LOCUS       XM_008764396            5295 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus phospholipase C, eta 2 (Plch2),
            transcript variant X1, mRNA.
ACCESSION   XM_008764396
VERSION     XM_008764396.3
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051340.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_008764396.4.
            
            On Jan 21, 2021 this sequence version replaced XM_008764396.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5295
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..5295
                     /gene="Plch2"
                     /note="phospholipase C, eta 2; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 4
                     ESTs, 1 Protein, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 4 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:313756"
                     /db_xref="RGD:1304675"
     CDS             86..4798
                     /gene="Plch2"
                     /codon_start=1
                     /product="1-phosphatidylinositol 4,5-bisphosphate
                     phosphodiesterase eta-2 isoform X1"
                     /protein_id="XP_008762618.2"
                     /db_xref="GeneID:313756"
                     /db_xref="RGD:1304675"
                     /translation="MTSLSALLWLRGAASRCGKRSQPRPLLVQGSGHAEARGEAAGAS
                     LQKEYFGCGGARGGCWPRCPPGSQSLRVALARGSTSRPALRAALPGPPAPSQRGAGRG
                     CGAGGTSDSALLARRLHGAQCHSAERAARTVRRGSPALAKRCPRSLSLSQSQATDHPS
                     PRPRGHLAAVNAETMDAGAAPQKHMERCMSAMQEGTQMVKLRGSSKGLVRFYYLDEHR
                     SCLRWRPSRKNEKAKISIDSIQEVSEGRQSEIFQRYPDSSFDPNCCFSIYYGSHRESL
                     DLVSPSSEEARTWVTGLRYLMAGISDEDSLARRQRTRDQWLKQTFDEADKNGDGSLSI
                     SEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMMSTRRDLYLLML
                     TYSNHKDHLDASDLQRFLEVEQKMSGVTLESCQSIIEQFEPCLENKSKGVLGIDGFTN
                     YTRSPAGDIFNPEHHRVHQDMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVLQA
                     GCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHC
                     SVVQQKKMAQYLTDILGDKLDLSSVSGEDATMLPSPQMLKGKILVKGKKLPANISEDA
                     EEGEVSDEDSADEIEDDCKLLNGDASTNRKRVENIAKKKLDSLIKESKIRDCEDPNDF
                     TVSTLSPSGKLGHKAEAKKAQSKAEEDVESGEDTGVSRRNSRLLMSSFSKRKKKGSKI
                     KKVASVEEGDESLDSPGSQSRGTARQKKTMKLSRALSDLVKYTKSVGTHDVEMEVVSS
                     WQVSSFSETKAHQILQQKPAQYLRFNQHQLSRIYPSSYRVDSSNYNPQPFWNAGCQMV
                     ALNYQSEGRMLQLNRAKFSANGGCGYVLKPQCMCQGVFNPNSEDPLPGQLKKQLALRI
                     ISGQQLPKPRDSVLGDRGEIIDPFVEVEVIGLPVDCSKEQTRVVDDNGFNPMWEETLV
                     FTVHMPEIALVRFLVWDHDPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVA
                     VSDISGKVKQTLGLKGLFLRGPKPGSLDSHAAGQPLPRPSVSQRLLRRTASAPTKSQK
                     PSRKGFPELALGTQDAGSEGAADDVAPPSPNPALEAPTQERSGSSSPRDTRLFPLQRP
                     ISPLCSLEPIAEEPALGPGLPLQAAVPTGPSQEGPQCPVGQGAKVTGPQQTSLGASGT
                     LQLRTGGDREKEEPPLRPHNGGIPHGPREGTSGRQTDSKSRSWAPGHLPVVRRAKSEG
                     QVLSELSPTPAVYSDATGSDRLWQRLEPGSHRDSVSSSSSMSSNDTVIDLSLPSLGLC
                     RSRESIPGVSLGRLTPRPCLASAARPDLPPVTKSKSNPNLRVAGGLPLAPDELQPRPL
                     APRLTGLHSRPPWHHLTLVGLRDCPVSAKSKSLGDLTADDFGPSFQGSTGSLSCGLSP
                     LGVVHQVLEPGRRRDALTEQLRWLTGFQHAGDITSPTSLGPAADGSVGGPSFLRRSSS
