LOCUS       NM_001371300            6575 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus phosphatidylinositol-4,5-bisphosphate 3-kinase,
            catalytic subunit gamma (Pik3cg), mRNA.
ACCESSION   NM_001371300 XM_006240005
VERSION     NM_001371300.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6575)
  AUTHORS   Yang R and Zeng C.
  TITLE     MiR-182 promotes apoptosis of neural cells in cerebral infarction
            rats by PI3K/AKT signaling pathway
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 69 (12), 139-143 (2023)
   PUBMED   38063104
  REMARK    GeneRIF: MiR-182 promotes apoptosis of neural cells in cerebral
            infarction rats by PI3K/AKT signaling pathway.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6575)
  AUTHORS   Li F and Liu H.
  TITLE     MiR- 211 represses apoptosis of nerve cells in rats with cerebral
            infarction through PI3K/AKT signaling pathway
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 69 (12), 150-155 (2023)
   PUBMED   38063101
  REMARK    GeneRIF: MiR- 211 represses apoptosis of nerve cells in rats with
            cerebral infarction through PI3K/AKT signaling pathway.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6575)
  AUTHORS   Ye K, Li Z, Yin Y, Zhou J, Li D, Gan Y, Peng D, Xiao M, Zhao L, Dai
            Y and Tang Y.
  TITLE     LIPUS-SCs-Exo promotes peripheral nerve regeneration in cavernous
            nerve crush injury-induced ED rats via PI3K/Akt/FoxO signaling
            pathway
  JOURNAL   CNS Neurosci Ther 29 (11), 3239-3258 (2023)
   PUBMED   37157936
  REMARK    GeneRIF: LIPUS-SCs-Exo promotes peripheral nerve regeneration in
            cavernous nerve crush injury-induced ED rats via PI3K/Akt/FoxO
            signaling pathway.
REFERENCE   4  (bases 1 to 6575)
  AUTHORS   Lu JM, Zhang ZZ, Ma X, Fang SF and Qin XH.
  TITLE     Repression of microRNA-21 inhibits retinal vascular endothelial
            cell growth and angiogenesis via PTEN dependent-PI3K/Akt/VEGF
            signaling pathway in diabetic retinopathy
  JOURNAL   Exp Eye Res 190, 107886 (2020)
   PUBMED   31759996
REFERENCE   5  (bases 1 to 6575)
  AUTHORS   Cavalcanti-Neto MP, Prado RQ, Pineros AR, Sergio CA, Bertolini TB,
            Gembre AF, Ramos SG and Bonato VL.
  TITLE     Improvement of the resistance against early Mycobacterium
            tuberculosis-infection in the absence of PI3Kgamma enzyme is
            associated with increase of CD4+IL-17+ cells and neutrophils
  JOURNAL   Tuberculosis (Edinb) 113, 1-9 (2018)
   PUBMED   30514491
REFERENCE   6  (bases 1 to 6575)
  AUTHORS   Kaplan-Albuquerque N, Garat C, Desseva C, Jones PL and Nemenoff RA.
  TITLE     Platelet-derived growth factor-BB-mediated activation of Akt
            suppresses smooth muscle-specific gene expression through
            inhibition of mitogen-activated protein kinase and redistribution
            of serum response factor
  JOURNAL   J Biol Chem 278 (41), 39830-39838 (2003)
   PUBMED   12882977
REFERENCE   7  (bases 1 to 6575)
  AUTHORS   Brock C, Schaefer M, Reusch HP, Czupalla C, Michalke M, Spicher K,
            Schultz G and Nurnberg B.
  TITLE     Roles of G beta gamma in membrane recruitment and activation of
            p110 gamma/p101 phosphoinositide 3-kinase gamma
  JOURNAL   J Cell Biol 160 (1), 89-99 (2003)
   PUBMED   12507995
REFERENCE   8  (bases 1 to 6575)
  AUTHORS   Yum HK, Arcaroli J, Kupfner J, Shenkar R, Penninger JM, Sasaki T,
            Yang KY, Park JS and Abraham E.
