LOCUS       NM_053923               5990 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus phosphatidylinositol-4-phosphate 3-kinase,
            catalytic subunit type 2 gamma (Pik3c2g), mRNA.
ACCESSION   NM_053923
VERSION     NM_053923.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5990)
  AUTHORS   Yu,W., Sun,X., Tang,H., Tao,Y. and Dai,Z.
  TITLE     Inhibition of class II phosphoinositide 3-kinase gamma expression
            by p185(Bcr-Abl) contributes to impaired chemotaxis and aberrant
            homing of leukemic cells
  JOURNAL   Leuk Lymphoma 51 (6), 1098-1107 (2010)
   PUBMED   20536348
REFERENCE   2  (bases 1 to 5990)
  AUTHORS   Berger,K.L., Cooper,J.D., Heaton,N.S., Yoon,R., Oakland,T.E.,
            Jordan,T.X., Mateu,G., Grakoui,A. and Randall,G.
  TITLE     Roles for endocytic trafficking and phosphatidylinositol 4-kinase
            III alpha in hepatitis C virus replication
  JOURNAL   Proc Natl Acad Sci U S A 106 (18), 7577-7582 (2009)
   PUBMED   19376974
REFERENCE   3  (bases 1 to 5990)
  AUTHORS   Daimon,M., Sato,H., Oizumi,T., Toriyama,S., Saito,T., Karasawa,S.,
            Jimbu,Y., Wada,K., Kameda,W., Susa,S., Yamaguchi,H., Emi,M.,
            Muramatsu,M., Kubota,I., Kawata,S. and Kato,T.
  TITLE     Association of the PIK3C2G gene polymorphisms with type 2 DM in a
            Japanese population
  JOURNAL   Biochem Biophys Res Commun 365 (3), 466-471 (2008)
   PUBMED   17991425
REFERENCE   4  (bases 1 to 5990)
  AUTHORS   Carini,R., Grazia De Cesaris,M., Splendore,R., Baldanzi,G.,
            Nitti,M.P., Alchera,E., Filigheddu,N., Domenicotti,C.,
            Pronzato,M.A., Graziani,A. and Albano,E.
  TITLE     Role of phosphatidylinositol 3-kinase in the development of
            hepatocyte preconditioning
  JOURNAL   Gastroenterology 127 (3), 914-923 (2004)
   PUBMED   15362046
  REMARK    GeneRIF: By regulating PKC-/delta-dependent signals, PI3K can play
            a key role in the development of hepatic tolerance to
            hypoxia/reperfusion.
REFERENCE   5  (bases 1 to 5990)
  AUTHORS   Yang,K.Y., Arcaroli,J., Kupfner,J., Pitts,T.M., Park,J.S.,
            Strasshiem,D., Perng,R.P. and Abraham,E.
  TITLE     Involvement of phosphatidylinositol 3-kinase gamma in neutrophil
            apoptosis
  JOURNAL   Cell Signal 15 (2), 225-233 (2003)
   PUBMED   12464394
  REMARK    GeneRIF: PI3-Kgamma directly participates in multiple in vivo
            pathways involved in regulating neutrophil apoptosis.
REFERENCE   6  (bases 1 to 5990)
  AUTHORS   Shanley,L.J., O'Malley,D., Irving,A.J., Ashford,M.L. and Harvey,J.
  TITLE     Leptin inhibits epileptiform-like activity in rat hippocampal
            neurones via PI 3-kinase-driven activation of BK channels
  JOURNAL   J Physiol 545 (3), 933-944 (2002)
   PUBMED   12482897
  REMARK    GeneRIF: Leptin, via PI 3-kinase-driven activation of BK channels,
            elicits novel mechanism for controlling neuronal excitability.
            Novel action of leptin could provide an alternative therapeutic
            target in the management of epilepsy.
REFERENCE   7  (bases 1 to 5990)
  AUTHORS   Ono,F., Nakagawa,T., Saito,S., Owada,Y., Sakagami,H., Goto,K.,
            Suzuki,M., Matsuno,S. and Kondo,H.
  TITLE     A novel class II phosphoinositide 3-kinase predominantly expressed
            in the liver and its enhanced expression during liver regeneration
  JOURNAL   J Biol Chem 273 (13), 7731-7736 (1998)
   PUBMED   9516481
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB009636.1.
