LOCUS       NM_001191923            3031 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus phosphoinositide-3-kinase, regulatory subunit 5
            (Pik3r5), mRNA.
ACCESSION   NM_001191923 XM_573118
VERSION     NM_001191923.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3031)
  AUTHORS   Voigt,P., Brock,C., Nurnberg,B. and Schaefer,M.
  TITLE     Assigning functional domains within the p101 regulatory subunit of
            phosphoinositide 3-kinase gamma
  JOURNAL   J Biol Chem 280 (6), 5121-5127 (2005)
   PUBMED   15611065
REFERENCE   2  (bases 1 to 3031)
  AUTHORS   Kondo,Y., Shen,L., Yan,P.S., Huang,T.H. and Issa,J.P.
  TITLE     Chromatin immunoprecipitation microarrays for identification of
            genes silenced by histone H3 lysine 9 methylation
  JOURNAL   Proc Natl Acad Sci U S A 101 (19), 7398-7403 (2004)
   PUBMED   15123805
REFERENCE   3  (bases 1 to 3031)
  AUTHORS   Kaplan-Albuquerque,N., Garat,C., Desseva,C., Jones,P.L. and
            Nemenoff,R.A.
  TITLE     Platelet-derived growth factor-BB-mediated activation of Akt
            suppresses smooth muscle-specific gene expression through
            inhibition of mitogen-activated protein kinase and redistribution
            of serum response factor
  JOURNAL   J Biol Chem 278 (41), 39830-39838 (2003)
   PUBMED   12882977
REFERENCE   4  (bases 1 to 3031)
  AUTHORS   Brock,C., Schaefer,M., Reusch,H.P., Czupalla,C., Michalke,M.,
            Spicher,K., Schultz,G. and Nurnberg,B.
  TITLE     Roles of G beta gamma in membrane recruitment and activation of
            p110 gamma/p101 phosphoinositide 3-kinase gamma
  JOURNAL   J Cell Biol 160 (1), 89-99 (2003)
   PUBMED   12507995
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Jul 17, 2010 this sequence version replaced XM_573118.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643292.41152.1,
                                           SRR26643297.34421.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760434
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-103               JAXUCZ010000010.1  53677832-53677934
            104-204             JAXUCZ010000010.1  53679383-53679483
            205-273             JAXUCZ010000010.1  53680324-53680392
            274-412             JAXUCZ010000010.1  53681376-53681514
            413-482             JAXUCZ010000010.1  53689796-53689865
            483-657             JAXUCZ010000010.1  53691666-53691840
            658-811             JAXUCZ010000010.1  53692376-53692529
            812-895             JAXUCZ010000010.1  53693479-53693562
            896-1598            JAXUCZ010000010.1  53693895-53694597
            1599-1761           JAXUCZ010000010.1  53694723-53694885
            1762-1887           JAXUCZ010000010.1  53695202-53695327
            1888-2016           JAXUCZ010000010.1  53695826-53695954
            2017-2110           JAXUCZ010000010.1  53696119-53696212
            2111-2187           JAXUCZ010000010.1  53696451-53696527
            2188-2281           JAXUCZ010000010.1  53696735-53696828
            2282-2364           JAXUCZ010000010.1  53696907-53696989
            2365-2477           JAXUCZ010000010.1  53697468-53697580
            2478-3031           JAXUCZ010000010.1  53697708-53698261
FEATURES             Location/Qualifiers
     source          1..3031
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q24"
     gene            1..3031
                     /gene="Pik3r5"
                     /gene_synonym="RGD1563261"
                     /note="phosphoinositide-3-kinase, regulatory subunit 5"
                     /db_xref="GeneID:497931"
                     /db_xref="RGD:1563261"
     CDS             1..2619
                     /gene="Pik3r5"
                     /gene_synonym="RGD1563261"
                     /note="phosphoinositide-3-kinase, regulatory subunit 5,
                     p101"
                     /codon_start=1
                     /product="phosphoinositide 3-kinase regulatory subunit 5"
                     /protein_id="NP_001178852.1"
                     /db_xref="GeneID:497931"