  TITLE     Involvement of phosphoinositide 3-kinases in neutrophil activation
            and the development of acute lung injury
  JOURNAL   J Immunol 167 (11), 6601-6608 (2001)
   PUBMED   11714830
REFERENCE   9  (bases 1 to 6575)
  AUTHORS   Gu C and Park S.
  TITLE     The EphA8 receptor regulates integrin activity through p110gamma
            phosphatidylinositol-3 kinase in a tyrosine kinase
            activity-independent manner
  JOURNAL   Mol Cell Biol 21 (14), 4579-4597 (2001)
   PUBMED   11416136
REFERENCE   10 (bases 1 to 6575)
  AUTHORS   Bony C, Roche S, Shuichi U, Sasaki T, Crackower MA, Penninger J,
            Mano H and Puceat M.
  TITLE     A specific role of phosphatidylinositol 3-kinase gamma. A
            regulation of autonomic Ca(2)+ oscillations in cardiac cells
  JOURNAL   J Cell Biol 152 (4), 717-728 (2001)
   PUBMED   11266463
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000164.1.
            
            [WARNING] On Apr 3, 2024 this sequence was replaced by
            NM_001371300.3.
            
            On Feb 10, 2021 this sequence version replaced NM_001371300.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5756307, SAMEA5760383
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-165               JACYVU010000164.1  25090042-25090206   c
            166-2172            JACYVU010000164.1  25085380-25087386   c
            2173-2238           JACYVU010000164.1  25082070-25082135   c
            2239-2464           JACYVU010000164.1  25081731-25081956   c
            2465-2568           JACYVU010000164.1  25080251-25080354   c
            2569-2715           JACYVU010000164.1  25078644-25078790   c
            2716-2806           JACYVU010000164.1  25077052-25077142   c
            2807-2937           JACYVU010000164.1  25076144-25076274   c
            2938-3049           JACYVU010000164.1  25075080-25075191   c
            3050-3207           JACYVU010000164.1  25072853-25073010   c
            3208-6575           JACYVU010000164.1  25055027-25058394   c
FEATURES             Location/Qualifiers
     source          1..6575
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q16"
     gene            1..6575
                     /gene="Pik3cg"
                     /gene_synonym="Pi3k"
                     /note="phosphatidylinositol-4,5-bisphosphate 3-kinase,
                     catalytic subunit gamma"
                     /db_xref="GeneID:298947"
                     /db_xref="RGD:1306468"
     exon            1..165
                     /gene="Pik3cg"
                     /gene_synonym="Pi3k"
                     /inference="alignment:Splign:2.1.0"
     exon            166..2172
                     /gene="Pik3cg"
                     /gene_synonym="Pi3k"
                     /inference="alignment:Splign:2.1.0"
     CDS             178..3486
                     /gene="Pik3cg"
                     /gene_synonym="Pi3k"
                     /EC_number="2.7.1.153"
