LOCUS       NM_001399521            1523 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus PITH domain containing 1 (Pithd1), mRNA.
ACCESSION   NM_001399521 XM_216543
VERSION     NM_001399521.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1523)
  AUTHORS   Lu,B., Sun,X., Chen,Y., Jin,Q., Liang,Q., Liu,S., Li,Y., Zhou,Y.,
            Li,W. and Huang,Z.
  TITLE     Novel function of PITH domain-containing 1 as an activator of
            internal ribosomal entry site to enhance RUNX1 expression and
            promote megakaryocyte differentiation
  JOURNAL   Cell Mol Life Sci 72 (4), 821-832 (2015)
   PUBMED   25134913
REFERENCE   2  (bases 1 to 1523)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Jan 10, 2022 this sequence version replaced XM_216543.9.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR22399492.2003945.1,
                                           SRR22582416.1238806.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840115, SAMN12840129
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-290               JAXUCZ010000005.1  153499736-153500025 c
            291-334             JAXUCZ010000005.1  153499189-153499232 c
            335-412             JAXUCZ010000005.1  153498750-153498827 c
            413-517             JAXUCZ010000005.1  153492079-153492183 c
            518-626             JAXUCZ010000005.1  153491113-153491221 c
            627-1523            JAXUCZ010000005.1  153489529-153490425 c
FEATURES             Location/Qualifiers
     source          1..1523
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..1523
                     /gene="Pithd1"
                     /gene_synonym="RGD1308048"
                     /note="PITH domain containing 1"
                     /db_xref="GeneID:298557"
                     /db_xref="RGD:1308048"
     exon            1..290
                     /gene="Pithd1"
                     /gene_synonym="RGD1308048"
                     /inference="alignment:Splign:2.1.0"
     CDS             93..728
                     /gene="Pithd1"
                     /gene_synonym="RGD1308048"
                     /note="PITH (C-terminal proteasome-interacting domain of
                     thioredoxin-like) domain containing 1"
                     /codon_start=1
                     /product="PITH domain-containing protein 1"
                     /protein_id="NP_001386450.1"
                     /db_xref="GeneID:298557"
                     /db_xref="RGD:1308048"
                     /translation="MSHGHSHGGGGCRCAAEREEPPEQRGLAYGLYLRIDLERLQCLN
                     ESREGSGRGVFKPWEERTDRSKFVESDADEELLFNIPFTGNVKLKGIIIMGEDDDSHP
                     SEMRLYKNIPQMSFDDTEREPDQTFSLNRDITGELEYATKISRFSNVYHLSIHISKNF
                     GADTTKIFYIGLRGEWTELRRHEVTICNYEASANPADHRVHQVTPQTHFIS"
     exon            291..334
                     /gene="Pithd1"
                     /gene_synonym="RGD1308048"
                     /inference="alignment:Splign:2.1.0"
     exon            335..412
                     /gene="Pithd1"
                     /gene_synonym="RGD1308048"
                     /inference="alignment:Splign:2.1.0"
     exon            413..517
                     /gene="Pithd1"
                     /gene_synonym="RGD1308048"
                     /inference="alignment:Splign:2.1.0"
     exon            518..626
                     /gene="Pithd1"
                     /gene_synonym="RGD1308048"
                     /inference="alignment:Splign:2.1.0"
     exon            627..1523
                     /gene="Pithd1"
                     /gene_synonym="RGD1308048"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgcggcgctt ggcggccggc gcggagtcga gtgagctccg ggtgagcggc ggggccgaga
       61 gagtcggggg tgaccctgcg ggccgcgtcg ccatgtcgca cggccacagc cacggcgggg
      121 gcggctgtcg ctgcgccgcc gaacgcgagg agccgccgga gcagcgcggc ctggcctacg
      181 ggctgtacct gcgcatcgac ctggagcgac tgcagtgcct caatgagagc cgcgagggca
      241 gcggccgcgg cgtcttcaag ccgtgggagg agcggaccga ccgctctaag tttgttgaaa
      301 gtgatgcgga tgaagagctt ctgtttaata ttccatttac gggcaatgtc aagctcaaag
      361 gcatcatcat aatgggagaa gacgatgact cacacccttc ggagatgaga ctgtacaaga
      421 acattccaca gatgtcattt gatgatacag aaagggagcc agaccagacc tttagtctga
      481 accgagatat cacaggagaa ttagagtatg ctacaaaaat ttctcggttt tccaatgtct
      541 atcatctttc cattcatatt tcaaaaaact ttggagcgga taccacgaag atcttttata
      601 ttggcctgag gggagagtgg actgagcttc gccggcatga ggtgaccatc tgcaactatg
      661 aagcgtcagc caacccagca gaccaccggg tgcatcaggt caccccacag acacatttca
      721 tttcttaagg gccaccaggg ctccctcaga tgcgcattag tgaagatgtg cggccacctg
      781 ctggggagga cagaggctgc tccagcgaga gttggatttg cctgccgcag ccgtggtccg
      841 gctttgtctt ggggttgcta caggaacctg gcctgtggaa ccgcctcacc accgggagcg
      901 gtgcgggtgc caagggacag cctctctaag gcactgtaga cctgggtctt aggctgggtg
      961 gcatctgaca gtcatgaata atgctcactt tcctagtctg gccatggatc ccaagtatct
     1021 tctcacttgt ggcagatttc ttgtgtggtt tgtccttttt aaaaaaggaa gcttcctcag
     1081 ctgtaggaaa ccttccgaaa cctgagtttt gtgtttgaat tagccatcag gaggatctcc
     1141 aacgagaaac acacgtccct gcttgctgct cctcctgtca ctgcttagca tttgtgtccg
     1201 ggtgcccagc tggtgtcata tcacacacaa gtgtcccatg actggttgga aaggaaggaa
     1261 tctcctgtag gtgacacttg gggaaggcct ttcacactgt ctagccaaat agttgggaga
     1321 acatggagtc ctttctgtgt gggtgacctg tgtggggtaa gattgagacc tggtaaaaat
     1381 tcccctcggg acctccttgg tgtttacttg cttctactcg tgttgtaaac ccagtgctgg
     1441 agtctgaaga ccctgctcct tctgttcatg gctttcattc actgtgtgac taatgagctt
     1501 cctaataaat ccttagagac taa
//
