LOCUS       NM_001419491            2321 bp    mRNA    linear   ROD 10-APR-2024
DEFINITION  Rattus norvegicus paired-Ig-like receptor A2 (Pira2), mRNA.
ACCESSION   NM_001419491 XM_017589346
VERSION     NM_001419491.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2321)
  AUTHORS   Deng,X.H., Ai,W.M., Lei,D.L., Luo,X.G., Yan,X.X. and Li,Z.
  TITLE     Lipopolysaccharide induces paired immunoglobulin-like receptor B
            (PirB) expression, synaptic alteration, and learning-memory deficit
            in rats
  JOURNAL   Neuroscience 209, 161-170 (2012)
   PUBMED   22395112
  REMARK    GeneRIF: The results suggest that PirB modulation may be involved
            in the pathological process under neurodegenerative conditions
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Apr 4, 2023 this sequence version replaced XM_017589346.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF169638.1, AF169637.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMN06621351
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on manual assertion, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-60                JAXUCZ010000001.1  74331302-74331361
            61-96               JAXUCZ010000001.1  74331524-74331559
            97-381              JAXUCZ010000001.1  74331738-74332022
            382-687             JAXUCZ010000001.1  74332109-74332414
            688-972             JAXUCZ010000001.1  74333399-74333683
            973-1278            JAXUCZ010000001.1  74333810-74334115
            1279-1575           JAXUCZ010000001.1  74334338-74334634
            1576-1878           JAXUCZ010000001.1  74334877-74335179
            1879-1929           JAXUCZ010000001.1  74335409-74335459
            1930-2321           JAXUCZ010000001.1  74337817-74338208
FEATURES             Location/Qualifiers
     source          1..2321
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q12"
     gene            1..2321
                     /gene="Pira2"
                     /gene_synonym="Lilrb3; Lilrb3l; Pir-A1; Pir-A2; Pirb"
                     /note="paired-Ig-like receptor A2"
                     /db_xref="GeneID:361493"
                     /db_xref="RGD:1307219"
     exon            1..60
                     /gene="Pira2"
                     /gene_synonym="Lilrb3; Lilrb3l; Pir-A1; Pir-A2; Pirb"
                     /inference="alignment:Splign:2.1.0"
     CDS             27..2066
                     /gene="Pira2"
                     /gene_synonym="Lilrb3; Lilrb3l; Pir-A1; Pir-A2; Pirb"
                     /note="paired Ig-like receptor-B; paired Ig-like
                     receptor-A1; Ig-superfamily activating receptor; six
                     Ig-like domains/type I transmembrane; leukocyte
                     immunoglobulin-like receptor, subfamily B (with TM and
                     ITIM domains), member 3-like; leukocyte immunoglobulin
                     like receptor B3 like"
                     /codon_start=1
                     /product="paired-Ig-like receptor A2 precursor"
                     /protein_id="NP_001406420.1"
                     /db_xref="GeneID:361493"
                     /db_xref="RGD:1307219"
                     /translation="MTFTFTALICLGLTLGLWIPVLTGSLPKPILRAQPDSVVSMETK
                     VTFICEETIGAKESDLYRNGNLQRRVPKNNQKRTNKTEFLFLNVDQQNAGQYQCSYRT
                     QTKSSDYSEPLELVVTGAYSKPSLSAQTNPVVTSGGYVTLKCEPSQDNHTLILTVEGS
                     QKHSWRKDPECNRYTEKCHALFYVGPLTSNQRWIFRCYSYEKHTPQVWSAPSEPVELL
                     VSGKLQKTTIKAEPGSVIRSGRAMTIWCQGDLDAEIYFLHKEGSHNTQSTQTLQQPGN
                     KAKFLIPSVTQRHAGQYRCYCYSSAGWSEPSDTLELVVTGIYYYGVKLSGLPSPVVPE
                     GGNVTLHCTSHSNYDKFILTKEDQKFTSSLDAEYIPSTGQHQALFVMGPMTPNYSGTF
                     RCYGYYKHTPQLWSVPSELLKIFISGPSRKPSLLSHQGHILEPGMSLTLQCYSDTKYD
                     KFALYKEGGTDIIESFSQWTKAGLSMTNFTLGYGRHSTGGQYRCYGAHNLSSEWSASS
                     DPLDILITGQLDLAPSLSVMPNSTVHSGENVTLLCWSMYPVDTFILSKEGSGQPPLRR
                     KSKFQDQQYQSEFSMRAVTSKLSGTYRCYGSPDSSLYLLSFASAPVELIVSESIEASS
                     WPAKRFITTATPENQDHTTENLIRMGMAVLVLIVLSILAAEAWQSHRQTHHAAGK"
     exon            61..96
                     /gene="Pira2"
                     /gene_synonym="Lilrb3; Lilrb3l; Pir-A1; Pir-A2; Pirb"
                     /inference="alignment:Splign:2.1.0"
     exon            97..381
                     /gene="Pira2"