                     /note="phosphoinositide-3-kinase, catalytic, gamma
                     polypeptide"
                     /codon_start=1
                     /product="phosphatidylinositol 4,5-bisphosphate 3-kinase
                     catalytic subunit gamma isoform"
                     /protein_id="NP_001358229.1"
                     /db_xref="GeneID:298947"
                     /db_xref="RGD:1306468"
                     /translation="MELENYEQPVVLREDNLRRRRRMKPRSAAGSLSSMELIPIEFVL
                     PTSQRISKTPETALLHVAGHGNVEQMKAQVWLRALETSVAAEFYHRLGPDQFLLLYQK
                     KGQWYEIYDRYQVVQTLDCLRYWKMMHKSPGQIHVVQRHVPSEETLAFQKQLTSLIGY
                     DVTDISNVHDDELEFTRRRLVTPRMAEVAGRDAKLYAMHPWVTSKPLPDYLSKKIVNN
                     CIFIVIHRGTTSQTIKVSADDTPDTILQSFFTKMAKKKSLMNIPESQSEQDFVLRVCG
                     RDEYLVGETPLKNFQWVRQCLKNGEEIHLVLDTPPDPALDEVRNEEWPLVDDCTGVTG
                     YHEQLTIHGKDHESVFTVSLWDCDRKFRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQ
                     VLCQRRTSPKLFTEEVLWNVWLEFGIKIKDLPKGALLNLQIYCCKTPSLSSKASVETP
                     GSESKGKAQLLYYVNLLLIDHRFLLRHGGYVLHMWQISGKAEEQGSFNADKLTSATNP
                     DKENSMSISILLDNYCHPIALPKHRPTPDPEGDRVRAEMPNQLRKQLEAIIATDPLNP
                     LTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQQEIVAKTYQLLARREIWDQSALDV
                     GLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLL
                     KRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRGCGKAMLQDFTQQVHVIE
                     MLQKVTIDIKSLSAEKYDVSSQVISQLKQKLESLQNSSLPESFRVPYDPGLKAGTLVI
                     EKCKVMASKKKPLWLEFKRADPTVLSNETIGIIFKHGDDLRQDMLILQILRIMESIWE
                     AESLDLCLLPYGCISTGDKIGMIEIVKDATTIAQIQQSTVGNTGAFKDEVLNHWLKEK
                     CPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNLFHIDFGHILGNY
                     KSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDVCVRAYLALRHHTNLLIIL
                     FSMMLMTGMPQLTSKEDIEYIRDALMVGRSEEDAKKYFLDQIEVCRDKGWTVQFNWFL
                     HLVLGIKQGEKHSA"
     exon            2173..2238
                     /gene="Pik3cg"
                     /gene_synonym="Pi3k"
                     /inference="alignment:Splign:2.1.0"
     exon            2239..2464
                     /gene="Pik3cg"
                     /gene_synonym="Pi3k"
                     /inference="alignment:Splign:2.1.0"
     exon            2465..2568
                     /gene="Pik3cg"
                     /gene_synonym="Pi3k"
                     /inference="alignment:Splign:2.1.0"
     exon            2569..2715
                     /gene="Pik3cg"
                     /gene_synonym="Pi3k"
                     /inference="alignment:Splign:2.1.0"
     exon            2716..2806
                     /gene="Pik3cg"
                     /gene_synonym="Pi3k"
                     /inference="alignment:Splign:2.1.0"
     exon            2807..2937
                     /gene="Pik3cg"
