LOCUS       NM_172033               1901 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus pleckstrin homology domain containing B1
            (Plekhb1), mRNA.
ACCESSION   NM_172033
VERSION     NM_172033.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1901)
  AUTHORS   Etournay,R., El-Amraoui,A., Bahloul,A., Blanchard,S., Roux,I.,
            Pezeron,G., Michalski,N., Daviet,L., Hardelin,J.P., Legrain,P. and
            Petit,C.
  TITLE     PHR1, an integral membrane protein of the inner ear sensory cells,
            directly interacts with myosin 1c and myosin VIIa
  JOURNAL   J Cell Sci 118 (Pt 13), 2891-2899 (2005)
   PUBMED   15976448
REFERENCE   2  (bases 1 to 1901)
  AUTHORS   Andrews,K.L., Potdar,P.D., Nettesheim,P. and Ostrowski,L.E.
  TITLE     KPL1, which encodes a novel PH domain-containing protein, is
            induced during ciliated cell differentiation of rat tracheal
            epithelial cells
  JOURNAL   Exp Lung Res 26 (4), 257-271 (2000)
   PUBMED   10923244
REFERENCE   3  (bases 1 to 1901)
  AUTHORS   Xu,S., Ladak,R., Swanson,D.A., Soltyk,A., Sun,H., Ploder,L.,
            Vidgen,D., Duncan,A.M., Garami,E., Valle,D. and McInnes,R.R.
  TITLE     PHR1 encodes an abundant, pleckstrin homology domain-containing
            integral membrane protein in the photoreceptor outer segments
  JOURNAL   J Biol Chem 274 (50), 35676-35685 (1999)
   PUBMED   10585447
REFERENCE   4  (bases 1 to 1901)
  AUTHORS   Krappa,R., Nguyen,A., Burrola,P., Deretic,D. and Lemke,G.
  TITLE     Evectins: vesicular proteins that carry a pleckstrin homology
            domain and localize to post-Golgi membranes
  JOURNAL   Proc Natl Acad Sci U S A 96 (8), 4633-4638 (1999)
   PUBMED   10200314
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF081582.1.
            
            On Feb 21, 2013 this sequence version replaced NM_172033.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF081582.1, AF118562.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMEA5760396
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1901              AF081582.1         1-1901
FEATURES             Location/Qualifiers
     source          1..1901
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q32"
     gene            1..1901
                     /gene="Plekhb1"
                     /gene_synonym="Evt1; Kpl1"
                     /note="pleckstrin homology domain containing B1"
                     /db_xref="GeneID:64471"
                     /db_xref="RGD:621614"
     exon            1..143
                     /gene="Plekhb1"
                     /gene_synonym="Evt1; Kpl1"
                     /inference="alignment:Splign:2.1.0"
     exon            144..219
                     /gene="Plekhb1"
                     /gene_synonym="Evt1; Kpl1"
                     /inference="alignment:Splign:2.1.0"
     CDS             183..854
                     /gene="Plekhb1"
                     /gene_synonym="Evt1; Kpl1"
                     /note="PH domain-containing family B member 1; evectin-1;
                     pleckstrin homology domain containing, family B (evectins)
                     member 1"
                     /codon_start=1
                     /product="pleckstrin homology domain-containing family B
                     member 1"
                     /protein_id="NP_742030.1"
                     /db_xref="GeneID:64471"
                     /db_xref="RGD:621614"
                     /translation="MALVRGGWLWRQSSILRRWKRNWFALWLDGTLGYYHDETAQDEE
                     DRVVIHFNVRDIKVGQECQDVQPPEGRSRDGLLTVNLREGSRLHLCAETRDDAIAWKT