                     /gene_synonym="Lilrb3; Lilrb3l; Pir-A1; Pir-A2; Pirb"
                     /inference="alignment:Splign:2.1.0"
     exon            382..687
                     /gene="Pira2"
                     /gene_synonym="Lilrb3; Lilrb3l; Pir-A1; Pir-A2; Pirb"
                     /inference="alignment:Splign:2.1.0"
     exon            688..972
                     /gene="Pira2"
                     /gene_synonym="Lilrb3; Lilrb3l; Pir-A1; Pir-A2; Pirb"
                     /inference="alignment:Splign:2.1.0"
     exon            973..1278
                     /gene="Pira2"
                     /gene_synonym="Lilrb3; Lilrb3l; Pir-A1; Pir-A2; Pirb"
                     /inference="alignment:Splign:2.1.0"
     exon            1279..1575
                     /gene="Pira2"
                     /gene_synonym="Lilrb3; Lilrb3l; Pir-A1; Pir-A2; Pirb"
                     /inference="alignment:Splign:2.1.0"
     exon            1576..1878
                     /gene="Pira2"
                     /gene_synonym="Lilrb3; Lilrb3l; Pir-A1; Pir-A2; Pirb"
                     /inference="alignment:Splign:2.1.0"
     exon            1879..1929
                     /gene="Pira2"
                     /gene_synonym="Lilrb3; Lilrb3l; Pir-A1; Pir-A2; Pirb"
                     /inference="alignment:Splign:2.1.0"
     exon            1930..2321
                     /gene="Pira2"
                     /gene_synonym="Lilrb3; Lilrb3l; Pir-A1; Pir-A2; Pirb"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agttgcagcc tctgagagga gatgccatga ccttcacctt cacagccctg atctgtcttg
       61 gactgactct gggcctctgg atcccagtgc tgacagggtc cctccctaaa cctatcctca
      121 gagcacagcc agattctgtg gtctcaatgg aaactaaggt gaccttcatt tgtgaggaga
      181 ccattggagc caaagagtct gatctctata gaaatggaaa cctacagaga agagttccaa
      241 agaacaatca gaaacgaaca aacaagactg aattcttatt cttaaatgta gaccagcaaa
      301 atgcagggca atatcaatgc tcctacagga ctcagactaa gtcatcagac tacagtgagc
      361 ccctggagct agtggtcaca ggagcctact cgaaacccag cctttcagcc cagaccaacc
      421 ctgtggtgac ctcaggaggg tatgtcaccc tcaaatgtga gccctcacag gacaatcaca
      481 cgttgattct tactgtagaa ggatctcaga aacactcctg gaggaaggac ccagagtgta
      541 accgctatac tgagaagtgt catgccctgt tctatgtggg ccctttgacc tccaaccaga
      601 gatggatatt cagatgctac agctatgaaa aacacacacc acaagtgtgg tcagctccta
      661 gtgaaccagt ggagctcctg gtgtcaggga aactgcaaaa aacaaccatc aaggctgaac
      721 caggctctgt gatccgctct ggaagagcca tgaccatctg gtgtcagggg gacctggatg
      781 cagaaatata ttttctgcat aaggagggaa gccacaatac acagagcaca cagaccctac
      841 aacagcctgg gaacaaggcc aagttcctca tcccttctgt gacacaaagg catgcagggc
      901 aatatcgctg ctactgttac agctcagctg gctggtcaga gcccagtgac accctggagc
      961 tggtggtgac aggaatctac tactatggag tcaagctgtc aggactgccc agccctgtgg
     1021 tgccagaggg agggaacgta acactccact gtacctcaca cagcaactat gataaattca
     1081 ttctcaccaa ggaagatcag aagttcacca gctcactaga cgcagagtat ataccttcta
     1141 ctggacaaca ccaagccctg tttgttatgg gacctatgac tccaaactac tcagggacat
     1201 tcagatgtta tggttactac aagcataccc cacagttgtg gtcagtaccc agtgagctcc
     1261 taaaaatatt catctcagga ccatcgagga agccctctct gctaagtcat caaggccata
     1321 tactggaacc tggaatgagc ctcacactgc agtgttactc tgacaccaag tatgacaaat
     1381 ttgctctgta caaagaaggg ggaactgaca tcatagaatc ctttagccag tggaccaagg
     1441 ctggcctctc catgaccaac ttcacactgg gctatgggag acactccact ggaggccaat
     1501 acagatgcta tggtgcacac aacctctcct ctgagtggtc agcctccagt gaccccctgg
     1561 acatcctgat cacaggacag cttgatctcg ctccttccct ctcagtgatg cctaactcca
     1621 cagtacactc aggagagaat gtgaccctgc tgtgttggtc aatgtaccct gtggacactt
     1681 tcattctgtc aaaggaggga tcaggccagc caccccttcg acgaaagtca aagttccaag
     1741 atcaacagta ccagtcagaa ttctccatga gagctgtgac atccaagctc tcgggcacct
     1801 acaggtgcta tggttctccc gactcatctc tctacctgtt gtcatttgcc agtgcccctg
     1861 tggagctcat agtctcagaa tccatcgaag cctccagctg gccagctaaa aggttcatca
     1921 caacagccac cccagaaaac caggatcaca caacggagaa tctcatcagg atgggaatgg
     1981 ctgtcctggt cctcatagtc ctttcgattc tagctgctga ggcctggcaa agtcatagac
     2041 agacccacca cgcagctggc aaataatcta aagagaaagg acagctttca atgttctaca
     2101 ctctgcgaaa tgaatctgat gatccaaaat tttctgtcag aaaaatgcgt tgtgatagaa
     2161 gtccagggag caaaactgtt tggggttctg aggcaagaag ttttatgatg aggtgattcc
     2221 ttgttaaaca aatatttgtc cctcatgtac tgggggtctt tgcttcctga acccacactc
     2281 ttctgaaact ataaaataat aaaatatttt gtcccatctg a
//
