LOCUS       NM_001106318            3321 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus p53-induced death domain protein 1 (Pidd1), mRNA.
ACCESSION   NM_001106318 XM_001062274 XM_219485
VERSION     NM_001106318.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3321)
  AUTHORS   Tang,F., Xu,F., Cui,L., Huang,W., Jiang,L., Chen,L., Yan,W., He,W.,
            Shen,C., Huang,H., Lv,J., Zhao,X., Zeng,S., Li,M., Ouyang,Y.,
            Guo,X., Zhong,H. and Zhang,M.
  TITLE     The expression and role of PIDD in retina after optic nerve crush
  JOURNAL   J Mol Histol 51 (1), 89-97 (2020)
   PUBMED   32065357
  REMARK    GeneRIF: The expression and role of PIDD in retina after optic
            nerve crush.
REFERENCE   2  (bases 1 to 3321)
  AUTHORS   Zhang,M., Chen,L., Xu,F., Jiang,L., Yan,W., Kunwar,B., Tang,F.,
            Yang,K., Shen,C., Huang,H., Lv,J., Qin,C., Wu,X., Zeng,S., Li,M.,
            Zhong,S. and Chen,Q.
  TITLE     Involvement of Upregulated P53-Induced Death Domain Protein in
            Retinal Ganglion Cells Apoptosis After Optic Nerve Crush
  JOURNAL   Curr Mol Med 20 (1), 51-59 (2019)
   PUBMED   31533600
  REMARK    GeneRIF: Involvement of Upregulated P53-Induced Death Domain
            Protein in Retinal Ganglion Cells Apoptosis After Optic Nerve
            Crush.
REFERENCE   3  (bases 1 to 3321)
  AUTHORS   Oliver,T.G., Meylan,E., Chang,G.P., Xue,W., Burke,J.R.,
            Humpton,T.J., Hubbard,D., Bhutkar,A. and Jacks,T.
  TITLE     Caspase-2-mediated cleavage of Mdm2 creates a p53-induced positive
            feedback loop
  JOURNAL   Mol Cell 43 (1), 57-71 (2011)
   PUBMED   21726810
REFERENCE   4  (bases 1 to 3321)
  AUTHORS   Tinel,A., Janssens,S., Lippens,S., Cuenin,S., Logette,E.,
            Jaccard,B., Quadroni,M. and Tschopp,J.
  TITLE     Autoproteolysis of PIDD marks the bifurcation between pro-death
            caspase-2 and pro-survival NF-kappaB pathway
  JOURNAL   EMBO J 26 (1), 197-208 (2007)
   PUBMED   17159900
REFERENCE   5  (bases 1 to 3321)
  AUTHORS   Berube,C., Boucher,L.M., Ma,W., Wakeham,A., Salmena,L., Hakem,R.,
            Yeh,W.C., Mak,T.W. and Benchimol,S.