                     /gene_synonym="Pi3k"
                     /inference="alignment:Splign:2.1.0"
     exon            2938..3049
                     /gene="Pik3cg"
                     /gene_synonym="Pi3k"
                     /inference="alignment:Splign:2.1.0"
     exon            3050..3207
                     /gene="Pik3cg"
                     /gene_synonym="Pi3k"
                     /inference="alignment:Splign:2.1.0"
     exon            3208..6575
                     /gene="Pik3cg"
                     /gene_synonym="Pi3k"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acttccttcc tggtaactgc aacacttcct ctgcatctgg atatgaaggg agccccagaa
       61 aagcagaaga gtctcgagca gtggcccggg taggtttgaa ttcgttttgt tttcatccag
      121 taaacaaatg acccttcctc agcgtcacct ccagtgctgt gtcaggtcac ctagggcatg
      181 gagctggaga actatgaaca acctgtggtt ctgagagagg acaacctccg caggcgccgg
      241 aggatgaagc cacgcagcgc agcaggcagc ctgtcttcca tggagctcat ccccattgag
      301 ttcgtactgc ccaccagcca gcgcatcagc aagacaccgg aaacggccct gctgcatgtg
      361 gctggccacg gcaatgtgga gcagatgaaa gctcaggtgt ggttacgcgc actggagacc
      421 agtgtggctg cggaattcta ccaccgatta ggtccggacc aattcctcct cctctaccag
      481 aagaagggac agtggtatga gatctacgat aggtaccaag tggtgcagac cctagactgc
      541 ctacgttact ggaagatgat gcacaagagc cccggccaga tccacgtggt acagcgacat
      601 gtaccttctg aggagaccct ggctttccag aagcagctca cctccctgat tggctacgac
      661 gtcactgaca tcagcaacgt gcacgatgat gagctagaat tcactcgccg ccgtctggtt
      721 acgccccgca tggctgaagt ggctggccgg gatgccaaac tctatgccat gcacccttgg
      781 gtgacctcca aacctcttcc agactacctg tcaaaaaaaa ttgtcaacaa ttgcattttc
      841 attgtcatcc atcgtggtac caccagtcaa accatcaagg tctccgcaga tgatactcct
      901 gacaccatcc ttcagagctt cttcaccaag atggccaaga agaagtccct aatgaatatc
      961 ccagaaagtc aaagtgagca ggattttgtg ctgcgggtct gtggccgtga tgagtaccta
     1021 gtaggtgaaa cgcccctcaa aaatttccag tgggtgaggc agtgcctcaa gaacggagag
     1081 gaaatacacc tggtgctcga cacgcctcca gacccggccc tagatgaggt gaggaacgaa
     1141 gaatggccgc tggtggatga ctgcactgga gtcaccggct accatgagca gctgaccatc
     1201 catggcaagg accacgagag cgttttcaca gtgtctttgt gggactgtga ccgaaagttc
     1261 agggtcaaga tcagaggcat tgatatccct gtcttgcctc ggaacaccga cctcactgtt
     1321 tttgtggaag caaatatcca gcatgggcaa caagtcctct gccaaaggag aaccagccct
     1381 aagctcttca cagaagaggt gctctggaat gtgtggctgg agtttggcat taaaatcaaa
     1441 gacttgccca aaggggccct actgaaccta cagatctact gctgcaaaac cccatcactg
     1501 tccagtaagg cttccgtaga gacgccaggc tccgagtcca agggcaaagc ccagctcctc
     1561 tattacgtga acttgctgtt gatagaccac cgcttcctcc tccgccatgg gggctacgtg
     1621 ctccacatgt ggcagatatc tgggaaggca gaggaacagg gcagcttcaa tgccgacaag
     1681 ctcacctccg caaccaatcc tgacaaggag aactcaatgt ccatttccat cttgctggac
     1741 aactactgtc accccattgc tttgcctaag caccggccta ctccggaccc agaaggagac
     1801 agagttcgag ctgaaatgcc caatcagctt cgaaagcaat tggaggcaat catagccaca
