LOCUS       NM_001024900            2255 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus phosphatidylinositol-4,5-bisphosphate
            4-phosphatase 2 (Pip4p2), mRNA.
ACCESSION   NM_001024900 XM_342809
VERSION     NM_001024900.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2255)
  AUTHORS   Morioka,S., Nigorikawa,K., Okada,E., Tanaka,Y., Kasuu,Y.,
            Yamada,M., Kofuji,S., Takasuga,S., Nakanishi,H., Sasaki,T. and
            Hazeki,K.
  TITLE     TMEM55a localizes to macrophage phagosomes to downregulate
            phagocytosis
  JOURNAL   J Cell Sci 131 (5) (2018)
   PUBMED   29378918
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2255)
  AUTHORS   Ungewickell,A., Hugge,C., Kisseleva,M., Chang,S.C., Zou,J.,
            Feng,Y., Galyov,E.E., Wilson,M. and Majerus,P.W.
  TITLE     The identification and characterization of two
            phosphatidylinositol-4,5-bisphosphate 4-phosphatases
  JOURNAL   Proc Natl Acad Sci U S A 102 (52), 18854-18859 (2005)
   PUBMED   16365287
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC097492.1.
            
            On Jun 17, 2005 this sequence version replaced XM_342809.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC097492.1, DN931630.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132263
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2255
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q13"
     gene            1..2255
                     /gene="Pip4p2"
                     /gene_synonym="RGD1306225; Tmem55a"
                     /note="phosphatidylinositol-4,5-bisphosphate 4-phosphatase
                     2"
                     /db_xref="GeneID:362490"
                     /db_xref="RGD:1306225"
     exon            1..168
                     /gene="Pip4p2"
                     /gene_synonym="RGD1306225; Tmem55a"
                     /inference="alignment:Splign:2.1.0"
     CDS             63..836
                     /gene="Pip4p2"
                     /gene_synonym="RGD1306225; Tmem55a"
                     /EC_number="3.1.3.78"
                     /note="ptdIns-4,5-P2 4-Ptase II; type II
                     phosphatidylinositol 4,5-bisphosphate 4-phosphatase; type
                     2 PtdIns-4,5-P2 4-Ptase; transmembrane protein 55A"
                     /codon_start=1
                     /product="type 2 phosphatidylinositol 4,5-bisphosphate
                     4-phosphatase"
                     /protein_id="NP_001020071.1"
                     /db_xref="GeneID:362490"
                     /db_xref="RGD:1306225"
                     /translation="MAADGVDERSPLLSASHSGNVTPTAPPYLQESSPRAELPPPYTA
                     IASPGTSGIPVINCRVCQSLINLDGKLHQHVVKCTVCNEATPIKTPPTGKKYVRCPCN
                     CLLICKDTSRRIGCPRPNCRRIINLGPIMLISEEQPAQPALPVQPEGTRVVCGHCGNT
                     FLWMELRFNTLAKCPHCKKISSVGSALPRRRCCAYVTIGMICIFIGVGLTVGTQDFSR
                     RFHATYVSWAIAYLLGLICLIRACYWGAIRVSYPEHGFA"
     exon            169..317
                     /gene="Pip4p2"
                     /gene_synonym="RGD1306225; Tmem55a"
                     /inference="alignment:Splign:2.1.0"
     exon            318..424
                     /gene="Pip4p2"
                     /gene_synonym="RGD1306225; Tmem55a"
                     /inference="alignment:Splign:2.1.0"
     exon            425..548
                     /gene="Pip4p2"
                     /gene_synonym="RGD1306225; Tmem55a"
