LOCUS       NM_001105766            1964 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus protein kinase, membrane associated
            tyrosine/threonine 1 (Pkmyt1), mRNA.
ACCESSION   NM_001105766 XM_001053776 XM_213222
VERSION     NM_001105766.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1964)
  AUTHORS   Oh JS, Han SJ and Conti M.
  TITLE     Wee1B, Myt1, and Cdc25 function in distinct compartments of the
            mouse oocyte to control meiotic resumption
  JOURNAL   J Cell Biol 188 (2), 199-207 (2010)
   PUBMED   20083600
REFERENCE   2  (bases 1 to 1964)
  AUTHORS   Ghosh D, Lippert D, Krokhin O, Cortens JP and Wilkins JA.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   3  (bases 1 to 1964)
  AUTHORS   Hendrickx A, Beullens M, Ceulemans H, Den Abt T, Van Eynde A,
            Nicolaescu E, Lesage B and Bollen M.
  TITLE     Docking motif-guided mapping of the interactome of protein
            phosphatase-1
  JOURNAL   Chem Biol 16 (4), 365-371 (2009)
   PUBMED   19389623
REFERENCE   4  (bases 1 to 1964)
  AUTHORS   Booher RN, Holman PS and Fattaey A.
  TITLE     Human Myt1 is a cell cycle-regulated kinase that inhibits Cdc2 but
            not Cdk2 activity
  JOURNAL   J Biol Chem 272 (35), 22300-22306 (1997)
   PUBMED   9268380
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473948.1.
            
            On or before Oct 3, 2007 this sequence version replaced
            XM_001053776.1, XM_213222.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1964
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q12"
     gene            1..1964
                     /gene="Pkmyt1"
                     /gene_synonym="RGD1305434"
                     /note="protein kinase, membrane associated
                     tyrosine/threonine 1"
                     /db_xref="GeneID:287101"
                     /db_xref="RGD:1305434"
     exon            1..221
                     /gene="Pkmyt1"
                     /gene_synonym="RGD1305434"
                     /inference="alignment:Splign:2.1.0"
     exon            222..704
                     /gene="Pkmyt1"
                     /gene_synonym="RGD1305434"
                     /inference="alignment:Splign:2.1.0"
     CDS             354..1826
                     /gene="Pkmyt1"
                     /gene_synonym="RGD1305434"
                     /EC_number="2.7.11.1"
                     /codon_start=1
                     /product="membrane-associated tyrosine- and
                     threonine-specific cdc2-inhibitory kinase"
                     /protein_id="NP_001099236.1"
                     /db_xref="GeneID:287101"
                     /db_xref="RGD:1305434"
                     /translation="MSMPTEGTPPPLSGTPIPVPAYFRHAEPGFSLKRPGGLSRSLPP
                     RPPAKGSIPVSRLFPPRTPGWQQPQPRRVSFLCETSETLQSPGYDPSRPESFFQQNFQ
                     RLSRLGHGSYGEVFKVRSKEDGRLYAVKRSMSPFRGPKDRTRKLAEVGGHEKVGQHPH
                     CVRLERAWEEGGILYLQTELCGPSLQQHCEAWGASLPEAQVWGYLRDTLLALDHLHSQ
                     GLVHLDVKPANIFLGPRGRCKLGDFGLLVELGSAGAGEAQEGDPRYMAPELLRGSYGT
                     AADVFSLGLTILEVACNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVLTMMLEPD
                     PQLRATAEVLLALPMLRQPRPWNVLWYMAAEALSRGWALWQALVTLLCWLWHGLVHPA
                     SWLQPPGPPATPPGSPPCSPLLDSTLSSNWDDDSIGPSLSPETILSRITRRTSTPRGR
                     YTPRDVLDLTDMDSEPPRGPCPTFEPRNLLSLFEDSLDPA"
     exon            705..1198
                     /gene="Pkmyt1"