     1861 gatccactta accccctcac agcagaggac aaagaattgc tctggcattt tagatatgaa
     1921 agcctgaagc atccaaaggc ataccctaaa ctattcagct cagtaaagtg gggacagcaa
     1981 gaaattgttg ccaaaacata ccagctatta gccagaaggg agatctggga tcaaagtgct
     2041 ttggatgttg gcttaaccat gcaactcctg gactgcaact tttcagatga aaacgtaagg
     2101 gccattgcag ttcagaaact ggagagcttg gaggacgatg acgttttaca ttaccttctc
     2161 cagctggtgc aggctgtgaa atttgaacca taccatgaca gtgcgctggc cagattcttg
     2221 ctgaagcgtg gcttgagaaa caagagaatt ggtcacttct tattctggtt cttgcgaagt
     2281 gagatagccc agtccagaca ctatcagcag aggttcgctg tgatcctgga agcgtacctg
     2341 cgcggctgtg gcaaggccat gctacaggac ttcacgcagc aggtccacgt gattgagatg
     2401 ttacagaaag tcaccattga tatcaaatca ctctcggctg agaagtatga tgtcagttcc
     2461 caagttattt cacagcttaa gcaaaagctt gaaagcctgc agaattccag tcttcctgag
     2521 agctttagag ttccctatga tcctggactg aaagcaggta ccctggtgat tgagaagtgt
     2581 aaagtgatgg cctccaagaa gaagcccctg tggcttgagt ttaaacgtgc cgatcctaca
     2641 gtcctatcca atgaaaccat tgggatcatc tttaaacatg gcgacgatct acgccaagac
     2701 atgttgatct tacagattct acgcatcatg gagtccattt gggaggctga atctctggac
     2761 ctgtgccttc tgccttacgg ttgcatctca actggtgaca aaatagggat gatagagatt
     2821 gtgaaggacg ccacgacgat tgctcaaatt cagcagagca cggtgggtaa cacgggggca
     2881 ttcaaagatg aagtcctgaa tcactggctc aaggaaaaat gccctattga agaaaagttt
     2941 caggcagcag tggaaaggtt cgtttactcc tgtgcaggct actgtgtggc cacatttgtt
     3001 cttgggatag gtgacaggca caacgacaac atcatgatct cagagacagg aaacctattt
     3061 cacatagact ttggacacat tcttggcaat tacaagagtt tcctgggcat caataaagag
     3121 agagtacctt ttgtcctaac cccggacttc ttgtttgtga tgggaacttc gggcaaaaag
     3181 acaagtccac acttccagaa attccaggat gtctgcgtta gggcttacct agctcttcgc
     3241 caccacacaa acctgctgat catcctgttc tccatgatgc tgatgacagg aatgccgcag
     3301 ctgacaagca aagaggacat tgaatacatc cgggatgccc tcatggtggg gagaagcgag
     3361 gaggacgcca agaagtattt ccttgatcag attgaagtct gcagggacaa aggatggact
     3421 gtgcagttta actggttcct ccatcttgtt cttggcatca agcaaggaga gaaacactcc
     3481 gcttgatatt tggtgctaga gcccaaagca atttagtgtt ctaaagcttt caaaccagca
     3541 tgtcagtcat cagggttaca tttagaatgc aataggactc tctgaacact gcacttcaga
     3601 aatacagctc tttccccagc tgaactcttc acgagaggaa aacatgttgg cattactgat
     3661 ggcttggtta attaatattc agtgtaaggt ttctctgctg cccccccccc ccccgcctca
     3721 gtctccatga tgctgaacaa tattcgaact ttaaatggct tggtatgcct gatgatcttg
     3781 tattgaataa ctctgaaaat cctttagtta caataattgg caatagctgt tgtcacatgt
     3841 gttcaccatg tcttttggtt gtgttcttcg agctcttggc agaaaagggt acaagcattg
     3901 ctaagctctg ctgcattctt cacaggatgt ttccgagcat cccctccgtg cccaaacatg
     3961 tcggtgatgt gctagaagca aagagtgcaa gttagctttt agagtaccag aataccgtca
     4021 gcagtttgtc tcctagtgtg ccactgagat ggagacacgg aacacagact ctgagcctga
     4081 accttgaccc tccccagctg ctgtaactca agggttatgg atatgaaaag tggaggtaag
     4141 gcctttgacc aagagtgaat aacctaacac ggccaccgtc tcctgcacag acacaggagg
     4201 tcactaactg gacccttgga tgcctacaaa tgacatcttt ccctcttgct ctcccctccc
