LOCUS       NM_001108007            1855 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus protein kinase domain containing, cytoplasmic
            (Pkdcc), mRNA.
ACCESSION   NM_001108007 XM_001061539 XM_233838
VERSION     NM_001108007.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1855)
  AUTHORS   Bordoli MR, Yum J, Breitkopf SB, Thon JN, Italiano JE Jr, Xiao J,
            Worby C, Wong SK, Lin G, Edenius M, Keller TL, Asara JM, Dixon JE,
            Yeo CY and Whitman M.
  TITLE     A secreted tyrosine kinase acts in the extracellular environment
  JOURNAL   Cell 158 (5), 1033-1044 (2014)
   PUBMED   25171405
  REMARK    Erratum:[Cell. 2014 Nov 6;159(4):955]
REFERENCE   2  (bases 1 to 1855)
  AUTHORS   Goncalves L, Filipe M, Marques S, Salgueiro AM, Becker JD and Belo
            JA.
  TITLE     Identification and functional analysis of novel genes expressed in
            the Anterior Visceral Endoderm
  JOURNAL   Int J Dev Biol 55 (3), 281-295 (2011)
   PUBMED   21553379
REFERENCE   3  (bases 1 to 1855)
  AUTHORS   Kinoshita M, Era T, Jakt LM and Nishikawa S.
  TITLE     The novel protein kinase Vlk is essential for stromal function of
            mesenchymal cells
  JOURNAL   Development 136 (12), 2069-2079 (2009)
   PUBMED   19465597
REFERENCE   4  (bases 1 to 1855)
  AUTHORS   Imuta Y, Nishioka N, Kiyonari H and Sasaki H.
  TITLE     Short limbs, cleft palate, and delayed formation of flat
            proliferative chondrocytes in mice with targeted disruption of a
            putative protein kinase gene, Pkdcc (AW548124)
  JOURNAL   Dev Dyn 238 (1), 210-222 (2009)
   PUBMED   19097194
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473947.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001061539.1, XM_233838.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC166535.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760494 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1855
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q12"
     gene            1..1855
                     /gene="Pkdcc"
                     /gene_synonym="RGD1311939; Sgk493"
                     /note="protein kinase domain containing, cytoplasmic"
                     /db_xref="GeneID:313860"
                     /db_xref="RGD:1311939"
     exon            1..248
                     /gene="Pkdcc"
                     /gene_synonym="RGD1311939; Sgk493"
                     /inference="alignment:Splign:2.1.0"
     CDS             207..1088
                     /gene="Pkdcc"
                     /gene_synonym="RGD1311939; Sgk493"
                     /EC_number="2.7.10.2"
                     /note="sugen kinase 493; protein kinase domain-containing
                     protein, cytoplasmic; protein kinase-like protein SgK493"
                     /codon_start=1
                     /product="extracellular tyrosine-protein kinase PKDCC"
                     /protein_id="NP_001101477.1"
                     /db_xref="GeneID:313860"
                     /db_xref="RGD:1311939"
                     /translation="MVLLERLRHPNVLQLYGYCYQDSEDIPDTLTTITELGAPVEMIQ
                     LLQTSWEDRFRICLSLGRLLHYLAHSPLGSVTLLDFRPRQFVLVDGELKVTDLDDARV
                     EETPCTNGADCVLEFPARNFSLPCSAQGWCEGMNEKRNLYNAYRFFFTYLLPHSAPPS
                     LRPLLDTIVNATGELAWGADETLAQLEMVLHLFRSGQYLQNSTSSRAEYQRIPDSTIT
                     QEDYRCWPSYHHGGCLLSVFNLAEAVDVCESHVQCRAFVVTNQTTWTGRKLVFFKTGW
