LOCUS       NM_001389236            3290 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus protein kinase N3 (Pkn3), mRNA.
ACCESSION   NM_001389236 XM_006233773
VERSION     NM_001389236.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3290)
  AUTHORS   Lachmann,S., Jevons,A., De Rycker,M., Casamassima,A., Radtke,S.,
            Collazos,A. and Parker,P.J.
  TITLE     Regulatory domain selectivity in the cell-type specific
            PKN-dependence of cell migration
  JOURNAL   PLoS One 6 (7), e21732 (2011)
   PUBMED   21754995
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Dec 1, 2020 this sequence version replaced XM_006233773.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643429.11064.1,
                                           SRR26643290.10903.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-392               JAXUCZ010000003.1  33748670-33749061
            393-624             JAXUCZ010000003.1  33749780-33750011
            625-770             JAXUCZ010000003.1  33750203-33750348
            771-882             JAXUCZ010000003.1  33750783-33750894
            883-1010            JAXUCZ010000003.1  33750971-33751098
            1011-1194           JAXUCZ010000003.1  33751261-33751444
            1195-1341           JAXUCZ010000003.1  33753176-33753322
            1342-1451           JAXUCZ010000003.1  33753399-33753508
            1452-1595           JAXUCZ010000003.1  33753619-33753762
            1596-1671           JAXUCZ010000003.1  33755222-33755297
            1672-1834           JAXUCZ010000003.1  33755379-33755541
            1835-1931           JAXUCZ010000003.1  33755653-33755749
            1932-1999           JAXUCZ010000003.1  33755849-33755916
            2000-2063           JAXUCZ010000003.1  33757396-33757459
            2064-2155           JAXUCZ010000003.1  33757610-33757701
            2156-2332           JAXUCZ010000003.1  33758013-33758189
            2333-2395           JAXUCZ010000003.1  33759330-33759392
            2396-2472           JAXUCZ010000003.1  33759498-33759574
            2473-2615           JAXUCZ010000003.1  33760239-33760381
            2616-2723           JAXUCZ010000003.1  33760466-33760573
            2724-2804           JAXUCZ010000003.1  33760732-33760812
            2805-3290           JAXUCZ010000003.1  33760920-33761405
FEATURES             Location/Qualifiers
     source          1..3290
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3p12"
     gene            1..3290
                     /gene="Pkn3"
                     /gene_synonym="LRRGT00147"
                     /note="protein kinase N3"
                     /db_xref="GeneID:296619"
                     /db_xref="RGD:1305921"
     exon            1..392
                     /gene="Pkn3"
                     /gene_synonym="LRRGT00147"
                     /inference="alignment:Splign:2.1.0"
     CDS             378..3017
                     /gene="Pkn3"
                     /gene_synonym="LRRGT00147"
                     /EC_number="2.7.11.13"
                     /codon_start=1
                     /product="serine/threonine-protein kinase N3"
                     /protein_id="NP_001376165.1"
                     /db_xref="GeneID:296619"
                     /db_xref="RGD:1305921"
                     /translation="MEHRKPRTGQRAPEDEKEMIRRAIQKELKIKEGMENMRRVATDR
                     RHLGHVQQLLRASNRRLEQLHGELRELHAQVLLPAPAHEPMTSGPQPRAEQSRARLLE
                     ALHRQLEVELKVKQGAENMIHTCASGTPKERKLLAAAQQMLKDSQLKVALLRMKISGL
                     EASGSPEPGPDLLAEELQHRLRIEAAVAAGAKNVVKLLGGQRIQDRKALAEAQAQLQE
                     SSQKLDLLRLALELLLERLPPTHSLRSRVTRELRMAMLGNPQPLGTLVKPIALTGTLQ
                     VRLLGCKELLATVPGRSPMAVLAASPSEGWLRTRSRQQRGGGELASEVLAVLKVDNRV
                     VGQTGWGLVAEKSWDQAFSISLDRARELEIGVHWRDWRQLCGVAFLKLEEFLDNACHQ
                     LSLSLVPQGRLFAQVTFCEPVIERRPRLQRQRRVFSKRRGQDFLRASQMNLSMTAWGR
                     LVMSLLPPCSSPSTVSPPKGCPSAAACETSSSASPSNFRPVKTLPGEDMKPPPKPPRL
                     YLQEPAPGTPCTKRPHMDPRTGVAPPLAALSTRNPPQLQDFRCLAVLGRGHFGKVLLV
