LOCUS       NM_001106917            1359 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus peptidase inhibitor 15 (Pi15), mRNA.
ACCESSION   NM_001106917 XM_001062143 XM_237257
VERSION     NM_001106917.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1359)
  AUTHORS   Falak S, Schafer S, Baud A, Hummel O, Schulz H, Gauguier D, Hubner
            N and Osborne-Pellegrin M.
  TITLE     Protease inhibitor 15, a candidate gene for abdominal aortic
            internal elastic lamina ruptures in the rat
  JOURNAL   Physiol Genomics 46 (12), 418-428 (2014)
   PUBMED   24790086
  REMARK    GeneRIF: Decreased aortic Pi15 expression, at some point can lead
            to the development of the abdominal aortic internal elastic lamina
            ruptures.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473984.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_237257.3, XM_001062143.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN16676789
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1359
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q11"
     gene            1..1359
                     /gene="Pi15"
                     /note="peptidase inhibitor 15"
                     /db_xref="GeneID:301489"
                     /db_xref="RGD:1309577"
     exon            1..48
                     /gene="Pi15"
                     /inference="alignment:Splign:2.1.0"
     exon            49..356
                     /gene="Pi15"
                     /inference="alignment:Splign:2.1.0"
     CDS             84..860
                     /gene="Pi15"
                     /note="protease inhibitor 15"
                     /codon_start=1
                     /product="peptidase inhibitor 15 precursor"
                     /protein_id="NP_001100387.1"
                     /db_xref="GeneID:301489"
                     /db_xref="RGD:1309577"
                     /translation="MVMISAVNLVILLSLLCEARTIVLLNFTDSSLPANNFSDIEATL
                     SVPVLSVDIPKARRKRYISQNDMIAILDYHNQVRGKVFPPAANMEYMVWDENLAKSAE
                     AWAATCIWDHGPSYLLRFLGQNLSVRTGRYRSILQLVKPWYDEVKDYAFPYPQDCNPR
                     CPMRCFGPMCTHYTQMVWATSNRIGCAIHTCQNMNVWGSVWRRAVYLVCNYAPKGNWI
                     GEAPYKVGVPCSSCPPSYGGACTDNLCFPGVTTNYLYWFK"
     exon            357..475
                     /gene="Pi15"
                     /inference="alignment:Splign:2.1.0"
     exon            476..608
                     /gene="Pi15"
                     /inference="alignment:Splign:2.1.0"
     exon            609..724
                     /gene="Pi15"
                     /inference="alignment:Splign:2.1.0"
     exon            725..1359
                     /gene="Pi15"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acttaccttg ttggaggagc agtgtattca ttttggcatt gtgcagagca aagcaaacct
       61 ggaggacttc tccatccctg aaaatggtaa tgatctctgc agtcaacctt gtgatccttt
      121 tgtcccttct ctgtgaagca cgcactatcg tcttactaaa tttcactgac tcatctctgc
      181 cagccaataa cttctctgat attgaagcca ccctcagcgt accagtactg tctgtggata
      241 tccccaaagc caggcggaag cgctacattt ctcagaatga catgatcgcc attcttgatt
      301 accataatca agttcggggc aaagtgttcc caccagcagc aaacatggaa tatatggtct
      361 gggatgaaaa tcttgcaaaa tcagctgagg catgggcagc aacttgcatt tgggaccatg
      421 gaccttctta cttgctgaga tttttgggtc agaatttgtc tgtacgaact ggaagatatc
      481 gctctattct ccagttggtc aaaccatggt atgatgaagt gaaagattat gcctttcctt
      541 accctcagga ctgcaaccct cggtgtccta tgcgctgctt tgggcccatg tgcactcatt
      601 atacacagat ggtttgggcc acttctaatc gaataggatg tgcaattcac acctgtcaaa
      661 acatgaatgt ctggggatct gtgtggcgac gagcagtgta tttggtctgc aactatgctc
      721 caaagggcaa ctggattgga gaagcaccgt acaaagttgg agtgccatgt tcatcttgtc
      781 ccccgagtta tggtggagcc tgtactgaca atctgtgctt tccaggggta acaacaaact
      841 acctgtactg gtttaaataa gcttttcttt ttcccctcag agggaataca ttggttagtg
      901 gagatatata tatatatata tatatatata tatatatata tatatatgtg tgtgtgtgtg
      961 tgtgtgtgtg tgtgtgtgtg tattgagttt gaacatgtta tatttgcttt agtgtaatcc
     1021 tgttttcatt ttaattatca agtttctagt gtttgtctag agtgttaatt cttagattca
     1081 agcaaaacat cattttctac ttttgacctt caatttaaat taattactgt atttgtagtg
     1141 atgacacagt tgttgcatcc aatcccagga cctacaatcc agagaattat gttattatga
     1201 ccccaaagaa tgcaatgtat attcgagcta taatatatgt atattatatg tatacacatg
     1261 tatagatatg ctcacatgta tgatgtatga tgtgacacat aggtaataac atgatatggt
     1321 agttaacagg ggaaaattaa taatatattt gagattata
//
