LOCUS       NM_194461               1509 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus phosphatidylinositol glycan anchor biosynthesis,
            class W (Pigw), mRNA.
ACCESSION   NM_194461
VERSION     NM_194461.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1509)
  AUTHORS   Chiyonobu,T., Inoue,N., Morimoto,M., Kinoshita,T. and Murakami,Y.
  TITLE     Glycosylphosphatidylinositol (GPI) anchor deficiency caused by
            mutations in PIGW is associated with West syndrome and
            hyperphosphatasia with mental retardation syndrome
  JOURNAL   J Med Genet 51 (3), 203-207 (2014)
   PUBMED   24367057
REFERENCE   2  (bases 1 to 1509)
  AUTHORS   Murakami,Y., Siripanyapinyo,U., Hong,Y., Kang,J.Y., Ishihara,S.,
            Nakakuma,H., Maeda,Y. and Kinoshita,T.
  TITLE     PIG-W is critical for inositol acylation but not for flipping of
            glycosylphosphatidylinositol-anchor
  JOURNAL   Mol Biol Cell 14 (10), 4285-4295 (2003)
   PUBMED   14517336
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB097817.1.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1509
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q26"
     gene            1..1509
                     /gene="Pigw"
                     /note="phosphatidylinositol glycan anchor biosynthesis,
                     class W"
                     /db_xref="GeneID:378774"
                     /db_xref="RGD:727962"
     CDS             1..1509
                     /gene="Pigw"
                     /note="PIG-W; phosphatidylinositol glycan, class W"
                     /codon_start=1
                     /product="phosphatidylinositol-glycan biosynthesis class W
                     protein"
                     /protein_id="NP_919443.1"
                     /db_xref="GeneID:378774"
                     /db_xref="RGD:727962"
                     /translation="MSQKQLKEAFVSNLSGTSVLEVTQGLCFPAFCILCRGLLIIFSQ
                     HLCSFLHTWTTQFFMDFVVLIVPLVITLTVLSSFILLENLTVILCGAWLLYQIYHRRT
                     CYAKVPVQKVFASFLKISLESEYNPAITCYRVINSVFTAIAILAVDFPLFPRRFAKTE
                     LYGTGAMDFGVGGFIFGAAMVCPEVRRKYTEGSRFNHLRKSLYSVWPLVFLGMGRLVI
                     IKSIGYQEHSTEYGVHWNFFFTIIVVKLITSLLLIIFPLNKSWIVAISITVLYQLALD
                     FTPLKGIILYGTDGRGTRVGLLNANREGIISTLGYVAIYMAGVQTGFYVFKRRAQVRD
                     WIKATCWVFSVAVGFFISLNIVQVNVEAVSRRMANLAFCLWVVASSLMLLSCLLLSGI
                     VLSFAKFLIKGALVPCSWKLIQSATTNRQSESLIVEAEKNKPSFCLITALNRNQLFFF
                     LLSNVATGLINLTVDTLHTGAFWTLAVLSIYMFANCLVIYVLDLQGKTIKFW"
     exon            1..1509
                     /gene="Pigw"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgtctcaaa agcagctgaa ggaagctttt gtcagtaacc tcagtgggac cagtgttctg
       61 gaagtgaccc agggcctgtg ctttcctgcg ttctgtatcc tgtgtagagg ccttctgatc
      121 attttctcac agcatttgtg ctctttcttg cacacctgga ccacacaatt cttcatggac
      181 tttgttgtct tgatagtccc cctagtgatc actctgactg tattgtcttc ctttatcctc
      241 cttgagaatc tcactgtgat tctctgtggg gcgtggctgt tgtatcagat ataccacagg
      301 aggacttgct atgccaaagt acctgtccag aaagtctttg caagcttctt gaaaatcagc
      361 ctagaatcag agtacaatcc agccatcacc tgttaccggg tcattaacag tgtatttact
      421 gctattgcca ttttggctgt ggatttccca cttttcccta gaagatttgc caaaactgaa
      481 ctttatggga caggagcaat ggattttgga gtaggtggct ttatttttgg ggctgcaatg
      541 gtttgcccag aggttagaag gaaatataca gaagggtcta gatttaatca tcttagaaaa
      601 tcgctgtatt ctgtctggcc attagtcttc ttaggaatgg gaaggttagt cattataaaa
      661 tccataggct accaggaaca ttcaactgag tatggagttc actggaattt tttctttacc
      721 atcatagttg tgaaattaat aacatcactg cttttgatta tttttccttt aaataagtca
      781 tggattgtgg ccatcagcat tactgtgttg taccagcttg cccttgactt tactccactc
      841 aaggggataa ttttgtatgg cactgatggc aggggcacaa gagttggctt attaaatgct
      901 aaccgagagg gaataatttc caccttgggg tatgtggcaa tatacatggc tggtgtacaa
      961 acaggatttt atgtgttcaa gagaagagca caggtcagag actggataaa agctacttgt
     1021 tgggtattct cggtggctgt tggcttcttc atttctctta atatagtgca agtaaacgta
     1081 gaagcagtat ctcgaagaat ggccaattta gccttttgtc tgtgggtggt tgcctccagc
     1141 ctgatgctgc ttagttgtct gttactgagt ggtatcgttt tgagttttgc caaatttcta
     1201 attaaagggg ctctagttcc atgttcttgg aaacttatac agtctgctac tacaaataga
     1261 cagtctgaat ctctaatcgt agaagctgaa aagaacaaac ccagtttttg tttgatcaca
     1321 gctctgaaca gaaaccagtt gttttttttc ttactgtcaa atgtagcaac tggtctgatt
     1381 aacctgacgg tggatacatt acacactggt gccttttgga ccttagctgt gcttagtatt
     1441 tatatgtttg ccaactgctt agttatatat gtacttgact tacaaggtaa aaccataaag
     1501 ttctggtga
//
