LOCUS       XM_017594465            5741 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus pleckstrin homology and RhoGEF domain
            containing G3 (Plekhg3), transcript variant X1, mRNA.
ACCESSION   XM_017594465
VERSION     XM_017594465.2
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051341.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_017594465.3.
            
            On Jan 21, 2021 this sequence version replaced XM_017594465.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5741
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..5741
                     /gene="Plekhg3"
                     /note="pleckstrin homology and RhoGEF domain containing
                     G3; Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 25 ESTs, 1 long SRA read, 2 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 6 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:314249"
                     /db_xref="RGD:1308089"
     CDS             953..5152
                     /gene="Plekhg3"
                     /codon_start=1
                     /product="pleckstrin homology domain-containing family G
                     member 3 isoform X1"
                     /protein_id="XP_017449954.1"
                     /db_xref="GeneID:314249"
                     /db_xref="RGD:1308089"
                     /translation="MGALLRKANLPEVTVPGSDARMPVSTALHQDGSQERPPSLMSTT
                     SSSGSSRDSHSAMEEPTGSEASAQNGTGSPWGRHIPNSNNNSSSWLNMKGPLSPFNGR
                     AGTGPAYHKLSYLGRVVREIVETERMYVQDLRSIVEDYLLKIIDTPGLLKPEQVSALF
                     GNIESIYALNSQLLRDLDSCNSDPVAVASCFVERSQEFDIYTQYCNNYPNSVAALTEC
                     MQDKQQAKFFRDRQELLQHSLPLGSYLLKPVQRILKYHLLLQEIAKHFDEEEDGFEVV
                     EDAIDTMTCVAWYINDMKRRHEHAVRLQEIQSLLINWKGPDLTTYGELVLEATFRVHR
                     VRNERTFFLFDKILLITKKRGDHFVYKGHIPCSSLMLIESTRDSLCFTVTHYKHSKQQ
                     YSIQAKTVEEKRSWTHHIKRLILENHHATIPQKAKEAILEMDSYYPSRYRCSPERMKK
                     AWSSQDEVSAHVRQGRRQSEPGRTLFSRATLPSRQQGFEMPGLKGRRKSEPTRHLLRQ
                     LSEKVARAAGMKHAGSAGALLDFGQLPHAQDQQPEAEEAAREELEEEEEIVEEEEQQQ
                     QQTFPVSLEDLAGHGGNEKVPGPELPGSEEEEEEEESLAVAEQVADFASSLLAALHCW
                     HYRANALLFSRGAMGKRHGESEGSKSCRRPSDRSPTSVEKRMSFESVSSMPEESSEQV
                     ETDPEPRAEQEAFTALEGPSPEEMPSDPEFPEALETQLHDPKGLLGVDKPAGEVDFVE
                     PEGSEDLKTLSSEEEEEEEMGATQEPESLLPPSVLDQASVIAERFASSFSRRSSLAAE
                     DGKCSGLGTPRLISRSSSVLSLEGSEKGLARWSSTGDSLSNPPAPEVIIGTDTVTDTG
                     PSVNGTESLSAGSGCPTELDRSSCKKKESALSTRDRQLLDRIKSYYENAEHHDASFSI
                     RRRESLSYIPKGLVRNSVSRFNSLPKPDSEPAAPVGYKRPGSSRPASWTLFDLPGPSR
                     ADEGDPAPITDAEFRPSSEIAKIWERMESSERSPRTGSGQSQANGFELQEPLFILEEH
                     ELGAITEESAVASPESASPTEHPSPAHLARELKELVKELSSGVQGELVTPLHPRIMQL
                     SHVMDSHVSERVKNKVYQLARQYSLRIKNIKAARPPLHWEKATPDGDEPIPSNSGLPV
                     EAGELSGGKARRKPVLSLLSYEQLVAQEPGTSKSSSAVETSPRRFSFSPSAVSPRTTS
                     PGSRSSARSPLSPFDTETFNWPDVRELCSKYTSHDKTAQAESSWPRSLLVNRSRSLPE
                     NIIEPPVSGKADYCCSLNTNGRQGDGEASQPPPPESPPQSQLNGGEALYVTADLTLEN
                     NRRVIIMEKGSHPSSTMGLEEDSGKEPSSSVVLKGQGQGFQESAEHQPKEDSPRDSAD
                     TNKQGRVRNLREKFQALNSVG"
ORIGIN      
        1 atgactctgt ttgggcctct ttctgaggtt atcaccctgt gtgggaactt tttcccagga
       61 aaaatgttaa cttttaaaaa ggaggtatcc catgagggag tgtggattcc tctcaggctc
      121 catcgagtct cctgggtcct gtgtgtgagg agggggaggt gtgtgttgct tgtgaatgaa