            
            [WARNING] On Oct 8, 2024 this sequence was replaced by NM_053923.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB009636.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760400, SAMEA5760476
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..5990
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q44"
     gene            1..5990
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /note="phosphatidylinositol-4-phosphate 3-kinase,
                     catalytic subunit type 2 gamma"
                     /db_xref="GeneID:116720"
                     /db_xref="RGD:620231"
     exon            1..32
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
     exon            33..785
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
     CDS             111..4628
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /EC_number="2.7.1.137"
                     /EC_number="2.7.1.154"
                     /note="phosphatidylinositol-4-phosphate 3-kinase C2
                     domain-containing gamma polypeptide; PI3K-C2gamma;
                     ptdIns-3-kinase C2 gamma; phosphoinositide
                     3-Kinase-C2-gamma; PI3K-C2-gamma; ptdIns-3-kinase C2
                     subunit gamma; phosphatidylinositol 3-kinase, C2 domain
                     containing, gamma polypeptide; phosphatidylinositol
                     4-phosphate 3-kinase C2 domain-containing subunit gamma;
                     phosphoinositide-3-kinase, class 2, gamma polypeptide"
                     /codon_start=1
                     /product="phosphatidylinositol 3-kinase C2
                     domain-containing subunit gamma"
                     /protein_id="NP_446375.1"
                     /db_xref="GeneID:116720"
                     /db_xref="RGD:620231"
                     /translation="MAYNWQTEPNRAEPQEGGHDHQQCHHADQHLSSRQVRLGFDQLV
                     EELSNKTPLPEDEKEGTCFVPDTPNLDSKWQSIYGPHPRHFNEFTSQSPHFSQLPFGK
                     ASAIGFNPAVLPAHQFIHEGASWRNPTRKYHGGEDPRFSALTPSSTGLDKCHQQGQSG
                     TEHCNYYVEPENNVPHHYSPYSMDSIPDSEEKGSGDADLVEPSLVFSKDSFLPRASEN
                     MSVESTEPIGCPLEIVEAPQGSNKSLASFCNNVTKIRGLYHASDTNSNSGKIWAITTA
                     YPSRLFADTQFRVKISTDNSAQLLLLKPPANYLVKDLIAEILLLCANEQLSPKEYLLS
                     ICGSEEFLQTDHCLGSHKIFQKSKSVIQLHLQRSRDTPGKLSRKRDDDRSRVHLNQLL
                     EFTHIWKISRQCLSTVMKSYNLHVEHLLKTQEDVEEKPLSSMFSCGRHPPQPHGNDII
                     EDVRNICSVLGCIETKQVSDAVKELTLILQRPSQNFHQNSETSKKGFIENVTSELSRS
                     LHQLVDVYCSSFCTDFRPARAPGGVSRDHAGLHSHLSFTVCSLHNVPETWAHSYKAFS
                     FSCWLTYAGKKLCQVKSCRSLPVTKSFSFSVNWNEIINFPLEIKSLPRESMLVIKLFG
                     IDSATHSANLLAWTCLPLFPKEKSPLGSRLLSMTLQSEPPIEMMAPGVWDGSQPTPLT
                     LQIDFPAATWEYVKPETEENRTDHQEPPRECLKHIARLSQKQPPLLLSVEKRRYLWFY
                     RFYCNNENSSLPLVLGSAPGWDEGTVSEMHAVLRRWTFSHPLEALGLLTSRFPDQDIR
                     EVAVQQLDNFLTDELLDCLPQLVQAVKFEWSLESPLVELLLHRSLQSIRVAHRLFWLL
                     RDAQGEDYFKSWYQELLAALQFCAGEALIEELSKEQKLVKLLGDIGEKVKSAGDAQRK
                     DVLKKEIGSLEEFFKDIKTCHLPLNPALCVKGIDRDACSYFTSNALPLKITFINANPM
                     GKNISVIFKAGDDLRQDMLVLQIIQVMDNVWLQEGLDMQMIIYGCLATGKAQGFIEMV
                     PDAVTLAKIHLHSGLIGPLKENTIKKWFSQHNHLKEDYEKALRNFFYSCAGWCVVTFI
                     LGVCDRHNDNIMLTKSGHMFHIDFGKFLGHAQTFGGIKRDRAPFIFTSEMEYFITEGG
                     KNTQHFQDFVELCCRAYNIVRKHSQLLLSLLEMMLHAGLPELRGIEDLKYVHDNLRPQ
                     DTDLEATSHFTTKIKQSLECFPVKLNNLIHTLAQMPAFSLARPAPQTPPQECCVLNKT
