2941 tggaaagcca tctaccaggt agaccttcct cacaaggcaa tccatgaagc ttccatcaag
     3001 cagaaatttg aagatgccct gagcctcatc cacagcgcct ggcagcggag cgacagcctc
     3061 tgccgcggca gggcctcccg ggacccctgg tgctgaggct gggcaaccct gtgggcaggc
     3121 gggaaggagg tgtgctgacc agcctctgca ctgtggtgtg ccgccatggc gtttcagagc
     3181 caggggccaa caacccactc ctgccttggg gtggcagaac cacttagtgt ggctggcgtg
     3241 agagaggaat tcagtcagtg cctggcac
//
