LOCUS       NM_017060                696 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus phospholipase A and acyltransferase 3 (Plaat3),
            mRNA.
ACCESSION   NM_017060 XM_346574
VERSION     NM_017060.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 696)
  AUTHORS   Archambaud,C., Nahori,M.A., Soubigou,G., Becavin,C., Laval,L.,
            Lechat,P., Smokvina,T., Langella,P., Lecuit,M. and Cossart,P.
  TITLE     Impact of lactobacilli on orally acquired listeriosis
  JOURNAL   Proc Natl Acad Sci U S A 109 (41), 16684-16689 (2012)
   PUBMED   23012479
REFERENCE   2  (bases 1 to 696)
  AUTHORS   Uyama,T., Ikematsu,N., Inoue,M., Shinohara,N., Jin,X.H., Tsuboi,K.,
            Tonai,T., Tokumura,A. and Ueda,N.
  TITLE     Generation of N-acylphosphatidylethanolamine by members of the
            phospholipase A/acyltransferase (PLA/AT) family
  JOURNAL   J Biol Chem 287 (38), 31905-31919 (2012)
   PUBMED   22825852
REFERENCE   3  (bases 1 to 696)
  AUTHORS   Uyama,T., Ichi,I., Kono,N., Inoue,A., Tsuboi,K., Jin,X.H.,
            Araki,N., Aoki,J., Arai,H. and Ueda,N.
  TITLE     Regulation of peroxisomal lipid metabolism by catalytic activity of
            tumor suppressor H-rev107
  JOURNAL   J Biol Chem 287 (4), 2706-2718 (2012)
   PUBMED   22134920
REFERENCE   4  (bases 1 to 696)
  AUTHORS   Han,B.G., Cho,J.W., Cho,Y.D., Kim,S.Y., Yoon,H.J., Song,H.K.,
            Cheong,H.K., Jeon,Y.H., Lee,D.K., Lee,S. and Lee,B.I.
  TITLE     Expression, purification and biochemical characterization of the
            N-terminal regions of human TIG3 and HRASLS3 proteins
  JOURNAL   Protein Expr Purif 71 (1), 103-107 (2010)
   PUBMED   20100577
REFERENCE   5  (bases 1 to 696)
  AUTHORS   Jaworski,K., Ahmadian,M., Duncan,R.E., Sarkadi-Nagy,E.,
            Varady,K.A., Hellerstein,M.K., Lee,H.Y., Samuel,V.T., Shulman,G.I.,
            Kim,K.H., de Val,S., Kang,C. and Sul,H.S.
  TITLE     AdPLA ablation increases lipolysis and prevents obesity induced by
            high-fat feeding or leptin deficiency
  JOURNAL   Nat Med 15 (2), 159-168 (2009)
   PUBMED   19136964
REFERENCE   6  (bases 1 to 696)
  AUTHORS   Kwitek,A.E., Gullings-Handley,J., Yu,J., Carlos,D.C., Orlebeke,K.,
            Nie,J., Eckert,J., Lemke,A., Andrae,J.W., Bromberg,S., Pasko,D.,
            Chen,D., Scheetz,T.E., Casavant,T.L., Soares,M.B., Sheffield,V.C.,
            Tonellato,P.J. and Jacob,H.J.
  TITLE     High-density rat radiation hybrid maps containing over 24,000
            SSLPs, genes, and ESTs provide a direct link to the rat genome
            sequence
  JOURNAL   Genome Res 14 (4), 750-757 (2004)
   PUBMED   15060019
REFERENCE   7  (bases 1 to 696)
  AUTHORS   Siegrist,S., Feral,C., Chami,M., Solhonne,B., Mattei,M.G.,
            Rajpert-De Meyts,E., Guellaen,G. and Bulle,F.
  TITLE     hH-Rev107, a class II tumor suppressor gene, is expressed by
            post-meiotic testicular germ cells and CIS cells but not by human
            testicular germ cell tumors
  JOURNAL   Oncogene 20 (37), 5155-5163 (2001)
   PUBMED   11526504
REFERENCE   8  (bases 1 to 696)
  AUTHORS   Sers,C., Emmenegger,U., Husmann,K., Bucher,K., Andres,A.C. and
            Schafer,R.
  TITLE     Growth-inhibitory activity and downregulation of the class II
            tumor-suppressor gene H-rev107 in tumor cell lines and experimental
            tumors
  JOURNAL   J Cell Biol 136 (4), 935-944 (1997)
   PUBMED   9049257
REFERENCE   9  (bases 1 to 696)
  AUTHORS   Hajnal,A., Klemenz,R. and Schafer,R.