                     RTIQRVTILGFSKTHSNLYLIEVTRSDNRKNLAKKSFEQFYRLHSQIQKQFPLLTLPE
                     FPHWWHLPFTDSHHERIRDLSHYVEQVLHGSYEVANSDCVLSFFLSEHIQQTLEDSPF
                     VDPGDHSPDKSPQVQLLMTYEDTKLTILVKHLKNIHLPDGSAPSAHVEIYLLPHPSEV
                     RRKKTKCVPKCTDPTYNEIVVYDDVSGLQGHVLMLIVKSKTVFVGAVNIQLCSVPLNE
                     EKWYPLGNSII"
     exon            786..868
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
     exon            869..1026
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
     exon            1027..1141
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
     exon            1142..1244
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
     exon            1245..1315
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
     exon            1316..1379
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
     exon            1380..1439
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
     exon            1440..1562
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
     exon            1563..1596
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
     exon            1597..1792
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
     exon            1793..1915
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
     exon            1916..2047
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
     exon            2048..2162
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
     exon            2163..2293
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
     exon            2294..2482
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
     exon            2483..2576
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
     exon            2577..2671
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
     exon            2672..2852
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
     exon            2853..2960
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
     exon            2961..3053
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
     exon            3054..3183
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
     exon            3184..3320
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
     exon            3321..3490
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
     exon            3491..3647
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
     exon            3648..3757
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
     exon            3758..3947
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
     exon            3948..4069
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
     exon            4070..4178
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
     exon            4179..4254
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
     exon            4255..4349
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
     exon            4350..4475
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
     exon            4476..5957
                     /gene="Pik3c2g"
                     /gene_synonym="LRRG00132"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaggaagcaa agaccgggca aaacacatga aggaaaattt ggaacttctt ttataatatc
       61 aacaagacat ttggggccaa ataaatcctc tccgttacac aaaaccaaaa atggcataca
      121 attggcaaac agagccaaac cgtgctgaac cacaggaagg tggacatgat caccagcagt
      181 gtcaccatgc agaccagcac ctttcttcca ggcaagtcag gttgggtttt gatcagcttg
      241 tggaagagct cagtaacaaa actccactgc ctgaggatga aaaagaaggc acgtgttttg
      301 taccagatac accaaacttg gattcaaaat ggcaatccat atatggaccc cacccaaggc