     4261 ccgccttccc ctgcctcacc accttgcctc acctggactt gtggaacctt caaagacagc
     4321 tgaaaatgac tcgaaaaaga aagtccactg taggctcatg agatacttat ttgtggagct
     4381 gcttcctgga tttttaaaaa gtatattatt aaaagaagag ttccagacaa tattagtttc
     4441 taaatgcttt aatttcactt tttaaatcta aaatttttct ttatttgtta atagaggata
     4501 cctgctatca aatgtattct atgcttataa caataccatt tacatattca ttttttagct
     4561 tacagggctt ttaaattttg aggtacccca gagttcataa agataattga accaattttc
     4621 ctttgaagta ttttttcatt tcttaaatat tatcaatgtt gatccacctt cgagagagat
     4681 cagtaaatta tttaatcaaa catctttagc tatcattaat ttgataaaaa gaactatgtc
     4741 aaagatgtcc atatttagat ataatcaggt ataactcttt ctgacaattt ttaaatggtc
     4801 aaaatagacg ctttaattag atggcgccca accttccctt tgtgtctaca gaagccaagt
     4861 agcacctaat tctgctgcaa ataagaacca tcagggacag ttttaacaca cccttgcatt
     4921 ttaaaatcac cccactttca gattataatt tcatttagtg tgaaatgagc ctgggaagtt
     4981 ttcaaagtac tcggctaaat ctcttatcca tgcaggggaa ggagccttat ttggtccggg
     5041 atggtacagg tagtccttcc cccctgctca caagaccgtc cctagctcat agctatctac
     5101 aaaaaaactc ctcatccctg gcaagtaacc attctaaaat catgctgtct cctgtacagg
     5161 ccctgccctg tgctgaaatt gtgtttctct ctatgagtgt aagttaggta cttcatggca
     5221 tttctggaac gtaactccta ctgatctaag aacaggaaga gtaatgactt ctaactccaa
     5281 aagggtagca tgcttaagcc tgtaaagaac catacacaga ctttgccttt catctgaatt
     5341 gctggaatga tgatctggat gataaaacaa ttacggagta gatctatatt tagcttccga
     5401 caccacatgc atacatatta gctctttaaa tgagccagcc tttccttaaa gctgaactac
     5461 atgacgacac atactgagtt tcattcttcc attttcaaga taatgtactt tcaactccat
     5521 agaccagcat atcaacaaaa atcacctgca cacatgcttg ctacctcgcc gttcctgtga
     5581 atgatacatt ccggtgatct ctataccttt gaaaatgttc tagacctagg gtcctcctgc
     5641 cactgggtaa ataccagtat ctctaccttc agtgctgagt gaagaaaaca cacatcacag
     5701 gtcagatggg tcaggtcaaa gcaatttatg tgtatctaag actgcccccc ccaaaaaaag
     5761 acacaaagta tccattgtag acttggtcca atatgaccct actggtttgg tgatgctctg
     5821 aaaaatgcag aaagatataa tgagtaaaac atatcaacta ggaaaaaagc tcttgatatc
     5881 aagtacatct ttttcaggag atggtttgtt ttatttttat tagttctttg agaattgtgt
     5941 acaaagtttt gaccacatgc acccatatgc agccactcac ccaacttctc ctagactccc
     6001 acccccttcc ttacccaccc aattgtgtcc tctccctttt ttttcttttc attcatcaat
     6061 ggcaacactc taagagaata cttcttctcc cagcaactgt cagttgccaa tagttcttgg
     6121 ctggggtggg atttcgtatc cacctgtcct ctccctgctg ggacttgatg tggcttcagc
     6181 tttcatggga cttgtcataa ctgctacgag ttcatatgtg cagcttctct gctgtgtccg
     6241 gaggattctg attccttgcc tccattcacc acctctgtct cccggtctct caggtccctc
     6301 cctcttccaa tgatcactga ggcttggaag gagagggaga agattagagg ctccacttaa
     6361 ggctgagtat tccgtaggct cttattctgc accatggcta gtcatgagtc tctgtggtga
     6421 tcgtctactg cgaatagaca ctactctgat ataggccgag agatgtacca atctataggt
     6481 aaaacagtaa gtcgttaagg atcagtatgg gcattctata gcatgatttg gaagctgtta
     6541 gtcctatatt catgataact gattataatg ttaaa
//
