LOCUS       NM_001419221            1298 bp    mRNA    linear   ROD 31-MAR-2023
DEFINITION  Rattus norvegicus phospholipase A2, group IIE (Pla2g2e), mRNA.
ACCESSION   NM_001419221 XM_039109679
VERSION     NM_001419221.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1298)
  AUTHORS   Hou S, Xu T, Xu J, Qu L, Xu Y, Chen L and Liu J.
  TITLE     Structural basis for functional selectivity and ligand recognition
            revealed by crystal structures of human secreted phospholipase A2
            group IIE
  JOURNAL   Sci Rep 7 (1), 10815 (2017)
   PUBMED   28883454
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1298)
  AUTHORS   Sato H, Taketomi Y, Ushida A, Isogai Y, Kojima T, Hirabayashi T,
            Miki Y, Yamamoto K, Nishito Y, Kobayashi T, Ikeda K, Taguchi R,
            Hara S, Ida S, Miyamoto Y, Watanabe M, Baba H, Miyata K, Oike Y,
            Gelb MH and Murakami M.
  TITLE     The adipocyte-inducible secreted phospholipases PLA2G5 and PLA2G2E
            play distinct roles in obesity
  JOURNAL   Cell Metab 20 (1), 119-132 (2014)
   PUBMED   24910243
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000162.1.
            
            [WARNING] On Apr 3, 2024 this sequence was replaced by
            NM_001419221.2.
            
            On Mar 29, 2023 this sequence version replaced XM_039109679.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BE128774.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06621351, SAMN09345329
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-132               JACYVU010000162.1  65670662-65670793
            133-271             JACYVU010000162.1  65673607-65673745
            272-378             JACYVU010000162.1  65673937-65674043
            379-1298            JACYVU010000162.1  65675527-65676446
FEATURES             Location/Qualifiers
     source          1..1298
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..1298
                     /gene="Pla2g2e"
                     /note="phospholipase A2, group IIE"
                     /db_xref="GeneID:298581"
                     /db_xref="RGD:1309611"
     exon            1..132
                     /gene="Pla2g2e"
                     /inference="alignment:Splign:2.1.0"
     exon            133..271
                     /gene="Pla2g2e"
                     /inference="alignment:Splign:2.1.0"
     CDS             171..521
                     /gene="Pla2g2e"
                     /EC_number="3.1.1.4"
                     /codon_start=1
                     /product="group IIE secretory phospholipase A2"
                     /protein_id="NP_001406150.1"
                     /db_xref="GeneID:298581"
                     /db_xref="RGD:1309611"
                     /translation="MIERMTGKPALQYNDYGCYCGVGGSNWPVDQTDWCCHAHDCCYG
                     RLEKLGCDPKLEKYLFSITRDTIFCAGRTTCQRQTCECDKRAALCFRHNLGTYNRKYA
                     HYPNKLCTGPTPPC"
     exon            272..378
                     /gene="Pla2g2e"
                     /inference="alignment:Splign:2.1.0"
     exon            379..1298
                     /gene="Pla2g2e"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cagtttgagg cctcatgacc caggccagaa gccagggact gccaggagag gtctcattaa
       61 aatcaaaagg aaatgggaaa agggacctct ctcagtagac tgtgactcag agctgcaggg
      121 tgtaccaggc agcgcccctg gctggtggga acctggtcca gtttggagta atgattgaga
      181 gaatgacagg aaagcccgcc ctgcagtaca acgactacgg ctgttactgt ggtgttggtg
      241 gctccaactg gccggtggac cagacggatt ggtgctgtca cgcccatgac tgctgctatg
      301 gccgcctgga gaagctgggc tgtgatccca aactggaaaa gtacctcttc tctatcaccc
      361 gggacaccat cttctgtgct ggtagaacga cttgccagcg gcagacctgt gagtgtgaca
      421 agagagctgc cctctgcttt cgccacaacc tgggcactta taaccgcaag tatgctcact
      481 accccaacaa actgtgcact gggcccaccc caccctgctg aggtcctgct ccgctccata
      541 gccaaccccc ccaccccccg gctgctgccg tcccagacct ggagaagctc ggaatccata
      601 ttcctctcct gcaaacccat cctgcccctc agagatggtg ggcccgggtc tccggcctcc
      661 agggccacac ctggtctccc ggatcagcta aaggaaccgc gggactcaac agcgctcaca
      721 agaccctaag tctcccctgg catctcagtt ccctcttctg aataagcgaa ttcttttccc
      781 ctgtaacagt ctccattgtt cctccagact ttacacagtc acttgcattc gcccatccat
      841 ccatccatcc atccagtcat attttgagca cctatcctgg gccagcacaa tgctaagcac
      901 tgccacacag tggggacaga tgcacacagt ggctcctgtc tgccgggcag caataaatcc
      961 tttattttct atagcagtga attcctatgt ttccataccc tgaaactcga gctgtgaaac
     1021 aacaacccga ccctgagctc acacagagac ccacccacct gcctctgcct cctgagggct
     1081 gaggtgaaca agtgccagca tgtccggatc ccgatctctc tctctctctc tctctctctc
     1141 tctctctctc tctctctctc tctctctctc tccctctctc tctctctctc tcttccgctc
     1201 tctctctctc cagtcttatc caagactgcc atggttctct ctggaaggaa catttctggc
     1261 cagatggctt actatgagaa gcattaaaaa aaaaaaaa
//
