LOCUS       NP_001100609            1281 aa            linear   ROD 24-JUN-2024
DEFINITION  membrane-associated phosphatidylinositol transfer protein 2 [Rattus
            norvegicus].
ACCESSION   NP_001100609 XP_001079124 XP_222155
VERSION     NP_001100609.1
DBSOURCE    REFSEQ: accession NM_001107139.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 1281)
  AUTHORS   Lu,C., Vihtelic,T.S., Hyde,D.R. and Li,T.
  TITLE     A neuronal-specific mammalian homolog of the Drosophila retinal
            degeneration B gene with expression restricted to the retina and
            dentate gyrus
  JOURNAL   J Neurosci 19 (17), 7317-7325 (1999)
   PUBMED   10460238
REFERENCE   2  (residues 1 to 1281)
  AUTHORS   Lev,S., Hernandez,J., Martinez,R., Chen,A., Plowman,G. and
            Schlessinger,J.
  TITLE     Identification of a novel family of targets of PYK2 related to
            Drosophila retinal degeneration B (rdgB) protein
  JOURNAL   Mol Cell Biol 19 (3), 2278-2288 (1999)
   PUBMED   10022914
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473973.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XP_222155.4, XP_001079124.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132268,
                              SAMD00132284 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1281
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q15"
     Protein         1..1281
                     /product="membrane-associated phosphatidylinositol
                     transfer protein 2"
                     /calculated_mol_wt=142448
     Region          1..258
                     /region_name="SRPBCC_PITPNM1-2_like"
                     /note="Lipid-binding SRPBCC domain of mammalian PITPNM1-2
                     and related proteins (Class IIA PITPs); cd08889"
                     /db_xref="CDD:176898"
     Site            order(21..22,25,29,32,40,59,61,63,65,68,70,73,77,81..82,
                     84,86,88,90,95,97,99,102..103,109,111,192,198,200,210,
                     218..220,223)
                     /site_type="other"
                     /note="putative lipid binding site [chemical binding]"
                     /db_xref="CDD:176898"
     Site            65..83
                     /site_type="active"
                     /note="putative lipid exchange loop [active]"
                     /db_xref="CDD:176898"
     Site            order(118..147,153..177,186..187)
                     /site_type="active"
                     /note="putatative regulatory loop [active]"
                     /db_xref="CDD:176898"
     Site            164
                     /site_type="other"
                     /note="putative PKC phosphorylation site
                     [posttranslational modification]"
                     /db_xref="CDD:176898"
     Region          701..894
                     /region_name="DDHD"
                     /note="DDHD domain; pfam02862"
                     /db_xref="CDD:460725"
     Region          1040..1171
                     /region_name="LNS2"
                     /note="This domain is found in Saccharomyces cerevisiae
                     protein SMP2, proteins with an N-terminal lipin domain and
                     phosphatidylinositol transfer proteins; smart00775"
                     /db_xref="CDD:197870"
     CDS             1..1281
                     /gene="Pitpnm2"
                     /coded_by="NM_001107139.1:202..4047"
                     /db_xref="GeneID:304474"
                     /db_xref="RGD:1310867"
ORIGIN      
        1 miikeyripl pmtveeyria qlymiqkksr netygqgsgv eilenrpytd gpggsgqyth
       61 kvyhvgmhip gwfrsilpka alrvveeswn aypytrtrft cpfvekfsid ietfyktdtg
      121 ennnvfnlsp veknqlitdi idivkdpvtp seykteedpk lfqsiktrrg plsenwiqey
      181 kkrllpimca yklckvefry wgmqskierf ihdtglrrvm vrahrqawcw qdewygltme
      241 kirelekevq lmlsrkmaqf seegpselsk estikdqatg atpepsssng eslgrglkkq
      301 wstsskssrs skrgaspsrh sisewrmqsi ardsdessee effdaqenlq hkeemytkdi
      361 tkwssndlmd kmenpepees qdslyhqsgs efrvassveq lntiedevsq platppskih
      421 vlllvlhggt ildtgagdps skqgdtntit nvfdtvmrvh ypsalghlai rlvpcppica
      481 dafalvsnls pyghdegcls ssqdhiplaa lpllatsspq yqeavatviq ranlaygdfi
      541 ksqegvtfng qvcligdcvg gilafdalcy sgqpvsesqs ssrrgsvvsm qdadllspgi
      601 lvnaahcsgg sgggsgggss lessrhlsrs nidiprsngt edsrkqmprk rsdsstyeld
      661 tiqqhqafls slhasvlrne pssrrsssst mldgagalgk fdfeiadlfl fgcplglvla
      721 lrktvipsld vfqlrpacqq vynlfhpadp sasrleplle rrfhtlppfn ipryqryplg
      781 dgcstllada lqthntvfqe haapsspgta pasrgfrras eisiasqvsg maesytasgi
      841 aqiaakwwgq kridyalycp dalmafptva lphlfhasyw estdvvsfll rqvmrhdsas
      901 ileldgkevs vftpsqprek wqrkrthvkl rnvaanhrin davanedgpq vvtgrfmygp
      961 ldmvtltgek vdvhimtqpp sgewlyldtl vtnssgrvsy tipethrlgv gvypikmvvr
     1021 gdhtfadsyi tvlpkgtefv vfsidgsfaa svsimgsdpk vragavdvvr hwqdlgylii
     1081 yvtgrpdmqk qrvvawlaqh nfphgvvsfc dglvhdplrh kanflkllis elhlrahaay
     1141 gstkdvavyn sislspmhiy ivgrptkklq qqcqfitdgy aahlaqlkyn hrarparnta
     1201 trmalrkgsf glpgqgdflr srnhllrtis aqpsgpshrh drtqtqmdle qrgqrsmsma
     1261 ascwgramag rlepgaatgp k
//
