LOCUS       NM_001012207            1446 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Rattus norvegicus phosphatidylinositol glycan anchor biosynthesis,
            class C (Pigc), transcript variant 1, mRNA.
ACCESSION   NM_001012207 XM_344167
VERSION     NM_001012207.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1446)
  AUTHORS   Edvardson,S., Murakami,Y., Nguyen,T.T., Shahrour,M., St-Denis,A.,
            Shaag,A., Damseh,N., Le Deist,F., Bryceson,Y., Abu-Libdeh,B.,
            Campeau,P.M., Kinoshita,T. and Elpeleg,O.
  TITLE     Mutations in the phosphatidylinositol glycan C (PIGC) gene are
            associated with epilepsy and intellectual disability
  JOURNAL   J Med Genet 54 (3), 196-201 (2017)
   PUBMED   27694521
REFERENCE   2  (bases 1 to 1446)
  AUTHORS   Watanabe,R., Murakami,Y., Marmor,M.D., Inoue,N., Maeda,Y., Hino,J.,
            Kangawa,K., Julius,M. and Kinoshita,T.
  TITLE     Initial enzyme for glycosylphosphatidylinositol biosynthesis
            requires PIG-P and is regulated by DPM2
  JOURNAL   EMBO J 19 (16), 4402-4411 (2000)
   PUBMED   10944123
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC087080.1.
            
            On Feb 11, 2005 this sequence version replaced XM_344167.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC087080.1, CK599462.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132270, SAMD00132272
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1446
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q22"
     gene            1..1446
                     /gene="Pigc"
                     /note="phosphatidylinositol glycan anchor biosynthesis,
                     class C"
                     /db_xref="GeneID:364032"
                     /db_xref="RGD:1311337"
     exon            1..61
                     /gene="Pigc"
                     /inference="alignment:Splign:2.1.0"
     exon            62..1392
                     /gene="Pigc"
                     /inference="alignment:Splign:2.1.0"
     CDS             223..1116
                     /gene="Pigc"
                     /EC_number="2.4.1.198"
                     /note="PIG-C; phosphatidylinositol-glycan biosynthesis
                     class C protein; phosphatidylinositol glycan, class C"
                     /codon_start=1
                     /product="phosphatidylinositol
                     N-acetylglucosaminyltransferase subunit C"
                     /protein_id="NP_001012207.1"
                     /db_xref="GeneID:364032"
                     /db_xref="RGD:1311337"
                     /translation="MCAQHVADTSEVKWQKVLYERQPFPDNYVDQRFLEELRKNIYAR
                     KYQYWAVVFESSVVIQQLCSVCVFVVIWWYMDEGLLAPQWLFGTGLASSLVGYVLFDL
                     IDGGDGRKKSGRTRWADLKSTLVFITFTYGFSPVLKTLTESVSTDTIYAMSVFMLLGH
                     LIFFDYGANAAIVSSTLSLNMAIFASVCLASRLPRSLHAFIMVTFAIQIFALWPMLQK
                     KLKAYTPRSYVGVTLLFAFSAFGGLLSISGVGAILFALLLFSISCLCPYYLIHLQLFK
                     ENIHGPWDEAEIKEDLSRFLS"
ORIGIN      
        1 ggcctttccg gctgagccaa ggctgggaga ggggcggcgg cgggcagggc aggccggctt
       61 ggcttagcct ggcccgaaga ctttgtaaac aaggaaagtt ctgtatgcta tcagcgtggc
      121 atttctgaga ggtcttaatc tacaacttta tcaagaacta gaatcctgtg ggcatctttg
      181 agggagattg agcccgcctg gatttcagga aaggatgaga taatgtgtgc tcaacatgta
      241 gcggacacct ccgaagtcaa gtggcagaag gttttatatg agcggcagcc attccctgat
      301 aactatgttg accaaaggtt cctggaggag ctccggaaaa acatctatgc ccggaaatac
      361 caatactggg ctgtggtatt tgagtccagt gtggtgatac aacagctgtg cagtgtctgt
      421 gtctttgtag tcatttggtg gtacatggac gagggtcttc tggctcccca gtggcttttt
      481 gggactggac tggcatcgtc cttggttggg tatgtgttat ttgatcttat tgatggaggt
      541 gatggacgga agaagagtgg gcggacccgg tgggccgacc tgaagagtac tctggtcttc
      601 attactttca cgtacggttt ctcaccagtg ctaaagaccc tgacagagtc cgtcagtacg
      661 gacaccatct acgccatgtc cgtttttatg ctgttaggcc atctcatctt ctttgattac
      721 ggtgccaatg ctgctattgt atctagcaca ctgtccttga atatggccat ctttgcttct
      781 gtttgcctgg cctcacgcct cccccggtca ctacatgcct tcatcatggt gacatttgcc
      841 atccagatct ttgcactgtg gcccatgtta cagaagaaac tgaaggcgta taccccaaga
      901 agctatgtcg gggtcaccct gctttttgcc ttttcagctt ttggaggtct tttgtccatt
      961 agtggtgtgg gagccatact ctttgctctt ctgctgtttt ccatttcctg tctctgccct
     1021 tactatctca ttcacctgca gctttttaag gaaaatattc atgggccttg ggatgaggca
     1081 gaaatcaagg aagacttgtc caggttcctt agctaaccta gggacctgca tttcattatt
     1141 aagaaaagtt aaaagactta gaacctaacc agtgtaacat ttaaaggcag ggttccactc
     1201 tcaaagcagc aggctgatct gggtggtaga gctgagatca gaagagttta accaagggtt
     1261 taggggaagg tgtttgccct tcagtttacc ttgtgactta aaaagctttc tggtgctgtt
     1321 atgaattatt gtcctttatt ccctctaaca atgatgtgat gtgggttctg cttattaaaa
     1381 gagtaacatc taaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1441 aaaaaa
//
