LOCUS       NM_001191707            5623 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus phospholipase C, eta 1 (Plch1), mRNA.
ACCESSION   NM_001191707 XM_227208
VERSION     NM_001191707.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5623)
  AUTHORS   Hwang,J.I., Oh,Y.S., Shin,K.J., Kim,H., Ryu,S.H. and Suh,P.G.
  TITLE     Molecular cloning and characterization of a novel phospholipase C,
            PLC-eta
  JOURNAL   Biochem J 389 (Pt 1), 181-186 (2005)
   PUBMED   15702972
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Jul 17, 2010 this sequence version replaced XM_227208.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA5760383, SAMEA5760389
                              [ECO:0000350]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-136               JAXUCZ010000002.1  150387663-150387798 c
            137-380             JAXUCZ010000002.1  150385217-150385460 c
            381-510             JAXUCZ010000002.1  150378235-150378364 c
            511-681             JAXUCZ010000002.1  150374638-150374808 c
            682-775             JAXUCZ010000002.1  150357194-150357287 c
            776-979             JAXUCZ010000002.1  150355096-150355299 c
            980-1100            JAXUCZ010000002.1  150347067-150347187 c
            1101-1272           JAXUCZ010000002.1  150342715-150342886 c
            1273-1380           JAXUCZ010000002.1  150334939-150335046 c
            1381-1542           JAXUCZ010000002.1  150325731-150325892 c
            1543-1614           JAXUCZ010000002.1  150324133-150324204 c
            1615-1706           JAXUCZ010000002.1  150322061-150322152 c
            1707-1804           JAXUCZ010000002.1  150318075-150318172 c
            1805-1984           JAXUCZ010000002.1  150313982-150314161 c
            1985-2092           JAXUCZ010000002.1  150313778-150313885 c
            2093-2217           JAXUCZ010000002.1  150312353-150312477 c
            2218-2302           JAXUCZ010000002.1  150310469-150310553 c
            2303-2449           JAXUCZ010000002.1  150306851-150306997 c
            2450-2529           JAXUCZ010000002.1  150306433-150306512 c
            2530-2884           JAXUCZ010000002.1  150304054-150304408 c
            2885-5623           JAXUCZ010000002.1  150299075-150301813 c
FEATURES             Location/Qualifiers
     source          1..5623
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q31"
     gene            1..5623
                     /gene="Plch1"
                     /gene_synonym="Plcl3; RGD1561991"
                     /note="phospholipase C, eta 1"
                     /db_xref="GeneID:310463"
                     /db_xref="RGD:1561991"
     CDS             1..4959
                     /gene="Plch1"
                     /gene_synonym="Plcl3; RGD1561991"
                     /EC_number="3.1.4.11"
                     /note="phospholipase C-like 3"
                     /codon_start=1
                     /product="1-phosphatidylinositol 4,5-bisphosphate
                     phosphodiesterase eta-1"
                     /protein_id="NP_001178636.1"
                     /db_xref="GeneID:310463"
                     /db_xref="RGD:1561991"
                     /translation="MSVMQSGTQMIKLKRGTKGLVRLFYLDEHRTRLRWRPSRKSEKA