                     QYKGTGKYYAIKALKKQEVLGRDEIDSLYCEKRILETVGRTGHPFLLSLLACIQTSSH
                     ACFVTEFLPGGDLMMQIHEDVFPEPQACFYLACVVLGLQFLHEKRIIYRDLKLDNLLL
                     DAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFLAPEVLTQEAYTRAVDWWGLGVLLY
                     EMLVGECPFPGDTEDEVFECIVNADVPCPHFLSAQGLELIQKLLQKSPEKRLGAGERD
                     AEEIKVQPFFRTTNWQALLARTVQPPFVPTLCGPADLRYFEGEFTSLPPTLTPPVPRR
                     SLSARQQAAFRDFDFVSKRFLES"
     exon            393..624
                     /gene="Pkn3"
                     /gene_synonym="LRRGT00147"
                     /inference="alignment:Splign:2.1.0"
     exon            625..770
                     /gene="Pkn3"
                     /gene_synonym="LRRGT00147"
                     /inference="alignment:Splign:2.1.0"
     exon            771..882
                     /gene="Pkn3"
                     /gene_synonym="LRRGT00147"
                     /inference="alignment:Splign:2.1.0"
     exon            883..1010
                     /gene="Pkn3"
                     /gene_synonym="LRRGT00147"
                     /inference="alignment:Splign:2.1.0"
     exon            1011..1194
                     /gene="Pkn3"
                     /gene_synonym="LRRGT00147"
                     /inference="alignment:Splign:2.1.0"
     exon            1195..1341
                     /gene="Pkn3"
                     /gene_synonym="LRRGT00147"
                     /inference="alignment:Splign:2.1.0"
     exon            1342..1451
                     /gene="Pkn3"
                     /gene_synonym="LRRGT00147"
                     /inference="alignment:Splign:2.1.0"
     exon            1452..1595
                     /gene="Pkn3"
                     /gene_synonym="LRRGT00147"
                     /inference="alignment:Splign:2.1.0"
     exon            1596..1671
                     /gene="Pkn3"
                     /gene_synonym="LRRGT00147"
                     /inference="alignment:Splign:2.1.0"
     exon            1672..1834
                     /gene="Pkn3"
                     /gene_synonym="LRRGT00147"
                     /inference="alignment:Splign:2.1.0"
     exon            1835..1931
                     /gene="Pkn3"
                     /gene_synonym="LRRGT00147"
                     /inference="alignment:Splign:2.1.0"
     exon            1932..1999
                     /gene="Pkn3"
                     /gene_synonym="LRRGT00147"
                     /inference="alignment:Splign:2.1.0"
     exon            2000..2063
                     /gene="Pkn3"
                     /gene_synonym="LRRGT00147"
                     /inference="alignment:Splign:2.1.0"
     exon            2064..2155
                     /gene="Pkn3"
                     /gene_synonym="LRRGT00147"
                     /inference="alignment:Splign:2.1.0"
     exon            2156..2332
                     /gene="Pkn3"
                     /gene_synonym="LRRGT00147"
                     /inference="alignment:Splign:2.1.0"
     exon            2333..2395
                     /gene="Pkn3"
                     /gene_synonym="LRRGT00147"
                     /inference="alignment:Splign:2.1.0"
     exon            2396..2472
                     /gene="Pkn3"
                     /gene_synonym="LRRGT00147"
                     /inference="alignment:Splign:2.1.0"
     exon            2473..2615
                     /gene="Pkn3"
                     /gene_synonym="LRRGT00147"
                     /inference="alignment:Splign:2.1.0"
     exon            2616..2723
                     /gene="Pkn3"
                     /gene_synonym="LRRGT00147"
                     /inference="alignment:Splign:2.1.0"
     exon            2724..2804
                     /gene="Pkn3"
                     /gene_synonym="LRRGT00147"
                     /inference="alignment:Splign:2.1.0"
     exon            2805..3290
                     /gene="Pkn3"
                     /gene_synonym="LRRGT00147"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtaaagtgcg gtagattgga gcacctcagt ggtttaggcc gcctgtgaga ctggatctca
