LOCUS       NM_001012009            1716 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus pipecolic acid and sarcosine oxidase (Pipox),
            mRNA.
ACCESSION   NM_001012009 XM_220642
VERSION     NM_001012009.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1716)
  AUTHORS   Ghosh D and Berg JM.
  TITLE     A proteome-wide perspective on peroxisome targeting signal
            1(PTS1)-Pex5p affinities
  JOURNAL   J Am Chem Soc 132 (11), 3973-3979 (2010)
   PUBMED   20178365
REFERENCE   2  (bases 1 to 1716)
  AUTHORS   Kikuchi M, Hatano N, Yokota S, Shimozawa N, Imanaka T and Taniguchi
            H.
  TITLE     Proteomic analysis of rat liver peroxisome: presence of
            peroxisome-specific isozyme of Lon protease
  JOURNAL   J Biol Chem 279 (1), 421-428 (2004)
   PUBMED   14561759
REFERENCE   3  (bases 1 to 1716)
  AUTHORS   Dodt G, Kim DG, Reimann SA, Reuber BE, McCabe K, Gould SJ and
            Mihalik SJ.
  TITLE     L-Pipecolic acid oxidase, a human enzyme essential for the
            degradation of L-pipecolic acid, is most similar to the monomeric
            sarcosine oxidases
  JOURNAL   Biochem J 345 Pt 3 (Pt 3), 487-494 (2000)
   PUBMED   10642506
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC088249.1.
            
            On Feb 11, 2005 this sequence version replaced XM_220642.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC088249.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760494 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1716
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q24"
     gene            1..1716
                     /gene="Pipox"
                     /note="pipecolic acid and sarcosine oxidase"
                     /db_xref="GeneID:303272"
                     /db_xref="RGD:1311347"
     exon            1..120
                     /gene="Pipox"
                     /inference="alignment:Splign:2.1.0"
     CDS             7..1179
                     /gene="Pipox"
                     /note="pipecolic acid oxidase"
                     /codon_start=1
                     /product="peroxisomal sarcosine oxidase"
                     /protein_id="NP_001012009.1"
                     /db_xref="GeneID:303272"
                     /db_xref="RGD:1311347"
                     /translation="MAAQTDLWDAIVIGAGVQGCFTAYHLAQNSKKVLLLEQFLLPHS
                     RGSSHGQSRIIRKAYPEDFYTRMMDECYRTWAQLEREAGAQLHRRTELLFLGMKENPG
                     LKTIQATLSRQGIDHECLSSVHLKQRFPNIRFTKGEVGLLDKTGGVLYADKALRALQH
                     VIRQLGGMVCDGEKVVEIRPGLPVTVKTTLKSYQANSLVITAGPWTNRILRPLGIELP
                     LQTLRINVCYWREKVPGSYSVSQAFPCILSLDLAPHHIYGLPASEYPGLMKVCYHHGD
                     SVDPEERDCPKTFSDIQDVQILCHFVKDHLPGLRPEPDIMERCMYTNTPDEHFILDCH
                     PKYDNIVIGAGFSGHGFKLAPAVGKVLYELSMKLPPSYDLAPFRISRFSKLSKAHL"
     exon            121..269
                     /gene="Pipox"
                     /inference="alignment:Splign:2.1.0"
     exon            270..483
                     /gene="Pipox"
                     /inference="alignment:Splign:2.1.0"
     exon            484..666
                     /gene="Pipox"
                     /inference="alignment:Splign:2.1.0"
     exon            667..813
                     /gene="Pipox"
                     /inference="alignment:Splign:2.1.0"
     exon            814..972
                     /gene="Pipox"
                     /inference="alignment:Splign:2.1.0"
     exon            973..1048
                     /gene="Pipox"
                     /inference="alignment:Splign:2.1.0"
     exon            1049..1692
                     /gene="Pipox"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcatcatgg ctgctcagac agatctctgg gatgctattg tgattggagc aggcgtccag
       61 ggctgtttta ccgcgtacca cctggcccag aattccaaga aggtcctcct gctggagcag
      121 ttccttcttc cccattcccg aggaagctca catggacaga gccgcataat cagaaaggct
      181 taccccgagg acttctacac aaggatgatg gatgaatgtt atcggacatg ggcccagctg
      241 gagcgtgaag ctggagccca gttgcacagg cggactgaac tcttgtttct gggaatgaag
      301 gaaaatccag gattaaagac aatccaggcc actctgtcta ggcaggggat tgaccacgag
      361 tgcctttcat cagtgcattt aaagcaacgc tttccaaaca ttcggttcac caagggagaa
      421 gtagggctct tagacaagac tggaggtgtt ctctatgcag acaaggccct cagagccctc
      481 cagcatgtaa ttcgtcagct aggaggcatg gtgtgtgatg gagagaaggt agtggagata
      541 agacctggtc tacctgtcac agtgaaaacc accttgaaga gctaccaagc caacagcttg
      601 gtcatcactg ctggtccctg gaccaaccgg attcttcgtc ccctgggaat tgagttgcct
      661 ctccagaccc ttcggatcaa tgtgtgttac tggcgagaga aggtccctgg gagctatagt
      721 gtgtcacaag ctttcccatg catcctgagt ctggatctgg ccccccacca catctacgga
      781 ctgccagcct cagagtaccc agggctgatg aaggtgtgct atcaccatgg tgacagtgtg
      841 gacccagagg agcgggactg ccccaaaacc ttctcagaca tccaagacgt tcagattcta
      901 tgccactttg tcaaagatca tttaccaggc ctgaggccag agccagacat catggaacgc
      961 tgcatgtaca cgaatactcc cgatgagcac tttattcttg actgccaccc aaagtatgac
     1021 aacattgtca tcggtgctgg attctctggt catggattca agttggcccc tgctgtgggg
     1081 aaggtcctct atgagctaag catgaaatta ccaccatcct atgacttggc tccatttcga
     1141 ataagccgct tctctaagct gagcaaagcc cacctttgac cccagctgac tgtctcctgg
     1201 gcaggaaagc cctcctaggg aagacttcta agagaaggat gtcaccttga gtttcttttc
     1261 ctcctgtttc agtgggatct cccgtaaaca ccaaatgatt gaacctcttt ccccaatcag
     1321 cttcccaagt ctatctcatt tcttcttccc agaaagtcag cgagactcag agactcacca
     1381 tcacagaaca gcaaggagct ttaagatgga tgtcccaatg gggaggggct cgagacggct
     1441 cagtagacta agggactcct ttaaatttct ctttgctggg acactggata aatgtgagat
     1501 agccttgact aaatctgctc aggggaatgt aaaaaaggta tcttttataa accactagtg
     1561 cctttggggt ttctttgcca aaatcttgag ccagcctcta ccactaagtc tcataaagtc
     1621 tcacctctaa taaataaaca tttgccagga aaataaaagg ttgctgaaaa caataaacaa
     1681 aaatctggat taaaaaaaaa aaaaaaaaaa aaaaaa
//
