LOCUS       NM_001313924            2499 bp    mRNA    linear   ROD 09-APR-2024
DEFINITION  Rattus norvegicus paired Ig-like receptor B (Pirb), mRNA.
ACCESSION   NM_001313924 NM_001313948 XM_006223025 XM_006228065 XM_006228071
VERSION     NM_001313924.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2499)
  AUTHORS   Kim,T., Vidal,G.S., Djurisic,M., William,C.M., Birnbaum,M.E.,
            Garcia,K.C., Hyman,B.T. and Shatz,C.J.
  TITLE     Human LilrB2 is a beta-amyloid receptor and its murine homolog PirB
            regulates synaptic plasticity in an Alzheimer's model
  JOURNAL   Science 341 (6152), 1399-1404 (2013)
   PUBMED   24052308
REFERENCE   2  (bases 1 to 2499)
  AUTHORS   Mori,Y., Tsuji,S., Inui,M., Sakamoto,Y., Endo,S., Ito,Y.,
            Fujimura,S., Koga,T., Nakamura,A., Takayanagi,H., Itoi,E. and
            Takai,T.
  TITLE     Inhibitory immunoglobulin-like receptors LILRB and PIR-B negatively
            regulate osteoclast development
  JOURNAL   J Immunol 181 (7), 4742-4751 (2008)
   PUBMED   18802077
REFERENCE   3  (bases 1 to 2499)
  AUTHORS   Cao,W., Rosen,D.B., Ito,T., Bover,L., Bao,M., Watanabe,G., Yao,Z.,
            Zhang,L., Lanier,L.L. and Liu,Y.J.
  TITLE     Plasmacytoid dendritic cell-specific receptor ILT7-Fc epsilonRI
            gamma inhibits Toll-like receptor-induced interferon production
  JOURNAL   J Exp Med 203 (6), 1399-1405 (2006)
   PUBMED   16735691
REFERENCE   4  (bases 1 to 2499)
  AUTHORS   Shultz,M.A., Zhang,L., Gu,Y.Z., Baker,G.L., Fannuchi,M.V.,
            Padua,A.M., Gurske,W.A., Morin,D., Penn,S.G., Jovanovich,S.B.,
            Plopper,C.G. and Buckpitt,A.R.
  TITLE     Gene expression analysis in response to lung toxicants: I.
            Sequencing and microarray development
  JOURNAL   Am J Respir Cell Mol Biol 30 (3), 296-310 (2004)
   PUBMED   12947022
REFERENCE   5  (bases 1 to 2499)
  AUTHORS   Ujike,A., Takeda,K., Nakamura,A., Ebihara,S., Akiyama,K. and
            Takai,T.
  TITLE     Impaired dendritic cell maturation and increased T(H)2 responses in
            PIR-B(-/-) mice
  JOURNAL   Nat Immunol 3 (6), 542-548 (2002)
   PUBMED   12021780
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On or before Feb 14, 2023 this sequence version replaced
            NM_001313948.1, XM_006228065.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643290.819.1, SRR26643284.283.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-168               JAXUCZ010000001.1  74414556-74414723
            169-204             JAXUCZ010000001.1  74414886-74414921
            205-489             JAXUCZ010000001.1  74415100-74415384
            490-795             JAXUCZ010000001.1  74415471-74415776
            796-1080            JAXUCZ010000001.1  74416829-74417113
            1081-1389           JAXUCZ010000001.1  74417240-74417548
            1390-1692           JAXUCZ010000001.1  74418303-74418605
            1693-1743           JAXUCZ010000001.1  74418902-74418952
            1744-1869           JAXUCZ010000001.1  74419901-74420026
            1870-1945           JAXUCZ010000001.1  74420314-74420389
            1946-1983           JAXUCZ010000001.1  74420466-74420503
            1984-2036           JAXUCZ010000001.1  74420735-74420787
            2037-2189           JAXUCZ010000001.1  74421489-74421641
            2190-2499           JAXUCZ010000001.1  74421718-74422027
FEATURES             Location/Qualifiers
     source          1..2499
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q12"
     gene            1..2499
                     /gene="Pirb"
                     /gene_synonym="Lilrb3a; Lilrb3b; Lilrb3l; Pir-A1"
                     /note="paired Ig-like receptor B"
                     /db_xref="GeneID:683463"
                     /db_xref="RGD:1589827"
     exon            1..168
                     /gene="Pirb"
                     /gene_synonym="Lilrb3a; Lilrb3b; Lilrb3l; Pir-A1"