                     KILIDSIYKVTEGRQSEIFHRQAEGNFDPSCCFTIYHGNHMESLDLITSNPEEARTWI
                     TGLKYLMAGISDEDSLAKRQRTHDQWVKQTFEEADKNGDGLLNIEEIHQLMHKLNVNL
                     PRRKVRQMFQEADTDENQGTLTFEEFCVFYKMMSLRRDLYLLLLSYSDKKDHLTVEEL
                     AQFLKVEQKMSNVTLDYCLDVIKKFEVSEENKVKNVLGIEGFTNFMRSPACDVFNPLH
                     HEVYQDMDQPLCNYYIASSHNTYLTGDQLLSQSKVDMYARVLQEGCRCVEVDCWDGPD
                     GEPVVHHGYTLTSKILFKDVVETINKHAFVKNEFPVILSIENHCSIQQQRKIAQYLKG
                     IFQDKLDLSSVDTGECRQLPSPQSLKGKILVKGKKLPYHLGDDAEEGEVSDEDSADEI
                     EDECKFKLHYSNGTTEHQVESFIRKKLDSLLKESQIRDKEDPDSFTVRALLKATHEGL
                     NAHLKQNLDVKESGKKSHGRSLMANFGKHKKTPKSRSKSYSTDDEEDTLQNPGKEGGQ
                     LYRLGRRRRTMKLCRELSDLVVYTNSVAAQDIVDDGTTGNVLSFSETRAHQVVQQKSE
                     QFMIYNQKQLTRIYPSAYRIDSSNFNPLPYWNAGCQLVALNYQSEGRMMQINRAKFKA
                     NGNCGYILKPQQMCKGTFNPLSGDPLPANPKKQLILKVISGQQLPKPPDSMFGDRGEI
                     IDPFVEVEIIGLPVDCCKDQTRVVDDNGFNPVWEETLTFTVHMPEIALVRFLVWDHDP
                     IGRDFVGQRTVTFSSLVPGYRHVYLEGLTEASIFVHITINEIFGKNRQLQGLKGLFNK
                     NPRHGSSENNSHYVRKRSIGDRILRRTASAPAKGRKKSKVGFQEMVEIKDSVCEATRD
                     QDGVLRRTTRSLQLRPVSMPVDKNLLGALSLPISEAAKNTDGKENYLAEDKDDGRKGP
                     ATIKDPHFSNFNKKLSSSSSALLHKDAKNQGPTASVSNPEQCGGLGLKSGRIKPHMTN
                     DCQENRSPQNFLSPRKHLALDPATKGLQDLHGMRTDEKEQERAKGFVGRKSTQSESVL
                     SQSSLEVENLEGSKAKGRAATSFSLSDVSALCSDIPDLHSTAILQDTEISDLINDVTL
                     TNANESGSSISALIGQFEESNHRANVAVVSRLLSTSGTSEGVALPVALGLQTPIKNGF
                     SQGKHKASFLCSSPELNKPSSAETTKLANNTVACGVIGSPISTPKPGDDASDKAKTRV
                     TEDNLPDSPDAFPGQFPQSPTHGEDHRQVMSSPALSMPLAMEDTTADPALCINSEESS
                     LVEIDGDSESLSLTACDYGEEALSQLVSPLKLQQSQETVEHIQKGLSNGYCKETLLPS
                     EIFNNIPGVKNQSISHLTYQGAGFVYNHFSSSDAKTNQICGPQQPRAPDMHVPTPTPS
                     THAPLAALKLPSPCKSKSLGDLTSEDIACNFESKYQCISRSFVTNSIRDKSVTMKTKS
                     FEPLDALTEQLRKLVSFDQEDSCQGLYSKQDVNQCPRALVRKLSSRSQSRVRNIASRA
                     KEKQEAGKQKAMTQNPRGGVVLRSKPPAPTLAVNRHSTGSYIASYLRNMKASGLEGRG
                     IPEGACTALRYGYMDQFCSDNSVLQTEPSSEDKPEIYFLLRL"
     exon            1..136
                     /gene="Plch1"
                     /gene_synonym="Plcl3; RGD1561991"
                     /inference="alignment:Splign:2.1.0"
     exon            137..380
                     /gene="Plch1"
                     /gene_synonym="Plcl3; RGD1561991"
                     /inference="alignment:Splign:2.1.0"
     exon            381..510
                     /gene="Plch1"
                     /gene_synonym="Plcl3; RGD1561991"
                     /inference="alignment:Splign:2.1.0"
     exon            511..681
                     /gene="Plch1"
                     /gene_synonym="Plcl3; RGD1561991"
                     /inference="alignment:Splign:2.1.0"
     exon            682..775
                     /gene="Plch1"
                     /gene_synonym="Plcl3; RGD1561991"
                     /inference="alignment:Splign:2.1.0"
     exon            776..979
                     /gene="Plch1"
                     /gene_synonym="Plcl3; RGD1561991"
                     /inference="alignment:Splign:2.1.0"