                     /db_xref="RGD:1563261"
                     /translation="MQPAATTCTEDRIQHALERCLHGLSLGRRSAPWSAGLCLNCWSL
                     QELVSRDPGHFLILLEQILQKTQEVQEKGTYDLLAPLALLFYSTVLCTPHFPPDSDLL
                     LKAASTYHCFLTWPVPYCSICREMLTFIDAELKAPGISYQRLVRAEQGLPIRSHRSST
                     VTVLLLNPVEVQAEFLAVADKLSTPGQSPHGAYTTLLLHAFQATFGTHCDLPKLHRKL
                     QSKTLEELEDIFTETTEAQELASGIGDVAEARQWLRTKLQAVGEKAGFPGILDTASPG
                     KLHTIPIPVARCYTYSWNQDSFDILQEVLLKEQELLQPGILGDDEEEEEEDLEIDRHI
                     AERDSLLSTGSLVSHDSELLLTSSQASGPVLSRQVLTTFVSGLSDGMDSGYVEDSEES
                     SSEWPKKPGSQQRQGHRRPRQKFNRFYKLLKSTSQLVLRRDSRSLECSPDPTLPLRRA
                     GSLSSPLDFPTQLPSRAQRSRSLPQPKLSTQLPSWLLAPPSHHQRRRPFLSGDEDPKA
                     STLRVVVFGSDRISGKVARAYSKLRRLENSHPILTRFFKLQFFYVPVKRSHGASSSAC
                     LSSLNQASPLLPDSLKHPSPADLGKAPWEDSTNDISHYLGMLDPWYERNVLGLMHLPP
                     EVLCQQSLKAESRPLEGSATQLPILADMLLYYCRFAARPVLLQVYQTELTFVTGEKTT
                     EIFIQSLELGHSATTRAIKASGPGSKRLGIGDDREAVPLTLQIIYSKGAISGRSRWSN
                     LEKVCTSVNLSKACQKPEELDSSMEALTLTLTEVVKRQNPKSKKGFNQISTSYIKVDK
                     VQIISSSSCPFAVCLDQDERKILQSVVRCEVSPCYKPEKSSLPPEGSLSQPAEAGSDL
                     CSLLCLPIMTFSGALP"
     exon            1..103
                     /gene="Pik3r5"
                     /gene_synonym="RGD1563261"
                     /inference="alignment:Splign:2.1.0"
     exon            104..204
                     /gene="Pik3r5"
                     /gene_synonym="RGD1563261"
                     /inference="alignment:Splign:2.1.0"
     exon            205..273
                     /gene="Pik3r5"
                     /gene_synonym="RGD1563261"
                     /inference="alignment:Splign:2.1.0"
     exon            274..412
                     /gene="Pik3r5"
                     /gene_synonym="RGD1563261"
                     /inference="alignment:Splign:2.1.0"
     exon            413..482
                     /gene="Pik3r5"
                     /gene_synonym="RGD1563261"
                     /inference="alignment:Splign:2.1.0"
     exon            483..657
                     /gene="Pik3r5"
                     /gene_synonym="RGD1563261"
                     /inference="alignment:Splign:2.1.0"
     exon            658..811
                     /gene="Pik3r5"
                     /gene_synonym="RGD1563261"
                     /inference="alignment:Splign:2.1.0"
     exon            812..895
                     /gene="Pik3r5"
                     /gene_synonym="RGD1563261"
                     /inference="alignment:Splign:2.1.0"
     exon            896..1598
                     /gene="Pik3r5"
                     /gene_synonym="RGD1563261"
                     /inference="alignment:Splign:2.1.0"
     exon            1599..1761
                     /gene="Pik3r5"
                     /gene_synonym="RGD1563261"
                     /inference="alignment:Splign:2.1.0"
     exon            1762..1887
                     /gene="Pik3r5"
                     /gene_synonym="RGD1563261"
                     /inference="alignment:Splign:2.1.0"
     exon            1888..2016
                     /gene="Pik3r5"
                     /gene_synonym="RGD1563261"
                     /inference="alignment:Splign:2.1.0"
     exon            2017..2110
                     /gene="Pik3r5"
                     /gene_synonym="RGD1563261"
                     /inference="alignment:Splign:2.1.0"
     exon            2111..2187
                     /gene="Pik3r5"
                     /gene_synonym="RGD1563261"
                     /inference="alignment:Splign:2.1.0"
     exon            2188..2281
                     /gene="Pik3r5"
                     /gene_synonym="RGD1563261"
                     /inference="alignment:Splign:2.1.0"
     exon            2282..2364
                     /gene="Pik3r5"
                     /gene_synonym="RGD1563261"
                     /inference="alignment:Splign:2.1.0"
     exon            2365..2477
                     /gene="Pik3r5"