                     /inference="alignment:Splign:2.1.0"
     CDS             135..2369
                     /gene="Pirb"
                     /gene_synonym="Lilrb3a; Lilrb3b; Lilrb3l; Pir-A1"
                     /note="leukocyte immunoglobulin-like receptor subfamily B
                     member 3-like; Leukocyte immunoglobulin-like receptor
                     subfamily B member 3A; Leukocyte immunoglobulin-like
                     receptor subfamily B member 3B; leukocyte
                     immunoglobulin-like receptor, subfamily B (with TM and
                     ITIM domains), member 3B; leukocyte immunoglobulin-like
                     receptor, subfamily B (with TM and ITIM domains), member
                     3A"
                     /codon_start=1
                     /product="leukocyte immunoglobulin-like receptor subfamily
                     B member 3A precursor"
                     /protein_id="NP_001300853.1"
                     /db_xref="GeneID:683463"
                     /db_xref="RGD:1589827"
                     /translation="MTFTFTALLCLGLTLGLWIPVLTGSLPKPILRVQPDSVVSMGTT
                     VTFICEETIGAKQSYLYRNGNLQRRVPKNNQKPTNKTEFLFLNVGHQNAGQYHCSYKS
                     QGKSSDYSEPLELVVTGAYSKPSLSAQTNPVVTSGGYVTLKCEPSHYGHTLILTVEGP
                     QKLSWRQDPQCNYYTENCHVLFYVGPLTSNQRWIFRCYSYETNTPQVWSAPSEPVEIL
                     VSGKLQKPTIKAEPGSVIHSGKAMIIWCQGDLDAEIYFLHKEGSHNTQSTQTLQQPGN
                     KAKLFIRPVTQGHAGDYRCYYYSSAGWSEPSDTLELVVTGIYNYHPLMLSGPPSPVVP
                     EGGNVTLHCTSHRYYDKFILIKEDQKFSSSLDTKYISSTGQHQALFVMGPMTPNYSGT
                     FRCYGYYKHTPQLWSEPSNLLKILITGQLHHVLFLSVMPNSTVHSGENVTLMCWSTYS
                     VDTFILSKEGSGQPPLRLKSKIQDQQYQSEFSMSGVTSKLSGTYRCYGSHDSSLYLLS
                     FASAPVELIVSGPIRTSDLPPTMSIPPDGLQRYLKALIGVSVAFLLFLFILIFILLRR
                     RHQEKFRKDDEDAQKGKELQLSTGAAEPVTRDRGHQKRSNPAAATQEESLYASVEDME
                     TKDGVELDTWKPPEGDPQGETYAQVEPSRLRRAGAISPVVSREQLNTKYEQAEEGQEV
                     DSQATESEEPQDVTYAQLCSRTLRQGTAAPPLSQAGEAPEEPSVYAALATARPGAVPK
                     NKKQ"
     exon            169..204
                     /gene="Pirb"
                     /gene_synonym="Lilrb3a; Lilrb3b; Lilrb3l; Pir-A1"
                     /inference="alignment:Splign:2.1.0"
     exon            205..489
                     /gene="Pirb"
                     /gene_synonym="Lilrb3a; Lilrb3b; Lilrb3l; Pir-A1"
                     /inference="alignment:Splign:2.1.0"
     exon            490..795
                     /gene="Pirb"
                     /gene_synonym="Lilrb3a; Lilrb3b; Lilrb3l; Pir-A1"
                     /inference="alignment:Splign:2.1.0"
     exon            796..1080
                     /gene="Pirb"
                     /gene_synonym="Lilrb3a; Lilrb3b; Lilrb3l; Pir-A1"
                     /inference="alignment:Splign:2.1.0"
     exon            1081..1389
                     /gene="Pirb"
                     /gene_synonym="Lilrb3a; Lilrb3b; Lilrb3l; Pir-A1"
                     /inference="alignment:Splign:2.1.0"
     exon            1390..1692
                     /gene="Pirb"
                     /gene_synonym="Lilrb3a; Lilrb3b; Lilrb3l; Pir-A1"
                     /inference="alignment:Splign:2.1.0"
     exon            1693..1743
                     /gene="Pirb"
                     /gene_synonym="Lilrb3a; Lilrb3b; Lilrb3l; Pir-A1"
                     /inference="alignment:Splign:2.1.0"
     exon            1744..1869
                     /gene="Pirb"
                     /gene_synonym="Lilrb3a; Lilrb3b; Lilrb3l; Pir-A1"
                     /inference="alignment:Splign:2.1.0"
     exon            1870..1945
                     /gene="Pirb"
                     /gene_synonym="Lilrb3a; Lilrb3b; Lilrb3l; Pir-A1"
                     /inference="alignment:Splign:2.1.0"
     exon            1946..1983