  TITLE     Subtraction cloning of H-rev107, a gene specifically expressed in
            H-ras resistant fibroblasts
  JOURNAL   Oncogene 9 (2), 479-490 (1994)
   PUBMED   8290259
REFERENCE   10 (bases 1 to 696)
  AUTHORS   Longati,P., Bardelli,A., Ponzetto,C., Naldini,L. and Comoglio,P.M.
  TITLE     Tyrosines1234-1235 are critical for activation of the tyrosine
            kinase encoded by the MET proto-oncogene (HGF receptor)
  JOURNAL   Oncogene 9 (1), 49-57 (1994)
   PUBMED   8302603
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB613004.1 and CB794299.1.
            
            On Mar 8, 2007 this sequence version replaced NM_017060.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB613004.1, CF111032.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-539               CB613004.1         1-539
            540-696             CB794299.1         246-402
FEATURES             Location/Qualifiers
     source          1..696
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..696
                     /gene="Plaat3"
                     /gene_synonym="Hrasls3; Hrev107; HRSL3; Pla2g16; RLP-3"
                     /note="phospholipase A and acyltransferase 3"
                     /db_xref="GeneID:24913"
                     /db_xref="RGD:2829"
     exon            1..27
                     /gene="Plaat3"
                     /gene_synonym="Hrasls3; Hrev107; HRSL3; Pla2g16; RLP-3"
                     /inference="alignment:Splign:2.1.0"
     exon            28..90
                     /gene="Plaat3"
                     /gene_synonym="Hrasls3; Hrev107; HRSL3; Pla2g16; RLP-3"
                     /inference="alignment:Splign:2.1.0"
     CDS             82..564
                     /gene="Plaat3"
                     /gene_synonym="Hrasls3; Hrev107; HRSL3; Pla2g16; RLP-3"
                     /EC_number="3.1.1.4"
                     /EC_number="3.1.1.32"
                     /note="group XVI phospholipase A2; HRAS-like suppressor 3;
                     LRAT-like protein-3; Hras-revertant gene 107 (expression
                     down-regulated in HRAS-transformed rat 208F fibroblasts);
                     phospholipase A2, group XVI; group XVI phospholipase
                     A1/A2; H-rev 107 protein homolog"
                     /codon_start=1
                     /product="phospholipase A and acyltransferase 3"
                     /protein_id="NP_058756.2"
                     /db_xref="GeneID:24913"
                     /db_xref="RGD:2829"
                     /translation="MPIPEPKPGDLIEIFRPMYSHWAIYVGDGYVIHLAPPSEIPGAG
                     AASIMSALTDKAIVKKELLRDVAGKDKYQVNNKHDKEYTPLPLNKIIQRAEELVGQEV
                     LYRLTSENCEHFVNELRYGVPRSDQVRDAVKVATVTGVGLAALGLIGVMLSRNKKQKQ
                     "
     exon            91..193
                     /gene="Plaat3"
                     /gene_synonym="Hrasls3; Hrev107; HRSL3; Pla2g16; RLP-3"
                     /inference="alignment:Splign:2.1.0"
     exon            194..462
                     /gene="Plaat3"
                     /gene_synonym="Hrasls3; Hrev107; HRSL3; Pla2g16; RLP-3"
                     /inference="alignment:Splign:2.1.0"
     exon            463..696
                     /gene="Plaat3"
                     /gene_synonym="Hrasls3; Hrev107; HRSL3; Pla2g16; RLP-3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agagtttttt ctgggaccta aacaaaggca tccacggcgc tgctaagctg aagttgagcc
       61 tcacatatcc tggaaaggaa aatgcccata ccagaaccca agcctggaga tctgattgag
      121 attttccgcc ctatgtacag tcactgggcc atctatgttg gtgatggata tgtgatccac
      181 ctggctcccc caagtgaaat cccaggagct ggggcagcca gcatcatgtc tgctttgacg
      241 gacaaggcca tagtgaagaa agagctgctg cgtgatgtgg ctgggaagga caagtaccag
      301 gtcaacaaca agcacgacaa ggagtacact ccgctgcctc tgaacaagat catccagcga
      361 gctgaggagc tggtggggca ggaggtgctg tacaggctga ccagtgagaa ctgtgagcac
      421 ttcgtgaacg aactgcgtta tggagtccct cggagtgacc aggtcagaga tgccgtcaag
      481 gtggcgaccg tcactggagt gggcttggcg gccttgggcc tcattggagt catgctctca
      541 agaaacaaga aacagaagca gtgagctgaa tgactatcca gctttagggc tcttcttttg
      601 ctagagggtt ggagtttgat ttatagattc tactgcttta taattaggta tattttcaca
      661 atatacaata aaccacaaga agggaatttt catgga
//