  TITLE     Apoptosis caused by p53-induced protein with death domain (PIDD)
            depends on the death adapter protein RAIDD
  JOURNAL   Proc Natl Acad Sci U S A 102 (40), 14314-14320 (2005)
   PUBMED   16183742
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On or before Jul 8, 2012 this sequence version replaced
            XM_219485.5, XM_001062274.2, NM_001106318.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760383, SAMEA5760386
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-388               JAXUCZ010000001.1  205971213-205971600 c
            389-802             JAXUCZ010000001.1  205970380-205970793 c
            803-1012            JAXUCZ010000001.1  205969885-205970094 c
            1013-1067           JAXUCZ010000001.1  205969747-205969801 c
            1068-1269           JAXUCZ010000001.1  205969444-205969645 c
            1270-1401           JAXUCZ010000001.1  205969235-205969366 c
            1402-1581           JAXUCZ010000001.1  205968950-205969129 c
            1582-1729           JAXUCZ010000001.1  205968730-205968877 c
            1730-1865           JAXUCZ010000001.1  205968503-205968638 c
            1866-2016           JAXUCZ010000001.1  205968276-205968426 c
            2017-2140           JAXUCZ010000001.1  205968065-205968188 c
            2141-2259           JAXUCZ010000001.1  205967866-205967984 c
            2260-2373           JAXUCZ010000001.1  205967667-205967780 c
            2374-2573           JAXUCZ010000001.1  205967367-205967566 c
            2574-3321           JAXUCZ010000001.1  205966392-205967139 c
FEATURES             Location/Qualifiers
     source          1..3321
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q41"
     gene            1..3321
                     /gene="Pidd1"
                     /gene_synonym="Lrdd; Pidd"
                     /note="p53-induced death domain protein 1"
                     /db_xref="GeneID:293625"
                     /db_xref="RGD:1311792"
     exon            1..388
                     /gene="Pidd1"
                     /gene_synonym="Lrdd; Pidd"
                     /inference="alignment:Splign:2.1.0"
     CDS             79..2832
                     /gene="Pidd1"
                     /gene_synonym="Lrdd; Pidd"
                     /note="leucine-rich repeats and death domain containing;
                     p53-induced protein with a death domain-like"
                     /codon_start=1
                     /product="p53-induced death domain-containing protein 1"
                     /protein_id="NP_001099788.2"
                     /db_xref="GeneID:293625"
                     /db_xref="RGD:1311792"
                     /translation="MAAVLEGPKPEETAAAAEDAARPTVEAVASRPGVPILLAGNQLN
                     LDLRPGGCRRLQYLCSQQHTQLLQVEFLRLSTHEDPRLLDDTLAKVPWSLLRLRSLVL
                     KGGQSRGALGACLHGTLTTLPASMRDLACLAHLDLSFNRLETLPTCVLELHSLDALLL
                     SHNCLSELPEALGALPTLTFLTVTHNLLERLPPTLGSLSTLQRLDLSENLLDTIPSEI
                     GDLSSLRELNLASNRLQHLPASLAGLRSLRLLVLHSNLLTSVPPGLAHLPLITRLDLR
                     DNQLRDLPAELLDAPFVRLQGNPLGEASPAPPSPPDISQVPEMPRLFLTSDLDSFLVT
                     PHGCSVTLACGVRLQFPAGATTTPITIHYRLWLPEPGLVSLGPHDFLLSGVLELQPHG
                     VAFQQNVSLWLLFVPPRVRVRRCREVVVRTRSDNIWNDLETHLEEEAPKRRWARCQVP
                     HFSWFLVVLRPVSNTCLLPPEGALLCSSGHPGVKVTFPPGVTEEPRQVSMQVVHMAGL
                     ELRALLEESEAAVSPLLCLSQSGPPSFLQPVTVQLPLPPGVTGFSLDRSHLHLLYRTP
                     LTSTWDDISTQVALEFTHLYARFQVTHFSWYWLWYTTKTCVGGLARKAWERLRLHRVN