                     /gene="Pirb"
                     /gene_synonym="Lilrb3a; Lilrb3b; Lilrb3l; Pir-A1"
                     /inference="alignment:Splign:2.1.0"
     exon            1984..2036
                     /gene="Pirb"
                     /gene_synonym="Lilrb3a; Lilrb3b; Lilrb3l; Pir-A1"
                     /inference="alignment:Splign:2.1.0"
     exon            2037..2189
                     /gene="Pirb"
                     /gene_synonym="Lilrb3a; Lilrb3b; Lilrb3l; Pir-A1"
                     /inference="alignment:Splign:2.1.0"
     exon            2190..2499
                     /gene="Pirb"
                     /gene_synonym="Lilrb3a; Lilrb3b; Lilrb3l; Pir-A1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cctgtagcgc tgctgaaaaa tgaccagtca tggggactgt actgcttcca gggccacacc
       61 ctgtttccaa tcccttcaga aaggctctgt agctctgctc tccagcagag ttgcaacctc
      121 tgagaggaga tgccatgacc ttcaccttta cagccctgct ctgtcttgga ctgactctgg
      181 gcctctggat cccagtgctg acagggtccc tccctaagcc tatcctcaga gtacagccag
      241 attctgtggt ctcaatggga actacggtga ccttcatttg tgaggagacc attggagcca
      301 aacagtctta tctctataga aatggaaacc tacagagaag agttccaaag aacaatcaga
      361 agccaacaaa caagactgaa ttcttatttt taaatgtagg ccatcaaaat gcagggcaat
      421 atcactgttc ctacaagtct cagggtaaat catcagacta cagtgagccc ctggagctag
      481 tggtcacagg agcctactcg aaacccagcc tttcagccca gaccaatcct gtggtgacct
      541 caggagggta tgtcaccctc aaatgtgagc cctcgcatta cggtcacaca ttgattctta
      601 ctgtagaagg acctcagaag ctctcctgga ggcaggaccc acagtgtaac tactatactg
      661 agaattgtca tgtcctgttc tatgtgggtc cattgacctc caaccagagg tggatattca
      721 gatgctacag ctatgaaaca aacacaccac aagtgtggtc agctcctagt gaaccagtgg
      781 agatcctggt gtcagggaaa ctccaaaaac caaccatcaa ggctgaacca ggctctgtga
      841 tccactctgg aaaggccatg atcatatggt gtcaggggga cctggatgca gaaatatatt
      901 ttctgcataa ggagggaagc cacaatacac agagcacaca gaccctacaa cagcctggga
      961 acaaggccaa gttattcatc cgtcctgtga cacaaggcca tgcaggggac tatcgctgtt
     1021 actattacag ctcggctggt tggtcagaac ccagtgacac cctggagctg gtggtgacag
     1081 gaatatacaa ctaccatcca ctcatgctgt caggaccgcc cagccctgtg gtgccagagg
     1141 gagggaacgt gacactccac tgtacctcac accgctacta tgataaattc attctcatca
     1201 aggaagatca gaagttcagc agctcactag acacaaagta tatatcttct actggacaac
     1261 accaagctct gtttgttatg ggacctatga ctccaaacta ctcagggaca ttcagatgct
     1321 atggttacta caagcatacc ccacagttgt ggtcagaacc cagtaacctc ttaaaaatac
     1381 tcatcacagg acagcttcat cacgttcttt tcctctcagt gatgcccaac tccacagtac
     1441 actcaggaga gaatgtgacc ctgatgtgtt ggtcaacgta ctctgtggac actttcattc
     1501 tgtccaagga gggatcaggc cagccacccc ttcgactaaa gtcaaagatc caagatcaac
     1561 agtaccagtc agaattctcc atgagtggtg tgacatccaa gctctcaggc acctacaggt
     1621 gctatggctc tcacgactca tctctctacc tgctgtcatt tgccagtgcc cctgtggagc
     1681 tcatagtctc aggacccatc agaacctctg acctgccacc cacaatgtcc ataccaccag
     1741 atggactgca aaggtacctg aaggctctga ttggagtgtc cgtggccttc ctcctgttcc
     1801 tcttcatcct catcttcatt cttctcagac gaagacatca ggaaaaattc aggaaggatg
     1861 atgaggatgc ccagaaaggg aaagaattac aactttctac aggagctgca gagccagtaa
     1921 ccagggacag aggccaccag aagaggtcaa acccagctgc tgccacccag gaagaaagcc
     1981 tttatgcttc agtggaggac atggaaacta aggatggtgt ggagctggac acttggaaac
     2041 cacctgaggg agatccccaa ggagagacat atgcccaggt ggaaccatcc aggctcagga
     2101 gggcgggagc tatctcacct gtcgtatcaa gggagcagct gaacacaaaa tatgaacaag
     2161 cagaagaggg ccaagaggtg gacagtcagg ctactgaatc tgaagagcct caggatgtga
     2221 cctatgccca gctgtgcagc aggacactca gacaggggac agctgcacct cctctctccc
     2281 aggcagggga agccccagag gagcccagtg tatatgctgc tctagcgact gctcgcccgg
     2341 gagctgttcc taagaacaag aagcagtgac actccagtga tcctggtagc ctgccaggat
     2401 gcctaccaga gacctccaag agactctggg aacttttgga aacctgactg cactaagtaa
     2461 tgtaaccgtt tggaaataaa ggcagatatt tctcaataa
//
