LOCUS       NM_022708                557 bp    mRNA    linear   ROD 02-FEB-2024
DEFINITION  Rattus norvegicus prolactin induced protein (Pip), mRNA.
ACCESSION   NM_022708
VERSION     NM_022708.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 557)
  AUTHORS   Morzel,M., Chabanet,C., Schwartz,C., Lucchi,G., Ducoroy,P. and
            Nicklaus,S.
  TITLE     Salivary protein profiles are linked to bitter taste acceptance in
            infants
  JOURNAL   Eur J Pediatr 173 (5), 575-582 (2014)
   PUBMED   24248522
REFERENCE   2  (bases 1 to 557)
  AUTHORS   Pieragostino,D., Agnifili,L., Fasanella,V., D'Aguanno,S.,
            Mastropasqua,R., Di Ilio,C., Sacchetta,P., Urbani,A. and Del
            Boccio,P.
  TITLE     Shotgun proteomics reveals specific modulated protein patterns in
            tears of patients with primary open angle glaucoma naive to therapy
  JOURNAL   Mol Biosyst 9 (6), 1108-1116 (2013)
   PUBMED   23580065
REFERENCE   3  (bases 1 to 557)
  AUTHORS   Todd,M.A. and Picketts,D.J.
  TITLE     PHF6 interacts with the nucleosome remodeling and deacetylation
            (NuRD) complex
  JOURNAL   J Proteome Res 11 (8), 4326-4337 (2012)
   PUBMED   22720776
REFERENCE   4  (bases 1 to 557)
  AUTHORS   Bohm,D., Keller,K., Pieter,J., Boehm,N., Wolters,D., Siggelkow,W.,
            Lebrecht,A., Schmidt,M., Kolbl,H., Pfeiffer,N. and Grus,F.H.
  TITLE     Comparison of tear protein levels in breast cancer patients and
            healthy controls using a de novo proteomic approach
  JOURNAL   Oncol Rep 28 (2), 429-438 (2012)
   PUBMED   22664934
REFERENCE   5  (bases 1 to 557)
  AUTHORS   Kurokawa,S., Kojima,Y., Mizuno,K., Kamisawa,H., Tozawa,K., Kohri,K.
            and Hayashi,Y.
  TITLE     Association of prolactin-induced protein with preputial development
            of hypospadias
  JOURNAL   BJU Int 109 (6), 926-932 (2012)
   PUBMED   21883842
  REMARK    GeneRIF: Pip/PIP, expressed at low levels in the genital tubercles
            of hypospadiac rats, may be associated with preputial development.
REFERENCE   6  (bases 1 to 557)
  AUTHORS   Palmer,D.J., Kelly,V.C., Smit,A.M., Kuy,S., Knight,C.G. and
            Cooper,G.J.
  TITLE     Human colostrum: identification of minor proteins in the aqueous
            phase by proteomics
  JOURNAL   Proteomics 6 (7), 2208-2216 (2006)
   PUBMED   16502470
REFERENCE   7  (bases 1 to 557)
  AUTHORS   Chiu,W.W. and Chamley,L.W.
  TITLE     Human seminal plasma prolactin-inducible protein is an
            immunoglobulin G-binding protein
  JOURNAL   J Reprod Immunol 60 (2), 97-111 (2003)
   PUBMED   14638438
REFERENCE   8  (bases 1 to 557)
  AUTHORS   Caputo,E., Manco,G., Mandrich,L. and Guardiola,J.
  TITLE     A novel aspartyl proteinase from apocrine epithelia and breast
            tumors
  JOURNAL   J Biol Chem 275 (11), 7935-7941 (2000)
   PUBMED   10713110
REFERENCE   9  (bases 1 to 557)
  AUTHORS   Gaubin,M., Autiero,M., Basmaciogullari,S., Metivier,D., Mis hal,Z.,
            Culerrier,R., Oudin,A., Guardiola,J. and Piatier-Tonneau,D.
  TITLE     Potent inhibition of CD4/TCR-mediated T cell apoptosis by a
            CD4-binding glycoprotein secreted from breast tumor and seminal
            vesicle cells
  JOURNAL   J Immunol 162 (5), 2631-2638 (1999)
   PUBMED   10072505
REFERENCE   10 (bases 1 to 557)
  AUTHORS   Mirels,L., Hand,A.R. and Branin,H.J.
  TITLE     Expression of gross cystic disease fluid
            protein-15/Prolactin-inducible protein in rat salivary glands
  JOURNAL   J Histochem Cytochem 46 (9), 1061-1071 (1998)
   PUBMED   9705972
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF054270.1.
            
            [WARNING] On Aug 19, 2024 this sequence was replaced by
            NM_022708.3.
            
            On Feb 21, 2013 this sequence version replaced NM_022708.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF054270.1, BF525265.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-557               AF054270.1         1-557
FEATURES             Location/Qualifiers
     source          1..557
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q24"
     gene            1..557
                     /gene="Pip"
                     /note="prolactin induced protein"
                     /db_xref="GeneID:64673"
                     /db_xref="RGD:70946"
     exon            1..105
                     /gene="Pip"
                     /inference="alignment:Splign:2.1.0"
     CDS             17..457
                     /gene="Pip"
                     /note="prolactin-inducible protein homolog"
                     /codon_start=1
                     /product="prolactin-inducible protein homolog precursor"
                     /protein_id="NP_073199.1"
                     /db_xref="GeneID:64673"
                     /db_xref="RGD:70946"
                     /translation="MQGLSFTSTAATFFLVLCLQLGINEGQDNETIPQPLLFQLNVPS
                     TPDENQEVDMSLTLQTQYKECLVVKAYLISNTPVDGGFNYIQTRCICNDHPTTLYWTF
                     VVTQTLTFRIMVDIVKDKGICPNNVAVVPISGNRYFTDRTVYVN"
     exon            106..217
                     /gene="Pip"
                     /inference="alignment:Splign:2.1.0"
     exon            218..332
                     /gene="Pip"
                     /inference="alignment:Splign:2.1.0"
     exon            333..557
                     /gene="Pip"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcctgatttc ttcaccatgc aaggtctctc attcacatcc actgctgcca ccttcttctt
       61 ggtcctctgt ctgcaactgg ggatcaatga aggccaggat aatgaaacta ttccacagcc
      121 acttttattt caactaaatg ttccaagtac acctgacgaa aatcaggagg ttgatatgtc
      181 acttactctt caaacacaat ataaagaatg tctggtggtc aaagcttacc ttataagtaa
      241 tacaccggtt gatggtggct tcaactatat acaaacacgc tgcatctgca atgatcatcc
      301 taccaccctt tactggactt ttgtagtcac tcaaacttta acatttagaa taatggttga
      361 cattgttaag gataaaggta tctgccctaa taacgtcgca gtggtgccca tctcaggaaa
      421 ccggtacttc acagaccgta ctgtgtacgt gaattaacaa aggcttctta tgcatctttc
      481 aaaaccatta tcattttctc taagtaaaat tgactggaat acccattgta atctgttaaa
      541 tgaacttctt ataagcg
//