      181 ttgctcaggg atcctggatt ccagcaaacc ctgtcttccc acttccctag ctgcgtggcc
      241 ttgagtgggg gagtattgag aaactacata gcgaatgtgt cagatgtgtc agagctgtgg
      301 ctggtacatt acaccctcgt aaaaggttgc ctgagatttt agtttgctct ctgggaacag
      361 cttgtgcctc agttttcctg accagaaaag caggggtaat tttgctgtcc acctgtccca
      421 ccctctgact tgcagccttg aggacggaag ggttaaaagc ctcaggctta gagggcccga
      481 gtgggggaag gtgtcccata aatggagtat tgttgtgctg ttgactgatc tggctttgtt
      541 tgagtcttca gggtttgacc tcctgcactt cggaccccaa gtgcttaatc tctggagata
      601 tttgtggtcc tcagctgcaa ggtgcttacc tcctggggct gtggcctggg tcctcatccc
      661 ttctggggcg tgctacgttg tgctgggaag ctacattttc atggttaggc cccccagcaa
      721 tcaggaatga gagaaatgca gcaagtatga cccacacgcg gaactggttc tgaataggac
      781 gtttattgaa gaggtttcag caggaggcag cgggcgcttt aattcccgag gttgttggtg
      841 gcagttgttg cttgcccagc cagagcttgt taaccgctgg gctgccaaac gccggagaga
      901 atgcagctcc ccagcccctg gccaccttcc cagggctgct ctctgtgctg ggatgggagc
      961 ccttttgagg aaagcgaatc tccccgaggt gacagtccca ggcagcgatg ccaggatgcc
     1021 cgtctctact gccctccacc aagatggcag ccaggagcgg ccaccgagcc taatgtctac
     1081 tacatcttca tctggctcct cccgtgacag ccacagtgcc atggaggagc cgactggctc
     1141 cgaggcttca gcccagaacg ggacaggctc cccttggggc cggcatattc ccaacagcaa
     1201 caacaactcc agcagctggc tgaacatgaa gggacctctc tccccattca acggccgtgc
     1261 agggacaggc cctgcctatc acaagctcag ctatctgggc cgggtggtgc gagagatcgt
     1321 ggagacagag cgcatgtatg tgcaggacct gcggagcatt gtggaggact acctcttgaa
     1381 gatcatcgac acccccgggc tcctgaagcc ggagcaagtc agcgccctct ttgggaacat
     1441 agagagcata tatgcactga acagccagct tctcagagac ctggacagct gcaatagtga
     1501 ccccgtggca gttgccagct gcttcgtgga aaggagccaa gagtttgata tatacactca
     1561 gtattgcaac aactacccca actcagtggc agccctcacg gagtgcatgc aagacaagca
     1621 gcaagccaag ttcttccggg accggcagga gctgttgcag cactccctgc ccctgggctc
     1681 ctacctgctg aagccagtcc aacgcatcct caagtaccac ctgctgctcc aggaaattgc
     1741 caaacatttt gatgaagaag aggatggctt cgaggtggta gaagacgcca ttgacaccat
     1801 gacgtgtgtg gcctggtaca tcaatgacat gaagaggagg cacgagcacg cagttcggct
     1861 acaggagatc cagtcactgc tcattaactg gaagggacca gacctgacca cctacgggga
     1921 actggtcctg gaagccacct ttcgcgtgca ccgtgtgcgc aatgagagaa ctttcttcct
     1981 ctttgacaag atactgctca ttaccaagaa gcgaggcgat cactttgtct acaagggcca
     2041 cattccgtgc tcctcactga tgctgatcga aagcaccagg gactctctgt gcttcaccgt
     2101 cacccactat aagcacagca aacaacaata cagtatccag gccaagacag tagaggagaa
     2161 acggagctgg actcaccaca tcaagaggct catcctggag aatcaccatg ctactatacc
     2221 ccagaaggcc aaggaagcca tcttggaaat ggactcctat tatcccagta ggtatcgctg
     2281 cagcccggag cggatgaaaa aggcttggtc ctcgcaggat gaggtgtctg cccatgtgcg
     2341 ccagggacgt cggcagtctg agcctggccg taccctgttc agcagggcaa cacttcccag
     2401 caggcagcaa ggattcgaga tgccaggcct taagggccgt agaaagtcgg agcccaccag
     2461 gcacctgctc aggcagctga gtgagaaagt agccagagca gcgggaatga agcacgcagg
     2521 gagtgccgga gccctcttgg actttgggca gctaccccat gcacaggacc agcagccaga
     2581 ggctgaggag gctgccaggg aggagcttga ggaagaggag gagatagtgg aggaggaaga
     2641 gcagcagcag cagcagacct ttccagtctc cctggaggac ctggcagggc acggtggcaa
     2701 cgagaaggtg cctgggccag agctcccggg ctcggaggag gaggaagagg aggaagagag
     2761 cctagcagtg gcggagcagg tagctgactt tgccagctcc ctgctggccg ccctccactg
     2821 ctggcactat cgagccaacg ctttactttt ctcccggggt gctatgggga agagacatgg
     2881 ggagtctgaa ggctctaaaa gctgcagaag gcccagtgac cggtctccaa ccagtgtgga
