LOCUS       NM_001401809            5442 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus PLAG1 like zinc finger 2 (Plagl2), mRNA.
ACCESSION   NM_001401809 XM_006235285
VERSION     NM_001401809.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5442)
  AUTHORS   Hasson,S.A., Kane,L.A., Yamano,K., Huang,C.H., Sliter,D.A.,
            Buehler,E., Wang,C., Heman-Ackah,S.M., Hessa,T., Guha,R.,
            Martin,S.E. and Youle,R.J.
  TITLE     High-content genome-wide RNAi screens identify regulators of parkin
            upstream of mitophagy
  JOURNAL   Nature 504 (7479), 291-295 (2013)
   PUBMED   24270810
REFERENCE   2  (bases 1 to 5442)
  AUTHORS   Van Dyck,F., Braem,C.V., Chen,Z., Declercq,J., Deckers,R.,
            Kim,B.M., Ito,S., Wu,M.K., Cohen,D.E., Dewerchin,M., Derua,R.,
            Waelkens,E., Fiette,L., Roebroek,A., Schuit,F., Van de Ven,W.J. and
            Shivdasani,R.A.
  TITLE     Loss of the PlagL2 transcription factor affects lacteal uptake of
            chylomicrons
  JOURNAL   Cell Metab 6 (5), 406-413 (2007)
   PUBMED   17983586
REFERENCE   3  (bases 1 to 5442)
  AUTHORS   Yang,M.C., Weissler,J.C., Terada,L.S., Deng,F. and Yang,Y.S.
  TITLE     Pleiomorphic adenoma gene-like-2, a zinc finger protein,
            transactivates the surfactant protein-C promoter
  JOURNAL   Am J Respir Cell Mol Biol 32 (1), 35-43 (2005)
   PUBMED   15361364
REFERENCE   4  (bases 1 to 5442)
  AUTHORS   Mizutani,A., Furukawa,T., Adachi,Y., Ikehara,S. and Taketani,S.
  TITLE     A zinc-finger protein, PLAGL2, induces the expression of a
            proapoptotic protein Nip3, leading to cellular apoptosis
  JOURNAL   J Biol Chem 277 (18), 15851-15858 (2002)
   PUBMED   11832486
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Feb 25, 2022 this sequence version replaced XM_006235285.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643429.14024.1,
                                           SRR26643289.11298.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMN12840105 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-103               JAXUCZ010000003.1  162168646-162168748 c
            104-476             JAXUCZ010000003.1  162163213-162163585 c
            477-5442            JAXUCZ010000003.1  162155554-162160519 c
FEATURES             Location/Qualifiers
     source          1..5442
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q41"
     gene            1..5442
                     /gene="Plagl2"
                     /note="PLAG1 like zinc finger 2"
                     /db_xref="GeneID:296281"
                     /db_xref="RGD:1307999"
     exon            1..103
                     /gene="Plagl2"
                     /inference="alignment:Splign:2.1.0"
     exon            104..476
                     /gene="Plagl2"
                     /inference="alignment:Splign:2.1.0"
     CDS             217..1707
                     /gene="Plagl2"
                     /note="pleiomorphic adenoma gene-like 2"
                     /codon_start=1
                     /product="zinc finger protein PLAGL2"
                     /protein_id="NP_001388738.1"
                     /db_xref="GeneID:296281"
                     /db_xref="RGD:1307999"
                     /translation="MTTFFTSVPPWIQDAKQEEEVGWKLVPRPRGREAESQVKCQCEI
                     SGTPFSNGEKLRPHSLPHPEQRPYSCPQLHCGKAFASKYKLYRHMATHSAQKPHQCMY
                     CDKMFHRKDHLRNHLQTHDPNKEALHCSECGKNYNTKLGYRRHLAMHAASSGDLSCKV
                     CLQTFESTQALLEHLKAHSRRVAGGAKEKKHPCDHCDRRFYTRKDVRRHLVVHTGRKD
                     FLCQYCAQRFGRKDHLTRHVKKSHSQELLKIKTEPVDMLGLLSCSSTVSVKEELSPVL