                     RSQSRVRAIASRARQAQERQQRLRGLDSRGPPEEERGTPEGACSVGHEGCVDVPMPAK
                     GAPEQVCGAADDQLLLRL"
ORIGIN      
        1 gcgctctgca tgtgctgcct gacctctggg ttctggggag atgtgaccca gaccctcctc
       61 ttcaagcacc tgcgggcgga gagcaatgac ctccctctca gctctgcttt ggctgcgtgg
      121 agcagcctcg agatgtggga agcgctctca gccccgcccc ctcctggtcc aaggctccgg
      181 ccacgcagag gcgagggggg aggctgcggg tgcttctttg cagaaagagt actttggttg
      241 cggcggggcg cggggcgggt gctggccccg ctgtcctcct ggctcccagt ctctgcgcgt
      301 tgcgcttgcc cgcggttcca cgtcgcgtcc cgctctacgc gcagcgctgc cgggcccccc
      361 ggccccctcc cagcgcgggg cgggcagggg gtgtggtgcg ggcggcacga gtgacagcgc
      421 gctcctcgcg cggcgcctcc acggggctca gtgtcacagc gccgaacgcg ctgcgcgcac
      481 agtccgccgc gggtcgccag ccctggcaaa gcgatgtcct cggagcctta gcctcagtca
      541 gagccaggcc actgaccacc cgagtcctcg ccctcgtggc cacctcgctg ctgtcaacgc
      601 ggagacaatg gacgcgggag ccgccccgca gaagcacatg gaacgatgca tgagtgccat
      661 gcaggagggg acccagatgg tgaagctccg tggcagctcc aagggcttgg tccgcttcta
      721 ctacctggat gagcaccgtt cctgcctccg ctggcggccc tcacgcaaga acgagaaagc
      781 caagatttcc atcgactcca tccaggaggt gagtgagggc cggcagtctg aaatcttcca
      841 gcgctacccg gacagcagct ttgaccccaa ctgttgcttc agcatctact acggcagcca
      901 ccgagagtcg ctggacttgg tctcaccaag cagtgaagag gcacgtacct gggtcaccgg
      961 ccttcgctac ctcatggctg gcatcagcga cgaagacagc ctagcccgtc gccagcgtac
     1021 cagggaccag tggctgaagc agacgtttga tgaggctgac aagaacggtg acggtagcct
     1081 gagcatcagc gaggtcctgc agctgctaca taaactcaac gtgaacctgc cccggcagag
     1141 ggtgaaacag atgttcaggg aggcagacac agatgaccat caggggacac taggctttga
     1201 ggaattctgc gccttctaca agatgatgtc cactcgccga gacctctacc tgctcatgct
     1261 gacctacagc aaccataagg accacttgga tgcctccgac ctgcagcgct ttctggaggt
     1321 ggagcagaag atgagcggcg tgacgctcga gagctgtcag agcatcatcg agcaatttga
     1381 gccttgtctg gagaataaga gcaaaggggt gttggggatt gatggcttta ccaactacac
     1441 gcggagcccc gccggtgaca tcttcaaccc tgagcaccac agagtgcacc aagacatgac
     1501 gcagcctctg agtcactact tcatcacctc ctcccacaac acctacctcg tgggtgacca
     1561 gctcatgtcc cagtctcggg tggacatgta tgcctgggtc ctgcaggccg gctgccgctg
     1621 tgtggaggtg gactgctggg atgggcctga tggggaaccc attgtccacc atggctacac
     1681 tctgacctcc aagatccttt tcaaagatgt catcgaaacc atcaacaaat atgccttcat
     1741 caagaatgag tacccagtga tcctgtccat tgagaaccac tgtagtgttg ttcagcagaa
     1801 aaagatggcc cagtatctca ctgacatcct tggagacaag ctggacctct cctcagtgag
     1861 cggcgaagat gccaccatgc ttccttctcc acagatgctc aagggcaaga tcctggtgaa
     1921 ggggaagaag ctccctgcca atatcagtga ggatgcagaa gaaggtgaag tgtctgatga
     1981 ggacagtgcc gatgagattg aggatgattg caagctcctc aacggagacg cctccaccaa
     2041 tcggaagcgt gtggaaaaca tcgctaagaa gaagttggat tctctgatca aggagtcaaa
     2101 gatccgtgac tgtgaagacc ccaatgactt cactgtctcc acactgtccc catctgggaa
     2161 gcttgggcac aaagcagagg ccaagaaggc tcagagcaag gccgaggaag atgtggagtc
     2221 tggggaggac accggggtga gcaggcggaa cagccgtctc ctcatgagca gcttctccaa
     2281 gcgtaagaaa aaaggcagca agataaagaa ggtggccagc gtggaggagg gggatgagag
     2341 cctggactcc ccaggaagcc agagccgtgg gactgcccgg caaaagaaga ccatgaagct
     2401 gtcacgagcc ctctcggacc tagtgaaata taccaagtct gtgggaaccc atgacgtgga
     2461 aatggaggtg gtatctagct ggcaagtgtc gtccttcagc gagaccaagg cccaccagat
     2521 cctgcagcag aagcctgccc agtacctgcg ctttaaccag caccagctct cccgcatata