     exon            980..1100
                     /gene="Plch1"
                     /gene_synonym="Plcl3; RGD1561991"
                     /inference="alignment:Splign:2.1.0"
     exon            1101..1272
                     /gene="Plch1"
                     /gene_synonym="Plcl3; RGD1561991"
                     /inference="alignment:Splign:2.1.0"
     exon            1273..1380
                     /gene="Plch1"
                     /gene_synonym="Plcl3; RGD1561991"
                     /inference="alignment:Splign:2.1.0"
     exon            1381..1542
                     /gene="Plch1"
                     /gene_synonym="Plcl3; RGD1561991"
                     /inference="alignment:Splign:2.1.0"
     exon            1543..1614
                     /gene="Plch1"
                     /gene_synonym="Plcl3; RGD1561991"
                     /inference="alignment:Splign:2.1.0"
     exon            1615..1706
                     /gene="Plch1"
                     /gene_synonym="Plcl3; RGD1561991"
                     /inference="alignment:Splign:2.1.0"
     exon            1707..1804
                     /gene="Plch1"
                     /gene_synonym="Plcl3; RGD1561991"
                     /inference="alignment:Splign:2.1.0"
     exon            1805..1984
                     /gene="Plch1"
                     /gene_synonym="Plcl3; RGD1561991"
                     /inference="alignment:Splign:2.1.0"
     exon            1985..2092
                     /gene="Plch1"
                     /gene_synonym="Plcl3; RGD1561991"
                     /inference="alignment:Splign:2.1.0"
     exon            2093..2217
                     /gene="Plch1"
                     /gene_synonym="Plcl3; RGD1561991"
                     /inference="alignment:Splign:2.1.0"
     exon            2218..2302
                     /gene="Plch1"
                     /gene_synonym="Plcl3; RGD1561991"
                     /inference="alignment:Splign:2.1.0"
     exon            2303..2449
                     /gene="Plch1"
                     /gene_synonym="Plcl3; RGD1561991"
                     /inference="alignment:Splign:2.1.0"
     exon            2450..2529
                     /gene="Plch1"
                     /gene_synonym="Plcl3; RGD1561991"
                     /inference="alignment:Splign:2.1.0"
     exon            2530..2884
                     /gene="Plch1"
                     /gene_synonym="Plcl3; RGD1561991"
                     /inference="alignment:Splign:2.1.0"
     exon            2885..5623
                     /gene="Plch1"
                     /gene_synonym="Plcl3; RGD1561991"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgagtgtaa tgcagtccgg gacacagatg atcaagctga agcgtggcac caaaggtctc
       61 gttcgcctct tttacctgga tgaacaccgg acccgccttc gatggcgacc ctctaggaag
      121 agtgagaagg caaaaatact tattgattcc atctacaaag tcaccgaggg caggcagtct
      181 gaaattttcc acagacaggc tgaggggaac tttgatccca gctgctgctt taccatctac
      241 catggcaacc acatggagtc cctggacctc attacctcca acccagagga ggcacgcacc
      301 tggatcacgg gcctcaagta tctgatggct ggcatcagtg atgaagactc ccttgccaag
      361 aggcaaagga cccatgacca atgggtgaag cagacctttg aggaggctga taagaatggt
      421 gatggcttat tgaatattga agagattcac cagctgatgc ataaactaaa tgtcaatctg
