LOCUS       NM_001128196            1605 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus 5-phosphohydroxy-L-lysine phospho-lyase (Phykpl),
            mRNA.
ACCESSION   NM_001128196 XM_008767647
VERSION     NM_001128196.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1605)
  AUTHORS   Fragoza,R., Das,J., Wierbowski,S.D., Liang,J., Tran,T.N., Liang,S.,
            Beltran,J.F., Rivera-Erick,C.A., Ye,K., Wang,T.Y., Yao,L., Mort,M.,
            Stenson,P.D., Cooper,D.N., Wei,X., Keinan,A., Schimenti,J.C.,
            Clark,A.G. and Yu,H.
  TITLE     Extensive disruption of protein interactions by genetic variants
            across the allele frequency spectrum in human populations
  JOURNAL   Nat Commun 10 (1), 4141 (2019)
   PUBMED   31515488
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1605)
  AUTHORS   Florea,L., Di Francesco,V., Miller,J., Turner,R., Yao,A.,
            Harris,M., Walenz,B., Mobarry,C., Merkulov,G.V., Charlab,R.,
            Dew,I., Deng,Z., Istrail,S., Li,P. and Sutton,G.
  TITLE     Gene and alternative splicing annotation with AIR
  JOURNAL   Genome Res 15 (1), 54-66 (2005)
   PUBMED   15632090
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On or before Jun 1, 2021 this sequence version replaced
            XM_008767647.3, NM_001128196.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079163.1, SRR26360194.1032461.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-81                JAXUCZ010000010.1  36340957-36341037
            82-200              JAXUCZ010000010.1  36341696-36341814
            201-360             JAXUCZ010000010.1  36342776-36342935
            361-435             JAXUCZ010000010.1  36347442-36347516
            436-523             JAXUCZ010000010.1  36347994-36348081
            524-640             JAXUCZ010000010.1  36348159-36348275
            641-723             JAXUCZ010000010.1  36350136-36350218
            724-949             JAXUCZ010000010.1  36350629-36350854
            950-1104            JAXUCZ010000010.1  36355343-36355497
            1105-1194           JAXUCZ010000010.1  36355711-36355800
            1195-1325           JAXUCZ010000010.1  36356669-36356799
            1326-1379           JAXUCZ010000010.1  36357684-36357737
            1380-1605           JAXUCZ010000010.1  36358240-36358465
FEATURES             Location/Qualifiers
     source          1..1605
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q22"
     gene            1..1605
                     /gene="Phykpl"
                     /gene_synonym="Agxt2l2"
                     /note="5-phosphohydroxy-L-lysine phospho-lyase"
                     /db_xref="GeneID:100169747"
                     /db_xref="RGD:2293818"
     exon            1..81
                     /gene="Phykpl"
                     /gene_synonym="Agxt2l2"
                     /inference="alignment:Splign:2.1.0"
     CDS             23..1468
                     /gene="Phykpl"
                     /gene_synonym="Agxt2l2"
                     /EC_number="4.2.3.134"
                     /note="alanine-glyoxylate aminotransferase 2-like 2"
                     /codon_start=1
                     /product="5-phosphohydroxy-L-lysine phospho-lyase"
                     /protein_id="NP_001121668.2"
                     /db_xref="GeneID:100169747"
                     /db_xref="RGD:2293818"
                     /translation="MAADRRAKAATLDLRRRLLSSSCRLFFPENPVKIIRGQGQYLYD
                     EQGREYLDCINNVAHVGHCHPTVVQAAHEQNLVLNTNSRYLHDNIVDYAQRLSETLPE
                     KLSVFYFLNSGSEANDLALRLARQYTGHQDVVVLDHAYHGHLSSLIDISPYKFRNLDG
                     QKEWVHVAPLPDTYRGPYREDHPDPAGAYASEVKHVISSAQKKGRKIAAFFAESLPSV
                     SGQIIPPAGYFSQVAEHIRRAGGLFVADEIQVGFGRVGKHFWAFQLEGEDFVPDIVTM
                     GKSIGNGHPVACLATTQAVSRAFEATGVEYFNTFGGNPVSCAVGLAVLDVLKTEQLQA
                     HATNVGSFLMEHLSQQKAKHPIIGDVRGTGLFIGVDLIKDETLRTPATEEAEYLVSRL
                     KENYILLSTDGPGRNILKFKPPMCFSLDNAQHVVAKLDDILTDMEEKVRSCETLRIKH
                     PPGSTGPGCRAAAGSRPSNLEQGNLVIKSAP"