     2581 cccctcctcc taccgggtgg actccagcaa ctacaatcca caacccttct ggaatgctgg
     2641 ttgccagatg gttgccctga actaccagtc ggaggggcgg atgctgcagc tgaacagggc
     2701 aaagttcagt gccaacggtg gctgtggcta cgtgctcaaa ccccaatgca tgtgccaggg
     2761 tgttttcaac cccaactctg aggacccctt gccagggcag ctcaagaagc agctggccct
     2821 gaggatcatt agtggccagc agctgcccaa gcctcgggac tcggtgctgg gtgaccgtgg
     2881 ggagatcatc gaccccttcg tggaggtgga ggtcatcggg ctccccgtgg actgcagcaa
     2941 ggagcagacc agagtggtgg atgacaatgg gttcaacccc atgtgggagg agacactggt
     3001 gttcactgta cacatgcccg agattgcgct tgtgcgcttc ctggtctggg accacgaccc
     3061 gattggacgg gacttcatcg gccagaggac gctggccttt agcagcatga tgccaggcta
     3121 ccggcacgtg tacctagaag gcatggagga ggcctccatc tttgtacatg tggccgtcag
     3181 tgacatcagt ggtaaggtca agcagactct gggtctaaaa ggtctcttcc tccgaggccc
     3241 aaagccaggc tcactggaca gtcatgctgc tgggcagccc ctgccccggc cctccgttag
     3301 ccagaggctc ctgcggcgca cagccagtgc cccaaccaag agccagaagc caagtcgcaa
     3361 gggcttccca gagctggccc tgggcacaca ggacgcaggc tccgaggggg cggctgacga
     3421 cgtggcaccc cctagcccca acccagctct ggaggcccct actcaagaga ggtcaggcag
     3481 cagcagtccc cgagacactc gcctcttccc cctgcagcgg cccatctccc ccctgtgcag
     3541 cctggaaccc attgctgagg aaccagccct gggccctggc ctcccgttac aggcagctgt
     3601 ccccacaggt ccatctcagg aagggcccca gtgccctgta ggacagggag ccaaagtgac
     3661 cggcccccag cagacgtctc tgggagcttc tggaaccctc cagctcagga ctgggggcga
     3721 tagggaaaag gaagagccac ctctcaggcc acacaacggt gggattcccc acgggccacg
     3781 tgaggggaca tctggaagac agacagacag caagagccgc tcctgggccc cgggccactt
     3841 gccagtggtt aggagggcca agagtgaggg ccaggtgctc tcggagctct ctcccacacc
     3901 tgcagtatac tcggatgcta caggctctga caggttatgg cagcggctgg agcctgggag
     3961 tcacagggac agtgtctcct catcctccag catgtcctcc aatgacactg tcatagacct
     4021 ctcattgccc agcctcggcc tctgccgcag tcgagagagc attccagggg tctctcttgg
     4081 acgcctaacc ccacggccct gcttagcctc agctgcccgt cctgacctgc ctcctgtgac
     4141 caagagcaaa tccaacccca acctgcgggt tgcgggtggg ttgcctcttg cacccgatga
     4201 gctgcagccc cggcctcttg ccccacggct gactgggctc cactcacggc caccctggca
     4261 tcacctcacc ctggtgggcc tgagggactg cccagtgtct gctaagtcca agagtctggg
     4321 agacctgacg gctgacgact ttggtcccag ctttcagggc agcacgggca gcctgagctg
     4381 cggcctgagc cccctgggtg tggtgcatca ggtgctggag ccggggagga ggcgagatgc
     4441 tctcacagag cagctacgct ggctcaccgg cttccagcat gcgggggaca tcacatcacc
     4501 caccagcttg ggcccagctg cggatggctc tgtagggggt cccagcttcc tgagacgttc
     4561 ctcctcgcgc agccagagcc gagtgcgtgc tattgccagc cgagcccgcc aagctcagga
     4621 gcgccagcag aggctgagag gcctggactc acggggtccc ccagaggagg agcggggcac
     4681 ccctgagggt gcctgttctg taggccacga gggctgtgtg gatgtgccaa tgcctgccaa
     4741 gggagcccct gagcaggtgt gtggtgctgc tgatgaccaa ctgctgctca ggctctgact
     4801 ctgcctgatg actccaactc cctaccttcc ctgtgactgc tggccggggt gggtgggggt
     4861 ggggctggcc tcaacccgac ctttgctcag gaaatgaagc cactgggtcc ccgaagctgt
     4921 tatgccccac tcgccgcctc tggagcaccc agtagccccc tcttcaacct ttggctgtcc
     4981 tcttgtctct gatcctggga agtgaggaac agcactgtcc acctgtccta ctgggcagtt
     5041 tccacatttt aagatattta actttttaga accaaaaact tacaaatgac tctgcgtcct
     5101 ttcccactgg tctgcctggt gtgtgctgag tgttatcttc caccagctgt gtgcttgtat
     5161 cccaggatgc ctgtgacaca cccacaactg ctaggatgtt tgtccctgca ccctactcca
     5221 ctgtgcacaa actgcccagc aattgtgtaa acttgggaac acaactccaa taaatgcatc
     5281 aggcctgttc tgtgc
//