      481 cctcgaagaa aagtcaggca aatgtttcag gaagcggaca cagatgagaa tcaggggacc
      541 ttgacatttg aagagttctg cgttttttac aaaatgatgt cattgagacg agacctctat
      601 ttgctgctct tgagctacag tgacaagaaa gaccacctta ctgtggagga gctagctcag
      661 ttcttgaagg tggaacaaaa gatgagtaat gtcacactgg actattgtct ggacgtcata
      721 aagaagttcg aagtttctga agaaaacaaa gtgaaaaacg tcctcggtat agaaggtttc
      781 acgaacttca tgcgtagccc tgcttgtgat gtatttaacc ctttgcacca tgaagtatac
      841 caagacatgg atcagcctct ctgcaattac tacattgctt cttctcataa cacatacctg
      901 actggggacc agctcctttc tcaatccaaa gtggacatgt atgcacgggt gctacaagag
      961 ggatgtcgat gcgtggaagt tgactgttgg gatggcccag atggagagcc agtggtccac
     1021 catggttata ctctcacttc aaaaattctc ttcaaagatg ttgtggagac catcaacaag
     1081 catgcatttg ttaaaaatga gtttcccgtt atactgtcca ttgagaacca ctgcagtatt
     1141 cagcagcaga ggaagattgc tcagtacctg aaaggaatat tccaggacaa actggacctg
     1201 tcatctgtag acacaggaga gtgcaggcag cttccaagcc ctcagagtct gaaaggcaaa
     1261 atcctggtga agggcaagaa gttgccatat caccttgggg atgatgcaga ggaaggagaa
     1321 gtgtccgatg aggacagtgc agatgaaatt gaagatgaat gcaagttcaa gctgcattat
     1381 agtaacggga ccactgagca ccaggtagaa tctttcatac ggaaaaagct ggactcactg
     1441 ttgaaggagt ctcagattcg agacaaggaa gacccagaca gtttcacagt gagggcgtta
     1501 ctcaaggcta cacatgaagg cttaaatgca cacctgaagc agaacctgga tgtgaaggaa
     1561 agtggaaaga agtcccatgg gcgatccctg atggccaact ttgggaaaca caagaaaact
     1621 ccaaaatcac gttctaaatc ctatagtact gatgatgagg aagatacact acagaatcct
     1681 ggcaaggagg gaggccagct gtacaggctg ggccgccgaa ggagaaccat gaaactctgc
     1741 agagagctct cggacttggt ggtgtacaca aactctgtgg cagcccagga tattgtggat
     1801 gatgggacca cagggaatgt gttgtccttc agtgaaacaa gagcacatca agtggttcag
     1861 cagaagtcag agcagttcat gatctacaac caaaaacagc tcacgaggat ttacccctct
     1921 gcctaccgca tcgattccag taacttcaac cctctgccct actggaatgc gggctgccag
     1981 ctagtggctc tgaactacca gtctgaaggg cgaatgatgc agataaatcg agcaaaattc
     2041 aaagcaaacg gcaactgtgg ctacattctc aagccccagc aaatgtgcaa aggaacattc
     2101 aaccctttgt ctggtgaccc acttcctgcc aaccccaaaa aacagctcat actgaaagtg
     2161 atcagtggac agcaactccc caaaccccct gactctatgt ttggagaccg aggcgagatc
     2221 attgaccctt ttgttgaagt tgaaattatt gggcttcctg tagactgttg caaggaccaa
     2281 actcgtgtgg tggatgacaa tggatttaac cctgtgtggg aagaaaccct aacttttaca
     2341 gttcacatgc cagaaatagc tttggttcga tttcttgtgt gggatcatga tcctatcgga
     2401 agagactttg tgggacaacg gaccgtgacc ttcagcagcc tcgtgcctgg ctaccggcat
     2461 gtctacctgg aaggcctcac agaagcgtct attttcgttc acataacaat caatgagatc
     2521 tttggaaaga acagacagct ccaaggcttg aagggactgt tcaataagaa tcccaggcac
     2581 ggttcttcag aaaataactc ccattatgtt cggaagcgat caattggaga tagaattctg
     2641 cgacgtacag ccagtgctcc agccaaaggc aggaaaaaga gcaaagtggg cttccaagaa
     2701 atggttgaga taaaagattc tgtctgtgag gctacaagag atcaagatgg tgtcctgagg
     2761 aggaccacac ggagtctgca actgcgccct gtctctatgc ctgttgacaa gaaccttctg
     2821 ggggctttgt cactgcctat ctctgaagca gcaaaaaaca cagatggaaa agaaaactat
     2881 ctggcagagg acaaggatga tggaagaaag gggccagcaa ctataaaaga cccacatttt
     2941 tccaatttca acaaaaagtt atcctcctcc tccagtgccc tcctccacaa agatgccaaa
     3001 aaccaagggc caacagccag tgtatcaaac ccagaacagt gtggaggact aggtttaaag