      361 acttcaatga attcacttct cagagtcccc acttctccca gcttcctttt ggaaaagcat
      421 cagccattgg ttttaatcct gctgtattac ctgcacatca gttcattcat gagggagcct
      481 cctggagaaa tcccacaaga aaatatcatg gtggtgagga tcccaggttc agtgctctaa
      541 ctccgtcatc cactggcttg gataaatgtc atcaacaagg acaatcaggg accgaacatt
      601 gtaactatta tgtggaacct gaaaacaatg ttccccatca ttattcaccc tactcaatgg
      661 actccatacc cgatagtgag gaaaaaggaa gtggagatgc ggatcttgta gaaccttctc
      721 tggtgttctc taaagactcc tttctaccca gggcatcgga gaacatgtca gtggaaagca
      781 cagagcccat tggttgcccc cttgaaatag ttgaagcacc ccaagggagt aacaagagcc
      841 tcgcctcctt ttgcaacaat gtaacaaaaa taagaggact atatcatgca agtgacacta
      901 attccaattc cggaaagatc tgggccatca ccacagccta tccatctcgg ctcttcgctg
      961 acacccagtt cagagttaaa atttccactg ataactcggc acaacttctt cttcttaagc
     1021 cacccgctaa ttatcttgtc aaagacctaa ttgccgaaat tctactttta tgtgcaaatg
     1081 agcagctttc ccccaaagag tatcttctaa gtatatgcgg ttctgaggaa tttttacaga
     1141 cggatcactg tctagggagc cacaaaatat ttcagaaaag taaatctgtc attcaactcc
     1201 atctccagag aagcagggac actccaggaa aattatcccg gaagagggat gatgaccgca
     1261 gtcgggtcca tctgaaccaa cttctagaat ttacacatat ttggaaaata tccagacaat
     1321 gcctctccac agtaatgaaa agctacaacc tccatgtcga gcacctgttg aaaacccagg
     1381 aagatgtgga ggagaaacct ctgtcatcca tgttttcctg tggccgacac cctcctcagc
     1441 cacatgggaa tgacattatt gaagatgtta gaaacatatg cagtgttctg gggtgtattg
     1501 aaaccaaaca agtttcagat gcagtaaaag aactaactct aattctgcag agaccatcac
     1561 agaattttca tcagaattca gagacttcaa aaaaaggctt catagagaac gtgacatcgg
     1621 aactgtcgag gtccctccat cagctggttg acgtgtactg cagtagcttt tgtacagatt
     1681 tccggcctgc gcgcgcacct ggaggcgtct cccgcgacca cgctgggctc cactcccacc
     1741 tgagcttcac ggtgtgttcc ctgcacaatg ttccagaaac ttgggcacac agctacaaag
     1801 cattttcatt ttcctgctgg ctcacatatg ctgggaagaa gctgtgccaa gtgaaaagct
     1861 gcagatccct gccagtcaca aagtcattct ctttttcggt gaactggaat gaaataatca
     1921 attttcctct tgagataaag tcacttccaa gagaatccat gctcgttata aagctgtttg
     1981 ggattgacag tgccacccac agcgcaaatc tgctggcctg gacctgcctt ccactatttc
     2041 caaaagaaaa gtctccgctg gggtctaggc ttctcagcat gacactacag agtgagcctc
     2101 ctatagaaat gatggctcca ggagtatggg atgggagcca gcctacccca ctgaccctgc
     2161 agatagattt tccagctgcc acgtgggagt acgtgaaacc tgagactgaa gagaacagaa
     2221 ctgaccacca agagcctcca agagagtgtt taaaacacat cgccagactc tcccaaaagc
     2281 agcctccctt gctactttct gtggaaaaga ggagatattt gtggttttat cgtttctact
     2341 gcaacaatga gaactcctct ctccctctgg tcttgggcag cgcccctggt tgggatgaag
     2401 ggacagtttc ggaaatgcat gccgtcttga gaaggtggac attttcccat ccgttggaag
     2461 ctcttggcct tttgacttcc aggtttccag accaagacat tcgtgaagtt gccgttcaac
     2521 agttagacaa cttcttgacc gatgagctgc tggactgcct cccacagcta gttcaggctg
     2581 tcaagtttga gtggagtctc gaaagtccct tggtggaact cctgcttcat cgatccttgc
     2641 aaagcatccg agtggctcac cgcctgttct ggctgctgcg ggatgcacaa ggtgaagact
     2701 actttaaaag ctggtaccag gagcttttgg ccgctctcca gttctgtgca ggagaagccc
     2761 tgatcgaaga gctttccaaa gagcagaaac ttgtcaaact cctgggtgat attggagaaa
     2821 aagtgaagtc ggctggcgat gctcagagaa aggatgtgct aaagaaggag attggcagtc
     2881 tagaagaatt ctttaaagat ataaagactt gccatcttcc tctgaacccg gccctgtgcg
     2941 taaaaggaat tgatcgggat gcatgttcat atttcacatc taatgccttg ccattgaaga
     3001 tcactttcat caatgctaat ccaatgggca aaaatatcag tgttattttt aaggccggcg
     3061 acgatcttcg gcaggatatg cttgttctgc agattattca agtgatggac aacgtttggc
     3121 ttcaggaggg cctcgatatg caaatgatca tttatggatg tctagccaca ggaaaggctc
