LOCUS       NM_001401797            1085 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus cAMP-dependent protein kinase inhibitor gamma
            (Pkig), transcript variant 6, mRNA.
ACCESSION   NM_001401797 XM_008762469
VERSION     NM_001401797.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1085)
  AUTHORS   Chen,X., Dai,J.C., Orellana,S.A. and Greenfield,E.M.
  TITLE     Endogenous protein kinase inhibitor gamma terminates
            immediate-early gene expression induced by cAMP-dependent protein
            kinase (PKA) signaling: termination depends on PKA inactivation
            rather than PKA export from the nucleus
  JOURNAL   J Biol Chem 280 (4), 2700-2707 (2005)
   PUBMED   15557275
  REMARK    GeneRIF: endogenous levels of PKI regulate PKA signaling
REFERENCE   2  (bases 1 to 1085)
  AUTHORS   Collins,S.P. and Uhler,M.D.
  TITLE     Characterization of PKIgamma, a novel isoform of the protein kinase
            inhibitor of cAMP-dependent protein kinase
  JOURNAL   J Biol Chem 272 (29), 18169-18178 (1997)
   PUBMED   9218452
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Feb 25, 2022 this sequence version replaced XM_008762469.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DV214438.1, SRR21887620.2000681.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760386, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-108               JAXUCZ010000003.1  172786275-172786382
            109-177             JAXUCZ010000003.1  172795257-172795325
            178-351             JAXUCZ010000003.1  172812456-172812629
            352-1085            JAXUCZ010000003.1  172816781-172817514
FEATURES             Location/Qualifiers
     source          1..1085
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q42"
     gene            1..1085
                     /gene="Pkig"
                     /note="cAMP-dependent protein kinase inhibitor gamma"
                     /db_xref="GeneID:266709"
                     /db_xref="RGD:628775"
     exon            1..108
                     /gene="Pkig"
                     /inference="alignment:Splign:2.1.0"
     exon            109..177
                     /gene="Pkig"
                     /inference="alignment:Splign:2.1.0"
     exon            178..351
                     /gene="Pkig"
                     /inference="alignment:Splign:2.1.0"
     CDS             201..431
                     /gene="Pkig"
                     /note="protein kinase inhibitor, gamma; protein kinase
                     (cAMP-dependent, catalytic) inhibitor gamma"
                     /codon_start=1
                     /product="cAMP-dependent protein kinase inhibitor gamma"
                     /protein_id="NP_001388726.1"
                     /db_xref="GeneID:266709"
                     /db_xref="RGD:628775"
                     /translation="MMEVESSYSDFISCDRTGRRNAVPDIQGDSEAVSVRKLAGDMGE
                     LALEGAEGQAEGSTPDKEASSQPESSDANTSS"
     exon            352..1085
                     /gene="Pkig"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aggagcgagc tgtctgcccc acctgccctg cccttctgag ctctggcttc ttgttctacc
       61 tacctatcct tctgacctgg gacctctgtg cttggagacc tggctcctat ttctacactg
      121 gttaatcagg agtgaaaact ctgaagagat gcaagcagga agacgaaatt aaactaggcc
      181 tgaggagcga tgcgacaggc atgatggaag tcgagtcctc ctactcggac ttcatctcct
      241 gtgaccggac aggccgtcgg aatgcagtcc ctgacatcca gggtgactcg gaggccgtga
      301 gcgtgcggaa gctagctgga gacatgggcg agctcgcact tgagggggca gaaggacagg
      361 cagagggaag taccccagac aaggaagcca gcagccagcc ggagagcagt gacgcgaaca
      421 cctcatcctg agtctgcctg tggtcctcac aggctgagag agacctgctg tccctcctgc
      481 actggagccc tggccagcca ggctgactga gagcctcatg gagtcctctg tggcccctgc
      541 tccagtaaag tcctccactc acaccacagg ctcctctttc ccacctccca cggtgcccac
      601 ggtgcccagg gtgcccaggc gcacttcaga gacacgagca ccatgaggtg ttatctcttc
      661 agctgggcgg ggctcgagcc aggccctgcc cctaggtgag cggctgtcac ctggacaggg
      721 atgtccggcc accactcacc cctccagcca gccccctcta gccagccatc cgttgagaag
      781 atcttcctag ccctttttta aagcctcttt tacatttttt aaaaacataa ctttttcaga
      841 gagagagagg ggagcggaca atcacttttt ttctgttttg gtttttggtt ggtttttttt
      901 ctttttttga aagacatttt aagctcagtt ctgatgatct atgcagctct aagttccctc
      961 acagagcctc acagatccag ttttgggaaa ggatttggac tcaaaactaa ctgaccaatt
     1021 ctttgccctt tgtaccaaga gactgatact tagacctagg aaataaatgc tggtgatttg
     1081 tgtga
//