     3061 agtgggagaa tcaaaccaca tatgacaaat gattgccagg aaaaccgcag tccccaaaac
     3121 ttcctctctc caaggaagca tttggcactt gatcccgcaa ccaagggact gcaagatctg
     3181 catggaatga gaactgatga aaaggagcag gagcgtgcca agggctttgt gggaaggaaa
     3241 agcacgcaga gcgaaagtgt tctttctcaa agttctctgg aggtggagaa tctggaaggc
     3301 agcaaggcca agggcagagc tgcaacgtcc ttttctctct ccgatgtctc tgcactctgt
     3361 tctgacattc ctgatttgca ttcaactgcc attctgcagg acactgaaat ttccgatctc
     3421 attaatgatg tgactttaac aaatgcaaat gagtcgggca gttccatctc agcactgatc
     3481 ggccagtttg aagagagcaa ccatcgggct aacgttgccg tggtttctcg tctccttagc
     3541 accagtggga catcagaagg tgttgctttg ccagtcgcgt tgggcctaca aacacccatc
     3601 aagaatggct tttcccaggg gaagcacaag gcctccttct tgtgctcatc tcctgagttg
     3661 aacaagccct ctagtgcgga aaccaccaaa ctggcaaata acacagttgc ctgtggagtg
     3721 attggctctc ccatctctac accaaagcca ggtgatgacg cttctgataa agccaagaca
     3781 agggtcacgg aagacaacct gcctgattcc cctgatgctt ttcctggcca gtttccccaa
     3841 agccccaccc acggagagga ccataggcaa gtgatgagca gccctgctct ctccatgccg
     3901 ttggccatgg aagatacaac agctgacccc gctctctgta taaattctga ggagagcagt
     3961 cttgtggaaa ttgatggaga ctctgaaagc ctatctctaa cagcctgtga ctatggggaa
     4021 gaagctctga gtcaacttgt ttctccacta aaactgcagc agagccagga gacggtggaa
     4081 cacatccaga aaggcttgag caatggctac tgtaaagaga ctctcctccc ttctgaaata
     4141 ttcaacaata ttccaggtgt caaaaatcag agtatttctc atctaaccta tcagggtgct
     4201 ggctttgtgt ataaccattt ctcaagttca gatgcaaaaa cgaaccaaat ctgtgggccc
     4261 cagcagccta gggctccaga tatgcatgtc cctacaccca caccctcgac acatgcccct
     4321 ttggctgctt tgaaactgcc aagcccatgc aaatccaaaa gtctggggga cttaacatca
     4381 gaggacattg cctgcaattt tgaaagcaaa taccaatgta ttagtaggag tttcgtgaca
     4441 aacagcatta gagacaagag cgtgactatg aagacaaagt cattcgagcc tctagatgcc
     4501 ctaactgaac agctccggaa gctggtgtcc tttgaccaag aagacagctg tcaagggtta
     4561 tactcaaagc aggatgtcaa tcagtgtccc agggccttag tcagaaagtt gtcctctaga
     4621 agtcagagca gagttcgcaa cattgctagt cgtgccaagg agaagcagga agctggcaag
     4681 caaaaagcta tgactcagaa ccccagagga ggagtggtcc ttagaagtaa accgccagct
     4741 cctactctgg ctgtgaaccg tcactccacg ggctcataca ttgcaagcta cctgaggaac
     4801 atgaaagcta gtggcctaga aggtcgcggc atcccagagg gagcatgcac agcccttcgc
     4861 tacggctaca tggaccagtt ctgttcagac aattcagttc tgcagactga gccaagcagt
     4921 gaagataaac ccgaaattta ttttcttttg aggctttgaa ctatataaag ctacatcttc
     4981 attgtttaca tgatattctc taagatgtta gttttttttt ccattgtcag taaatatgat
     5041 actgggcttg gaaatgattt ccaaatgtac ttttaaactt gtattttggt ctcctgttgc
     5101 tcatgcattt gtacatagat tctgtgacat gtccccggaa cccacgacct ttccccggag
     5161 gtattgtaaa ctgtgtcagt ataaaatgtg tgcatgacct ccatgtgaac cttctcagca
     5221 gcttgggtca cagtgtgcat atgttgcaca gaaatgtttt tccccgtgtc ctccgatcac
     5281 agccccagag gctgtcgccg ttactcacta ggtgttgagc tgattgagtt taaactttga
     5341 gaaccataaa gggatggttt ctttgttggg agctacattt tccttctgaa ttgagagaca
     5401 cagattcact tttataatcc acttaagacc attgttttaa gtagttacct tgccctttct
     5461 gagttccaca tgccaccaaa gtgggaattc cataaagatg gacagcctct ctccaacccc
     5521 caaagtccct tttagaatag gccgtgagga agaaagtgaa cttctgtata tagggacaaa
     5581 ttagtttgtt ttgcaataaa ttttgttaca tattttttgc taa
//