                     NQVVPDASKTTFVKAPG"
     exon            249..371
                     /gene="Pkdcc"
                     /gene_synonym="RGD1311939; Sgk493"
                     /inference="alignment:Splign:2.1.0"
     exon            372..643
                     /gene="Pkdcc"
                     /gene_synonym="RGD1311939; Sgk493"
                     /inference="alignment:Splign:2.1.0"
     exon            644..723
                     /gene="Pkdcc"
                     /gene_synonym="RGD1311939; Sgk493"
                     /inference="alignment:Splign:2.1.0"
     exon            724..828
                     /gene="Pkdcc"
                     /gene_synonym="RGD1311939; Sgk493"
                     /inference="alignment:Splign:2.1.0"
     exon            829..1002
                     /gene="Pkdcc"
                     /gene_synonym="RGD1311939; Sgk493"
                     /inference="alignment:Splign:2.1.0"
     exon            1003..1855
                     /gene="Pkdcc"
                     /gene_synonym="RGD1311939; Sgk493"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctgcgccgc gctccgcaac gtgtctggcg cgcagtacgt gggctctggc tacactaagg
       61 ctgtgtaccg ggtccgcctg cccggcggcg ccgcggtggc gcttaaagca gtggacttca
      121 gcggccacga tctgggcagc tgtgtgcgcg agttcggggc gcgaaggggc tgctaccgcc
      181 tggcggccca caagctgctc aaggagatgg tgctgctgga gcggctgcgg caccccaacg
      241 tgctgcagct ctatggctat tgctaccagg acagtgagga catcccggac acactgacca
      301 ccatcacaga gctgggcgct cctgtggaga tgatccagct gttgcagact tcctgggagg
      361 atcgattccg aatctgcctc agccttggcc gcctcctcca ctacctagcc cactcccctc
      421 taggctcggt cactctgctt gacttccgcc ctcggcagtt tgtgcttgtg gatggggagc
      481 tgaaggtgac ggacctggac gacgcccgag tggaggagac accgtgcact aacggtgccg
      541 actgcgtgct agagtttcca gccaggaact tcagcctgcc ctgctcggcc cagggctggt
      601 gcgagggcat gaacgagaaa cggaacctct acaatgccta caggttcttc ttcacatacc
      661 tcctgccaca tagtgccccg ccttccctcc gacctctcct ggacaccatc gtcaatgcta
      721 caggagagct cgcctggggg gcggatgaga ccctggccca gctggagatg gtgctgcacc
      781 tgttccggag tgggcagtac ctgcagaact ctacaagcag cagggctgag taccagcgca
      841 tcccggacag taccatcaca caggaggatt atcgctgctg gccctcctac caccatggtg
      901 gctgcctcct gtctgtgttc aacctggctg aggctgtaga tgtctgtgag agccatgttc
      961 aatgtcgtgc ctttgtggtc accaaccaga ccacctggac aggtcggaag ctggtctttt
     1021 ttaagactgg atggaaccaa gtggtccctg atgccagcaa gaccacgttt gtgaaggccc
     1081 ctggttgacg ggttgcgggc ctcgctgacc agctgggttt gcctgctgca ggcgtgactt
     1141 gcatagcacc cgggaaccct gcagacagag ctagcgtccc agagcaactg atgtgaccag
     1201 gacaaacgtg caatatgcaa aagtgttaaa atgtgagttt gccagctttc ggtctaagac
     1261 tgttgctccc agcctgagcg tcactggttg ggatctgatt gcctctctgg agctgtgagc
     1321 agggctcagg ctggtcttaa ctgggatagt cccatgggca gccccattac tgcattcaca
     1381 gtttgagaat gtagccagac actgctgctg ctgctgctgc ataagccaca gtgggcagga
     1441 gctgcacggg gacagtcagt cgcagagtgt tctctcagct cagctccaaa tggatcgccg
     1501 ggggaatgct ccaagatgtg agggagccag ccgtgggaag gctctctggc ctctccctac
     1561 gggttgctcc tcagccagcc ccaggtcatg ggcagcagtg cacacatcca tatgagccaa
     1621 gactagagtg gaggagcaga ttgcatttga gccaggacct ggggtggggg tagggtcggg
     1681 gcctttctgc ctcatttgct ttcagtgaaa gccaccaagc agccgaaacc aggctctccc
     1741 cctcctggag tgtgcatatc cagaagcttt tgtacttctt gttcatgaaa ttgtttattt
     1801 ttgtaaaaaa aaaattaatc aattaataaa atgatgtttt gtgacaaata ctccc
//