       61 ccccctccca gtacccttcc tccggagatc cctcttggcc tgtctagctt atacacattt
      121 tccgatttcc tgtgagcctc cgccctgcag cagcggcagc gaggtgactc aggaccccgg
      181 tggccagcag gcccccagct ctgtgagagc tttgtttgct ctggccttct ggcttggggc
      241 ggccaaagga tttcctgagc ctcgcccttg ccctctgaca gctaaggcag gaccagccaa
      301 cctagctgag gcctggggct gggggattgg ggggccccta aactgagtag ccattcttct
      361 ttcatgggtc ttaggagatg gaacacagaa agcctaggac tggccagaga gcccccgagg
      421 atgagaaaga gatgatccgt cgagctatcc agaaggagtt gaagatcaag gagggcatgg
      481 agaacatgcg tcgtgtggcc acagaccgac gccacctggg ccatgtgcag cagctgctcc
      541 gggcctccaa ccgccgcctg gagcagctgc acggcgagct tcgggagctg catgcccaag
      601 ttttgctgcc agccccagcc cacgagccaa tgacctcagg accccagcca cgggcagagc
      661 agtcgagggc tcggctcctg gaggccttac ataggcagct ggaggtagag ctgaaggtga
      721 aacagggggc tgagaacatg attcacacgt gtgccagcgg cacccccaag gagaggaagc
      781 tcctggcggc tgcccagcag atgttaaagg acagtcagct gaaggtggcc ctactccgaa
      841 tgaagataag cggtctggag gccagtgggt ctccagagcc aggccctgac ttgctggcag
      901 aggagttgca gcaccgactg cgaatagagg ctgctgtggc tgcaggtgcc aagaatgtgg
      961 tgaagctgct tggtggccag agaattcagg accgcaaggc actggccgag gctcaggccc
     1021 agctccagga atcctcccag aagctggacc tcctacggct ggccctggaa ttgttactgg
     1081 agaggttgcc tcccacccac tctcttcgca gcagggtgac ccgagaactg cggatggcca
     1141 tgcttgggaa cccccagcct ctggggacac ttgtgaaacc cattgccctg acagggacac
     1201 tgcaggttcg cctcctgggc tgcaaagaac tgctggcaac cgtgcccgga cggtctccca
     1261 tggctgtcct ggcagctagc ccttctgagg gctggctccg aaccaggtcc aggcagcagc
     1321 gtggtggagg cgaactggcc agtgaagtac tggctgtgtt gaaggttgac aatcgtgttg
     1381 tgggccagac aggatgggga ctggtggctg agaaatcctg ggaccaggct tttagcatct
     1441 ccttggaccg agctcgtgag ctggagatcg gggttcactg gcgggactgg cgacagttgt
     1501 gtggtgtggc attcctgaag cttgaggaat tccttgacaa tgcctgtcac cagctttctc
     1561 tcagtctggt gccgcaggga cggctctttg cccaggtgac cttctgtgag cctgtcattg
     1621 aaaggaggcc gcggctgcag agacagagac gcgttttctc taagcggaga ggccaggatt
     1681 tcctgagagc ttcccagatg aacctcagca tgacggcctg ggggcgcctg gtcatgagct
     1741 tgctaccccc ctgcagctcc ccgagcacag tcagtccccc taaagggtgc ccttcggcgg
     1801 cagcctgtga gacctccagt tctgcttctc ccagtaactt ccggcccgtg aagactctcc
     1861 caggagaaga catgaaacct ccacccaagc ccccacgcct ctatctgcag gaaccagccc
     1921 ccgggactcc ttgtaccaag cgcccccaca tggaccctag aactggagta gcgccccctc
     1981 tggcagcctt gtccaccagg aacccccccc aacttcagga cttccgatgt ttggctgtgc
     2041 tgggccgggg acactttggg aaggtcctcc tggtccagta caaaggaacg ggaaaatact
     2101 acgctatcaa ggcactcaag aaacaggaag tgctaggccg ggatgagatt gacagcctgt
     2161 actgtgagaa gcggatcctg gagactgtgg gtcgtacagg gcacccgttc ttgctctctc
     2221 tccttgcctg catccagacc tccagtcacg cctgctttgt tactgagttt ctgcccggag
     2281 gagacctcat gatgcagatc cacgaggatg tctttcctga gccccaggcc tgcttctacc
     2341 tggcctgtgt ggtcctgggg ctgcagttcc tacacgagaa gaggatcatt tacagggatc
     2401 tgaaattgga taatctacta ctggatgccc agggcttcct caagattgca gacttcggac
     2461 tatgcaaaga aggaattggc tttggtgacc ggaccagcac tttctgtggt accccagagt
     2521 tcctggctcc tgaggttttg actcaggagg cttacactcg ggctgtggac tggtgggggc
     2581 tcggtgtgct gctctatgag atgttagtgg gtgagtgtcc gttcccaggg gacacggaag
     2641 acgaggtgtt tgaatgcatc gtcaatgctg atgtcccatg tccccacttc ctgtcagctc
     2701 aaggcctcga gctcattcag aagctcctcc agaagtcccc agagaagcgt ctaggggcag
     2761 gagagcggga cgccgaggag atcaaggttc agccattctt caggaccacc aactggcagg
     2821 ccttgcttgc ccgcactgtc cagcccccct tcgtgcctac cctctgtggc cctgcagacc
     2881 ttcgttactt cgagggagag ttcaccagcc tgcctccaac cctgacccca ccagtccccc
     2941 gccgttccct ctctgctcgc caacaagctg ccttccggga ctttgacttt gtgtctaagc
     3001 ggttcctgga gtcctgaggg tctcctggca cctctgccag agtgtaggaa gcctccactt
     3061 atccatgtgc ctgggccaaa ggatttaatg agtgtgagat tctaggtagt ggccatgggg
     3121 ctgccgttcg aggcttttct cggtgttgct gctataaccc ctctccttat tcttctgctt
     3181 cctggtagac cccagaccag gaaagacccc acagcagcat ggttggtttc tctttttaat
     3241 acttgacttc atatagagta ttaaattaat aaaactgtac actcgaggta
//