     2941 gaaacgcatg agctttgagt ctgtttcttc tatgccagag gagagcagtg agcaggttga
     3001 gacagatcct gagcccaggg ctgagcagga ggcctttact gccttggaag gtcctagccc
     3061 tgaggagatg ccttcagacc cagaatttcc agaagccctg gagacacagc ttcatgaccc
     3121 caaggggctg ctaggagtgg acaagcccgc tggtgaggtg gactttgtgg agcctgaggg
     3181 gtctgaagac cttaagaccc tgagtagtga ggaggaagaa gaggaggaaa tgggagccac
     3241 ccaggaaccc gagagcctcc tgccaccctc tgtgctggac caggccagcg tcattgccga
     3301 gaggttcgcc agtagcttct ctcggcggag cagcctggca gcggaggacg gcaagtgcag
     3361 tggcctcggg acaccacggc tcatcagcag gagcagcagc gtgctcagcc tggagggcag
     3421 cgagaagggc ctggcccgat ggagcagcac tggagactcc ctcagcaacc cgcccgcccc
     3481 agaagtgatc atcggtacag atacagtcac ggacactggc ccttctgtca atgggacaga
     3541 atctctaagt gcaggctcag gctgccccac ggaactggat agatcatcct gcaagaaaaa
     3601 ggaatcagca ttgtctaccc gagaccgaca gttgctggac agaattaaga gctactatga
     3661 aaacgcagag caccacgatg ccagtttcag catccgtcgg cgggagagcc tctcctacat
     3721 ccctaaagga ctggtgcgca actctgtgtc caggttcaac agccttccca agccagattc
     3781 agagccagca gctcccgttg ggtacaagag gccggggagt tctcggccag cctcatggac
     3841 cttgtttgac ctcccaggtc ccagccgggc agacgaaggg gacccagctc ctatcacaga
     3901 tgcggagttc cgtccatctt cagaaattgc caagatatgg gaaagaatgg agtcttcgga
     3961 gagaagtccc cggacagggt ctggccagag ccaggccaat ggctttgagc tacaagagcc
     4021 actgttcatc ttggaggagc atgagctggg ggccatcact gaggagtctg ctgtcgcctc
     4081 tccagaaagt gcctctccca ctgagcatcc cagcccagcc cacctggccc gggagctgaa
     4141 agagctggtg aaggagctga gcagtggtgt ccagggggag ctggttaccc cactgcaccc
     4201 ccgtattatg cagctgtccc atgtgatgga cagccatgtg agtgagcgtg tcaaaaacaa
     4261 ggtctaccag ttggcccgcc agtatagcct ccgaattaag aacatcaagg cagctaggcc
     4321 acctctacac tgggaaaaag ccactcctga tggggatgag cccatccctt ccaattctgg
     4381 cctgcctgtg gaagctggag agctgtcagg gggcaaagcc aggaggaagc ctgtgctatc
     4441 cctcctcagc tatgagcagc tggtggctca ggagcctggc acctccaagt cttcctctgc
     4501 tgtggagacc tctccacgcc gtttctcctt cagcccttct gctgtcagcc caagaaccac
     4561 ctcacctggg tctcggtcct ccgctcggag ccccctcagc ccctttgaca ctgagacctt
     4621 caactggccc gatgtccgag agctctgctc caagtatacc tcccacgaca agactgctca
     4681 ggccgagagc agctggcccc gtagcctgct ggtcaacagg agccgctcct tgcctgagaa
     4741 cattatagaa cctcctgtgt ctggcaaggc ggactactgc tgcagcctga acaccaatgg
     4801 gcgccaggga gatggggagg ccagccagcc tccacctcct gagtctcctc cccaaagcca
     4861 gctgaacgga ggtgaagccc tgtatgtcac cgcagacctt accctagaga acaaccggcg
     4921 agtgatcatc atggagaagg ggtcccatcc tagctctacc atgggactgg aggaagacag
     4981 tgggaaggaa ccaagttcct cagtggtttt gaagggacag ggccaaggtt tccaggagtc
     5041 tgcagagcac cagcccaaag aagacagtcc tagggactca gcggacacaa acaaacaggg
     5101 tagagtgaga aacctgaggg agaagtttca ggccttgaac tctgtgggtt gactgactcc
     5161 tgaaggagag aacagccgtg tggcggtgga aaggacctgc cgtgctttcc cccaggcctg
     5221 gcacaccagg ctgttctcca ttcttctgga agagtggttt gagaaacgtg tgaactcacc
     5281 tgctacccat gctggcacct cccttccctg gggaggtccc atgatgatga ctttccttag
     5341 gtccagatga gccacttatc ttttctgtaa atacttccct gataagaagc caacgatttt
     5401 atttaaactt cttctgccca gggagagcaa gcactgtcct ggcttccctt actggctggc
     5461 cactgcccag ctgagaacca aggcgagacc taggaagcag tctgggcagg ctttgccctt
     5521 taactgcctt gtcataggac ccaggcagga atgaggccaa taatttattg ctttccatcc
     5581 tgtggtgtgt gtgtgtgagt gagtgtgtgt gtgtcttgta aagactgtaa cggacctaat
     5641 tcaggtactc tggcaggctg tcttgctggc cctgtggttc ttgctaatgt atacacattt
     5701 cattatttac ctatggtgca ataagcactg tgaccaacca a
//