                     LIALQRRRDPEQVLLQCLPRSKVDATLSRLLDRYRGPEPSETVEMFEGEKFFAAFERG
                     IDVDADRPDCVDGRICFVFYSHLKNMKEVYITTALDREAQDVRGQVSFYRGSLPMEVP
                     EEAEAARRRKGTDALWMATLPIKLPRLRGAQGSGQGTDFSLMPLNLGDAETGFLTQSN
                     LLSVASRLGSDWPTVALHLGMPYRKLQRIRHEFRDDLDGQIRHMLFSWAESQTGQPGA
                     VGHLVQALEQSDRQDVAEEVRAILELGRHKYQDSIRRTGLAPEDSTLPSTSALQNPES
                     AQA"
     exon            389..802
                     /gene="Pidd1"
                     /gene_synonym="Lrdd; Pidd"
                     /inference="alignment:Splign:2.1.0"
     exon            803..1012
                     /gene="Pidd1"
                     /gene_synonym="Lrdd; Pidd"
                     /inference="alignment:Splign:2.1.0"
     exon            1013..1067
                     /gene="Pidd1"
                     /gene_synonym="Lrdd; Pidd"
                     /inference="alignment:Splign:2.1.0"
     exon            1068..1269
                     /gene="Pidd1"
                     /gene_synonym="Lrdd; Pidd"
                     /inference="alignment:Splign:2.1.0"
     exon            1270..1401
                     /gene="Pidd1"
                     /gene_synonym="Lrdd; Pidd"
                     /inference="alignment:Splign:2.1.0"
     exon            1402..1581
                     /gene="Pidd1"
                     /gene_synonym="Lrdd; Pidd"
                     /inference="alignment:Splign:2.1.0"
     exon            1582..1729
                     /gene="Pidd1"
                     /gene_synonym="Lrdd; Pidd"
                     /inference="alignment:Splign:2.1.0"
     exon            1730..1865
                     /gene="Pidd1"
                     /gene_synonym="Lrdd; Pidd"
                     /inference="alignment:Splign:2.1.0"
     exon            1866..2016
                     /gene="Pidd1"
                     /gene_synonym="Lrdd; Pidd"
                     /inference="alignment:Splign:2.1.0"
     exon            2017..2140
                     /gene="Pidd1"
                     /gene_synonym="Lrdd; Pidd"
                     /inference="alignment:Splign:2.1.0"
     exon            2141..2259
                     /gene="Pidd1"
                     /gene_synonym="Lrdd; Pidd"
                     /inference="alignment:Splign:2.1.0"
     exon            2260..2373
                     /gene="Pidd1"
                     /gene_synonym="Lrdd; Pidd"
                     /inference="alignment:Splign:2.1.0"
     exon            2374..2573
                     /gene="Pidd1"
                     /gene_synonym="Lrdd; Pidd"
                     /inference="alignment:Splign:2.1.0"
     exon            2574..3321
                     /gene="Pidd1"
                     /gene_synonym="Lrdd; Pidd"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agcttccatc agccttgcct aggcaggctt gcttgacaag ctaggacatg tctggtcccc
       61 gaggaccttc tgtgggtgat ggctgcagtg ttggaggggc cgaagccaga ggaaactgca
      121 gctgctgcag aggatgctgc aagacccaca gtggaggctg tggcttccag gcccggagta
      181 cctattctcc tggctgggaa ccagttgaat ctggacctac gccctggggg ctgccgtcgg
      241 ctgcagtacc tgtgttccca gcagcacaca cagctgctgc aagtggagtt tttgcggctc
      301 agcacccacg aggaccctcg actgctagat gacaccctag ccaaggttcc gtggagtcta
      361 ctgcgccttc gctccctggt cctcaaaggt ggccagagtc ggggtgccct gggtgcttgc
      421 ctccatggta ccctaaccac tctgcctgct agcatgagag acttagcctg cctggcccac
      481 ctagacctga gcttcaacag gctggagaca ctgccgacct gtgtcctgga actgcacagc