     3181 aaggattcat agagatggtg cctgatgctg taacgcttgc caagatccat ctgcactctg
     3241 ggctgatagg acccctgaaa gaaaacacca tcaagaagtg gttcagtcag cacaaccact
     3301 taaaggaaga ttatgaaaag gccttgagga acttttttta ctcttgtgct ggctggtgtg
     3361 tggtgacatt catcttggga gtctgtgacc gacataatga caatatcatg ctgacaaagt
     3421 caggccacat gtttcatatt gactttggaa aattcttggg tcacgcacaa acatttggcg
     3481 gtataaaaag ggaccgagcg cctttcattt ttacttcaga gatggagtac tttattacgg
     3541 agggtgggaa aaacacacag cattttcaag acttcgtgga actctgctgc agagcctaca
     3601 acattgtgag gaagcacagc caactgctcc tgagccttct agaaatgatg ctgcatgccg
     3661 ggcttcctga gctgaggggg attgaagacc tgaaatacgt acacgacaat ctccggccac
     3721 aagacacaga cctggaagcc acaagtcatt ttaccacgaa gataaagcag agtctggagt
     3781 gcttcccagt taaactgaat aacctgatcc acacgcttgc acagatgcca gccttcagcc
     3841 ttgccagacc tgcccctcag actcctcccc aggagtgctg cgtcctgaat aaaaccagga
     3901 caattcagag agtcacaatt ttagggttca gcaagacaca cagcaacctg tacctgatcg
     3961 aggtgacacg cagcgacaac aggaaaaacc tggccaaaaa gtccttcgag cagttttaca
     4021 gacttcacag ccagattcag aagcagttcc ccttgttgac tctcccagag tttcctcact
     4081 ggtggcatct acctttcaca gactcgcacc atgagagaat ccgagatctg agtcactacg
     4141 tggaacaggt gctgcacgga tcttacgaag tcgcaaacag tgattgtgta ctcagttttt
     4201 ttctctctga acatatacaa cagacccttg aagactctcc atttgtggac ccaggtgacc
     4261 attctccaga caagagcccc caggtgcagt tgctgatgac ctatgaggac acaaagctca
     4321 ccatcctagt gaaacacttg aaaaacatcc atctcccaga tggctcagcg cccagcgcac
     4381 atgttgaaat ttatcttctg ccacatccca gtgaagttcg caggaagaaa acaaagtgcg
     4441 ttccaaaatg cactgaccca acttacaatg aaattgtggt atatgatgac gtctcaggac
     4501 ttcagggaca tgttttaatg ctcattgtga agagcaaaac tgtatttgtg ggagcggtta
     4561 acattcagct ctgcagtgtt cccctcaatg aagaaaagtg gtacccatta gggaacagta
     4621 tcatctgacc aatgccatga atgtatgcat tattgattaa gtacttgtgt gttttcagct
     4681 tccatttccc ctatagcata cacaaggcat ctttcttgcg gaagatggct tggagcagtg
     4741 gttctcactc agcgtcccta acactgcgac cctttaatac aattcctggt gattgtagtg
     4801 acccaaacca caaaattatt ttagttgcta tttcacaact gtaattttga cacggttatg
     4861 aattgcaatg tatatatctg atctacagga tacctactat tcgacccctg tgataaaagg
     4921 gtcattggac aatcccaaag ggtcatgact catgggttga gaaccacagg cttagagtgg
     4981 tcacagaaga agcagatcaa aatcagtctt ttgtagctct ttcttctcta ccttctcctt
     5041 attttcttat catattttct ccttggaata ttcatcatgg aaaatcccat atgcaaagtc
     5101 atgaaagaat gattcattta atatgcattt ttgaatcaaa ctaagttcat gtcttgcctt
     5161 aattgcttgt tgaggtcaaa attatacttt tagggtgttt tctaaagcta ggagaagctc
     5221 atgtaagggt taagaatatt tgcaatatat ttcaaaagtt aaatatgtgt acaagccaca
     5281 tatctagtca tgattgaatt tattgagaga attggtgatc tccaaccatg tgctataatt
     5341 tttctatcaa aaaaaaatcc ctaagatttt tctattgcat agattttttt tctttaagaa
     5401 tttcatgcat gtatatagtg ctttcgttat tgtagcttct ctctttttta gttgtcccca
     5461 cacccatcaa caactgttct tctctaaaac tcctgtattc ctgtggggag ttttattttt
     5521 aagatgggca tcaaactata tatcccagct gacctagagc ttgctatgtt gaccaggtgg
     5581 gccccaaatc acagtggtcc tcctgcctct gtttcccgac cgctaaggtt ccaggtcatt
     5641 ggatcttgtc tgtaattttt aagttcagtt cttagaattt gatattgatc aatccagtgt
     5701 cattgtgtct tccagcctcg gtcatgttca caccttaaat cttattaatc tccaaaccca
     5761 aaatatccaa cttttaagtt caccatttaa aacgcctctt tgcgtgttaa atactctcac
     5821 tgcacttgaa ccaacacctt gtgttcgcac ggaccagata gatgatctca cagtttgtca
     5881 cctgtgtaac aggcaaaccc agaggacgcc tccaagataa tcaaactgga ggtttcaaaa
     5941 ataaaacatc tgccataaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//