                     CMASRDMMGAKAFPGMLPMGMYGAHIPTMPSAGMPHSLVHNTLPMGMSYPLESSPISS
                     SAQLPPKYQLGSTSYLPDKLPKVEVDSFLAELPGSLSLSSAEPQPASPQPAAAAALLD
                     EALLTKSPANLSEALCAANVDFSHLLGFLPLNLPPCNPPGATGGLVMGYSQAEAQPLL
                     TTLQAQPQDSAGAGGPLNFGPLHSLPPVFTSGLSTTTLPRFHQAFQ"
     exon            477..5442
                     /gene="Plagl2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acaatgcacc gcacaatggc ccgaccgccg ccactaccgg ggcctgagcg ggcctggcgg
       61 agcccgagcg cggcccggcc cgcagcgcgg ggtcccgagc gcagtgaaga gactgttttc
      121 tgaaggctgc gttggaggct gtgaccgagc agagagtcca tgtgaactga tggggaggct
      181 ttctgaataa catggccttt tgccattagc cttgccatga ccacattttt caccagcgtc
      241 cctccctgga ttcaagatgc aaagcaggag gaggaagtgg gctggaaact agttcccagg
      301 cctcggggcc gggaggcaga gagtcaagtg aagtgccaat gtgaaatctc ggggacacca
      361 ttctcaaatg gggagaagct aaggcctcac agcctccccc atccggagca gagaccatac
      421 agctgtcctc agctgcactg tggcaaggct tttgcctcca agtacaagct gtataggcac
      481 atggccaccc actcagccca gaaaccccac cagtgcatgt actgtgacaa gatgtttcac
      541 cgaaaggacc atctgcgcaa ccacttgcag acccatgacc ccaacaagga ggccctccac
      601 tgctctgaat gtggtaagaa ttataataca aagctggggt accgtcgcca cctggccatg
      661 catgctgcca gcagtggtga tctcagctgc aaggtgtgcc tgcagacctt cgagagtacc
      721 caggccctac tggagcacct gaaggctcac tcacgccggg tagcaggagg tgctaaggag
      781 aagaagcacc cctgtgacca ctgtgaccgg cggttttata ctcggaagga tgttcgacgg
      841 cacctagtgg tgcacacagg tcgtaaggac ttcctgtgtc agtactgtgc ccagaggttt
      901 ggccgcaagg atcatctgac acgccatgtc aagaagagcc actcacagga actgctcaag
      961 atcaagacag agccagtgga tatgttaggc ttacttagct gcagctctac agtcagtgta
     1021 aaggaagagc tgagccctgt gctttgcatg gcctctcggg acatgatggg ggctaaggcc
     1081 tttcctggca tgttgcccat gggtatgtat ggtgcccaca tccctaccat gcccagtgcg
     1141 ggcatgccac actccctggt gcacaacaca ctgcccatgg gtatgagtta ccctctggaa
     1201 tcttctccta tctcctcctc agctcagctc cctccaaaat accagcttgg atctacctca
     1261 tacttgcccg acaaactgcc caaagtggag gtggatagtt ttctggcaga gcttcctgga
     1321 agcctgtctc tctcatcggc tgaacctcag cccgcctcac ctcagccggc ggcagctgca
     1381 gccctcctag atgaagcact gctcaccaag agtcccgcca acctctctga ggccctctgc
     1441 gctgctaacg tggacttctc ccacttactg ggctttcttc cgctcaacct acccccatgt
     1501 aacccaccag gggccacagg aggcttggtc atgggctact cccaagctga ggcacagcct
     1561 ttgctcacca ctttgcaggc tcagcctcaa gattccgctg gagctggggg acccctgaac
     1621 tttgggcctc tgcactcctt gcctcctgtc ttcacctctg gcctgagtac caccaccctg
     1681 cctcgtttcc accaagcatt ccagtagccc ccatgaagat ccccccaact cagttctttg
     1741 cttctgccag ggagcctaag tacccacccc gtccacttcc cccatgaagg cagctgagct
     1801 ttcagagctg ggttcaaaaa gagaattcta gtatctatat ggagcacttg gtttgggggt
     1861 tcaggctcca ggatcagtct agagggatcc ttgaacccag ccccatgaac aatctatcat
     1921 aggactttca ggtattttta cttttatttt ttgatctgaa ctgggagcta tatttagccc
     1981 tctgcctctc caaagcgtca gaaccacctt cagtctggag aaggggaagc ctcttggaga
     2041 cagagggttt caccttatat gacctcaaga gaaatagcct aagaagcctg ccttccggtc
     2101 ccaacctgca gacactccag cagttgactg ttgagtcctt gctgcggaag gtctcttgac
     2161 tatcacctgc ttccagctac caggcaagaa agagggcctc tagtctcagc catcccaccc
     2221 catctaccaa cagctccact tcagtcagtg ttgttcagca acggtaccgt ttacacagtc
     2281 acctccgaca caccatttca cctccctcgc cacactgtta gccttagagt gattgcagtg
     2341 aacactgttt acacaccgtg aatccattcc caccagtcca tttcagttgc caccagtctg
     2401 aaccactcgg tacctggtgt taactggagc cctgtttaca aggcggagtc gggtcttgct
     2461 gacttctctt cacttgaggt cacatttttt cccccgtggg gaaataaact gactttggac
     2521 tgcttcagtt tctgccatct tccatgactg cttctattcc tgccttccac ggcagtgccc