      541 ttggatgcct tgctgctttc tcacaactgt ctctcagagc tgccagaggc cctgggggca
      601 ctgcctaccc tcaccttcct cactgtgaca cacaacctcc tggaaagact acccccaaca
      661 ctggggtccc tgtccaccct tcagcgtctt gatctctccg agaaccttct agacaccatc
      721 ccgtctgaga ttggagacct gagcagcctc agggagctca atctggcctc caaccggctg
      781 cagcatctcc cagcttccct tgcggggctg cggtccctgc ggctccttgt tctgcacagc
      841 aacctcttga cctcggtgcc ccctggcttg gcccacctgc cactgatcac tcggcttgac
      901 ctgagggaca accagctcag agacctacct gccgagctac tagacgctcc ctttgtgcgc
      961 ctgcagggga accctctggg cgaggcctct cctgcacccc caagtccccc agacatttcc
     1021 caggttccag aaatgcccag gctattcctg acctcagact tggacagctt ccttgtgact
     1081 ccccatggct gttctgtgac cctggcctgt ggtgtccgcc tacagttccc agcaggagcc
     1141 accaccacac ctatcaccat ccactatcga ctgtggttgc ctgagccagg cctagtctct
     1201 ctgggacctc atgacttcct gcttagtggt gtcctggagc tgcagcctca tggggtggct
     1261 ttccagcaga atgtgagctt atggctgctc tttgtccccc cacgagtccg agtccgtcgt
     1321 tgccgtgagg tagttgtgag aacacggagt gacaacatct ggaatgacct agagacccac
     1381 ctggaggaag aggcccccaa gaggcgttgg gctcgctgcc aggtgcccca cttctcctgg
     1441 ttcctggtcg ttttacgccc agtatccaac acctgcctat taccaccaga gggagcactt
     1501 ctgtgctcct caggtcatcc tggggtcaaa gtcacttttc cccctggggt cacagaagag
     1561 ccccggcaag tctccatgca ggtagtgcat atggctggac tagagctgag agcccttctg
     1621 gaagagtcag aggcggcagt gagccccttg ctgtgccttt cccagagcgg accccccagc
     1681 ttcctacaac ctgtcactgt gcagttgccc ttgccccccg gtgttacagg cttcagtctg
     1741 gaccgctccc acttacatct gctctaccga acacccctga caagcacctg ggatgacatc
     1801 agcactcagg tggcactgga attcacccac ctgtacgcac gcttccaggt cacacacttc
     1861 tcctggtact ggctctggta taccaccaaa acctgcgtgg ggggcctggc ccggaaggcc
     1921 tgggaacggc tgcggctgca ccgtgtaaac ctcattgcac tgcagaggcg ccgagacccg
     1981 gagcaggtcc tgctgcagtg cctgccccgg agcaaggtag atgccaccct gagccggctg
     2041 ctggatcggt accgtggccc ggaaccctct gagactgtgg agatgtttga gggtgagaag
     2101 ttctttgcag cctttgagcg gggcatcgat gtagatgctg accgtccaga ctgtgtggat
     2161 ggcagaatct gttttgtctt ctattcacac ctgaagaata tgaaggaggt atacattacc
     2221 acagccttgg accgtgaagc tcaggatgtt cgaggacagg tgtcctttta tcggggttca
     2281 cttcccatgg aggtgcctga agaggcagag gctgcccggc ggaggaaggg cacagatgca
     2341 ttgtggatgg ccaccttgcc catcaagcta ccgagactcc ggggggccca ggggagtggg
     2401 cagggaactg acttctcctt gatgcctctg aacctgggtg atgcagaaac tggattcctg
     2461 actcagagca acctgctgag tgtggcctca cgccttggtt ctgactggcc gactgtggcc
     2521 ctgcacctag gcatgcccta ccgtaagctt cagcgtatcc gacatgaatt cagggatgac
     2581 ctggatgggc agatccgcca catgctcttc tcttgggctg agagccagac tggacagcct
     2641 ggagctgtgg gacacctggt gcaggccttg gagcagagtg accggcagga tgtggctgaa
     2701 gaggtgcgtg ccatcttgga acttggccgt cacaagtacc aggacagcat tcggcgcaca
     2761 gggctggccc ctgaggattc cactctgcct agcacctcag ctttacagaa cccagagtct
     2821 gcacaggcct aggcttacag acttaagata gccttaaact tgacttggcc agtgggcaga
     2881 gccctatcct tctacctcgc ctgtgtggta cagtgcacca gcacacaaaa accctccact
     2941 gtctaggcca agctagcctc caactctcaa tgagtacgtc tcagagattg ttttacttaa
     3001 agaacagaga gtgggttgtc taagtgatct gaagcctggt ccctgtgtgt gcctatgctt
     3061 gccaccatgt caggtcctcc tgctaagatg ggggcagaga gagtctggag agagggctca
     3121 gctgttaaca gcattggctg ctccttcagg gaacccagtt tcagttccca ttacctccat
     3181 gatgactcgt gacagtctgt gactccagtt tggatagatc aacaccttcc tctggcctcc
     3241 acagacacca ggcacacgtg gtgtgccgac atacaggcag gcaaaacatc catacatata
     3301 aaataaaagc tatttattgt g
//