                     /gene_synonym="RGD1305434"
                     /inference="alignment:Splign:2.1.0"
     exon            1199..1305
                     /gene="Pkmyt1"
                     /gene_synonym="RGD1305434"
                     /inference="alignment:Splign:2.1.0"
     exon            1306..1478
                     /gene="Pkmyt1"
                     /gene_synonym="RGD1305434"
                     /inference="alignment:Splign:2.1.0"
     exon            1479..1636
                     /gene="Pkmyt1"
                     /gene_synonym="RGD1305434"
                     /inference="alignment:Splign:2.1.0"
     exon            1637..1714
                     /gene="Pkmyt1"
                     /gene_synonym="RGD1305434"
                     /inference="alignment:Splign:2.1.0"
     exon            1715..1964
                     /gene="Pkmyt1"
                     /gene_synonym="RGD1305434"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggcggggcc tcgaggccgg tttggaattt ttggcgcgag ctggctccgc gcgcgttcac
       61 gggccgttcc ccttcttgga gggtgcttcg tcctggtgtc caaaggcccc gctgcccgat
      121 cccggcctgc ctggcttctg cgaggtcccc agcggcctcc gccgacccgg aacctgggac
      181 ctcgctgctg cgccgcgctg cgccccgccc agcctcccca ggtacttgtg tcctatacaa
      241 ccttcatgcg gacaatagaa cttgtgtgta gcaaagaagt ggctctcttg tgggccacag
      301 gatccagctc tgtctgaggg gacaccttgt gctctgaccc tctagcactg accatgtcca
      361 tgcccactga gggcacccca ccacccctaa gtggtacccc catcccagtt ccagcttact
      421 tccgacatgc agaacctggt ttctccctca aaaggcctgg gggcctcagc cggagccttc
      481 cacctcggcc ccctgccaag ggcagcatcc ctgtcagccg tctattcccc cctcggaccc
      541 ccggctggca gcagccccag ccccggaggg tgtctttcct gtgcgagacc tcagagacgt
      601 tgcagagccc tgggtacgac ccgagccggc cagagtcctt ctttcagcag aatttccaga
      661 ggctcagccg actgggtcat ggctcctatg gagaagtctt caaggtgcgc tccaaggaag
      721 atgggcgact ctatgctgtt aagcgctcca tgtcaccatt ccgaggcccc aaagatcgga
      781 ctcgtaaact ggctgaggta ggcggccacg agaaggtggg gcagcaccca cattgcgtga
      841 gactggagcg ggcctgggag gagggtggca tcctatacct gcagacagag ctctgtgggc
      901 ccagcctgca gcaacactgt gaagcctggg gggccagcct gccagaggcc caggtctggg
      961 gctacttgcg ggacactctt ctggctctgg accatctaca cagtcaaggc ctagttcacc
     1021 tggatgttaa gcctgccaac atcttcttgg gcccccgggg ccgctgcaag ctgggcgact
     1081 ttggactact ggtggagctc ggttcagccg gtgctggcga ggcccaggag ggagatcctc
     1141 gctacatggc tccagaactg ctgcggggct cctatgggac agctgcagat gtgttcagtc
     1201 tgggtctcac catcttggaa gtggcctgca atatggaact gccccacggt ggggagggat
     1261 ggcagcagct gcgccaggga tacttgccgc ccgagttcac tgctggtctg tcttctgagc
     1321 tgcgttctgt cctcaccatg atgttggagc ctgaccccca gcttcgagcc acggctgagg
     1381 tcctgctggc cttgcccatg ctgaggcagc cacgtccctg gaatgttctg tggtatatgg
     1441 ctgcagaagc cctgagtcga ggttgggccc tgtggcaggc tctggtcact ctgctctgct
     1501 ggctctggca tggcctggtt catcctgcca gttggctgca gcctccaggc ccaccagcca
     1561 caccacctgg ctctccacca tgcagtcccc tcctggacag caccctctcc agcaactggg
     1621 atgatgacag cataggcccc tcactttccc cagagaccat cctgtcccgg atcacgagga
     1681 gaacctctac ccctcggggc aggtacacac caagggatgt cctggaccta actgatatgg
     1741 actcagagcc tccaagaggt ccctgcccca cctttgagcc aaggaatctc ctcagcctgt
     1801 ttgaggactc cctagaccca gcctgagcca caggcccagt cagccttggt gcttttaaac
     1861 ctctgaactt cttgcccacc tctccccctg aaacttctgt atctaataaa aagtaatgag
     1921 tcttgggaac acccaaggtt gctcatatgg caacagagtg cttc
//
