LOCUS       XM_039098211            4555 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus pleckstrin homology and RhoGEF domain
            containing G4 (Plekhg4), transcript variant X1, mRNA.
ACCESSION   XM_039098211
VERSION     XM_039098211.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051354.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039098211.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4555
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4555
                     /gene="Plekhg4"
                     /note="pleckstrin homology and RhoGEF domain containing
                     G4; Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 1 Protein, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     5 samples with support for all annotated introns"
                     /db_xref="GeneID:307796"
                     /db_xref="RGD:1310790"
     CDS             630..4325
                     /gene="Plekhg4"
                     /codon_start=1
                     /product="puratrophin-1 isoform X1"
                     /protein_id="XP_038954139.1"
                     /db_xref="GeneID:307796"
                     /db_xref="RGD:1310790"
                     /translation="MEGPLECGDVSLDYQGHAADGRRFVVCSFRNTGKEEEPAHQIQA
                     MDPRLSRPAVGATQGIGLQGDFLSKKPQSLPDQSAADRSGGNQRSILGAPQAQSEEPA
                     FSEMENCLCPGSSHLNLTQGENDHRGGGLIGDPEPGRALPAGFSPLLEMSSKLPEADP
                     SGSSFPRPADCLLARDLTWELLASGMAALPGSLGGLMRWRKWPGKARIHSLLSTGTRD
                     IEGRAVLLLCAHSPAWLHPKCNSHELLSLLFYLRGIPRPEVQALGLTVLVDARICPPS
                     SALTWGLSQLQEASPGSVQQLLLVGKMPEDMPVGLQAKQLASHQSLLTHIPNMELPTS
                     LGGCLSYCHQAWLDFRMRLETLQQSCQVACALLQGVIDSMKAMRQPLESGEVGELLQQ
                     AQSLMQQVLESPQLSWLQSQGSLELAWLKQGMPQVALSPDYRSAVDKADELYGQVDEL
                     LHRLTLKSNQRIRALELLQALEAQEGVLCQIEVWLQEVGWPGLEEPGEPSLDMLLQAQ
                     GPFQELDLVAQEQVKQGEKLLQPLVGWEAAELGPTGKRFLALRSQLMEFSRALAQRRQ
                     RLADAEKLFQFFKQASTWTEEGQRVLTELEQETPEVVLQRLQLHWSKHPDLPPAHFRK
                     MWALATGLGSEGIRQECRWAWAQCQDTWLALDQKREAALKPQSMNSTATLYVRRAPAI
                     PTIPPLRKSYSFDQNLGKHLGDASNRGHCAATVTDCHRPEARGGIRPRSSPSVPLSGS
                     SDFRSPNRLQLVLAEMVATEREYVRALDYTIQNYFPELDRSDVPQGLRGQRAHLFGNL
                     EKLRDFHFHFFLRELEACTRHPPRVAHAFLRHRVQFGMYALYSKNKPRSDALMSNYGH
                     TFFKEKQQALGDHLDLASYLLKPIQRMSKYALLLQELARACGGPAQELGALQAAQSLV
                     HFQLRHGNDLLAMDAIQGCDVNLKEQGQLVRQDEFTVRAGHHKSCRRVFLFEELLLFS
                     KPRRGPAGVDIFTYKRSFKMADLGLTECCGESKLRFEIWFRRRKARDLFVLQASDVAT
                     KQAWTADISRLLWRQAVHNKEVRMAEMASMGVGNKAFWDIAPSEEAINDRNINYVLKR
                     RDVRSRASIAVAPFDYDNPYLGALASLPGDRASCSVLGSLNLHLYRDPALLGVHWSLL
                     PPNFPEEASLDTEVDLGSQPSLTPEDSEVSSQCPSASGSSGSDSSCVSGQTMGRGLED
                     LSCETTTLDSGHPCYFQESEEMDDCLG"