                     ALMEANSTPAPAGATVPPRSRRVCPKVRCTSLSWKPCKVERRIWVRVYSPYQDYYEVV
                     PPNAHEATYVRSYYGPPYGPGVTHVIVREDPCYSSGAPLAMGMLAGAATGAALGSLMW
                     SPCWF"
     exon            220..372
                     /gene="Plekhb1"
                     /gene_synonym="Evt1; Kpl1"
                     /inference="alignment:Splign:2.1.0"
     exon            373..475
                     /gene="Plekhb1"
                     /gene_synonym="Evt1; Kpl1"
                     /inference="alignment:Splign:2.1.0"
     exon            476..515
                     /gene="Plekhb1"
                     /gene_synonym="Evt1; Kpl1"
                     /inference="alignment:Splign:2.1.0"
     exon            516..620
                     /gene="Plekhb1"
                     /gene_synonym="Evt1; Kpl1"
                     /inference="alignment:Splign:2.1.0"
     exon            621..717
                     /gene="Plekhb1"
                     /gene_synonym="Evt1; Kpl1"
                     /inference="alignment:Splign:2.1.0"
     exon            718..1901
                     /gene="Plekhb1"
                     /gene_synonym="Evt1; Kpl1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aggcagtgcg ctgagcctgg ggagtgaaat gcctcaggct ctctgggggt atgcaaagcg
       61 caggtgcgac cagctcgggt agcatcttca tcgagtagca gcggggcatt tgtggcagcg
      121 gtatccacaa caggtgtgaa caggtcccac ccgactccac cctggaaagt ccttttgaag
      181 aaatggccct ggtgaggggc ggctggctat ggagacagag ctccatcctc cgccgctgga
      241 agcggaattg gtttgctctg tggttggatg gcacgctggg ttactaccac gatgagacgg
      301 cacaggacga ggaggaccgt gtagttatcc acttcaatgt ccgagacata aaggtcggcc
      361 aggagtgtca ggatgtgcag cccccagagg gcaggagccg agatggcctg ctgacagtga
      421 acctacggga gggttcccgc ctgcacctgt gcgcagagac ccgggatgat gccatagcat
      481 ggaagacagc cctgatggag gcaaactcca ccccggcccc agctggagcc accgtcccac
      541 ccaggagccg tcgggtttgc cctaaggtca ggtgtacgag cctctcatgg aagccctgta
      601 aggttgagag gcggatctgg gtacgcgtct acagtccata tcaagactac tatgaggtgg
      661 taccccccaa cgcacacgag gccacgtatg tccgcagcta ctatgggcca ccttatggtc
      721 ctggtgtgac acatgtgatc gtgcgagagg atccctgcta cagctctggc gcccctttgg
      781 ccatgggcat gcttgctggg gctgccacgg gtgctgccct tggctcactt atgtggtcgc
      841 cttgctggtt ctgagccctg gggctccaac ctctggatgt gcacgtagaa cgcaaaaccc
      901 ttttcttctg gaccctctcc tatctaccac ctaaactctg tcccattttg acccctttct
      961 ctccattaag tcctctaggc ttggcccatt cttcccacca tttatcctcc acttatcctc
     1021 cttccctctc agagaaagct aacatctcag acacagacac agcggaacgt ccatacacct
     1081 actgccaggc aacctcataa atcacatggg aatttcctct agacacagca aacataactt
     1141 catttggctt taagtgtctg aggaatggaa ctcacaagag agcaaacaac aaagttacag
     1201 ttacctgtct ggcaaggata agtgggggca agggcaaggc agacagttta ggtgcctaaa
     1261 ggatcacatg acagttggct tggcgttgtg gcaggggttg tagtggcctt agctttaggc
     1321 gaaggagctt gctggataaa ggcatgatgg ggctttttat gaagtttctg gatttcaact
     1381 ataatgaata ctttgcttgt ctagttagta ctggcagaac atacaccctt atccagaaca
     1441 cggcatttgg caccttttcc ccacttggta gcttccctat gatagttcag ctaaccctaa
     1501 ggtttcctag ctgtggaaca ggtgagctct ttgggacctc tggccttaca aagttgcttc
     1561 cattaggaaa tgcctttctg atcccaggag ctcagctctg actttgactg ttaacatctg
     1621 aagctttttc tcttccttca ctctggaggg aaatggaatt attttgctct agggcctgac
     1681 ccaccttggc accagcttgg ggaatctctc atgtgcctgt ctgtaggtgg caagcaatct
     1741 ttccatttga tcccattcca aactattcca tcagtctgtc ccaattgcca atagaaaagc
     1801 taaaatccct ggctcagagg ccagagtgcc cactaaaatt cctagcatat gtgagggcac
     1861 cactggctca gctgcagaca ctaataaaga tatgactggc c
//