                     /gene_synonym="RGD1563261"
                     /inference="alignment:Splign:2.1.0"
     exon            2478..3031
                     /gene="Pik3r5"
                     /gene_synonym="RGD1563261"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgcagccag cagccacaac gtgcacagag gaccgcatcc agcacgctct ggagagatgc
       61 ttgcatggac tgagcctcgg acgccgttct gctccctggt cagccgggct gtgtctgaac
      121 tgctggagcc tacaggagct ggtcagcagg gacccgggcc acttcctcat cctcctggaa
      181 cagatcctgc agaagaccca agaggtccaa gagaagggca cctatgacct cctcgcccct
      241 ctggctctgc tcttctattc cactgtcctc tgcactccac acttcccacc agactcagac
      301 ctcctgctga aggcagccag cacctaccac tgcttcctga cctggccggt tccctactgc
      361 agcatctgcc gagagatgct caccttcatc gatgctgagc tcaaggcccc aggaatctcc
      421 taccagcggc tggtgagggc tgaacagggc ctgcccatca ggagccaccg aagttccact
      481 gtcactgtgc tgttgctgaa cccggtagag gtacaggctg agttcctcgc tgtggcagac
      541 aagctgagca caccgggaca gtcaccccat ggcgcctaca ccaccctgct cctgcatgcc
      601 ttccaggcca cctttgggac ccactgtgac cttcctaaac tgcaccgcaa acttcagtcc
      661 aagacgctag aagagctcga ggacatcttc actgagacta cagaagccca ggagctggca
      721 tctggcattg gggatgtagc agaggcccgt cagtggctcc ggaccaagct gcaggcagtg
      781 ggagaaaaag ccggcttccc cgggatctta gacactgcaa gccctgggaa actccacacg
      841 attcccatcc ctgtcgccag atgctacact tacagctgga atcaggacag ctttgacatc
      901 ctacaggaag tccttctcaa ggagcaggag ttgctgcagc cagggatcct gggagatgat
      961 gaagaggagg aagaggagga cttggagatt gacaggcata ttgctgagag ggactccctg
     1021 ctctccacag gctctctggt gtctcacgac tccgaactgt tgcttacctc ctctcaggcc
     1081 tcaggaccag tgctgtcccg ccaggtgctg accacctttg tctcaggcct ctcggatggc
     1141 atggacagtg gctacgttga ggacagtgag gaaagctcct cagagtggcc caagaagccg
     1201 ggcagccagc agcgccaggg tcaccgcagg cctaggcaga agttcaacag gttctataaa
     1261 cttttaaaga gcaccagcca gttggtcctg aggagggact ctcggagtct ggaatgcagc
     1321 ccagacccaa ccctgcctct gcggcgggca gggagcctca gcagcccctt ggactttccg
     1381 acccagctcc cttccagggc tcagcgctca cggtccctac cccagcccaa gctcagcacc
     1441 caactaccca gctggcttct ggcaccaccc tcacaccacc agcgccgccg tcccttcctc
     1501 agcggggatg aggaccccaa ggcttccaca ctacgggttg tggtctttgg ctctgaccgg
     1561 atctcaggga aggtggcccg ggcctatagc aagctcaggc ggctggagaa cagtcacccg
     1621 atcctcaccc ggttcttcaa gcttcagttc ttctacgtac ctgtgaagag aagccacgga
     1681 gccagctcta gtgcctgcct atcctctctg aaccaggcat ctccactcct tccagactcc
     1741 ttgaagcacc ccagccctgc agaccttggc aaggccccat gggaggacag taccaatgac
     1801 atctctcact acctcggtat gcttgaccct tggtatgaac gcaatgtgtt gggcctcatg
     1861 catctgcctc ctgaagtcct gtgtcagcag tccctcaagg cagaatctcg gcccctggag
     1921 ggctcggcca cccagctgcc catcctggcc gatatgttac tctactactg ccgctttgca
     1981 gcccgcccag tgttgctgca ggtttatcag acagagctga ccttcgtcac cggggagaag
     2041 accacggaga tctttatcca gtctctggag ctgggtcact ctgcgaccac tcgtgctatc
     2101 aaggcttcag gtccgggaag caaaaggctg ggcattggcg atgaccggga ggccgtccct
     2161 ctaacactac agattattta cagcaaggga gccatcagtg ggcgaagccg ctggagcaac
     2221 ctagagaagg tctgcacctc tgttaacctc agcaaggcct gccagaagcc ggaggaacta
     2281 gattccagca tggaggcgct gacgctaacc ctgacagaag tggtgaagag gcagaaccct
     2341 aaatccaaaa agggctttaa ccagatcagt acatcctaca tcaaagtgga caaggtgcag
     2401 atcatcagct ccagcagctg cccctttgct gtgtgtctag accaggatga gaggaagatc
     2461 ctgcagagtg tggtcaggtg tgaagtgtca ccctgctaca agccagagaa gagcagcctg
     2521 ccacctgagg ggtccctcag ccaaccagca gaggctgggt ctgacctgtg ctcccttctc
     2581 tgccttccca tcatgacttt cagtggtgct ctgccctagt gcacctaggt atgaggctgg
     2641 acagcaaagt gcccagcttc tcctggacca ctcttcaggg cagctgctct ctatggagaa
     2701 ccaaattgcc cccgggttgc atcaggatct ctctgcaggc cctgctatgg accagggacg
     2761 tctggtcaat gatatcttga gcctcagaga gctgatgagg aaacaggcgt tggagagaga
     2821 agggcctgag atgtccagtc ttacagatgc ctctgagaag agggagaggg atgggtgaga
     2881 ggtcccaaag gaaggtgtga ggcttgtctg tggtttaggc ctcctttcca agccctggac
     2941 tgagacccat ctttgacttg tcaaagactc agggtcccta actagaggtc agtttctcta
     3001 aggcacaggt aggagaaaga tgagtgagat t
//