ORIGIN      
        1 ttccggacga gcctgtgatt cggtcctcca gaccctagag ggcgccgcgt ccacagcggc
       61 cttgcggccc ttcgagccac cagaaggtgg cgcccttgga ttctgggcgg cctcgcggta
      121 tccatcgttg aggctgtggt gcgtttgttc ttcgttagtt cgagggctct gtagtcttct
      181 ggcttcagag ttccctacag cgcgtcccag gggtgtgagt gtgtgggtga cccgtgaggg
      241 gccgggagca cgggtacagg cacctagggc agggcctggc aggttgggct ggagcgcaga
      301 gcggcgcgtg agtctgctaa gcctggggtg aaggtgtgcc tgaacatagg gccaccccgt
      361 agaggctcat ggaagtgtaa gccggcctta ggcccaaagg agactctgta tcttcagtca
      421 ccagactgga ctactttagc agccatgcgt ccggggactc ggtacccagc ctagcacttc
      481 ctactgccta gtgttcccgg cttacctgcc cgcggagtct tgccccacca tcttcaaacc
      541 agttcctgga taagctgaag tctcctttta catcaaggcc taacccgtta cctatttgtc
      601 cagagcaagc ccactcttac cagggagtga tggaagggcc tcttgagtgt ggggatgtct
      661 ccctagacta ccagggccat gctgcagatg ggaggaggtt tgttgtgtgc agtttcagga
      721 acaccgggaa ggaggaggaa cctgctcacc agatacaggc tatggaccca agactttcaa
      781 gaccagcagt aggggcaacc caaggcatag ggctacaagg agatttctta tccaagaagc
      841 ctcaatcact tccagatcaa agcgctgcag ataggtcagg gggcaaccag aggagcatat
      901 taggagcccc ccaagcccag tcagaggagc cagccttctc tgaaatggaa aactgtttgt
      961 gtcctggttc ctcccacctc aacctgacac agggtgagaa tgaccatcga gggggaggat
     1021 tgatagggga cccagagcca ggcagagcgc tgccagctgg ctttagccct ttattggaga
     1081 tgtcctcaaa gctaccggag gcagacccta gtggatccag cttccctagg cctgctgact
     1141 gcctcctagc tcgagatctc acctgggagc tactggccag cggcatggct gccctcccag
     1201 gtagtttagg aggactgatg aggtggagga agtggcctgg taaggccagg attcattctc
     1261 tcctctccac agggacacgg gacatagaag gccgagcagt gctacttttg tgtgcccaca
     1321 gcccagcttg gcttcatccc aagtgtaata gccatgagct gctgagtctt ctgttctacc
     1381 tacgaggcat ccccaggcct gaggtgcagg ctctgggact gaccgtacta gtggatgccc
     1441 gaatctgccc accgagctct gccctcacct ggggcctcag ccaactacaa gaagcatccc
     1501 cagggtctgt acagcaactg ctgctggttg ggaagatgcc cgaggacatg cccgtggggc
     1561 tccaggccaa gcagctggct tctcatcaga gcctcctcac ccacattcct aacatggagt
     1621 tgcctacttc actaggagga tgcctgtctt actgccacca agcctggctg gatttccgga
     1681 tgcgtctgga aaccctacag cagagttgtc aggtggcttg tgccctgctt cagggcgtca
     1741 ttgacagtat gaaggctatg cggcagccct tggagtctgg agaagttggt gagctgctac
     1801 agcaggcaca gtccctcatg cagcaggtat tagagtcacc acagttgtca tggttacaaa
     1861 gtcagggaag cctggagctc gcatggttga aacaagggat gccacaggtg gccctgagcc
     1921 ccgattacag gtctgcagta gacaaggctg atgagttgta tggtcaagtg gatgaactgt
     1981 tgcatcggct aaccctgaag agcaaccagc gaatccgggc cctagagctc ctccaagcac
     2041 tggaagccca ggagggtgtg ctgtgccaga ttgaagtgtg gctacaggag gtgggctggc
     2101 cagggctgga ggaaccaggg gagccctcac tggacatgct actccaggcc cagggccctt
     2161 ttcaagagct ggacctggtt gcccaggaac aggtcaagca aggggagaag ttactgcagc
     2221 cattagttgg ctgggaggct gctgaactgg ggcccactgg aaagcgcttt ctggccctga