     exon            82..200
                     /gene="Phykpl"
                     /gene_synonym="Agxt2l2"
                     /inference="alignment:Splign:2.1.0"
     exon            201..360
                     /gene="Phykpl"
                     /gene_synonym="Agxt2l2"
                     /inference="alignment:Splign:2.1.0"
     exon            361..435
                     /gene="Phykpl"
                     /gene_synonym="Agxt2l2"
                     /inference="alignment:Splign:2.1.0"
     exon            436..523
                     /gene="Phykpl"
                     /gene_synonym="Agxt2l2"
                     /inference="alignment:Splign:2.1.0"
     exon            524..640
                     /gene="Phykpl"
                     /gene_synonym="Agxt2l2"
                     /inference="alignment:Splign:2.1.0"
     exon            641..723
                     /gene="Phykpl"
                     /gene_synonym="Agxt2l2"
                     /inference="alignment:Splign:2.1.0"
     exon            724..949
                     /gene="Phykpl"
                     /gene_synonym="Agxt2l2"
                     /inference="alignment:Splign:2.1.0"
     exon            950..1104
                     /gene="Phykpl"
                     /gene_synonym="Agxt2l2"
                     /inference="alignment:Splign:2.1.0"
     exon            1105..1194
                     /gene="Phykpl"
                     /gene_synonym="Agxt2l2"
                     /inference="alignment:Splign:2.1.0"
     exon            1195..1325
                     /gene="Phykpl"
                     /gene_synonym="Agxt2l2"
                     /inference="alignment:Splign:2.1.0"
     exon            1326..1379
                     /gene="Phykpl"
                     /gene_synonym="Agxt2l2"
                     /inference="alignment:Splign:2.1.0"
     exon            1380..1605
                     /gene="Phykpl"
                     /gene_synonym="Agxt2l2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gactgactga ccgctcggcg ccatggccgc ggaccggcgc gccaaggccg ccactctgga
       61 cctgagacgt cggctgctca gctcttcctg cagactcttt tttcctgaga atcctgttaa
      121 gattatccga ggccaagggc agtacttgta tgatgagcaa gggcgagagt acctggactg
      181 catcaacaat gtggctcatg tcgggcactg ccaccctacc gtggtccaag ctgcacatga
      241 acagaacctg gtgctcaaca ccaacagccg atatctacat gacaacatcg tggactatgc
      301 ccagaggctg tcagagaccc tgccagagaa gctttctgtg ttttatttcc tgaattctgg
      361 gtcagaagcc aacgacctgg ccttgagact agctcgccag tacacaggac accaggatgt
      421 ggtggtatta gaccatgctt atcatggtca cctgagctca ttgatcgaca tcagtcccta
      481 caagttccgg aatctggatg gccagaagga atgggtccat gtggctccgc tcccagacac
      541 ctaccgggga ccttaccggg aggaccaccc cgatccagca ggggcctatg ccagtgaggt
      601 gaagcatgtc atcagcagtg cacagaagaa gggcaggaag attgcagcct tcttcgccga
      661 gtctctgcct agtgtgagtg gacagatcat tccccctgct ggatacttct cccaggtggc
      721 ggagcacata cgcagagccg gagggctctt tgtggctgat gagatccagg ttggttttgg
      781 ccgagtaggc aaacactttt gggccttcca gctggaggga gaagactttg tccccgacat
      841 tgtcaccatg ggcaagtcca tcggcaatgg tcatcctgtt gcctgcctgg ccactaccca
      901 agctgtgtca agggcatttg aagctaccgg tgtagaatac ttcaacacgt ttggtggcaa
      961 tcctgtgtcc tgtgctgtgg ggctagcagt cctggatgtc ttgaaaacag aacagctcca
     1021 ggctcatgcc actaatgtgg gcagcttcct tatggagcac ctcagccagc agaaagccaa
     1081 acatcctatc attggagatg tcaggggcac tgggctcttc attggtgtgg atctgatcaa
     1141 ggatgagact ctgaggacac cagcaactga agaggcagag tatttggtct ccaggctaaa
     1201 ggaaaactac attttactga gcactgacgg ccctgggagg aatatcctga agttcaagcc
     1261 tccaatgtgc ttcagccttg ataacgcaca gcatgtggtt gcaaagctgg atgacattct
     1321 aacagacatg gaagaaaaag tacgaagttg tgaaacactg aggatcaaac accctccagg
     1381 gtccacaggt ccaggctgca gagcggcagc aggaagcaga ccctccaatc tagaacaggg
     1441 taacctggta ataaaatcag ccccctaatg ccgctctgac ctctgagacg ccacacgctg
     1501 cctacaacaa ctagagctct ggaatagtaa acaggagagt gatttccggg ggaaatttta
     1561 aataagatgc acatgggaca ggccataaaa gtttgccaag ttaaa
//