     2581 acaggagata ggcaagaaga ttggagcagc tttctcacag gtctgcaatt gggttttctc
     2641 caagtacatc atgacacctt cgtcctcctg aactggagag gggaagaaat gaaaggcatc
     2701 ccatatgcac catttcctca gtccctaacc caccctggac atcatgagct gttatttgtc
     2761 ttggaaggag gggttctggg ctttgggctg gatagcagag gagaggggtg agcccttcgt
     2821 ttgtttccct tctgcttgtc cttttccagg acataatgga actgtcggaa gaagagtttc
     2881 tagaaagtta ggattgggca gatagttgag tcctaatcta tcaaatcatt gttgcctctc
     2941 ataccaaaat gttcttaccc agtgtccctt ccccttctct gctttgcagt actcatggac
     3001 tctgggcatg gtacattgtt gtctttgctc tccactcagc atggtcccct cagttgctcc
     3061 tagtatctag caatgtttct tgcaagaaat tactagttct tctgctgact tggagctttc
     3121 tgtcattgac agtacagccc ttgcccagaa ccagctgaac aattcctaat ccatttcatc
     3181 tcggttctgt atgggttttt cccatgcatg gaagggaggc agctcaggga ccaccactgt
     3241 gggacctttt gagacacctc tctgattcag aaacacactt ctacctcttt actgttaact
     3301 cctacagatg tagccagcaa cctgggcact tgtgttagtg gtgccttttg ctggcttctc
     3361 cactaggatt tcaggacaga ctacctagga actgcctcag tctcccacca gttcttccct
     3421 gcccctctct tctgtctaga ttcacttcag tttattgttg ggaactgtgc aggtccaaga
     3481 cctggactcc tgcttcagcc caggccagta ctccttgttt gaggtgaaag ccttcagttt
     3541 agctccctgg cccttatatg gaagcaatgt ggagtgaatg agcatgtttt gatttaagca
     3601 aggtagcttg gaataccttt ttaaaagaca actggatata aatatgtctg acaggattgg
     3661 aatcagacta tgtgatttgc ttctaaagat tagtttcaat gagtcccagg gactaattaa
     3721 ggtttatttt taaaagcgtc taccttggta cgcaaccatc tcctgcatgc tatgcatgtt
     3781 gttgggactc gtattacagg aagtggcatg tgagaatcca agtgggactc actgctgcca
     3841 ttctccttgt gtttggtctt cactagaccc aggcccctct ctacccttcc taccacctcc
     3901 ctatagcctc agtctcagaa gccagtagcc tcaagccaca ggacatagtg ttctgggctg
     3961 tctgaggagg acccgtcctc ctgagcttga ccttctcttg gtgctcatag gacagcagag
     4021 catcaactgt agatctggta atggggcctt gttcccacct ctggtctttc ctccttgtct
     4081 tttcctgtct atccttcctg tttctctaca tttctcagtc ttcactctaa ggacttttcc
     4141 tgtcactgtg aactttgctg gttatctgcc ttcaattttt ggaccacaaa ccaccctgca
     4201 gcttcttaaa tctttctcca acctaccacc caaaagagcc tttttggcca ttttttttaa
     4261 aagataggaa taattttatc ctgtacttgg tgcccagact cattgaagta ccccttatga
     4321 ggccaagaga gccagagggg catatgccca ggacaggagc catggcatgt ggcatagacc
     4381 aatcagggac cagaaaagag tgatgtccct ttccttgcta tgtccttaag cctgtcagca
     4441 gtgaactgac tgcaagggga cagcacctct tcacctgcac agcagcttgt cagagttgag
     4501 aactgtcctg gggccaggga ctaacatgcc caggggtcgg ctcagaggat cctagcacca
     4561 tcttaagcag gtgggaggca gggcagggtg caccagcgtg tctttccccg acttcacatg
     4621 gtgttttgtt aatgcaaatc cgggaagcag gtgtgattgc tttttgctca tagatattgt
     4681 cctaagttga aatcccctaa acctccctta gtagccttta agtttcccct tccctttttg
     4741 gtagctgttt tctctacccc ttctccatga ttaaaaaaca taaaaacaaa aatgcaaaaa
     4801 aaacaaaaaa aaacaggttg tattatacag gatcaatatt ttgcttttta acaaggatat
     4861 ttatgtaata agaaactttg ccttaggcag gtgttggcca gaaaagtcca gatttctctg
     4921 tgacctcacc ctggcctctc ctggagctct gaacctgctg tggaaggaag tggctgcaac
     4981 cactggagag tggggtctgt ggtgtggaaa gggtgttcac tgtgtgaccc tggactgtgt
     5041 ggagctgttc ctgtcacctc gcttcagatg ttacttggcg tcctccacca gttctcccat
     5101 gcgcacctct gcatgtctgg cactagaatt cctgaacact acttcacacc ctccctcact
     5161 cccagtttgt tgaagctcta gagccactcc tgaatgccag attatttaaa gaaagaaaaa
     5221 tacaagacaa aaaccttcta gcactttgta aacacagtaa ataacctctt ggagtatttt
     5281 tggctttata taaaacaagg tttttaattg taaaatataa gtgccattag aaaatgcaca
     5341 gggcgtatct ttgttaaagt agatttttca atgttttaca gaattaattt tcaaaaaaaa
     5401 gtttttataa tgaagttgtt tattaaaaac ttctgaatga tg
//