     2281 gatcccagct gatggaattt tccagagctt tggcccagcg gcgccagcgg ttggcagatg
     2341 ctgagaagct gtttcagttc tttaagcagg cctcaacatg gacggaggaa gggcagcggg
     2401 tgctgacaga gctggagcag gagaccccgg aggttgtgct gcagcgactg cagctgcact
     2461 ggagcaaaca ccctgacttg cctcctgccc acttccggaa aatgtgggct ctggctacag
     2521 gcctaggctc agaaggcatt cgccaggaat gtcgctgggc ctgggcacag tgccaggaca
     2581 cctggctggc tctggatcag aagcgtgagg ctgcactaaa gccacaatca atgaatagca
     2641 cagctacttt gtatgtcagg cgggctcctg ctatacccac catccctcca ctgaggaagt
     2701 cctacagctt tgatcagaat ctggggaagc atcttggaga tgcttccaat cgtggccact
     2761 gtgcagccac tgttactgac tgccacagac ctgaggccag aggaggcatc cggcccaggt
     2821 catcaccttc tgtgcctctg tcaggcagtt ctgacttcag gagccccaac aggctacagc
     2881 tagtattggc ggagatggtg gccacagagc gtgagtatgt ccgggccctt gactacacca
     2941 tacagaacta cttccctgag ttagatcggt ccgatgtgcc ccagggcctc cgtggccagc
     3001 gtgcacacct ctttggcaac cttgaaaagc ttcgggattt ccacttccat ttcttcctgc
     3061 gtgagctaga ggcttgcacc cggcacccac ctcgagtggc tcatgccttc ctgcgccaca
     3121 gggtgcagtt tggaatgtat gcactctaca gcaagaataa acctcggtct gatgccctga
     3181 tgagcaacta tggccacacc ttcttcaagg agaagcagca ggcactggga gaccacctgg
     3241 acttggcttc ctacctgcta aagcccatcc agcgcatgag caagtatgcc ttactgctgc
     3301 aggagctggc gagggcctgt gggggtccag cacaagagct gggtgccctt caggcagccc
     3361 agagccttgt gcatttccag ctgagacatg gcaatgacct gctagccatg gatgccattc
     3421 agggctgtga cgttaacctc aaggagcagg ggcagttggt acgacaggat gagttcacag
     3481 tgcgggctgg gcaccacaag tcctgtcgtc gcgttttcct gtttgaggag ctgctgctct
     3541 tcagcaaacc tcgacgtggg cctgcaggtg ttgacatatt cacctacaag cgttccttca
     3601 aaatggcaga cctcggcctc acggagtgct gtggggaaag taaactgcgc ttcgagatct
     3661 ggttccgacg tcgcaaggcc agggacctgt ttgtgcttca ggcttccgat gtggccacca
     3721 aacaagcctg gacagctgat atctcccgtc tcctctggag gcaggctgta cacaacaagg
     3781 aggtgcgcat ggctgagatg gcatccatgg gtgtggggaa caaagccttc tgggacattg
     3841 cccccagtga ggaggctatc aatgaccgca acatcaacta tgtgctgaaa agacgagatg
     3901 ttcgctctag ggcctccatt gctgtggccc catttgacta tgacaaccct tatctgggtg
     3961 ccttggcctc cctacctgga gaccgtgcct cttgctctgt tctggggtct ctcaatctgc
     4021 acctgtacag agatccagct cttctgggtg ttcactggtc cttgcttcca cccaacttcc
     4081 cagaagaagc atcactagat actgaggtgg acttgggcag ccagccttct ttgactcctg
     4141 aggactcaga ggtctcatcc cagtgcccat cagccagtgg ctctagtggt tctgacagca
     4201 gctgtgtgtc ggggcagacc atgggcagag gccttgaaga cttgtcctgt gaaacaacaa
     4261 ccctggactc aggccatccc tgctacttcc aggagagtga ggagatggat gactgtcttg
     4321 ggtgaggagg gaagtcctct ggagtactaa tttcaaaggc actgttcttt ctttacttga
     4381 cccagctttc tcaagccagc taggttgctg ctcctgtcca tctagattgc cagctccctc
     4441 tggtctatga atggtaatgt cctaggtgtg cagtttttca tgcgcccact cagaatggaa
     4501 ctaggagttt ccctttttgt acaggattag actgtgaact ccagaagata ggaat
//