                     /inference="alignment:Splign:2.1.0"
     exon            549..601
                     /gene="Pip4p2"
                     /gene_synonym="RGD1306225; Tmem55a"
                     /inference="alignment:Splign:2.1.0"
     exon            602..692
                     /gene="Pip4p2"
                     /gene_synonym="RGD1306225; Tmem55a"
                     /inference="alignment:Splign:2.1.0"
     exon            693..2219
                     /gene="Pip4p2"
                     /gene_synonym="RGD1306225; Tmem55a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctcctcccta gccgcaaccc agctcaaccc gcggcccgcc gcgctgtgct gttgctgcag
       61 tcatggctgc tgacggggtg gacgaacgtt cgcctctgct gtcagcatcc cattcgggca
      121 atgtcactcc cacagccccg ccgtacttgc aagaaagcag cccaagagct gaactcccac
      181 ctccgtatac agccatcgcc agtccaggaa caagcggtat tcccgtcatc aactgtcgcg
      241 tgtgccaatc gctcatcaac ctggatggta aacttcacca gcatgtggtt aagtgcacag
      301 tttgtaatga agctacgcca atcaaaaccc ccccgacagg gaagaaatat gttagatgcc
      361 cttgtaattg tctcctcatt tgtaaggaca catctcggcg aataggatgt cctagaccca
      421 actgtcgacg cataatcaac cttggcccca taatgctcat ttctgaagag caaccggctc
      481 aacctgcgct gccagtccag ccggaaggta caagggtagt gtgcgggcac tgcgggaaca
      541 cgttcctgtg gatggaactg aggttcaaca ctctggcaaa atgcccacac tgcaaaaaaa
      601 tctcctcggt gggtagcgcc cttccccgga gacgctgctg tgcatacgtc accatcggaa
      661 tgatatgtat tttcattgga gttgggttaa ctgttggcac acaagatttt tcaaggcgat
      721 ttcatgcaac ttatgtgtct tgggcaattg cttatctgtt aggtttgatt tgccttatcc
      781 gagcttgtta ctggggtgca atcagagtca gttatccaga gcacggtttt gcttaagtct
      841 tctcatgaac ccttgatgca ggtgagagtg tccagtcgtc cttgtgaagc tcttctggac
      901 accttcaaat catttatcct aatggagtcc atcctggttt gtatagtagt ctctcaagac
      961 tttgtgagtc ttttctgatc agatgctcac tgaagtacat gatatgcaag ttcattttgc
     1021 tgctaggttt tcagacttgg aaaaataaag ccgtgtcttt gttctttcaa atcataaagg
     1081 tatttttgca tttgtcctca aatgttatat ctaatatcag tctttcatta tttttcaacc
     1141 agttgttcca ttacttgttg atgtgggact attcccgaga agtgtttata aatgtttcta
     1201 taataggttc acatttatac ttacatttta aacaattgct tgctttaaaa tctaagcaat
     1261 atgcattttt gcttgaactg cttactgtaa ttttaaccta agagtatagc taccttattc
     1321 aggaaaacag aaaattgagt gtactttaaa aaacttgaca ttcttgtcag agaaacattt
     1381 ctagatacta tatgcttgtt ttttgttgtt gttgtttgta gaaagataca atattttggt
     1441 agtaaattaa aatacttagg atgaacatat agtccacagt tggagatgtt agataaatgt
     1501 cttttctcta agattacagg acttttgcct ttcagttctt tctttttatt tagcatttac
     1561 aaaaatctgg tctggattta tggaatttaa tgttactctg ctgaatgtat tccttgatgg
     1621 actggaggaa gtatttcaga caacatgttt tataatactt catcatctcg tcggagacat
     1681 gttgacactg ggttgcagtc cttttcatta gatcatggta aactttcttc ttgaaatatg
     1741 tgtacacctg cttctctgtg aagagaactt acgacttttt gcattagctg aaatgttaga
     1801 attagagatt ctcttaccat ttctcacctg gccagataat gactcaactt cttcaagaga
     1861 atggatcaga gataaagagc ttcattgttg tctaaaactt tgtgtgagat tcgaggactc
     1921 agcccttgca ctgcccagtt ttgcggttta gaaggaattc cttgagagtc agtggtctaa
     1981 actctttcac attgtaaaat tagacagtga gacacccaga gtacgttagt aggtgattcc
     2041 aagggacaag actaatgttc taaattattt atattcctga ttaatatgaa aatgtactta
     2101 ctgcgaagtt ggagtcaact acatgtacac ctcagagaga aaatgataaa tgtataaatg
     2161 tagtagctca ggattatatg tacctttgaa aatatgctaa taaagattat tattcaaaaa
     2221 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa
//
